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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

2020年07月 みんなが読んでいる論文

切除可能な非小細胞肺癌のリンパ節転移に対する円形腫瘍DNAに基づく術前非侵襲的予測モデルの開発と検証

Development and validation of a preoperative noninvasive predictive model based on circular tumor DNA for lymph node metastasis in resectable non-small cell lung cancer.
  • Rusi Zhang
  • Xuewen Zhang
  • Zirui Huang
  • Fang Wang
  • Yongbin Lin
  • Yingsheng Wen
  • Li Liu
  • Jinbo Li
  • Xinyi Liu
  • Wenzhuan Xie
  • Mengli Huang
  • Gongming Wang
  • Longjun Yang
  • Dechang Zhao
  • Xiangyang Yu
  • Kexing Xi
  • Weidong Wang
  • Ling Cai
  • Lanjun Zhang
  • Transl Lung Cancer Res.2020 Jun;9(3):722-730. tlcr-09-03-722. doi: 10.21037/tlcr-20-593.

CR3からLFA-1受容体へのリターゲティングは、アデニル酸シクラーゼ毒素のアデニル酸シクラーゼ酵素トランスロケーションセグメントを明らかにする

Retargeting from the CR3 to the LFA-1 receptor uncovers the adenylyl cyclase enzyme-translocating segment of adenylate cyclase toxin.
  • Jiri Masin
  • Adriana Osickova
  • David Jurnecka
  • Nela Klimova
  • Humaira Khaliq
  • Peter Sebo
  • Radim Osicka
  • J. Biol. Chem..2020 Jul;295(28):9349-9365. RA120.013630. doi: 10.1074/jbc.RA120.013630.Epub 2020-05-11.

種の分布モデリングにおける社会経済の利用。農村社会の特徴は、フクロウの発生予測を向上させる

The use of socio-economy in species distribution modelling: Features of rural societies improve predictions of barn owl occurrence.
  • Michał Żmihorski
  • Marek Kowalski
  • Jan Cichocki
  • Sławomir Rubacha
  • Dorota Kotowska
  • Dominik Krupiński
  • Zuzanna M Rosin
  • Martin Šálek
  • Tomas Pärt
  • Sci. Total Environ..2020 Jun;741:140407. S0048-9697(20)33929-2. doi: 10.1016/j.scitotenv.2020.140407.Epub 2020-06-20.

不妊症女性の膣マイクロバイオームの特徴と受精手術中のホルモン刺激との関連性

Characterization of the Vaginal Microbiome in Women with Infertility and Its Potential Correlation with Hormone Stimulation during Fertilization Surgery.
  • Changying Zhao
  • Zefeng Wei
  • Junjie Yang
  • Jiaming Zhang
  • Chunna Yu
  • Aijun Yang
  • Min Zhang
  • Lin Zhang
  • Ye Wang
  • Xiaofeng Mu
  • Xueyuan Heng
  • Huijun Yang
  • Zhongtao Gai
  • Xuenan Wang
  • Lei Zhang
  • mSystems.2020 Jul;5(4). e00450-20. doi: 10.1128/mSystems.00450-20.Epub 2020-07-14.

ヒトアポリポ蛋白質の大規模プロファイリングのためのハイスループット質量分析ベースのアッセイ

A high-throughput mass spectrometry-based assay for large-scale profiling of circulating human apolipoproteins.
  • Valentin Blanchard
  • Damien Garçon
  • Catherine Jaunet
  • Kevin Chemello
  • Stéphanie Billon-Crossouard
  • Audrey Aguesse
  • Aya Garfa
  • Gilles Famchon
  • Amada Torres
  • Cédric Le May
  • Matthieu Pichelin
  • Edith Bigot-Corbel
  • Gilles Lambert
  • Bertrand Cariou
  • Samy Hadjadj
  • Michel Krempf
  • Kalyane Bach-Ngohou
  • Mikaël Croyal
  • J. Lipid Res..2020 Jul;61(7):1128-1139. jlr.D120000835. doi: 10.1194/jlr.D120000835.Epub 2020-05-13.

細菌性エンドトキシンはガスデルミンD依存性ホスファチジルセリン暴露を介して凝固カスケードを活性化する.

