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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

2020年07月 みんなが読んでいる論文

グローバル髄膜炎ゲノムパートナーシップ

The global meningitis genome partnership.
  • Elizabeth Rodgers
  • Stephen D Bentley
  • Ray Borrow
  • Holly B Bratcher
  • Sylvain Brisse
  • Angela B Brueggemann
  • Dominique A Caugant
  • Jamie Findlow
  • LeAnne Fox
  • Linda Glennie
  • Lee H Harrison
  • Odile B Harrison
  • Robert S Heyderman
  • Melissa Jansen van Rensburg
  • Keith A Jolley
  • Brenda Kwambana-Adams
  • Shamez Ladhani
  • Marc LaForce
  • Michael Levin
  • Jay Lucidarme
  • Neil MacAlasdair
  • Jenny Maclennan
  • Martin C J Maiden
  • Laura Maynard-Smith
  • Alessandro Muzzi
  • Philipp Oster
  • Charlene M C Rodrigues
  • Olivier Ronveaux
  • Laura Serino
  • Vinny Smith
  • Arie van der Ende
  • Julio Vázquez
  • Xin Wang
  • Saber Yezli
  • James M Stuart
  • J. Infect..2020 Jun;S0163-4453(20)30446-1. doi: 10.1016/j.jinf.2020.06.064.Epub 2020-06-29.

cusatuzumabでCD70を標的とすることで、低メチル化剤で治療された患者の急性骨髄性白血病幹細胞が排除される

Targeting CD70 with cusatuzumab eliminates acute myeloid leukemia stem cells in patients treated with hypomethylating agents.
  • Carsten Riether
  • Thomas Pabst
  • Sabine Höpner
  • Ulrike Bacher
  • Magdalena Hinterbrandner
  • Yara Banz
  • Rouven Müller
  • Markus G Manz
  • Walid H Gharib
  • David Francisco
  • Remy Bruggmann
  • Luc van Rompaey
  • Mahan Moshir
  • Tim Delahaye
  • Domenica Gandini
  • Ellen Erzeel
  • Anna Hultberg
  • Samson Fung
  • Hans de Haard
  • Nicolas Leupin
  • Adrian F Ochsenbein
  • Nat. Med..2020 Jun;10.1038/s41591-020-0910-8. doi: 10.1038/s41591-020-0910-8.Epub 2020-06-29.

HIV-1 自然感染および RV114 ワクチン試験における Fc 媒介応答に関与する C1/C2 エピトープの認識パターン

Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial.
  • William D Tolbert
  • Verna Van
  • Rebekah Sherburn
  • Marina Tuyishime
  • Fang Yan
  • Dung N Nguyen
  • Sherry Stanfield-Oakley
  • David Easterhoff
  • Mattia Bonsignori
  • Barton F Haynes
  • M Anthony Moody
  • Krishanu Ray
  • Guido Ferrari
  • George K Lewis
  • Marzena Pazgier
  • mBio.2020 Jun;11(3). e00208-20. doi: 10.1128/mBio.00208-20.Epub 2020-06-30.

繊毛化ヒト鼻上皮細胞における細胞内Clによって制御された繊毛拍動振幅と高率のCO産生

Ciliary beating amplitude controlled by intracellular Cl and a high rate of CO production in ciliated human nasal epithelial cells.
  • Taka-Aki Inui
  • Kentaro Murakami
  • Makoto Yasuda
  • Shigeru Hirano
  • Yukiko Ikeuchi
  • Haruka Kogiso
  • Shigekuni Hosogi
  • Toshio Inui
  • Yoshinori Marunaka
  • Takashi Nakahari
  • Pflugers Arch..2019 08;471(8):1127-1142. 10.1007/s00424-019-02280-5. doi: 10.1007/s00424-019-02280-5.Epub 2019-05-18.

