歯内療法における三酸化無機凝集体の臨床効果の比較分析

Comparative Analysis of Clinical Effects of Mineral Trioxide Aggregate in the Treatment of Endodontic Diseases.

抄録

背景:

歯内療法における三酸化無水物骨材（MTA）の有効性を検討することを目的とした。

BACKGROUND: We aimed to evaluate the efficacy of mineral trioxide aggregate (MTA) in the treatment of endodontic disease.

方法:

2015年6月から2017年6月までに中国徐州市の徐州口腔科病院で治療した歯内疾患患者384人を選び、無作為に4群に分け、1群96例とした。4群の患者の歯と歯髄に対するMTA、リン酸亜鉛セメント（ZPC）、銀アマルガム、光硬化型水酸化カルシウム（LCH）の修復効果を比較検討した。また，患者の症状を観察し，症状が緩和されるかどうかを確認した．また，修復効果が患者の年齢，病変歯の穿孔径，修復材料と関連しているかどうかを検討した．

METHODS: Oversell, 384 patients with endodontic disease treated in Xuzhou Stomatological Hospital, Xuzhou, China, from June 2015 to June 2017 were selected, and randomly divided into four groups with 96 cases per group. The repair effects of MTA, zinc phosphate cement (ZPC), silver amalgam and light-curing calcium hydroxide (LCH) on the teeth and dental pulp of patients in the four groups were compared. Meanwhile, the ill symptoms of the patients were observed to confirm whether they could be alleviated. Besides, whether the repair effects were related to ages of patients, perforation diameters of diseased teeth and repair materials was discussed.

結果:

MTA群，ZPC群，LCH群，銀アマルガム群の成功率は，それぞれ90.6％，68.7％，70.8％，52.1％であり，MTA群，ZPC群，LCH群，銀アマルガム群の方が成功率が高かった．MTA群の成功率は，ZPC群，銀アマルガム群，LCH群に比べ有意に高かった．4群の成功率を比較すると，その差は統計的に有意であった（=0.0072）．患者の年齢，修復材料，穿孔径は，MTA修復効果と正の相関を示した（=0.003, =0.002, =0.01）．各群の患者の歯は異なる材料で修復され，4週間後に再検査が行われた．銀アマルガム群では3名の患者に歯肉の腫脹が認められた．

RESULTS: The success rates of MTA group, ZPC group, LCH group and silver amalgam group were 90.6%, 68.7%, 70.8% and 52.1%, respectively. The success rate of MTA group was significantly higher than that of ZPC group, silver amalgam group and LCH group. When the success rates of four groups were compared, the differences were statistically significant (=0.0072). The patient's age, repair material and perforation diameter were positively correlated with MTA repair effect (=0.003, =0.002, =0.01). The patients' teeth in each group were repaired with different materials, and the reexamination was conducted 4 weeks later. Three patients in the silver amalgam group were found to have gingival swelling.

結論:

MTA の治療効果は歯内療法において顕著であり，臨床応用に値すると考えられた．

CONCLUSION: The therapeutic effect of MTA was significant in the treatment of endodontic disease, and it is worthy of clinical application.