Bacterial Endotoxin Activates the Coagulation Cascade through Gasdermin D-Dependent Phosphatidylserine Exposure.
  • Xinyu Yang
  • Xiaoye Cheng
  • Yiting Tang
  • Xianhui Qiu
  • Yupeng Wang
  • Haixia Kang
  • Jianfeng Wu
  • Zhongtai Wang
  • Yukun Liu
  • Fangping Chen
  • Xianzhong Xiao
  • Nigel Mackman
  • Timothy R Billiar
  • Jiahuai Han
  • Ben Lu
  • Immunity.2019 12;51(6):983-996.e6. S1074-7613(19)30463-7. doi: 10.1016/j.immuni.2019.11.005.Epub 2019-12-10.

タキシフォリンはニワトリ心筋細胞のチトクロームP450の恒常性を介してDEHP曝露によるアポトーシス障害を緩和する

Taxifolin alleviates apoptotic injury induced by DEHP exposure through cytochrome P450 homeostasis in chicken cardiomyocytes.
  • Yuan Zhang
  • Guangliang Shi
  • Jingzeng Cai
  • Jie Yang
  • Yingying Zheng
  • Dahai Yu
  • Qi Liu
  • Yafan Gong
  • Ziwei Zhang
  • Ecotoxicol. Environ. Saf..2019 Nov;183:109582. S0147-6513(19)30913-3. doi: 10.1016/j.ecoenv.2019.109582.Epub 2019-08-20.

侵略的外来種に対する科学者の警告

Scientists' warning on invasive alien species.
  • Petr Pyšek
  • Philip E Hulme
  • Dan Simberloff
  • Sven Bacher
  • Tim M Blackburn
  • James T Carlton
  • Wayne Dawson
  • Franz Essl
  • Llewellyn C Foxcroft
  • Piero Genovesi
  • Jonathan M Jeschke
  • Ingolf Kühn
  • Andrew M Liebhold
  • Nicholas E Mandrak
  • Laura A Meyerson
  • Aníbal Pauchard
  • Jan Pergl
  • Helen E Roy
  • Hanno Seebens
  • Mark van Kleunen
  • Montserrat Vilà
  • Michael J Wingfield
  • David M Richardson
  • Biol Rev Camb Philos Soc.2020 Jun;doi: 10.1111/brv.12627.Epub 2020-06-25.

二次元・三次元超音波を用いた大型エピグナス型奇形腫の出生前診断:病理所見との相関.

Prenatal diagnosis of a large epignathus teratoma using two-dimensional and three-dimensional ultrasound: correlation with pathological findings.
  • Maira Mariko Takagi
  • Luiz Claudio Silva Bussamra
  • E Araujo Júnior
  • Carolina Leite Drummond
  • Sandra Regina Silva Herbst
  • Luciano Marcondes Machado Nardozza
  • Antonio Fernandes Moron
  • José Mendes Aldrighi
  • Cleft Palate Craniofac. J..2014 May;51(3):350-3. doi: 10.1597/12-222.Epub 2013-02-11.

外科的に切除された非小細胞肺癌における予後を左右するラジオ免疫シグネチャーの同定に関するデータセット

Dataset on the identification of a prognostic radio-immune signature in surgically resected Non Small Cell Lung Cancer.
  • Giulia Mazzaschi
  • Gianluca Milanese
  • Paolo Pagano
  • Denise Madeddu
  • Letizia Gnetti
  • Francesca Trentini
  • Angela Falco
  • Caterina Frati
  • Bruno Lorusso
  • Costanza Lagrasta
  • Roberta Minari
  • Luca Ampollini
  • Mario Silva
  • Nicola Sverzellati
  • Federico Quaini
  • Giovanni Roti
  • Marcello Tiseo
  • Data Brief.2020 Aug;31:105781. S2352-3409(20)30675-2. doi: 10.1016/j.dib.2020.105781.Epub 2020-06-02.

