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TheraCal LCの限界適応性、溶解性、生体適合性をMTA-アンジェラスおよびバイオデンチンと比較した、裂孔修復材料としてのTheraCal LCの限界適応性、溶解性、生体適合性
Marginal adaptation, solubility and biocompatibility of TheraCal LC compared with MTA-angelus and biodentine as a furcation perforation repair material.
PMID: 33121465 DOI: 10.1186/s12903-020-01289-y.
抄録
背景:
この研究では、TheraCal LCの限界適応性、溶解性、および生体適合性をミネラル三酸化物骨材（MTA-Angelus）およびBiodentineと比較して評価しました。
BACKGROUND: This study evaluated the marginal adaptation, solubility and biocompatibility of TheraCal LC compared with mineral trioxide aggregate (MTA-Angelus) and Biodentine when used as a furcation perforation repair material.
方法:
限界適応は走査型電子顕微鏡で評価し、試料の各象牙質表面と充填材との間に隙間があるかどうかを１００００×倍率で分析した。溶解度は1週間後にISO標準法で測定した。生体適合性は、犬の歯の実験的なファーカチオン穿孔を修復した1ヶ月後と3ヶ月後の炎症反応とX線写真で評価した。
METHODS: The marginal adaptation was assessed by scanning electronic microscope and presence of any gap between the dentin surface and filling material in each quadrant of the sample was analyzed at 1000 X magnification. The solubility was measured after one week by the ISO standard method. Biocompatibility was evaluated by the inflammatory response and radiography after one month and three months of repair of experimental furcation perforations in dog's teeth.
結果:
試験した材料の限界適応性、溶解性、生体適合性には有意な差があった（P<0.05）。TheraCal LCはギャップの存在頻度が最も高く、MTA-Angelus、Biodentineの順であった。1週間後に最も溶解性が低かったのはTheraCal LCで、MTA-Angelus、Biodentineの順であった。1ヶ月後と3ヶ月後には、TheraCal LCが最も高い炎症反応を示し、放射性物質の頻度分布が最も高く、Biodentine、MTA-Angelusの順であった。
RESULTS: There were significant differences in the marginal adaptation, solubility and biocompatibility of the tested materials (P < 0.05). TheraCal LC showed the highest frequency distribution of gap presence that was followed by the MTA-Angelus then Biodentine. The least soluble material after one week was TheraCal LC that was followed by the MTA-Angelus and Biodentine. After one month and three months, TheraCal LC showed the highest inflammatory response and highest frequency distribution of radiolucency that was followed by the Biodentine then MTA-Angelus.
結論:
バイオデンチンとは異なり、TheraCal LCは生体適合性が低く、限界適応性が低いため、ファーケーション穿孔修復においてMTAを交互に使用することができません。
CONCLUSION: Unlike Biodentine, TheraCal LC is incapable of alternating the MTA in furcation perforation repair due to its poor biocompatibility and poor marginal adaptation.