異なる補綴器具を装着した患者における口腔内カンジダ菌のコロニー形成

Oral Candidal Colonization in Patients with Different Prosthetic Appliances.

抄録

口腔内カンジダ症は，免疫力の低下した患者の増加や，可撤式補綴物などの口腔内環境が良好であることと関連している可能性がある．本研究の目的は、PMMAおよびCr-Co製補綴物を装着した患者における特定の感染症の有無、唾液流量、および口腔内の徴候・症状を明らかにすることである。本調査では，異なる種類の可撤式義歯を装着した計120名の被験者を対象とした．その結果，義歯を装着している被験者のうち，義歯を装着していない被験者に比べて，義歯を装着している被験者のうち，義歯を装着していない被験者に比べて，義歯を装着している被験者に比べて，義歯を装着している被験者に比べて，義歯を装着している被験者に比べて，より多くの菌が検出された（<0.0001）．また，義歯装着者では，( < 0.001 )と( < 0.001 )の有病率に統計的な有意差が認められた．PMMA製可撤式補綴物装着者は，Co-Cr製金属フレームワークの部分床義歯装着者と比較して，唾液分泌量の減少（< 0.001），熱感の増加（< 0.001）およびドライマウス（< 0.001）を認めた．口腔内の赤色病変は，Co-Cr金属フレームワークの部分入れ歯を装着した被験者でより頻繁に認められた（< 0.001）．義歯の材質にかかわらず，口腔内病変の発生を予防するためには，歯科医師による定期的なチェックが必要である．

Oral infections caused by are becoming more common, which may be related to an increase in the number of immunologically compromised patients as well as favorable conditions in the oral cavity that often include removable prosthetic appliances. The purpose of this study was to determine the presence of a particular in patients with PMMA and Cr-Co prosthetic appliances, as well as the salivary flow rate, and oral signs and symptoms. This investigation included a total of 120 subjects with different kinds of removable dentures. A sample of concentrated oral rinse was collected from all subjects in order to detect colonization and identify the species, a quantum of salivation was measured, and subjects were examined clinically. spp. was predominant among the subjects who were denture wearers ( < 0.0001). In all subjects, the most frequently detected species was . A statistically significant difference was found between the prevalence of ( < 0.001) and ( < 0.001) in denture wearers. Subjects with PMMA-based removable prosthetic appliances mostly demonstrated a significant decrease in salivation ( < 0.001), an increase in burning sensations ( < 0.001), and dry mouth ( < 0.001) compared to the subjects who wore partial dentures with Co-Cr metallic frameworks. Red oral lesions were more frequently found among the subjects with partial dentures with Co-Cr metallic frameworks ( < 0.001). Regardless of the material used for the denture, patients must be regularly checked by their dentists in order to prevent the development of oral lesions.