多形性神経膠芽腫。質量分析イメージングにより明らかになった胸膜周囲組織およびIDH変異グリオーマとの代謝的差異

Glioblastoma multiforme: Metabolic differences to peritumoral tissue and IDH-mutated gliomas revealed by mass spectrometry imaging.
  • Judith M Kampa
  • Udo Kellner
  • Christian Marsching
  • Carina Ramallo Guevara
  • Ulrich J Knappe
  • Mikail Sahin
  • Marco Giampà
  • Karsten Niehaus
  • Hanna Bednarz
  • Neuropathology.2020 Jul;doi: 10.1111/neup.12671.Epub 2020-07-13.

コートジボワール西部での持続的なスキストソーマ・マンソニのホットスポットの特徴

Characteristics of persistent hotspots of Schistosoma mansoni in western Côte d'Ivoire.
  • Rufin K Assaré
  • Roméo N N'Tamon
  • Louise G Bellai
  • Judicaelle A Koffi
  • Tra-Bi I Mathieu
  • Mamadou Ouattara
  • Eveline Hürlimann
  • Jean T Coulibaly
  • Salia Diabaté
  • Eliézer K N'Goran
  • Jürg Utzinger
  • Parasit Vectors.2020 Jul;13(1):337. 10.1186/s13071-020-04188-x. doi: 10.1186/s13071-020-04188-x.Epub 2020-07-02.

4-メチルウンベリフェロンの抗増殖効果は、細胞内恒常性の破壊とPI3K/AKTおよびMAPKシグナル伝達の制御によって媒介されている

Antiproliferative Effect of 4-Methylumbelliferone in Epithelial Ovarian Cancer Cells Is Mediated by Disruption of Intracellular Homeostasis and Regulation of PI3K/AKT and MAPK Signaling.
  • Garam An
  • Sunwoo Park
  • Minkyoung Lee
  • Whasun Lim
  • Gwonhwa Song
  • Pharmaceutics.2020 Jul;12(7). E640. doi: 10.3390/pharmaceutics12070640.Epub 2020-07-07.

グリコーゲン合成酵素キナーゼ-3βは、12-O-テトラデカノイルフェノール-13-アセテート/イオノマイシン活性化ヒトCD4 Tリンパ球におけるサイトカイン産生を促進する

Glycogen Synthase Kinase-3β Facilitates Cytokine Production in 12-O-Tetradecanoylphorbol-13-Acetate/Ionomycin-Activated Human CD4 T Lymphocytes.
  • Cheng-Chieh Tsai
  • Chin-Kun Tsai
  • Po-Chun Tseng
  • Chiou-Feng Lin
  • Chia-Ling Chen
  • Cells.2020 Jun;9(6). E1424. doi: 10.3390/cells9061424.Epub 2020-06-08.

比較ゲノム解析により、臨床エリザベスキンキア髄膜敗血症における多様な病原性因子と抗菌薬耐性機構を明らかにした

Comparative genomic analyses reveal diverse virulence factors and antimicrobial resistance mechanisms in clinical Elizabethkingia meningoseptica strains.
  • Shicheng Chen
  • Marty Soehnlen
  • Jochen Blom
  • Nicolas Terrapon
  • Bernard Henrissat
  • Edward D Walker
  • PLoS ONE.2019;14(10):e0222648. PONE-D-19-17060. doi: 10.1371/journal.pone.0222648.Epub 2019-10-10.

パーキンソン病タンパク質LRRK2はGARP複合体と相互作用してゴルジ網への逆行輸送を促進する

The Parkinson's Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network.
  • Alexandra Beilina
  • Luis Bonet-Ponce
  • Ravindran Kumaran
  • Jennifer J Kordich
  • Morié Ishida
  • Adamantios Mamais
  • Alice Kaganovich
  • Sara Saez-Atienzar
  • David C Gershlick
  • Dorien A Roosen
  • Laura Pellegrini
  • Vlad Malkov
  • Matthew J Fell
  • Kirsten Harvey
  • Juan S Bonifacino
  • Darren J Moore
  • Mark R Cookson
  • Cell Rep.2020 May;31(5):107614. S2211-1247(20)30563-5. doi: 10.1016/j.celrep.2020.107614.

