日本語AIでPubMedを検索
韓国パンデミック初期のコロナウイルス疾患2019の4例：公立病院の1例の経験
Four cases of coronavirus disease 2019 in the early stage of pandemic of South Korea: a single public hospital experience.
PMID: 32668515 DOI: 10.3904/kjim.2020.079.
抄録
このパンデミックに鑑み、2020年2月現在、韓国では世界で2番目に多くの確定症例が発生している。ここでは、韓国におけるパンデミックの初期段階のコロナウイルス疾患2019（COVID-19）の確定症例4例を報告し、1例の患者の初期軽度症状の呈示時と発病21日目の肺炎への進行を含む、同定、診断、臨床経過、管理について説明する。入院後48時間以内に、4人の患者全員が初期の臨床検査値、COVID-19ポリメラーゼ連鎖反応（PCR）、胸部CT（Computed Tomography）所見の評価を受けた。軽度のCOVID-19患者4人全員が退院し、退院後14日後に再検査を受けた。4人とも無症状であったが，PCRウイルス核酸検出によりCOVID-19を確認した1人が再入院した．彼女は7日後に24時間間隔で2回のCOVID-19 PCR陰性を示し、退院することができた。軽度のCOVID-19を有する患者は、たとえ初期の胸部CTが明らかに肺炎を示していたとしても、一般に退院後のフォローアップ胸部CTスキャンは正常である。退院後にCOVID-19 PCR陽性の再入院患者は、他の3人の患者と比較して、初期の胸部CT、検査室、症状とは無関係であった。
In view of this pandemic, as of February 2020, South Korea has the second highest number of confirmed cases in the world. Herein, we report four confirmed coronavirus disease 2019 (COVID-19) cases in the early stage of the pandemic in South Korea and describe the identification, diagnosis, clinical course, and management, including one patient's initial mild symptoms at presentation and their progression to pneumonia on day 21 of illness. Within 48 hours of hospitalization, all four patients underwent evaluation for initial laboratory parameters, COVID-19 polymerase chain reaction (PCR), and chest computed tomography (CT) findings. All four mild COVID-19 patients were discharged, and they were re-examined 14 days after discharge. Despite all four of them being asymptomatic, one patient was re-admitted after confirmation of COVID-19 through PCR viral nucleic acid detection. She could be discharged after 7 days with two subsequent negative COVID-19 PCR at 24-hour intervals. Patients with mild COVID-19 generally have normal follow-up chest CT scans after discharge, even if the early chest CT definitely indicates pneumonia. Re-hospitalized patients with COVID-19 PCR positive results after discharge were not related to her initial chest CT, lab, symptoms compared other three patients.