オリーブのバイオマスをベースにした高表面積活性炭へのアモキシシリンの吸着:速度論的・平衡論的研究

Adsorption of amoxicillin onto high surface area-activated carbons based on olive biomass: kinetic and equilibrium studies.
  • Daniel Lucas Costa Rodrigues
  • Fernando Machado Machado
  • Alice Gonçalves Osório
  • Cristiane Ferraz de Azevedo
  • Eder Claudio Lima
  • Raphaelle S da Silva
  • Diana Ramos Lima
  • Fernanda Medeiros Gonçalves
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-09583-6. doi: 10.1007/s11356-020-09583-6.Epub 2020-07-18.

インドネシアの蚊から分離された蚊媒介ウイルス、昆虫特異的フラビウイルス(フラビウイルス科、フラビウイルス属)、Bannaウイルス(Reoviridae科、Seadornavirus属)、Bogorウイルス(Permutotetraviridae科の未分類メンバー)、およびalphamesoniviruses 2および3(Mesoniviridae科、Alphamesonivirus属)を用いて、蚊が媒介するウイルスを調査した

Mosquito-borne viruses, insect-specific flaviviruses (family Flaviviridae, genus Flavivirus), Banna virus (family Reoviridae, genus Seadornavirus), Bogor virus (unassigned member of family Permutotetraviridae), and alphamesoniviruses 2 and 3 (family Mesoniviridae, genus Alphamesonivirus) isolated from Indonesian mosquitoes.
  • Ryusei Kuwata
  • Shun Torii
  • Hiroshi Shimoda
  • Keita Ishijima
  • Kenzo Yonemitsu
  • Shohei Minami
  • Yudai Kuroda
  • Kango Tatemoto
  • Ngo Thuy Bao Tran
  • Ai Takano
  • Tsutomu Omatsu
  • Tetsuya Mizutani
  • Kentaro Itokawa
  • Haruhiko Isawa
  • Kyoko Sawabe
  • Tomohiko Takasaki
  • Dewi Maria Yuliani
  • Dimas Abiyoga
  • Upik Kesumawati Hadi
  • Agus Setiyono
  • Eiichi Hondo
  • Srihadi Agungpriyono
  • Ken Maeda
  • J. Vet. Med. Sci..2020 May;doi: 10.1292/jvms.20-0261.Epub 2020-05-25.

ニコチンは若年成人ラットのマイトファジークリアランスを阻害することで心毒性を誘導する

Nicotine induces cardiac toxicity through blocking mitophagic clearance in young adult rat.
  • Guizhi Jia
  • Zhijun Meng
  • Caihong Liu
  • Xinliang Ma
  • Jia Gao
  • Jing Liu
  • Rui Guo
  • Zheyi Yan
  • Theodore Christopher
  • Bernard Lopez
  • Wenxia Liu
  • Hongliang Dai
  • Wayne Bond Lau
  • Xiangying Jiao
  • Jianli Zhao
  • Zi-Xuan Wang
  • Jimin Cao
  • Yajing Wang
  • Life Sci..2020 Jul;:118084. S0024-3205(20)30835-3. doi: 10.1016/j.lfs.2020.118084.Epub 2020-07-11.

治療的中絶と子宮外妊娠:イスラム国イランにおける胎児幹細胞研究と治療の代替ソース

Therapeutic abortion and ectopic pregnancy: alternative sources for fetal stem cell research and therapy in Iran as an Islamic country.
  • Parisa Goodarzi
  • Khadijeh Falahzadeh
  • Hamidreza Aghayan
  • Moloud Payab
  • Bagher Larijani
  • Sepideh Alavi-Moghadam
  • Akram Tayanloo-Beik
  • Hossein Adibi
  • Kambiz Gilany
  • Babak Arjmand
  • Cell Tissue Bank.2019 Mar;20(1):11-24. 10.1007/s10561-018-9741-y. doi: 10.1007/s10561-018-9741-y.Epub 2018-12-07.

