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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

2020年07月 みんなが読んでいる論文

進行固形癌患者を対象としたROS1/TRK阻害剤タレトレキチニブ(DS-6051b/AB-106)の米国第1相非ヒト臨床試験

US phase 1 first-in-human study of taletrectinib (DS-6051b/AB-106), a ROS1/TRK inhibitor, in patients with advanced solid tumors.
  • Kyriakos P Papadopoulos
  • Erkut Borazanci
  • Alice T Shaw
  • Ryohei Katayama
  • Yuki Shimizu
  • Viola W Zhu
  • Thomas Yang Sun
  • Heather A Wakelee
  • Russell Madison
  • Alexa B Schrock
  • Giorgio Senaldi
  • Naoki Nakao
  • Hiroyuki Hanzawa
  • Tachibana Masaya
  • Takeshi Isoyama
  • Kenji Nakamaru
  • Chenhui Deng
  • Meijing Li
  • Frank Fran
  • Qinying Zhao
  • Yanfei Gao
  • Takashi Seto
  • Pasi A Janne
  • Sai-Hong I Ou
  • Clin. Cancer Res..2020 Jun;clincanres.1630.2020. doi: 10.1158/1078-0432.CCR-20-1630.Epub 2020-06-26.

クリルオイルからのオメガ3リン脂質は、高脂肪食肥満マウスにおけるオメガ3トリアシルグリセロールよりも効果的に腸内脂肪酸の酸化を強化します

Omega-3 Phospholipids from Krill Oil Enhance Intestinal Fatty Acid Oxidation More Effectively than Omega-3 Triacylglycerols in High-Fat Diet-Fed Obese Mice.
  • Petra Kroupova
  • Evert M van Schothorst
  • Jaap Keijer
  • Annelies Bunschoten
  • Martin Vodicka
  • Ilaria Irodenko
  • Marina Oseeva
  • Petr Zacek
  • Jan Kopecky
  • Martin Rossmeisl
  • Olga Horakova
  • Nutrients.2020 Jul;12(7). E2037. doi: 10.3390/nu12072037.Epub 2020-07-09.

PVCチューブからの可塑剤の移行に対するリン脂質コーティングの効果」Chemosphere 202 (2018年7月) 742-749へのCorrigendum

Corrigendum to "Effect of phospholipid coating on the migration of plasticizers from PVC tubes" [Chemosphere 202 (July 2018) 742-749].
  • Frank Münch
  • Christine Höllerer
  • Andre Klapproth
  • Elisabeth Eckert
  • Andre Rüffer
  • Robert Cesnjevar
  • Thomas Göen
  • Chemosphere.2020 Jul;:127538. S0045-6535(20)31733-1. doi: 10.1016/j.chemosphere.2020.127538.Epub 2020-07-10.

リポソームと水性ポリウレタンからなるデュアルカプセル化された生分解性3Dスキャフォールドで、乳がん治療における局所的な薬物放出を制御する

Dual-encapsulated biodegradable 3D scaffold from liposome and waterborne polyurethane for local drug control release in breast cancer therapy.
  • Hang Yin
  • Bohong Du
  • Yue Chen
  • Nijia Song
  • Zhen Li
  • Jiehua Li
  • Feng Luo
  • Hong Tan
  • J Biomater Sci Polym Ed.2020 Jul;:1-13. doi: 10.1080/09205063.2020.1796230.Epub 2020-07-14.

室温での単層WSeのナノスケール気泡中のひずみ局在励起子のイメージング

Imaging strain-localized excitons in nanoscale bubbles of monolayer WSe at room temperature.
  • Thomas P Darlington
  • Christian Carmesin
  • Matthias Florian
  • Emanuil Yanev
  • Obafunso Ajayi
  • Jenny Ardelean
  • Daniel A Rhodes
  • Augusto Ghiotto
  • Andrey Krayev
  • Kenji Watanabe
  • Takashi Taniguchi
  • Jeffrey W Kysar
  • Abhay N Pasupathy
  • James C Hone
  • Frank Jahnke
  • Nicholas J Borys
  • P James Schuck
  • Nat Nanotechnol.2020 Jul;10.1038/s41565-020-0730-5. doi: 10.1038/s41565-020-0730-5.Epub 2020-07-13.

