あなたは歯科・医療関係者ですか?

WHITE CROSSは、歯科・医療現場で働く方を対象に、良質な歯科医療情報の提供を目的とした会員制サイトです。

日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

2020年07月 みんなが読んでいる論文

アルファシヌクレインは、運動機能の低下に先行して、脳の微細構造と感覚誘発脳機能に進行性の変化を誘導する

Alpha-synuclein induces progressive changes in brain microstructure and sensory-evoked brain function that precedes locomotor decline.
  • Winston T Chu
  • Jesse C DeSimone
  • Cara J Riffe
  • Han Liu
  • Paramita Chakrabarty
  • Benoit I Giasson
  • Vinata Vedam-Mai
  • David E Vaillancourt
  • J. Neurosci..2020 Jul;JN-RM-0189-20. doi: 10.1523/JNEUROSCI.0189-20.2020.Epub 2020-07-15.

出版社の訂正です。散発性原発性免疫不全症コホートの全ゲノム配列決定

Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort.
  • James E D Thaventhiran
  • Hana Lango Allen
  • Oliver S Burren
  • William Rae
  • Daniel Greene
  • Emily Staples
  • Zinan Zhang
  • James H R Farmery
  • Ilenia Simeoni
  • Elizabeth Rivers
  • Jesmeen Maimaris
  • Christopher J Penkett
  • Jonathan Stephens
  • Sri V V Deevi
  • Alba Sanchis-Juan
  • Nicholas S Gleadall
  • Moira J Thomas
  • Ravishankar B Sargur
  • Pavels Gordins
  • Helen E Baxendale
  • Matthew Brown
  • Paul Tuijnenburg
  • Austen Worth
  • Steven Hanson
  • Rachel J Linger
  • Matthew S Buckland
  • Paula J Rayner-Matthews
  • Kimberly C Gilmour
  • Crina Samarghitean
  • Suranjith L Seneviratne
  • David M Sansom
  • Andy G Lynch
  • Karyn Megy
  • Eva Ellinghaus
  • David Ellinghaus
  • Silje F Jorgensen
  • Tom H Karlsen
  • Kathleen E Stirrups
  • Antony J Cutler
  • Dinakantha S Kumararatne
  • Anita Chandra
  • J David M Edgar
  • Archana Herwadkar
  • Nichola Cooper
  • Sofia Grigoriadou
  • Aarnoud P Huissoon
  • Sarah Goddard
  • Stephen Jolles
  • Catharina Schuetz
  • Felix Boschann
  • Paul A Lyons
  • Matthew E Hurles
  • Sinisa Savic
  • Siobhan O Burns
  • Taco W Kuijpers
  • Ernest Turro
  • Willem H Ouwehand
  • Adrian J Thrasher
  • Kenneth G C Smith
  • Nature.2020 Jul;10.1038/s41586-020-2556-6. doi: 10.1038/s41586-020-2556-6.Epub 2020-07-17.

ウステキヌマブはクローン病患者におけるT濾胞ヘルパー細胞の分化を阻害する

Ustekinumab inhibits T follicular helper cell differentiation in patients with Crohn's disease.
  • Anna-Maria Globig
  • Nikola Patricia Sommer
  • Katharina Wild
  • Josefine Schardey
  • Katharina Zoldan
  • Anne Kerstin Thomann
  • Lucas-Alexander Schulte
  • Rupert Schreiner
  • Wolfgang Reindl
  • Jochen Klaus
  • Christoph Mathis Schempp
  • Maike Hofmann
  • Robert Thimme
  • Tobias Boettler
  • Peter Hasselblatt
  • Cell Mol Gastroenterol Hepatol.2020 Jul;S2352-345X(20)30111-9. doi: 10.1016/j.jcmgh.2020.07.005.Epub 2020-07-14.

重症患者における先進的臓器支援(ADVOS):多臓器不全患者における初の臨床経験

Advanced organ support (ADVOS) in the critically ill: first clinical experience in patients with multiple organ failure.
  • Valentin Fuhrmann
  • Theresa Weber
  • Kevin Roedl
  • Jasmin Motaabbed
  • Adel Tariparast
  • Dominik Jarczak
  • Aritz Perez Ruiz de Garibay
  • Johannes Kluwe
  • Olaf Boenisch
  • Harald Herkner
  • John A Kellum
  • Stefan Kluge
  • Ann Intensive Care.2020 Jul;10(1):96. 10.1186/s13613-020-00714-3. doi: 10.1186/s13613-020-00714-3.Epub 2020-07-16.

