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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

2020年07月 みんなが読んでいる論文

FAK活性はプラチナ化学療法に対する本質的および後天的な卵巣癌抵抗性を維持する

FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
  • Carlos J Diaz Osterman
  • Duygu Ozmadenci
  • Elizabeth G Kleinschmidt
  • Kristin N Taylor
  • Allison M Barrie
  • Shulin Jiang
  • Lisa M Bean
  • Florian J Sulzmaier
  • Christine Jean
  • Isabelle Tancioni
  • Kristen Anderson
  • Sean Uryu
  • Edward A Cordasco
  • Jian Li
  • Xiao Lei Chen
  • Guo Fu
  • Marjaana Ojalill
  • Pekka Rappu
  • Jyrki Heino
  • Adam M Mark
  • Guorong Xu
  • Kathleen M Fisch
  • Vihren N Kolev
  • David T Weaver
  • Jonathan A Pachter
  • Balázs Győrffy
  • Michael T McHale
  • Denise C Connolly
  • Alfredo Molinolo
  • Dwayne G Stupack
  • David D Schlaepfer
  • Elife.2019 09;8. e47327. doi: 10.7554/eLife.47327.Epub 2019-09-03.

地中海式ダイエットと更年期の健康。EMASのポジションステートメント

The Mediterranean diet and menopausal health: An EMAS position statement.
  • Antonio Cano
  • Skye Marshall
  • Irene Zolfaroli
  • Johannes Bitzer
  • Iuliana Ceausu
  • Peter Chedraui
  • Fatih Durmusoglu
  • Risto Erkkola
  • Dimitrios G Goulis
  • Angelica Lindén Hirschberg
  • Ludwig Kiesel
  • Patrice Lopes
  • Amos Pines
  • Mick van Trotsenburg
  • Irene Lambrinoudaki
  • Margaret Rees
  • Maturitas.2020 Jul;S0378-5122(20)30325-X. doi: 10.1016/j.maturitas.2020.07.001.Epub 2020-07-13.

未治療の濾胞性リンパ腫を対象としたBendamustine/RituximabとBortezomib導入またはLenalidomide継続併用の3アーム無作為化第II相試験。ECOG-ACRIN E2408

A Three-Arm Randomized Phase II Study of Bendamustine/Rituximab with Bortezomib Induction or Lenalidomide Continuation in Untreated Follicular Lymphoma: ECOG-ACRIN E2408.
  • Andrew M Evens
  • Fangxin Hong
  • Thomas M Habermann
  • Ranjana H Advani
  • Randy D Gascoyne
  • Thomas E Witzig
  • Andrew Quon
  • Erik A Ranheim
  • Stephen M Ansell
  • Puneet Singh Cheema
  • Philip A Dy
  • Timothy E O'Brien
  • Jane N Winter
  • Terrence P Cescon
  • Julie E Chang
  • Brad S Kahl
  • Clin. Cancer Res..2020 Jun;1078-0432.CCR-20-1345. doi: 10.1158/1078-0432.CCR-20-1345.Epub 2020-06-12.

常染色体優性多嚢胞性腎疾患における腎予後予測における画像分類に加えて尿中アンジオテンシノーゲン

Urinary Angiotensinogen in addition to Imaging Classification in the Prediction of Renal Outcome in Autosomal Dominant Polycystic Kidney Disease.
  • Hayne Cho Park
  • Juhee Kim
  • AJin Cho
  • Do Hyoung Kim
  • Young Ki Lee
  • Hyunjin Ryu
  • Hyunsuk Kim
  • Kook Hwan Oh
  • Yun Kyu Oh
  • Young Hwan Hwang
  • Kyu Beck Lee
  • Soo Wan Kim
  • Yeong Hoon Kim
  • Joongyub Lee
  • Curie Ahn
  • J. Korean Med. Sci..2020 Jun;35(22):e165. 35.e165. doi: 10.3346/jkms.2020.35.e165.Epub 2020-06-08.