拡張スペクトルβ-ラクタマーゼを産生する腸内細菌を保有する介護施設入居者の腸内マイクロバイオームシグナル

Gut microbiome signatures of nursing home residents carrying Enterobacteria producing extended-spectrum β-lactamases.
  • Quentin Le Bastard
  • Guillaume Chapelet
  • Gabriel Birgand
  • Benjamin M Hillmann
  • François Javaudin
  • Niki Hayatgheib
  • Céline Bourigault
  • Pascale Bemer
  • Laure De Decker
  • Eric Batard
  • Didier Lepelletier
  • Emmanuel Montassier
  • Antimicrob Resist Infect Control.2020 Jul;9(1):107. 10.1186/s13756-020-00773-y. doi: 10.1186/s13756-020-00773-y.Epub 2020-07-14.

慢性B型肝炎ウイルス(HBV)感染におけるテノフォビル耐性の証拠。南アフリカの成人の観察的症例シリーズ

Evidence of tenofovir resistance in chronic hepatitis B virus (HBV) infection: An observational case series of South African adults.
  • Jolynne Mokaya
  • Tongai G Maponga
  • Anna L McNaughton
  • Marije Van Schalkwyk
  • Susan Hugo
  • Joshua B Singer
  • Vattipally B Sreenu
  • David Bonsall
  • Mariateresa de Cesare
  • Monique Andersson
  • Shiraaz Gabriel
  • Jantje Taljaard
  • Eleanor Barnes
  • Wolfgang Preiser
  • Christo Van Rensburg
  • Philippa C Matthews
  • J. Clin. Virol..2020 Jul;129:104548. S1386-6532(20)30290-0. doi: 10.1016/j.jcv.2020.104548.Epub 2020-07-08.

ICU入院時の直腸および鼻咽頭臨床検体から抗菌薬耐性遺伝子を直接検出するためのDNAマイクロアレイ「AMR Direct Flow Chip Kit」の評価を行った

Evaluation of the "AMR Direct Flow Chip Kit" DNA microarray for detecting antimicrobial resistance genes directly from rectal and nasopharyngeal clinical samples upon ICU admission.
  • Efthymia Protonotariou
  • Georgios Meletis
  • Dimitra Papadopoulou
  • Melania Kachrimanidou
  • Lilian Toptsi
  • Lemonia Skoura
  • Enferm. Infecc. Microbiol. Clin..2020 Jul;S0213-005X(20)30214-7. doi: 10.1016/j.eimc.2020.05.015.Epub 2020-07-11.

大環状ラクトンであるイベルメクチンとモキシデクチンは、パーキンソン病の6-ヒドロキシドパミンマウスモデルにおいて、回転行動に異なる効果を示した

The macrocyclic lactones Ivermectin and Moxidectin show differential effects on rotational behavior in the 6-hydroxydopamine mouse model of Parkinson's Disease.
  • Alicia M P Warnecke
  • Moon S Kang
  • Michael W Jakowec
  • Daryl L Davies
  • Behav. Brain Res..2020 Jul;:112804. S0166-4328(20)30503-9. doi: 10.1016/j.bbr.2020.112804.Epub 2020-07-12.

コートジボワールにおける鉤虫感染症に感染した就学年齢児、学齢児および成人に対するアルベンダゾールの有効性と安全性:第 II 相無作為化比較用量探索試験

Efficacy and safety of albendazole in hookworm-infected preschool-aged children, school-aged children and adults in Côte d'Ivoire: a phase II randomized controlled dose-finding trial.
  • Chandni Patel
  • Jean T Coulibaly
  • Daniela Hofmann
  • Yves N'Gbesso
  • Jan Hattendorf
  • Jennifer Keiser
  • Clin. Infect. Dis..2020 Jul;ciaa989. doi: 10.1093/cid/ciaa989.Epub 2020-07-15.