ロボット支援腎部分切除術後の腫瘍学的および機能的転帰に対するマージン、虚血、合併症、スコアと新しいトリフェクタスコアとの比較。多施設シリーズの結果

Head to Head Impact of Margin, Ischemia, Complications, Score Versus a Novel Trifecta Score on Oncologic and Functional Outcomes After Robotic-assisted Partial Nephrectomy: Results of a Multicenter Series.
  • Umberto Anceschi
  • Maria Consiglia Ferriero
  • Gabriele Tuderti
  • Aldo Brassetti
  • Riccardo Bertolo
  • Umberto Capitanio
  • Alessandro Larcher
  • Juan Garisto
  • Alessandro Antonelli
  • Alexander Mottrie
  • Andrea Minervini
  • Paolo Dell'Oglio
  • Alessandro Veccia
  • Daniele Amparore
  • Andrea Mari
  • Francesco Porpiglia
  • Francesco Montorsi
  • Jihad Kaouk
  • Marco Carini
  • Riccardo Autorino
  • Michele Gallucci
  • Giuseppe Simone
  • Eur Urol Focus.2020 Jul;S2405-4569(20)30187-5. doi: 10.1016/j.euf.2020.06.021.Epub 2020-07-13.

ビタミンDによる還元型葉酸キャリアのアップレギュレーションにより、葉酸受容体αを欠損したマウスの脳内葉酸取り込みが促進される

Upregulation of reduced folate carrier by vitamin D enhances brain folate uptake in mice lacking folate receptor alpha.
  • Camille Alam
  • Susanne Aufreiter
  • Constantine J Georgiou
  • Md Tozammel Hoque
  • Richard H Finnell
  • Deborah L O'Connor
  • I David Goldman
  • Reina Bendayan
  • Proc. Natl. Acad. Sci. U.S.A..2019 08;116(35):17531-17540. 1907077116. doi: 10.1073/pnas.1907077116.Epub 2019-08-12.

プールされたゲノムワイド関連研究により、ユダヤ人の完全集団における19p12番染色体および19p13.3番染色体上の膵臓がん感受性遺伝子座が同定された

A pooled genome-wide association study identifies pancreatic cancer susceptibility loci on chromosome 19p12 and 19p13.3 in the full-Jewish population.
  • Samantha A Streicher
  • Alison P Klein
  • Sara H Olson
  • Robert C Kurtz
  • Laufey T Amundadottir
  • Andrew T DeWan
  • Hongyu Zhao
  • Harvey A Risch
  • Hum. Genet..2020 Jul;10.1007/s00439-020-02205-8. doi: 10.1007/s00439-020-02205-8.Epub 2020-07-15.

ヒト平衡ヌクレオシドトランスポーター-1とデオキシシチジンキナーゼは、エジプトの肝細胞癌患者におけるゲムシタビンの有効性を予測することができる

Human equilibrative nucleoside transporter-1 and deoxycytidine kinase can predict gemcitabine effectiveness in Egyptian patients with Hepatocellular carcinoma.
  • Fadia Attia
  • Sara Fathy
  • Maha Anani
  • Adel Hassan
  • Fawzy Attia
  • Gehan Ibrahim
  • Mona Elazab
  • J. Clin. Lab. Anal..2020 Jul;:e23457. doi: 10.1002/jcla.23457.Epub 2020-07-16.

プロトン共役型葉酸トランスポーターを介したナノ粒子状シトクロムCのグリオーマ細胞への標的送達

Targeted Delivery of Nanoparticulate Cytochrome C into Glioma Cells Through the Proton-Coupled Folate Transporter.
  • Yuriy V Kucheryavykh
  • Josue Davila
  • Jescelica Ortiz-Rivera
  • Mikhael Inyushin
  • Luis Almodovar
  • Miguel Mayol
  • Moraima Morales-Cruz
  • Alejandra Cruz-Montañez
  • Vanessa Barcelo-Bovea
  • Kai Griebenow
  • Lilia Y Kucheryavykh
  • Biomolecules.2019 04;9(4). E154. doi: 10.3390/biom9040154.Epub 2019-04-18.