保健システムパフォーマンス評価(IPHA)への人口視点の統合。ドイツにおける横断的研究のための研究プロトコル

Integrating the Population Perspective into Health System Performance Assessment (IPHA): Study Protocol for a Cross-Sectional Study in Germany Linking Survey and Claims Data of Statutorily and Privately Insured.
  • Miriam Blümel
  • Julia Röttger
  • Julia Köppen
  • Katharina Achstetter
  • Reinhard Busse
  • Int J Health Policy Manag.2020 Jan;doi: 10.15171/ijhpm.2019.141.Epub 2020-01-20.

トレーニングによるAT受容体経路の不活性化は、高血圧ラットの高血圧前から高血圧期への移行期に自律神経制御と心臓のリモデリングを促進する

Training-Induced Deactivation of the AT Receptor Pathway Drives Autonomic Control and Heart Remodeling During the Transition From the Pre- to Hypertensive Phase in Spontaneously Hypertensive Rats.
  • Tassia Santos Rodrigues da Costa
  • Gustavo Santos Masson
  • Rosangela Aparecida Dos Santos Eichler
  • Juliane Cristina de Souza Silva
  • Silvia Lacchini
  • Lisete Compagno Michelini
  • Circ. J..2020 Jun;doi: 10.1253/circj.CJ-19-1161.Epub 2020-06-10.

複合飼料を給与した北京ダックの成長成績、枝肉形質、肉質、栄養利用率、アミノ酸の標準化された回腸消化率に及ぼす飼料タンパク質量とプロテアーゼ添加の影響

Effects of dietary protein levels and protease supplementation on growth performance, carcass traits, meat quality, and standardized ileal digestibility of amino acid in Pekin ducks fed a complex diet.
  • Q D Wang
  • K Y Zhang
  • Y Zhang
  • S P Bai
  • X M Ding
  • J P Wang
  • H W Peng
  • G Tian
  • Y Xuan
  • Z W Su
  • Q F Zeng
  • Poult. Sci..2020 Jul;99(7):3557-3566. S0032-5791(20)30223-6. doi: 10.1016/j.psj.2020.03.047.Epub 2020-04-27.

新生児臨床発作に対するレベチラセタムとフェノバルビタールの単剤治療を受けた期の乳児の神経認知転帰の比較

Comparison of the neurocognitive outcomes in term infants treated with levetiracetam and phenobarbital monotherapy for neonatal clinical seizures.
  • Pinar Arican
  • Nihal Olgac Dundar
  • Neslihan Mete Atasever
  • Mine Akkaya Inal
  • Pinar Gencpinar
  • Dilek Cavusoglu
  • Sinem Akbay
  • Hasan Tekgul
  • Seizure.2020 Jun;80:71-74. S1059-1311(20)30168-0. doi: 10.1016/j.seizure.2020.06.006.Epub 2020-06-05.

クロトニル化が重要な代謝酵素のクロトニル化を制御することで、ストレプトミセス・ロゾスポラスの炭素異化抑制が可能になることを明らかにした

Crotonylation of key metabolic enzymes regulates carbon catabolite repression in Streptomyces roseosporus.
  • Chen-Fan Sun
  • Wei-Feng Xu
  • Qing-Wei Zhao
  • Shuai Luo
  • Xin-Ai Chen
  • Yong-Quan Li
  • Xu-Ming Mao
  • Commun Biol.2020 Apr;3(1):192. 10.1038/s42003-020-0924-2. doi: 10.1038/s42003-020-0924-2.Epub 2020-04-24.

HIV-1逆転写酵素は、ツイストの活性酸素依存性アップレギュレーションを介して腫瘍の成長と転移形成を促進する

HIV-1 Reverse Transcriptase Promotes Tumor Growth and Metastasis Formation via ROS-Dependent Upregulation of Twist.
  • Ekaterina Bayurova
  • Juris Jansons
  • Dace Skrastina
  • Olga Smirnova
  • Dzeina Mezale
  • Anastasia Kostyusheva
  • Dmitry Kostyushev
  • Stefan Petkov
  • Philip Podschwadt
  • Vladimir Valuev-Elliston
  • Sviataslau Sasinovich
  • Sergey Korolev
  • Per Warholm
  • Anastasia Latanova
  • Elizaveta Starodubova
  • Amir Tukhvatulin
  • Oleg Latyshev
  • Renat Selimov
  • Pavel Metalnikov
  • Alexander Komarov
  • Olga Ivanova
  • Tatiana Gorodnicheva
  • Sergey Kochetkov
  • Marina Gottikh
  • Ilze Strumfa
  • Alexander Ivanov
  • Ilya Gordeychuk
  • Maria Isaguliants
  • Oxid Med Cell Longev.2019;2019:6016278. doi: 10.1155/2019/6016278.Epub 2019-12-02.

