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上顎骨の副鼻腔の調査:先天性の変異か後天性の欠損か?
Investigation of the accessory maxillary ostium: a congenital variation or acquired defect?
PMID: 33591847
抄録
目的:
我々は、上顎骨副鼻腔(AMO)が先天的なものか後天的なものかを判断することを目的とし、この構造に関連する副鼻腔の病理を調査した。
OBJECTIVE: We sought to determine whether an accessory maxillary ostium (AMO) is a congenital or acquired condition and we investigated concomitant sinus pathologies associated with this structure.
方法:
13歳以上と13歳未満の人の副鼻腔のCT検査をレトロスペクティブに比較した。13歳以上の患者276名の552個の副鼻腔(グループ1)と、13歳未満の小児142名の上顎洞284個(グループ2)を評価した。患者はAMO陽性または陰性に分類された。グループ1では,AMOの存在,粘液貯留嚢胞,粘膜肥厚,上顎洞の副鼻腔炎,鼻中隔の逸脱, concha hyperphy, concha bullosa,primary ostium obstruction, uncinate process atelectasis, paradox concha, Agger nasi and Haller cell, sinus hypoplasiaなどの特徴を評価した。AMOの大きさと位置も評価した。グループ2では、AMOと副鼻腔炎の有無を評価した。
METHODS: Paranasal sinus CT examinations of individuals aged ≥13 years and <13 years were compared retrospectively. In total, 552 sinuses of 276 patients aged ≥13 years (Group 1) and 284 maxillary sinuses of 142 children aged <13 years (Group 2) were evaluated. Patients were classified as AMO-positive or -negative. The following features were evaluated in Group 1: AMO presence, mucus retention cysts, mucosal thickening, sinusitis of the maxillary sinus, nasal septum deviation, concha hypertrophy, concha bullosa, primary ostium obstruction, uncinate process atelectasis, paradox concha, Agger nasi and Haller cells, and sinus hypoplasia. The sizes and locations of AMOs were also evaluated. The presence of an AMO and sinusitis were evaluated in Group 2.
結果:
AMO陽性群では、副鼻腔炎、粘膜肥厚、原発性鼻孔閉塞が、AMO陰性群に比べて有意に多かった(p < 0.00001)。AMOの存在と他のパラメータとの間には,統計的に有意な関連は認められなかった。グループ2では2つの副鼻腔にAMOが存在した。
RESULTS: AMOs were detected in 122 sinuses in Group 1. In the AMO-positive group, sinusitis, mucosal thickening, and primary ostium obstruction were significantly more common than in the AMO-negative group (p < 0.00001). Statistically significant associations were not observed between AMO presence and other parameters. AMOs were present in two sinuses in Group 2.
結論:
今回の結果から,AMOは副鼻腔疾患によって生じる後天的な欠陥であることが示唆された。13歳未満の患者にこれらの構造物がまれに見られることから,副鼻腔炎または原発性オステオウム閉塞の患者における穿孔または二次的な排水経路である可能性が示唆された。
CONCLUSION: Our results suggest that AMOs are acquired defects caused by sinus diseases. The rare occurrence of these structures in patients aged <13 years suggests that they may be a perforation or secondary drainage pathway in patients with sinusitis or primary ostium obstruction.