2009年から2018年までの中国重慶市の小児肺炎患者におけるウイルス感染と疾患転帰に及ぼす気象と大気汚染の影響:プロスペクティブ観察研究

The impact of weather and air pollution on viral infection and disease outcome among pediatric pneumonia patients in Chongqing, China from 2009 to 2018: a prospective observational study.
  • Zhi-Bo Wang
  • Luo Ren
  • Qing-Bin Lu
  • Xiao-Ai Zhang
  • Dong Miao
  • Yuan-Yuan Hu
  • Ke Dai
  • Hao Li
  • Zheng-Xiu Luo
  • Li-Qun Fang
  • En-Mei Liu
  • Wei Liu
  • Clin. Infect. Dis..2020 Jul;ciaa997. doi: 10.1093/cid/ciaa997.Epub 2020-07-15.

オランザピンとデキサメタゾンの減量投与を用いたBEP化学療法を受けている患者における好中球減少症の敗血症発生率は、標準的な制吐剤レジメンと比較して有意に高かった

Neutropenic sepsis rates in patients receiving BEP chemotherapy using olanzapine and reduced doses of dexamethasone compared to a standard antiemetic regimen.
  • Ernese Gjafa
  • Kenrick Ng
  • Tami Grunewald
  • Myria Galazi
  • Erik Skyllberg
  • Peter Wilson
  • Constantine Alifrangis
  • Jonathan Shamash
  • BJU Int..2020 Jul;doi: 10.1111/bju.15175.Epub 2020-07-15.

ヘモペキシンの間葉系発現は、リンパ節転移を伴う膵管性腺癌のリンパ節転移と関連している

Stromal expression of hemopexin is associated with lymph-node metastasis in pancreatic ductal adenocarcinoma.
  • Yukie Suzuki
  • Tatsuyuki Takadate
  • Masamichi Mizuma
  • Hiroki Shima
  • Takashi Suzuki
  • Tomoyoshi Tachibana
  • Mitsuhiro Shimura
  • Tatsuo Hata
  • Masahiro Iseki
  • Kei Kawaguchi
  • Takeshi Aoki
  • Hiroki Hayashi
  • Takanori Morikawa
  • Kei Nakagawa
  • Fuyuhiko Motoi
  • Takeshi Naitoh
  • Kazuhiko Igarashi
  • Michiaki Unno
  • PLoS ONE.2020;15(7):e0235904. PONE-D-20-00932. doi: 10.1371/journal.pone.0235904.Epub 2020-07-14.

破骨細胞様巨大細胞を有する膵臓未分化癌と破骨細胞様巨大細胞を有さない膵臓未分化癌における上皮間葉転移

Epithelial-mesenchymal transition in undifferentiated carcinoma of the pancreas with and without osteoclast-like giant cells.
  • Paola Mattiolo
  • Giulia Fiadone
  • Gaetano Paolino
  • Deyali Chatterjee
  • Riccardo Bernasconi
  • Paola Piccoli
  • Claudia Parolini
  • Mouad El Aidi
  • Nicola Sperandio
  • Giuseppe Malleo
  • Roberto Salvia
  • Lodewijk A Brosens
  • Laura D Wood
  • Aldo Scarpa
  • Rita T Lawlor
  • Claudio Luchini
  • Virchows Arch..2020 Jul;10.1007/s00428-020-02889-3. doi: 10.1007/s00428-020-02889-3.Epub 2020-07-13.

膵臓CTを用いた切除可能な膵管腺癌患者におけるアップフロント手術後の再発の推定:リスクスコアの開発と検証

Estimating Recurrence after Upfront Surgery in Patients with Resectable Pancreatic Ductal Adenocarcinoma by Using Pancreatic CT: Development and Validation of a Risk Score.
  • Dong Wook Kim
  • Seung Soo Lee
  • Seon-Ok Kim
  • Jin Hee Kim
  • Hyoung Jung Kim
  • Jae Ho Byun
  • Changhoon Yoo
  • Kyu-Pyo Kim
  • Ki-Byung Song
  • Song Cheol Kim
  • Radiology.2020 Jul;:200281. doi: 10.1148/radiol.2020200281.Epub 2020-07-14.