黄色ブドウ球菌バイオフィルムによる乳酸産生は、持続感染時に宿主免疫応答を再プログラムするHDAC11を阻害する

Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection.
  • Cortney E Heim
  • Megan E Bosch
  • Kelsey J Yamada
  • Amy L Aldrich
  • Sujata S Chaudhari
  • David Klinkebiel
  • Casey M Gries
  • Abdulelah A Alqarzaee
  • Yixuan Li
  • Vinai C Thomas
  • Edward Seto
  • Adam R Karpf
  • Tammy Kielian
  • Nat Microbiol.2020 Jul;10.1038/s41564-020-0756-3. doi: 10.1038/s41564-020-0756-3.Epub 2020-07-13.

その結果、三酸化ヒ素と BIBR1532 は、NF-κB シグナル伝達経路の減衰を介して乳がん細胞の増殖を相乗的に抑制することが確認されました

Arsenic trioxide and BIBR1532 synergistically inhibit breast cancer cell proliferation through attenuation of NF-κB signaling pathway.
  • Ali Nasrollahzadeh
  • Davood Bashash
  • Majid Kabuli
  • Zahra Zandi
  • Bahahreh Kashani
  • Azam Zaghal
  • Seyed A Mousavi
  • Seyed H Ghaffari
  • Life Sci..2020 Jul;:118060. S0024-3205(20)30811-0. doi: 10.1016/j.lfs.2020.118060.Epub 2020-07-06.

ビフェントリンとアセトクロルの二種類の組み合わせに曝露した胚-幼体ゼブラフィッシュにおける甲状腺ホルモンレベルと関連遺伝子発現の変化

Changes in thyroid hormone levels and related gene expressions in embryo-larval zebrafish exposed to binary combinations of bifenthrin and acetochlor.
  • Dongmei Guo
  • Wenping Liu
  • Jing Qiu
  • Yun Li
  • Liezong Chen
  • Shenggan Wu
  • Qiang Wang
  • Yongzhong Qian
  • Ecotoxicology.2020 Jul;29(5):584-593. 10.1007/s10646-020-02206-3. doi: 10.1007/s10646-020-02206-3.Epub 2020-05-28.

高麗紅参は、エストロゲン受容体βや脳由来の神経栄養因子のアップレギュレーションを介して酸化ストレスを抑制することで、間欠的な熱ストレスを受けたラット脳の神経炎症を緩和し、細胞の生存を促進します

Korean Red Ginseng alleviates neuroinflammation and promotes cell survival in the intermittent heat stress-induced rat brain by suppressing oxidative stress via estrogen receptor beta and brain-derived neurotrophic factor upregulation.
  • Hamid Iqbal
  • Si-Kwan Kim
  • Kyu-Min Cha
  • Min-Sik Jeong
  • Prachetash Ghosh
  • Dong-Kwon Rhee
  • J Ginseng Res.2020 Jul;44(4):593-602. S1226-8453(19)30012-0. doi: 10.1016/j.jgr.2019.05.007.Epub 2019-05-24.

低酸素およびミトコンドリア呼吸阻害剤によるスクイコチリエート寄生虫のオルタナティブオキシダーゼの分子特性と遺伝子発現の調節

Molecular characterization and gene expression modulation of the alternative oxidase in a scuticociliate parasite by hypoxia and mitochondrial respiration inhibitors.
  • Iría Folgueira
  • Jesús Lamas
  • Rosa Ana Sueiro
  • José Manuel Leiro
  • Sci Rep.2020 Jul;10(1):11880. 10.1038/s41598-020-68791-9. doi: 10.1038/s41598-020-68791-9.Epub 2020-07-17.