難治性粘膜・関節性ベーチェット表現型の治療に対するセスキヌマブの長期有効性と安全性:多施設共同研究

Long-term effectiveness and safety of secukinumab for treatment of refractory mucosal and articular Behçet's phenotype: a multicentre study.
  • Filippo Fagni
  • Alessandra Bettiol
  • Rosaria Talarico
  • Giuseppe Lopalco
  • Elena Silvestri
  • Maria Letizia Urban
  • Paul A J Russo
  • Gerardo Di Scala
  • Giacomo Emmi
  • Domenico Prisco
  • Ann. Rheum. Dis..2020 Aug;79(8):1098-1104. annrheumdis-2020-217108. doi: 10.1136/annrheumdis-2020-217108.Epub 2020-05-07.

ビガバトリンで治療されたマウスのトランスクリプトーム解析により、網膜シグナル伝達回路に関連する遺伝子の調節障害が同定された

Transcriptome analysis in mice treated with vigabatrin identifies dysregulation of genes associated with retinal signaling circuitry.
  • Dana Walters
  • Kara R Vogel
  • Madalyn Brown
  • Xutong Shi
  • Jean-Baptiste Roullet
  • K Michael Gibson
  • Epilepsy Res..2020 Jun;166:106395. S0920-1211(20)30220-5. doi: 10.1016/j.eplepsyres.2020.106395.Epub 2020-06-20.

ナノ結晶を搭載したマイクロニードルアレイを用いたメトトレキサートの局所的かつ持続的な皮内送達。乾癬の強化された治療のための可能性

Localised and sustained intradermal delivery of methotrexate using nanocrystal-loaded microneedle arrays: Potential for enhanced treatment of psoriasis.
  • Ismaiel A Tekko
  • Andi Dian Permana
  • Lalitkumar Vora
  • Taher Hatahet
  • Helen O McCarthy
  • Ryan F Donnelly
  • Eur J Pharm Sci.2020 Jul;:105469. S0928-0987(20)30258-X. doi: 10.1016/j.ejps.2020.105469.Epub 2020-07-14.

アルゼンチン・チャコの風土病自治体における都市化、リスク層別化、シャーガス病の主要な媒介者による家屋への侵入

Urbanisation, risk stratification and house infestation with a major vector of Chagas disease in an endemic municipality of the Argentine Chaco.
  • María Sol Gaspe
  • María Del Pilar Fernández
  • Marta Victoria Cardinal
  • Gustavo Fabián Enriquez
  • Lucía Inés Rodríguez-Planes
  • Natalia Paula Macchiaverna
  • Ricardo Esteban Gürtler
  • Parasit Vectors.2020 Jun;13(1):316. 10.1186/s13071-020-04182-3. doi: 10.1186/s13071-020-04182-3.Epub 2020-06-18.

新たに非小細胞肺がんの脳転移と診断された患者において、神経症状の負担は生存予後に影響を与える

Neurological symptom burden impacts survival prognosis in patients with newly diagnosed non-small cell lung cancer brain metastases.
  • Ariane Steindl
  • Sarah Yadavalli
  • Katharina-Anna Gruber
  • Maria Seiwald
  • Brigitte Gatterbauer
  • Karin Dieckmann
  • Josa M Frischer
  • Thomas Klikovits
  • Sabine Zöchbauer-Müller
  • Anna Grisold
  • Mir Ali Reza Hoda
  • Christine Marosi
  • Georg Widhalm
  • Matthias Preusser
  • Anna Sophie Berghoff
  • Cancer.2020 Jul;doi: 10.1002/cncr.33085.Epub 2020-07-17.

