不可逆性歯髄炎に対する一回限りの根管治療の治療効果について

Therapeutic effect of one-time root canal treatment for irreversible pulpitis.

抄録

目的:

不可逆性歯髄炎に対する1回の根管治療と2回の根管治療の治療効果を比較すること。

OBJECTIVE: To compare the therapeutic effects of one-time root canal treatment versus two-time treatment in patients with irreversible pulpitis.

研究方法:

130例の患者を、来院回数により1回治療群（A群；n=68）と2回治療群（B群；n=62）に分類した。6ヵ月後と1年後の経過観察時の臨床効果と、歯内療法前と1週間後のインターロイキン6、腫瘍壊死因子α、高感度C反応性蛋白の血清レベルを観察した。さらに，両群の治療満足度を比較し，痛みの程度をvisual analogue scaleで評価した。

METHODS: We classified 130 patients into a one-time treatment group (group A; n = 68) and a two-time treatment group (group B; n = 62) according to the number of patient visits. Clinical efficacy at 6 months and 1 year follow-ups as well as serum levels of interleukin-6, tumor necrosis factor alpha, and high-sensitivity C-reactive protein before and 1 week after endodontic treatment were observed. Additionally, the level of treatment satisfaction between the two groups was compared, and the degree of pain was evaluated using the visual analogue scale.

結果:

歯内治療の1週間後には，両群ともにインターロイキン6，腫瘍壊死因子α，高感度C反応性蛋白が有意に減少したが，B群はA群よりも有意に低かった．

RESULT: One week after treatment, serum interleukin-6, tumor necrosis factor alpha, and high-sensitivity C-reactive protein levels were significantly decreased in the two groups; however, levels in group B were significantly lower than those in group A. Additionally, visual analogue scale scores of patients in group A were significantly higher than those of patients in group B.

結論:

一回法による根管治療は，術後の痛みや治療中の患者の血清中の炎症性因子の発現を効果的に改善することができる。

CONCLUSION: One-time root canal therapy can effectively improve postoperative pain and the expression of inflammatory factors in the serum of patients undergoing treatment.