妊娠初期に子豚にアルギニンを補給すると、豚のコンセプテーゼのエネルギー感受性経路に影響を与えます

l-Arginine supplementation of gilts during early gestation modulates energy sensitive pathways in pig conceptuses.
  • Ingrid S Garcia
  • Susana A Teixeira
  • Karine A Costa
  • Daniele B D Marques
  • Gustavo de A Rodrigues
  • Thaís C Costa
  • José D Guimarães
  • Pamela I Otto
  • Alysson Saraiva
  • Adriana M G Ibelli
  • Maurício E Cantão
  • Haniel C de Oliveira
  • Mônica C Ledur
  • Jane de O Peixoto
  • Simone E F Guimarães
  • Mol. Reprod. Dev..2020 Jun;doi: 10.1002/mrd.23397.Epub 2020-06-27.

抗レトロウイルス管理のためのミトコンドリアトキシコゲノミクス。未感染患者におけるHIV曝露後の予防

Mitochondrial Toxicogenomics for Antiretroviral Management: HIV Post-exposure Prophylaxis in Uninfected Patients.
  • Maria Bañó
  • Constanza Morén
  • Sergio Barroso
  • Diana Luz Juárez
  • Mariona Guitart-Mampel
  • Ingrid González-Casacuberta
  • Judith Canto-Santos
  • Ester Lozano
  • Agathe León
  • Enric Pedrol
  • Òscar Miró
  • Ester Tobías
  • Josep Mallolas
  • Jhon F Rojas
  • Francesc Cardellach
  • Esteban Martínez
  • Gloria Garrabou
  • Front Genet.2020;11:497. doi: 10.3389/fgene.2020.00497.Epub 2020-05-26.

ピペリンアルカロイドは、G2/M期の細胞周期停止、カスパーゼ活性化、細胞遊走阻害、PI3K/Akt/GSK3βシグナル伝達経路の阻害により、シスプラチン抵抗性卵巣癌において抗癌作用、アポトーシス作用を誘導する

Piperine alkaloid induces anticancer and apoptotic effects in cisplatin resistant ovarian carcinoma by inducing G2/M phase cell cycle arrest, caspase activation and inhibition of cell migration and PI3K/Akt/GSK3β signalling pathway.
  • Min Qiu
  • Chunyan Xue
  • Lingyan Zhang
  • J BUON.2019 Nov-Dec;24(6):2316-2321.

コイ医科大学の学生における月経前症候群の酸化ストレスマーカーに及ぼすベンソン・リラクセーションの影響

The Influence of Benson Relaxation on Oxidative Stress Marker of Premenstrual Syndrome in Students of Khoy University of Medical Sciences.
  • Jalhe Bagheri Hamzyan Olia
  • Soryya Zinalpoor
  • Shahriar Sakhaei
  • Hassan Ebrahimpour Sadagheyani
  • Hossein Motaarefi
  • Open Access Maced J Med Sci.2019 Dec;7(23):4149-4154. OAMJMS-7-4149. doi: 10.3889/oamjms.2019.865.Epub 2019-12-10.

成人における在宅経腸栄養-全国多施設調査.

Home Enteral Nutrition in Adults-Nationwide Multicenter Survey.
  • Marcin Folwarski
  • Stanisław Kłęk
  • Agata Zoubek-Wójcik
  • Waldemar Szafrański
  • Lidia Bartoszewska
  • Krzysztof Figuła
  • Marlena Jakubczyk
  • Anna Jurczuk
  • Zbigniew Kamocki
  • Karolina Kaźmierczak-Siedlecka
  • Tomasz Kowalczyk
  • Bogna Kwella
  • Przemysław Matras
  • Karolina Skonieczna-Żydecka
  • Joanna Sonsala-Wołczyk
  • Jacek Szopiński
  • Krystyna Urbanowicz
  • Anna Zmarzły
  • Nutrients.2020 Jul;12(7). E2087. doi: 10.3390/nu12072087.Epub 2020-07-14.

