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二層分光検出器CTを用いた放射線学的に不確定な局所結腸壁肥厚の定量的評価
Quantitative Assessment of Radiologically Indeterminate Local Colonic Wall Thickening on Iodine Density Images Using Dual-Layer Spectral Detector CT.
PMID: 32622742 DOI: 10.1016/j.acra.2020.06.012.
抄録
理由と目的:
二層分光検出器CT(DLSCT)を用いて、ヨウ素濃度画像上で局所的な大腸壁肥厚(LCWT、厚さ3mm以上、長さ5cm未満)を定量的に評価すること。
RATIONALE AND OBJECTIVES: To assess local colonic wall thickening (LCWT, thicknesses: >3 mm, lengths: <5 cm) quantitatively on iodine density images using dual-layer spectral detector computed tomography (DLSCT).
材料と方法:
このレトロスペクティブ研究では,従来の造影CTと大腸内視鏡検査の両方を1ヶ月以内に受けた80人の患者を対象とした.ヨウ素濃度画像モデルを用いて、選択した画像上に関心領域を描出した。病変部のヨード濃度(IC)、正規化IC(NIC)、および病変部の大腸壁の厚さを病変群と非病変群で比較した。
MATERIALS AND METHODS: This retrospective study included 80 patients who underwent both conventional contrast-enhanced CT and colonoscopy within one month. The region of interest was delineated on the chosen images with the iodine density image model. The iodine concentration (IC), normalized IC (NIC), and thickness of the colonic wall in the lesion area were compared between the pathological and nonpathological groups.
結果:
CT検査でLCWTが検出された患者のうち、大腸内視鏡検査で結腸新生物と診断された患者は50例であった。他の30例はCT画像上でLCWTが認められたが、大腸内視鏡検査では正常であった。大腸壁の厚さは、病理学的 LCWT 群と非病理学的 LCWT 群の間に有意差はなかった(p> 0.05)。大腸新生物を有する患者のICおよびNICは、非病理学的LCWT群と比較して有意に高かった(いずれもp<0.001)。ROC曲線から、ICおよびNIC値が1.49 mg/mL、0.33の場合、結腸新生物を診断する感度は91.5%、特異度は75.8%、結腸新生物を診断する感度は85.1%、特異度は84.8%となり、結腸新生物を診断する感度は1.49 mg/mL、特異度は0.33であった。
RESULTS: There were 50 patients whose area of LCWT discovered at CT scans displayed colon neoplasia at colonoscopy. The other 30 patients with LCWT on CT images showed normal appearances during colonoscopy. There was no significant difference in colonic wall thickness between the pathological and nonpathological (p> 0.05) LCWT groups. The IC and NIC of patients with colon neoplasms were significantly higher than those with nonpathologic LCWT (both p< 0.001). The ROC curve showed that when IC and NIC was 1.49 mg/mL and 0.33, the sensitivity and specificity for diagnosing colon neoplasm were 91.5% and 75.8%, 85.1% and 84.8%, respectively.
結論:
また、DLSCTのIC値とNIC値は、結腸新生物によるLCWTの診断に十分な値を与えることができた。
CONCLUSION: IC and NIC values from DLSCT could provide a satisfied diagnostic value to identify LCWT caused by colon neoplasia.
Copyright © 2020 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.