バレット食道および食道腺癌の機能的関連遺伝子座の同定:疾患関連組織からの発現定量形質遺伝子座データと遺伝学的関連データとのクロスリファレンス

Identification of loci of functional relevance to Barrett's esophagus and esophageal adenocarcinoma: Cross-referencing of expression quantitative trait loci data from disease-relevant tissues with genetic association data.
  • Julia Schröder
  • Vitalia Schüller
  • Andrea May
  • Christian Gerges
  • Mario Anders
  • Jessica Becker
  • Timo Hess
  • Nicole Kreuser
  • René Thieme
  • Kerstin U Ludwig
  • Tania Noder
  • Marino Venerito
  • Lothar Veits
  • Thomas Schmidt
  • Claudia Fuchs
  • Jakob R Izbicki
  • Arnulf H Hölscher
  • Dani Dakkak
  • Boris Jansen-Winkeln
  • Yusef Moulla
  • Orestis Lyros
  • Stefan Niebisch
  • Matthias Mehdorn
  • Hauke Lang
  • Dietmar Lorenz
  • Brigitte Schumacher
  • Rupert Mayershofer
  • Yogesh Vashist
  • Katja Ott
  • Michael Vieth
  • Josef Weismüller
  • Elisabeth Mangold
  • Markus M Nöthen
  • Susanne Moebus
  • Michael Knapp
  • Horst Neuhaus
  • Thomas Rösch
  • Christian Ell
  • Ines Gockel
  • Johannes Schumacher
  • Anne C Böhmer
  • PLoS ONE.2019;14(12):e0227072. PONE-D-19-25430. doi: 10.1371/journal.pone.0227072.Epub 2019-12-31.

BMP、FGF、RAシグナル伝達経路の複合的な調節によるヒト人工多能性幹細胞の産婦人科リンパ節様細胞への濃縮分化の研究

Enrichment differentiation of human induced pluripotent stem cells into sinoatrial node-like cells by combined modulation of BMP, FGF, and RA signaling pathways.
  • Feng Liu
  • Yibing Fang
  • Xiaojie Hou
  • Ying Yan
  • Haiying Xiao
  • Dongchuan Zuo
  • Jing Wen
  • Linli Wang
  • Zhichao Zhou
  • Xitong Dang
  • Rui Zhou
  • Bin Liao
  • Stem Cell Res Ther.2020 Jul;11(1):284. 10.1186/s13287-020-01794-5. doi: 10.1186/s13287-020-01794-5.Epub 2020-07-16.

カテプシンAはマウスの細胞外スーパーオキシドジスムターゼを分解することで左室リモデリングに寄与している

Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice.
  • Mathias Hohl
  • Manuel Mayr
  • Lisa Lang
  • Alexander G Nickel
  • Javier Barallobre Barreiro
  • Xiaoke Yin
  • Thimoteus Speer
  • Simina Ramona Selejan
  • Claudia Goettsch
  • Katharina Erb
  • Claudia Fecher-Trost
  • Jan-Christian Reil
  • Benedikt Linz
  • Sven Ruf
  • Thomas Hübschle
  • Christoph Maack
  • Michael Böhm
  • Thorsten Sadowski
  • Dominik Linz
  • J. Biol. Chem..2020 Jul;jbc.RA120.013488. doi: 10.1074/jbc.RA120.013488.Epub 2020-07-09.

甜菜嚢線虫のトランスクリプトーム配列から得られた新規ピコルナウイルス様ゲノムは、新属を代表するものである

A novel picornavirus-like genome from transcriptome sequencing of sugar beet cyst nematode represents a new putative genus.
  • Jingyu Lin
  • Rongjian Ye
  • Thanuja Thekke-Veetil
  • Margaret E Staton
  • Prakash R Arelli
  • Ernest C Bernard
  • Tarek Hewezi
  • Leslie L Domier
  • M R Hajimorad
  • J. Gen. Virol..2018 10;99(10):1418-1424. doi: 10.1099/jgv.0.001139.Epub 2018-08-29.