ロッド特異的なDHDDSアブレーションによって引き起こされる網膜変性は、タンパク質のN-グリコシル化の同時阻害なしに発生します

Retinal Degeneration Caused by Rod-Specific Dhdds Ablation Occurs without Concomitant Inhibition of Protein N-Glycosylation.
  • Sriganesh Ramachandra Rao
  • Lara A Skelton
  • Fuguo Wu
  • Agnieszka Onysk
  • Grzegorz Spolnik
  • Witold Danikiewicz
  • Mark C Butler
  • Delores A Stacks
  • Liliana Surmacz
  • Xiuqian Mu
  • Ewa Swiezewska
  • Steven J Pittler
  • Steven J Fliesler
  • iScience.2020 Jun;23(6):101198. S2589-0042(20)30383-7. doi: 10.1016/j.isci.2020.101198.Epub 2020-05-23.

次亜塩素酸カルシウムの過酢酸と活性塩素の致死濃度と亜致死濃度の影響

Effects of lethal and sublethal concentrations of peracetic acid and active chlorine of calcium hypochlorite on Chironomus xanthus.
  • Luana Priscilla Rodrigues Macêdo
  • Aline Silvestre Pereira Dornelas
  • Mayane Marques Vieira
  • Joel Santiago de Jesus Ferreira
  • Renato Almeida Sarmento
  • Grasiele Soares Cavallini
  • Chemosphere.2020 Oct;256:127171. S0045-6535(20)31364-3. doi: 10.1016/j.chemosphere.2020.127171.Epub 2020-05-23.

下顎切開管の有病率と形態.コーンビームコンピュータ断層撮影を用いた北京地区の人口における健康な大あご、歯周炎、無歯顎の比較

Prevalence and Morphology of Mandibular Incisive Canal: Comparison among Healthy, Periodontitis and Edentulous Mandibles in a Population of the Beijing Area Using Cone-beam Computed Tomography.
  • Ya Qiong Zhang
  • Xue Bing Yan
  • Li Qi Zhang
  • Xiao Yan Xie
  • Deng Gao Liu
  • Zu Yan Zhang
  • Chin J Dent Res.2019;22(4):241-249. 43735. doi: 10.3290/j.cjdr.a43735.

トウモロコシワラとキャベツ廃棄物の共エンサイリングシステムの発酵特性と微生物群集の多様性に及ぼす季節温度の違いの影響

Effects of different simulated seasonal temperatures on the fermentation characteristics and microbial community diversities of the maize straw and cabbage waste co-ensiling system.
  • Haiwei Ren
  • Yinping Feng
  • Tong Liu
  • Jinping Li
  • Zhiye Wang
  • Shanfei Fu
  • Yi Zheng
  • Zhangpu Peng
  • Sci. Total Environ..2020 Mar;708:135113. S0048-9697(19)35105-8. doi: 10.1016/j.scitotenv.2019.135113.Epub 2019-11-22.

腎移植患者におけるファーマコゲノミクスと実践への統合の可能性

Pharmacogenomics in kidney transplant recipients and potential for integration into practice.
  • Tam T Nguyen
  • Rachael A Pearson
  • Moataz E Mohamed
  • David P Schladt
  • Danielle Berglund
  • Zachary Rivers
  • Debra J Skaar
  • Baolin Wu
  • Weihua Guan
  • Jessica van Setten
  • Brendan J Keating
  • Casey Dorr
  • Rory P Remmel
  • Arthur J Matas
  • Roslyn B Mannon
  • Ajay K Israni
  • William S Oetting
  • Pamala A Jacobson
  • J Clin Pharm Ther.2020 Jul;doi: 10.1111/jcpt.13223.Epub 2020-07-14.

同一環境下で飼育された寄生虫の子鳥と宿主の子鳥の腸内細菌叢:遺伝的影響と環境的影響の切り分け

The gut microbiota of brood parasite and host nestlings reared within the same environment: disentangling genetic and environmental effects.
  • Chop Yan Lee
  • Juan Manuel Peralta-Sánchez
  • Manuel Martínez-Bueno
  • Anders Pape Møller
  • Miguel Rabelo-Ruiz
  • Carmen Zamora-Muñoz
  • Juan José Soler
  • ISME J.2020 Jul;10.1038/s41396-020-0719-y. doi: 10.1038/s41396-020-0719-y.Epub 2020-07-17.

