過体重または肥満の高齢者における口腔乾燥の増加と口腔保健関連QOLの否定的評価

Increased Oral Dryness and Negative Oral Health-Related Quality of Life in Older People with Overweight or Obesity.

抄録

この横断研究は、肥満のあるタイの高齢者の口腔健康関連QOL（OHRQoL）と口腔の健康指標との関連性を評価するものである。一般的な状態および口腔内の状態を評価した。口腔乾燥は、Xerostomia Inventory-11（XI-11）および臨床口腔乾燥スコア（CODS）を用いて判定した。OHRQoLは、Oral Health Impact Profile（OHIP-14）により評価された。参加者は60～86歳で、73人（59.3％）が過体重または肥満、50人（40.7％）が標準体重であった。肥満のある高齢者は、肥満のない人に比べて、高血圧の割合が約4倍（OR = 3.59; 95%CI:1.34-9.60; = 0.002）、歯の欠損が多く（= 0.025）、CODSが高い（= 0.014）ことがわかった。XI-11の総得点は、BMIで調整した後、CODSの総得点と正の相関があった（= 0.267, = 0.003）。肥満者は非肥満者に比べ、OHRQoLがマイナスになる傾向が3倍近くあった（OR = 2.73; 95%CI:1.12-6.71; = 0.04）．すべての関連因子を調整した後、肥満とXI-11の総スコアに基づいてOHIP-14スコア4を予測する確率は、それぞれ4.42（95％CI：1.57-12.47、=0.005）と1.11（95％CI：1.02-1.20、=0.013）だった。肥満は、タイ人高齢者のOHRQoLにますます望ましくない悪影響を及ぼし、BMIと口腔乾燥に影響された。

This cross-sectional study was to evaluate the association between the oral health-related quality of life (OHRQoL) of older Thai people with obesity and oral health indicators. General and oral conditions were assessed. Oral dryness was determined using the Xerostomia Inventory-11 (XI-11) and clinical oral dryness score (CODS). OHRQoL was evaluated by the oral health impact profile (OHIP-14). Participants were aged 60-86 years; 73 (59.3%) were overweight or obese, and 50 (40.7%) were normal weight. Older patients with obesity had almost four times the rate of hypertension (OR = 3.59; 95%CI:1.34-9.60; = 0.002), more missing teeth ( = 0.025), and higher CODS ( = 0.014) than those without obesity. The total XI-11 scores were positively associated with the total CODS, after adjusting for BMI ( = 0.267, = 0.003). Those with obesity had almost three times the tendency for a negative OHRQoL compared with the non-obese (OR = 2.73; 95%CI:1.12-6.71; = 0.04). After adjusting for all related factors, the chances of predicting an OHIP-14 score of four based on obesity and total XI-11 score were 4.42 (95%CI:1.57-12.47; = 0.005) and 1.11 (95%CI:1.02-1.20; = 0.013), respectively. Obesity had an increasingly undesirable negative impact on the OHRQoL of older Thai people and was influenced by BMI and oral dryness.