自然発症冠動脈解離と動脈硬化性冠プラーク解離を比較した患者の臨床症状と転帰

Clinical Presentation and Outcome of Patients with Spontaneous Coronary Artery Dissection Versus Atherosclerotic Coronary Plaque Dissection.
  • Amin Daoulah
  • Salem M Al-Faifi
  • Mina Madan
  • Amr A Arafat
  • Ahmad S Hersi
  • Abdulaziz Alasmari
  • Francis A Clarkson
  • Vincent Ball
  • Abdullah Alkhushail
  • Abdul Salim Khan
  • Farhan M Asrar
  • Ejazul Haq
  • Mohamed Nabil Alama
  • Mazen S Faden
  • Amir Lotfi
  • Crit Pathw Cardiol.2020 Jul;doi: 10.1097/HPC.0000000000000233.Epub 2020-07-09.

KSPVPKSPVEEKGへのAl(III)結合の理論的特徴付け:神経フィラメント形成のための重要な配列と相互作用するアルミニウムの性質への洞察

Theoretical characterization of Al(III) binding to KSPVPKSPVEEKG: Insights into the propensity of aluminum to interact with key sequences for neurofilament formation.
  • Rafael Grande-Aztatzi
  • Elena Formoso
  • Jon I Mujika
  • David de Sancho
  • Xabier Lopez
  • J. Inorg. Biochem..2020 Jul;210:111169. S0162-0134(20)30197-5. doi: 10.1016/j.jinorgbio.2020.111169.Epub 2020-07-09.

肺腺癌の予後における腫瘍浸潤性フォークヘッドボックスP3陽性T細胞の検出:クラスター化腫瘍インターロイキン12サブユニットαおよびトランスフォーミング成長因子β1発現の役割の可能性

Detecting tumor-infiltrating Forkhead box P3-positive T cells in the prognosis of lung adenocarcinoma: Possible role of clustering tumor interleukin-12 subunit alpha and transforming growth factor beta 1 expression.
  • Hiroyasu Matsuoka
  • Hirochika Matsubara
  • Aya Sugimura
  • Tsuyoshi Uchida
  • Tamo Kunimitsu
  • Tomofumi Ichihara
  • Yuichiro Oonuki
  • Yoshihiro Miyauchi
  • Tetsuo Kondo
  • Hiroyuki Nakajima
  • Adv Clin Exp Med.2020 Jun;29(6):715-725. doi: 10.17219/acem/121922.

後腰椎体間固定術におけるトラネキサム酸とリバロキサバンの併用は、血栓症のリスクを増加させることなく、出血量と輸血率を安全に減少させる-プロスペクティブ、層別化、無作為化、対照試験-

Combined use of tranexamic acid and rivaroxaban in posterior lumbar interbody fusion safely reduces blood loss and transfusion rates without increasing the risk of thrombosis-a prospective, stratified, randomized, controlled trial.
  • Lu Zhang
  • Yanming Li
  • Dong Liu
  • Xing Xiao
  • Tingjin Guan
  • Hongwei Yue
  • Haipeng Xue
  • Hongming Zhou
  • Guangjun Jiao
  • Wenliang Wu
  • Hongliang Wang
  • Haichun Liu
  • Chunyang Meng
  • Zhaozhong Sun
  • Yunzhen Chen
  • Int Orthop.2020 Jul;10.1007/s00264-020-04699-3. doi: 10.1007/s00264-020-04699-3.Epub 2020-07-17.

ガボンにおけるロイヤスによる疾病負担:横断的調査

Burden of disease in Gabon caused by loiasis: a cross-sectional survey.
  • Luzia Veletzky
  • Jennifer Hergeth
  • Daniel R Stelzl
  • Johannes Mischlinger
  • Rella Zoleko Manego
  • Ghyslain Mombo-Ngoma
  • Matthew B B McCall
  • Ayôla A Adegnika
  • Selidji T Agnandji
  • Wolfram G Metzger
  • Pierre B Matsiegui
  • Heimo Lagler
  • Benjamin Mordmüller
  • Christine Budke
  • Michael Ramharter
  • Lancet Infect Dis.2020 Jun;S1473-3099(20)30256-5. doi: 10.1016/S1473-3099(20)30256-5.Epub 2020-06-22.