ケタミンの持続的な抗うつ活性には、皮質およびラッパのGABA、AMPA受容体およびグリアGLT-1グルタミン酸トランスポーターが寄与しています

Cortical and raphe GABA, AMPA receptors and glial GLT-1 glutamate transporter contribute to the sustained antidepressant activity of ketamine.
  • Thu Ha Pham
  • Céline Defaix
  • Thi Mai Loan Nguyen
  • Indira Mendez-David
  • Laurent Tritschler
  • Denis J David
  • Alain M Gardier
  • Pharmacol. Biochem. Behav..2020 05;192:172913. S0091-3057(19)30648-3. doi: 10.1016/j.pbb.2020.172913.Epub 2020-03-20.

オーストラリアの早産児集団における重度未熟児網膜症(ROP)を同定するためのWINROP(オンライン予測モデル)の検証:レトロスペクティブ研究

Validation of WINROP (online prediction model) to identify severe retinopathy of prematurity (ROP) in an Australian preterm population: a retrospective study.
  • Saumil Desai
  • Sam E Athikarisamy
  • Pia Lundgren
  • Karen Simmer
  • Geoffrey C Lam
  • Eye (Lond).2020 Jul;10.1038/s41433-020-1094-7. doi: 10.1038/s41433-020-1094-7.Epub 2020-07-17.

Mfn2とIREαの相互作用を介したフェロプトーシスはヒ素誘発性非アルコール性脂肪肝炎を促進する

Ferroptosis mediated by the interaction between Mfn2 and IREα promotes arsenic-induced nonalcoholic steatohepatitis.
  • Sen Wei
  • Tianming Qiu
  • Ningning Wang
  • Xiaofeng Yao
  • Liping Jiang
  • Xue Jia
  • Ye Tao
  • Jingyuan Zhang
  • Yuhan Zhu
  • Guang Yang
  • Xiaofang Liu
  • Shuang Liu
  • Xiance Sun
  • Environ. Res..2020 Jun;188:109824. S0013-9351(20)30719-2. doi: 10.1016/j.envres.2020.109824.Epub 2020-06-23.

タクロリムスは、ナトリウム-カリウム-2塩化物コトランスポーターとナトリウム-塩化物コトランスポーターの活性化を介して、4型バルター症候群モデルマウスの表現型を改善する

Tacrolimus ameliorates the phenotypes of type 4 Bartter syndrome model mice through activation of sodium-potassium-2 chloride cotransporter and sodium-chloride cotransporter.
  • Yoshiaki Matsuura
  • Naohiro Nomura
  • Wakana Shoda
  • Takayasu Mori
  • Kiyoshi Isobe
  • Koichiro Susa
  • Fumiaki Ando
  • Eisei Sohara
  • Tatemitsu Rai
  • Shinichi Uchida
  • Biochem. Biophys. Res. Commun..2019 09;517(2):364-368. S0006-291X(19)31440-8. doi: 10.1016/j.bbrc.2019.07.086.Epub 2019-07-27.

シリカナノ粒子をマウスに単回静脈内投与した場合の1年間の慢性毒性評価とそのEx vivoヒト血液適合性

One-year chronic toxicity evaluation of single dose intravenously administered silica nanoparticles in mice and their Ex vivo human hemocompatibility.
  • Raziye Mohammadpour
  • Darwin L Cheney
  • Jason W Grunberger
  • Mostafa Yazdimamaghani
  • Jolanta Jedrzkiewicz
  • Kyle J Isaacson
  • Marina A Dobrovolskaia
  • Hamidreza Ghandehari
  • J Control Release.2020 May;324:471-481. S0168-3659(20)30304-7. doi: 10.1016/j.jconrel.2020.05.027.Epub 2020-05-25.