ブルガリア産イヌラ6種のカフェオレフィン酸、細胞毒性、抗酸化作用、アセチルコリンエステラーゼおよびチロシナーゼ酵素阻害活性

Caffeoylquinic Acids, Cytotoxic, Antioxidant, Acetylcholinesterase and Tyrosinase Enzyme Inhibitory Activities of Six Inula Species from Bulgaria.
  • Antoaneta Trendafilova
  • Victoria Ivanova
  • Miroslav Rangelov
  • Milka Todorova
  • Gulmira Ozek
  • Suleyman Yur
  • Temel Ozek
  • Ina Aneva
  • Ralitza Veleva
  • Veselina Moskova-Doumanova
  • Jordan Doumanov
  • Tanya Topouzova-Hristova
  • Chem. Biodivers..2020 Apr;17(4):e2000051. doi: 10.1002/cbdv.202000051.Epub 2020-03-18.

ガーナ人集団における抗レトロウイルス感染HIV患者における一塩基多型と脂質異常症との関連。ケースコントロール研究

Association of single nucleotide polymorphisms with dyslipidemia in antiretroviral exposed HIV patients in a Ghanaian population: A case-control study.
  • Christian Obirikorang
  • Emmanuel Acheampong
  • Lawrence Quaye
  • Joseph Yorke
  • Ernestine Kubi Amos-Abanyie
  • Priscilla Abena Akyaw
  • Enoch Odame Anto
  • Simon Bannison Bani
  • Evans Adu Asamoah
  • Emmanuella Nsenbah Batu
  • PLoS ONE.2020;15(1):e0227779. PONE-D-19-22071. doi: 10.1371/journal.pone.0227779.Epub 2020-01-13.

選択的で経口的に生物学的に利用可能な第XIa因子阻害剤の構造に基づく設計と前臨床特性の評価S1プロテアーゼファミリーの統合的アプローチの威力を実証

Structure-based design and pre-clinical characterization of selective and orally bioavailable Factor XIa inhibitors: Demonstrating the power of an integrated S1 protease family approach.
  • Edwige Lorthiois
  • James Roache
  • David Barnes-Seeman
  • Eva Altmann
  • Ulrich Hassiepen
  • Gordon Turner
  • Rohit Duvadie
  • Viktor Hornak
  • Rajeshri G Karki
  • Nikolaus Schiering
  • Wilhelm A Weihofen
  • Francesca Perruccio
  • Amy Calhoun
  • Tanzina Fazal
  • Darija Dedic
  • Corinne Durand
  • Solene Dussauge
  • Kamal Fettis
  • Fabien Tritsch
  • Celine Dentel
  • Adelaide Druet
  • Donglei Liu
  • Louise Kirman
  • Julie Lachal
  • Kenji Namoto
  • Douglas Bevan
  • Rose Mo
  • Gabriela Monnet
  • Lionel Muller
  • Richard Zessis
  • Xueming Huang
  • Loren Lindsley
  • Treeve Currie
  • Yu-Hsin Chiu
  • Cary Fridrich
  • Peter Delgado
  • Shuangxi Wang
  • Micah Hollis-Symynkywicz
  • Joerg Berghausen
  • Eric Williams
  • Hong Liu
  • Guiqing Liang
  • Hyungchul Kim
  • Peter Hoffmann
  • Andreas Hein
  • Paul Ramage
  • Allan D'Arcy
  • Stefanie Harlfinger
  • Martin Renatus
  • Simon Ruedisser
  • David Feldman
  • Jason Elliott
  • Richard C Sedrani
  • Jürgen Maibaum
  • Christopher M Adams
  • J. Med. Chem..2020 Jun;doi: 10.1021/acs.jmedchem.0c00279.Epub 2020-06-17.

ブラジルのマリアナ州(MG)の災害からの鉱滓は、キビ、トウモロコシ、ソルガムの初期発生に影響を与えるか?

Do tailings from the Mariana, MG (Brazil), disaster affect the initial development of millet, maize, and sorghum?
  • Gisele de Fátima Esteves
  • Leticia Aparecida Bressanin
  • Kamila Rezende Dázio de Souza
  • Adriano Bortolotti da Silva
  • José Ricardo Mantovani
  • Daniele Maria Marques
  • Paulo César Magalhães
  • Moacir Pasqual
  • Thiago Corrêa de Souza
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-10013-w. doi: 10.1007/s11356-020-10013-w.Epub 2020-07-06.