口腔乾燥症患者の口腔衛生関連QOLとその関連因子の検討

Oral health-related quality of life and associated factors in patients with xerostomia.

• Jee-Hye Choi
• Moon-Jong Kim
• Hong-Seop Kho

抄録

目的:

本研究では、口腔乾燥症患者の口腔保健関連QOL（OHRQoL）に関連する臨床的および人口統計学的因子を調査することを目的とした。

OBJECTIVE: This study aimed to investigate clinical and demographic factors associated with oral health-related quality of life (OHRQoL) in patients with xerostomia.

研究方法:

口腔乾燥症を主訴とする41名の患者（55.2±13.8歳）が本研究に参加した。口腔乾燥症質問票を用いて、口腔乾燥症患者の臨床的および人口統計学的特徴、口腔乾燥症に関連する症状や行動、口腔乾燥症に関連する苦情などの包括的な情報を調査した。刺激していない唾液と刺激した唾液の流量を測定した。患者の OHRQoL を評価するために，Oral Health Impact Profile-14（OHIP-14）スコアを用いた．様々な要因とOHIP-14スコアとの関係は，単純および重回帰分析によって評価した．

METHODS: Forty-one patients (55.2 ± 13.8 years) with xerostomia as a chief complaint participated in the study. Comprehensive information about clinical and demographic characteristics of the patients with xerostomia, xerostomia-related symptoms and behaviours, and xerostomia-associated complaints was investigated using a xerostomia questionnaire. Flow rates of unstimulated and stimulated whole saliva were measured. The Oral Health Impact Profile-14 (OHIP-14) score was used to assess the OHRQoL of patients. The relationships between various factors and the OHIP-14 score were assessed by simple and multiple linear regression analyses.

結果:

口腔乾燥症患者のOHIP-14スコアは高かった（44.3±13.2）。OHIP-14スコアが高い口腔乾燥症患者の特徴は，口腔乾燥症関連症状の強さ，口腔乾燥症関連行動の頻度，話しにくさの有無であった．重回帰分析の結果、通常の日常生活における自己申告の唾液量（β＝0.622、p＝0.012）と話しづらさの有無（β＝0.348、p＝0.014）が口腔乾燥症患者のOHRQoLに有意な悪影響を及ぼすことがわかった。

RESULTS: The OHIP-14 score of patients with xerostomia was high (44.3 ± 13.2). Characteristics of the patients with xerostomia associated with high OHIP-14 score were the intensity of xerostomia-related symptoms, frequency of xerostomia-related behaviours and the presence of speaking difficulty. Results from multiple linear regressions found that self-reported amount of saliva in usual, everyday life (β = 0.622, p = 0.012) and the presence of a speaking difficulty (β = 0.348, p = 0.014) had significant adversely affected the OHRQoL in patients with xerostomia.

結論:

口腔乾燥症の患者では、口の中の唾液の量に関する主観的な認識と話しにくさの経験が、OHRQoLに影響を与えていた。

CONCLUSIONS: Subjective perceptions of the amount of saliva in the mouth and the experience of speaking difficulty affected the OHRQoL in patients with xerostomia.

© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.