単細胞トランスクリプトミクスを用いた乳がんにおける骨髄由来サプレッサー細胞の出現の定義

Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics.
  • Hamad Alshetaiwi
  • Nicholas Pervolarakis
  • Laura Lynn McIntyre
  • Dennis Ma
  • Quy Nguyen
  • Jan Akara Rath
  • Kevin Nee
  • Grace Hernandez
  • Katrina Evans
  • Leona Torosian
  • Anushka Silva
  • Craig Walsh
  • Kai Kessenbrock
  • Sci Immunol.2020 02;5(44). eaay6017. doi: 10.1126/sciimmunol.aay6017.

異化分業は、工学的共培養システムにおけるグルコース-キシロース混合物からのD-乳酸およびコハク酸の生産を向上させる

Catabolic Division of Labor Enhances Production of D-Lactate and Succinate From Glucose-Xylose Mixtures in Engineered Co-culture Systems.
  • Andrew D Flores
  • Hyun G Choi
  • Rodrigo Martinez
  • Moses Onyeabor
  • E Zeynep Ayla
  • Amanda Godar
  • Michael Machas
  • David R Nielsen
  • Xuan Wang
  • Front Bioeng Biotechnol.2020;8:329. doi: 10.3389/fbioe.2020.00329.Epub 2020-05-05.

赤血球AE1/バンド3トランスポートが優性遠位性腎性尿細管アシドーシス患者に認められた

Red Blood Cell AE1/Band 3 Transports in Dominant Distal Renal Tubular Acidosis Patients.
  • Jean-Philippe Bertocchio
  • Sandrine Genetet
  • Lydie Da Costa
  • Stephen B Walsh
  • Bertrand Knebelmann
  • Julie Galimand
  • Lucie Bessenay
  • Corinne Guitton
  • Renaud De Lafaille
  • Rosa Vargas-Poussou
  • Dominique Eladari
  • Isabelle Mouro-Chanteloup
  • Kidney Int Rep.2020 Mar;5(3):348-357. S2468-0249(20)30007-3. doi: 10.1016/j.ekir.2019.12.020.Epub 2020-01-13.

2番染色体2p11.2での再発性微小欠失は、胸腺低形成とDiGeorge症候群に類似した特徴と関連している

Recurrent microdeletions at chromosome 2p11.2 are associated with thymic hypoplasia and features resembling DiGeorge syndrome.
  • Joshua D Bernstock
  • Arthur H Totten
  • Abdel G Elkahloun
  • Kory R Johnson
  • Anna C Hurst
  • Frederick Goldman
  • Andrew K Groves
  • Fady M Mikhail
  • T Prescott Atkinson
  • J. Allergy Clin. Immunol..2020 Jan;145(1):358-367.e2. S0091-6749(19)31256-4. doi: 10.1016/j.jaci.2019.09.020.Epub 2019-10-07.

高分解能質量分析法によるAverrhoa carambola L.樹皮中の二次代謝物の同定とα-グルコシダーゼ、チロシナーゼ、エラスターゼ、抗酸化力の評価

Identification of secondary metabolites in Averrhoa carambola L. bark by high-resolution mass spectrometry and evaluation for α-glucosidase, tyrosinase, elastase, and antioxidant potential.
  • Syful Islam
  • Md Badrul Alam
  • Arif Ahmed
  • Seulgidaun Lee
  • Sang-Han Lee
  • Sunghwan Kim
  • Food Chem.2020 Jun;332:127377. S0308-8146(20)31239-5. doi: 10.1016/j.foodchem.2020.127377.Epub 2020-06-23.