シェストソーマ症に対する地域社会全体での拡大治療の評価。ガーナ、グレーターアクラ地域の3つのコミュニティにおけるベースラインの感染状況と自己申告による危険因子

Assessing expanded community wide treatment for schistosomiasis: Baseline infection status and self-reported risk factors in three communities from the Greater Accra region, Ghana.
  • Lucas J Cunningham
  • Suzy J Campbell
  • Samuel Armoo
  • Artemis Koukounari
  • Victoria Watson
  • Pamela Selormey
  • J Russell Stothard
  • Bright Idun
  • Manfred Asiedu
  • Yvonne Ashong
  • Emily R Adams
  • Mike Yaw Osei-Atweneboana
  • PLoS Negl Trop Dis.2020 04;14(4):e0007973. PNTD-D-19-00851. doi: 10.1371/journal.pntd.0007973.Epub 2020-04-27.

局所領域進行性上咽頭癌患者におけるネオアジュバント化学療法後の腫瘍体積減少率の予後を検討した

Prognostic value of the tumor volume reduction rate after neoadjuvant chemotherapy in patients with locoregional advanced nasopharyngeal carcinoma.
  • Huiyun Yang
  • Yuanyuan Liu
  • Rongjun Zhang
  • Yaomin Ye
  • Qiuqiu Chen
  • Qinghua Qin
  • Liying Huang
  • Xi Li
  • Rui Cai
  • Huaying Tang
  • Wei Jiang
  • Oral Oncol..2020 Jul;110:104897. S1368-8375(20)30333-X. doi: 10.1016/j.oraloncology.2020.104897.Epub 2020-07-14.

虚血/再灌流損傷後のラット小腸神経筋機能の適応変化におけるヒアルロナンの関与

Involvement of hyaluronan in the adaptive changes of the rat small intestine neuromuscular function after ischemia/reperfusion injury.
  • Michela Bistoletti
  • Annalisa Bosi
  • Ilaria Caon
  • Anna Maria Chiaravalli
  • Paola Moretto
  • Angelo Genoni
  • Elisabetta Moro
  • Evgenia Karousou
  • Manuela Viola
  • Francesca Crema
  • Andreina Baj
  • Alberto Passi
  • Davide Vigetti
  • Cristina Giaroni
  • Sci Rep.2020 Jul;10(1):11521. 10.1038/s41598-020-67876-9. doi: 10.1038/s41598-020-67876-9.Epub 2020-07-13.

結核患者における集中治療薬モニタリング(TDM)を用いたフルオロキノロン曝露の改善のプロスペクティブ評価(PERFECT):プロスペクティブ多施設コホート研究の研究プロトコール

Prospective evaluation of improving fluoroquinolone exposure using centralised therapeutic drug monitoring (TDM) in patients with tuberculosis (PERFECT): a study protocol of a prospective multicentre cohort study.
  • Simone Hj van den Elsen
  • Marieke Gg Sturkenboom
  • Onno Akkerman
  • Linda Barkane
  • Judith Bruchfeld
  • Geoffrey Eather
  • Scott K Heysell
  • Henadz Hurevich
  • Liga Kuksa
  • Heinke Kunst
  • Johanna Kuhlin
  • Katerina Manika
  • Charalampos Moschos
  • Stellah G Mpagama
  • Marcela Muñoz Torrico
  • Alena Skrahina
  • Giovanni Sotgiu
  • Marina Tadolini
  • Simon Tiberi
  • Francesca Volpato
  • Tjip S van der Werf
  • Malcolm R Wilson
  • Joaquin Zúñiga
  • Daan J Touw
  • Giovanni B Migliori
  • Jan-Willem Alffenaar
  • BMJ Open.2020 Jun;10(6):e035350. bmjopen-2019-035350. doi: 10.1136/bmjopen-2019-035350.Epub 2020-06-16.

心不全患者の心臓突然死の管理における新たなアプローチ-交感神経系を標的にして

New Approaches in the Management of Sudden Cardiac Death in Patients with Heart Failure-Targeting the Sympathetic Nervous System.
  • Márcio Galindo Kiuchi
  • Janis Marc Nolde
  • Humberto Villacorta
  • Revathy Carnagarin
  • Justine Joy Su-Yin Chan
  • Leslie Marisol Lugo-Gavidia
  • Jan K Ho
  • Vance B Matthews
  • Girish Dwivedi
  • Markus P Schlaich
  • Int J Mol Sci.2019 May;20(10). E2430. doi: 10.3390/ijms20102430.Epub 2019-05-16.