限局性膵管状腺癌に対するファーストラインのFOLFIRINOX vs Gemcitabineおよびnab-Paclitaxel化学療法の奏効率と生存率

Response and Survival Associated With First-line FOLFIRINOX vs Gemcitabine and nab-Paclitaxel Chemotherapy for Localized Pancreatic Ductal Adenocarcinoma.
  • Giampaolo Perri
  • Laura Prakash
  • Wei Qiao
  • Gauri R Varadhachary
  • Robert Wolff
  • David Fogelman
  • Michael Overman
  • Shubham Pant
  • Milind Javle
  • Eugene J Koay
  • Joseph Herman
  • Michael Kim
  • Naruhiko Ikoma
  • Ching-Wei Tzeng
  • Jeffrey E Lee
  • Matthew H G Katz
  • JAMA Surg.2020 Jul;2768334. doi: 10.1001/jamasurg.2020.2286.Epub 2020-07-15.

経口Toll様受容体8アゴニストであるセルガントリモドの安全性,薬物動態および薬力学:健常者を対象とした第Ia相試験

Safety, pharmacokinetics and pharmacodynamics of selgantolimod, an oral Toll-like receptor 8 agonist: a Phase Ia study in healthy subjects.
  • Maribel Reyes
  • Justin D Lutz
  • Audrey H Lau
  • Anuj Gaggar
  • Ethan P Grant
  • Adarsh Joshi
  • Richard L Mackman
  • John Ling
  • Susanna K Tan
  • Natarajan Ayithan
  • Stephane Daffis
  • Jacky Woo
  • Peiwen Wu
  • Tina Lam
  • Simon P Fletcher
  • Shyamasundaran Kottilil
  • Bhawna Poonia
  • Edward J Gane
  • Anita Mathias
  • Polina German
  • Antivir. Ther. (Lond.).2020 Jul;doi: 10.3851/IMP3363.Epub 2020-07-15.

中・大型肝細胞がん患者に対するラジオ波焼灼術(RFA)と経カテーテル動脈化学塞栓療法(TACE)の併用:長期成績のレトロスペクティブ解析

Radiofrequency Ablation (RFA) Combined with Transcatheter Arterial Chemoembolization (TACE) for Patients with Medium-to-Large Hepatocellular Carcinoma: A Retrospective Analysis of Long-Term Outcome.
  • Weiwen Liu
  • Huihong Xu
  • Xihui Ying
  • Dengke Zhang
  • Linqiang Lai
  • Linyou Wang
  • Jianfei Tu
  • Jiansong Ji
  • Med. Sci. Monit..2020 Jul;26:e923263. 923263. doi: 10.12659/MSM.923263.Epub 2020-07-15.

日本人B型慢性肝炎患者を対象としたTenofovir disoproxil fumarateとpegylated interferon-α2a追加療法のパイロット試験

Pilot study of tenofovir disoproxil fumarate and pegylated interferon-alpha 2a add-on therapy in Japanese patients with chronic hepatitis B.
  • Akihiro Matsumoto
  • Shuhei Nishiguchi
  • Hirayuki Enomoto
  • Yasuhito Tanaka
  • Noboru Shinkai
  • Chiaki Okuse
  • Jong-Hon Kang
  • Takeshi Matsui
  • Shiho Miyase
  • Hiroshi Yatsuhashi
  • Shinya Nagaoka
  • Tatsuo Kanda
  • Masaru Enomoto
  • Ryoko Yamada
  • Naoki Hiramatsu
  • Satoru Saito
  • Koichi Takaguchi
  • Kiyoaki Ito
  • Tsutomu Masaki
  • Daisuke Morihara
  • Masataka Tsuge
  • Kazuaki Chayama
  • Fusao Ikeda
  • Tatehiro Kagawa
  • Yasuteru Kondo
  • Kazumoto Murata
  • Eiji Tanaka
  • J. Gastroenterol..2020 Jul;10.1007/s00535-020-01707-6. doi: 10.1007/s00535-020-01707-6.Epub 2020-07-14.

