多形性腺癌：その特徴と診断上の課題とともに、症例報告

Polymorphous adenocarcinoma: A case report along with its characteristics and diagnostic challenges.

抄録

多形性腺癌（PAC）は，主に小唾液腺を侵すまれな腫瘍である。口腔内，特に口蓋内に無症状で緩徐に増大する腫瘤として現れることが多く，その臨床挙動は良性新生物と類似しているため，しばしば診断の遅れを引き起こす低悪性度な腫瘍である。本稿では，49歳女性の口蓋垂性多形性腺腫のまれな症例を報告するとともに，多形性腺腫および腺様嚢胞癌の臨床的および顕微鏡的特徴の重複による診断上の課題を簡潔に検討した。

Polymorphous adenocarcinoma (PAC) is an uncommon tumor that affects minor salivary glands mainly. It presents as an indolent malignancy that frequently manifests as an asymptomatic, slow-growing mass within the oral cavity, especially palate and its clinical behavior resembles that of benign neoplasm, often causing delay in the diagnosis. Here, we report a rare case of PAC of palate in a 49-year-old female patient along with a concise review of characteristics of PAC and highlight diagnostic challenges caused by the overlap of clinical and microscopic features between PAC, pleomorphic adenoma and adenoid cystic carcinoma.