HIV-1サブタイプC逆転写酵素阻害のための天然物スクリーニングのためのシュードウイルスアッセイ法の開発と評価

Development of a pseudovirus assay and evaluation to screen natural products for inhibition of HIV-1 subtype C reverse transcriptase.
  • Lufuno Grace Mavhandu
  • Hua Cheng
  • Yeou-Cheng Bor
  • Denis Manga Tebit
  • Marie-Louise Hammarskjold
  • David Rekosh
  • Pascal Obong Bessong
  • J Ethnopharmacol.2020 Aug;258:112931. S0378-8741(20)30780-7. doi: 10.1016/j.jep.2020.112931.Epub 2020-04-30.

ブラジル,サンパウロの大規模総合病院における定期的なカルテ監査の評価者間の一致度をプロスペクティブに評価したもの.

A prospective evaluation of inter-rater agreement of routine medical records audits at a large general hospital in São Paulo, Brazil.
  • Ana Carolina Cintra Nunes Mafra
  • João Luiz Miraglia
  • Fernando Antonio Basile Colugnati
  • Gilberto Soares Lourenço Padilha
  • Renata Rafaella Santos Tadeucci
  • Ederson Almeida
  • Mario Maia Bracco
  • BMC Health Serv Res.2020 Jul;20(1):638. 10.1186/s12913-020-05495-w. doi: 10.1186/s12913-020-05495-w.Epub 2020-07-10.

菱形脳シナプス症、三叉神経節の突発性および視細胞腫(脱毛症を伴わない)を呈した小児:小脳三叉神経皮膚異形成症の一変か?

A child with rhombencephalosynapsis, agenesis of the trigeminal ganglion and optic coloboma (without alopecia): a variant of the cerebellotrigeminal dermal dysplasia?
  • Federica Sullo
  • Stefano Palmucci
  • Agata Polizzi
  • Martino Ruggieri
  • Andrea D Praticò
  • Clin. Dysmorphol..2020 Jul;doi: 10.1097/MCD.0000000000000333.Epub 2020-07-10.

Klf9 は、グルココルチコイド受容体活性に対するトランスクリプトーム応答を制御する重要なフィードフォワード制御因子である

Klf9 is a key feedforward regulator of the transcriptomic response to glucocorticoid receptor activity.
  • Ian Gans
  • Ellen I Hartig
  • Shusen Zhu
  • Andrea R Tilden
  • Lucie N Hutchins
  • Nathaniel J Maki
  • Joel H Graber
  • James A Coffman
  • Sci Rep.2020 Jul;10(1):11415. 10.1038/s41598-020-68040-z. doi: 10.1038/s41598-020-68040-z.Epub 2020-07-10.

QbD(Quality by Design)アプローチを用いたリバスチグミンを搭載したナノ構造脂質キャリア(NLC)の鼻から脳への送達のための二重最適化。配合変数と機器パラメータ

Double Optimization of Rivastigmine-Loaded Nanostructured Lipid Carriers (NLC) for Nose-to-Brain Delivery Using the Quality by Design (QbD) Approach: Formulation Variables and Instrumental Parameters.
  • Sara Cunha
  • Cláudia Pina Costa
  • Joana A Loureiro
  • Jorge Alves
  • Andreia F Peixoto
  • Ben Forbes
  • José Manuel Sousa Lobo
  • Ana Catarina Silva
  • Pharmaceutics.2020 Jun;12(7). E599. doi: 10.3390/pharmaceutics12070599.Epub 2020-06-28.

鉄硫黄クラスター生合成タンパク質HSCBの変異は、先天性唾液性貧血の原因となる

Mutations in the iron-sulfur cluster biogenesis protein HSCB cause congenital sideroblastic anemia.
  • Andrew Crispin
  • Chaoshe Guo
  • Caiyong Chen
  • Dean R Campagna
  • Paul J Schmidt
  • Daniel A Lichtenstein
  • Chang Cao
  • Anoop K Sendamarai
  • Gordon J Hildick-Smith
  • Nicholas C Huston
  • Jeanne Boudreaux
  • Sylvia S Bottomley
  • Matthew M Heeney
  • Barry H Paw
  • Mark D Fleming
  • Sarah Ducamp
  • J. Clin. Invest..2020 Jul;135479. doi: 10.1172/JCI135479.Epub 2020-07-07.