2つの転写因子を誘導することで、根をシュート茎の特徴を持つ器官に人工的に変換した

An Artificial Conversion of Roots into Organs with Shoot Stem Characteristics by Inducing Two Transcription Factors.
  • Shigeru Hanano
  • Hajime Tomatsu
  • Ai Ohnishi
  • Koichi Kobayashi
  • Yuki Kondo
  • Shigeyuki Betsuyaku
  • Eiji Takita
  • Yoshiyuki Ogata
  • Keishi Ozawa
  • Kunihiro Suda
  • Tsutomu Hosouchi
  • Takahiro Nagase
  • Hideyuki Suzuki
  • Nozomu Sakurai
  • Hiroshi Masumoto
  • Hiroo Fukuda
  • Daisuke Shibata
  • iScience.2020 Jul;:101332. S2589-0042(20)30519-8. doi: 10.1016/j.isci.2020.101332.Epub 2020-07-12.

汚染土壌に生育したTriticum aestivumのカドミウムと鉛の固定化に及ぼす3種類の土壌改良の効果の違い

Differential effects of three amendments on the immobilisation of cadmium and lead for Triticum aestivum grown on polluted soil.
  • Shengze Zhang
  • Lingtong Quan
  • Yanping Zhu
  • Jin Yan
  • Xiaoman He
  • Jia Zhang
  • Xiaoming Xu
  • Zhubing Hu
  • Feng Hu
  • Yahua Chen
  • Zhenguo Shen
  • Yan Xia
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-10079-6. doi: 10.1007/s11356-020-10079-6.Epub 2020-07-14.

ジカルボン,ジピノカルボン,ジメントールの振動円二色性スペクトルを用いて、振動励起子モデルと局所モードモデルの検証を行った

Testing the vibrational exciton and the local mode models on the instructive cases of dicarvone, dipinocarvone, and dimenthol vibrational circular dichroism spectra.
  • Giuseppe Mazzeo
  • Ernesto Santoro
  • Sergio Abbate
  • Cristiano Zonta
  • Fabrizio Fabris
  • Giovanna Longhi
  • Chirality.2020 07;32(7):907-921. doi: 10.1002/chir.23232.Epub 2020-05-07.

糖尿病および関連する代謝変化の予防のための血糖コントロールの改善の可能性。動物およびヒト研究の系統的レビュー

Potential of to Improve Glucose Control for the Prevention of Diabetes and Related Metabolic Alterations: A Systematic Review of Animal and Human Studies.
  • Esther Nova
  • Noemí Redondo-Useros
  • Rosa M Martínez-García
  • Sonia Gómez-Martínez
  • Ligia E Díaz-Prieto
  • Ascensión Marcos
  • Nutrients.2020 Jul;12(7). E2050. doi: 10.3390/nu12072050.Epub 2020-07-10.

神経内分泌新生物におけるカペシタビン・テモゾロミド(CAPTEM)レジメンに対する治療効果を予測するためのKi-67指標。レトロスペクティブな多施設研究

A Ki-67 Index to Predict Treatment Response to the Capecitabine Temozolomide (CAPTEM) Regimen in Neuroendocrine Neoplasms: A Retrospective Multicenter Study.
  • Wei Wang
  • Yu Zhang
  • Ying Peng
  • Kai-Zhou Jin
  • Yuan-Liang Li
  • Yao Liang
  • Huang-Ying Tan
  • Xian-Jun Yu
  • Zhi-Wei Zhou
  • Jie Chen
  • Neuroendocrinology.2020 Jul;000510159. doi: 10.1159/000510159.Epub 2020-07-15.