TORSADES DE POINTES IN ELDLEY PATIENT WITH PAROXYSMAL ATRIAL FIBRILLATION TREATED BY SHORTTERMENTERAL PARENTERAL AMIODARONE THERAPY

TORSADES DE POINTES IN ELDERLY PATIENT WITH PAROXYSMAL ATRIAL FIBRILLATION TREATED BY SHORT-TERM PARENTERAL AMIODARONE THERAPY.

• Nenad Lakušić
• Valentina Slivnjak
• Nedeljko Ciglenečki
• Duško Cerovec

抄録

心房細動の治療に広く用いられている薬剤の一つにアミオダロンがあります。アミオダロンは、補正されたQT間隔がかなり延長し、かなりの程度の徐脈がみられるにもかかわらず、長期使用後のほとんどの場合、不整脈イベントの発生頻度は著しく低く、Torsades de pointesの発生率は1.0％未満である。発作性発作性心房細動に急性心不全を合併し，アミオダロンの短期非経口投与によりtorsades de pointesを発症した80歳女性の1例を紹介する。

One of the drugs that are widely used in the treatment of atrial fibrillation is amiodarone. Despite considerable prolongation of the corrected QT interval and a substantial degree of bradycardia, amiodarone exhibits a remarkably low frequency of pro-arrhythmic events and <1.0% incidence of torsades de pointes, mostly after long-term usage. We present a case of an 80-year-old female with paroxysmal atrial fibrillation accompanied by acute heart failure treated by short-term parenteral amiodarone therapy and development of torsades de pointes.