川崎病-COVID-19の小児への新たな症状

[Kawasaki disease - a new manifestation of COVID-19 in children].

• Fu-Yong Jiao

抄録

欧米でコロナウイルス感染症2019（COVID-19）が発生して以来、川崎病の発症率が大幅に増加しており、小児科医や保護者の間で懸念が高まっています。COVID-19は、川崎病の全身血管炎に似た複数の臓器の炎症反応を起こし、COVID-19でも手足の四肢に皮膚発疹を起こすことがありますが、これも川崎病に似ています。川崎病の原因は現在のところ不明であり、COVID-19が川崎病の発症率の増加と関連しているとは断定できません。したがって、COVID-19の流行期には、小児に川崎病に類似した症状がみられた場合には、冠動脈病変の発症を抑えるために、早期に免疫グロブリンの静脈内投与を行うことが推奨されています。

Since the outbreak of coronavirus disease 2019 (COVID-19) in Europe and America, the incidence of Kawasaki disease has significantly increased, which has aroused concern among pediatricians and parents. COVID-19 can cause inflammation reactions of multiple organs, which is similar to the systemic vasculitis of Kawasaki disease, and even COVID-19 can cause skin rash on the extremities of the limbs, which is also similar to Kawasaki disease. The cause of Kawasaki disease is currently unclear, and it cannot be ruled out that COVID-19 is associated with an increased incidence of Kawasaki disease. Therefore, during the epidemic of COVID-19, if children have symptoms similar to Kawasaki disease, intravenous immunoglobulin is recommended as early as possible to reduce the incidence of coronary artery lesions.