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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

2020年07月 みんなが読んでいる論文

27-ヒドロキシコレステロールの性差炎症効果は、エストロゲンのシグナル伝達の違いを介して媒介される

Sex-opposed inflammatory effects of 27-hydroxycholesterol are mediated via differences in estrogen signaling.
  • Tom Houben
  • Albert V Bitorina
  • Yvonne Oligschlaeger
  • Mike Lj Jeurissen
  • Sander Rensen
  • S Eleonore Köhler
  • Marit Westerterp
  • Dieter Lütjohann
  • Jan Theys
  • Andrea Romano
  • Jogchum Plat
  • Ronit Shiri-Sverdlov
  • J. Pathol..2020 Aug;251(4):429-439. doi: 10.1002/path.5477.Epub 2020-07-07.

N-メチル-d-アスパラギン酸受容体拮抗薬MK-801(ジゾシルピン)がマウスの骨の恒常性に及ぼす影響

Effects of N-methyl-d-aspartate receptor antagonist MK-801 (dizocilpine) on bone homeostasis in mice.
  • Shuichi Kiyohara
  • Nobuhiro Sakai
  • Kazuaki Handa
  • Tomoyuki Yamakawa
  • Koji Ishikawa
  • Masahiro Chatani
  • Akiko Karakawa
  • Yuki Azetsu
  • Motohiro Munakata
  • Masahiko Ozeki
  • Takako Negishi-Koga
  • Masamichi Takami
  • J Oral Biosci.2020 Jun;62(2):131-138. S1349-0079(20)30046-3. doi: 10.1016/j.job.2020.03.003.Epub 2020-04-11.

顔面神経シュワノーマに対する定位放射線手術における解剖学的分節浸潤の影響。国際的な多施設コホート研究

Effect of Anatomic Segment Involvement on Stereotactic Radiosurgery for Facial Nerve Schwannomas: An International Multicenter Cohort Study.
  • Gautam U Mehta
  • Gregory P Lekovic
  • William H Slattery
  • Derald E Brackmann
  • Hao Long
  • Hideyuki Kano
  • Douglas Kondziolka
  • Monica Mureb
  • Kenneth Bernstein
  • Anne-Marie Langlois
  • David Mathieu
  • Ahmed M Nabeel
  • Wael A Reda
  • Sameh R Tawadros
  • Khaled Abdelkarim
  • Amr M N El-Shehaby
  • Reem M Emad
  • Nasser Mohammed
  • Dusan Urgosik
  • Roman Liscak
  • Cheng-Chia Lee
  • Huai-Che Yang
  • Amanallah Montazeripouragha
  • Anthony M Kaufmann
  • Krishna C Joshi
  • Gene H Barnett
  • Daniel M Trifiletti
  • L Dade Lunsford
  • Jason P Sheehan
  • Neurosurgery.2020 Jul;nyaa313. doi: 10.1093/neuros/nyaa313.Epub 2020-07-20.

ブラジルの様々な牛種における Rhipicephalus microplus ダニと Anaplasma marginale 感染との相関

Correlation between Rhipicephalus microplus ticks and Anaplasma marginale infection in various cattle breeds in Brazil.
  • Kauê Rodriguez Martins
  • Marcos Valério Garcia
  • Paulino Bonatte-Junior
  • Pãmella Oliveira Duarte
  • Leandro Oliveira Souza de Higa
  • Bárbara Guimarães Csordas
  • Jacqueline Cavalcante Barros
  • Renato Andreotti
  • Exp. Appl. Acarol..2020 Jul;10.1007/s10493-020-00514-1. doi: 10.1007/s10493-020-00514-1.Epub 2020-07-17.

中国南西部のHIV/AIDS患者の長期死亡率に及ぼす抗レトロウイルス療法開始時のAIDS定義イベントの影響:レトロスペクティブコホート研究

Effect of AIDS-defining events at initiation of antiretroviral therapy on long-term mortality of HIV/AIDS patients in Southwestern China: a retrospective cohort study.
  • Yunxuan Huang
  • Oulu Zhou
  • Zhigang Zheng
  • Yuexiang Xu
  • Yi Shao
  • Chunwei Qin
  • Fengxiang Qin
  • Jingzhen Lai
  • Huifang Liu
  • Rongfeng Chen
  • Li Ye
  • Hao Liang
  • Xionglin Qin
  • Junjun Jiang
  • AIDS Res Ther.2020 Jul;17(1):44. 10.1186/s12981-020-00300-4. doi: 10.1186/s12981-020-00300-4.Epub 2020-07-17.

B型慢性肝炎に対するベシフォビルジピボキシルマレイン酸塩の144週間投与。第 3 相試験の非盲検延長試験

Besifovir Dipivoxil Maleate 144-Week Treatment of Chronic Hepatitis B: An Open-Label Extensional Study of a Phase 3 Trial.
  • Hyung Joon Yim
  • Won Kim
  • Sang Hoon Ahn
  • Jin Mo Yang
  • Jae Young Jang
  • Yong Oh Kweon
  • Yong Kyun Cho
  • Yoon Jun Kim
  • Gun Young Hong
  • Dong Joon Kim
  • Young Kul Jung
  • Soon Ho Um
  • Joo Hyun Sohn
  • Jin Woo Lee
  • Sung Jae Park
  • Byung Seok Lee
  • Ju Hyun Kim
  • Hong Soo Kim
  • Seung Kew Yoon
  • Moon Young Kim
  • Kwan Sik Lee
  • Young Suk Lim
  • Wan Sik Lee
  • Kwang-Hyub Han
  • Am. J. Gastroenterol..2020 May;doi: 10.14309/ajg.0000000000000605.Epub 2020-05-01.

ベバシズマブは化学療法誘発性脾臓機能亢進症の管理における部分的な脾臓塞栓術の有効性に影響を与えない

Bevacizumab Does Not Influence the Efficacy of Partial Splenic Embolization in the Management of Chemotherapy-Induced Hypersplenism.
  • Alexandre A Jácome
  • Aki Ohinata
  • Armeen Mahvash
  • Michael J Overman
  • Bryan Kee
  • David Fogelman
  • Van K Morris
  • Benny Johnson
  • Nicole D Rothschild
  • Robert A Wolff
  • Cathy Eng
  • Clin Colorectal Cancer.2020 Jun;S1533-0028(20)30065-7. doi: 10.1016/j.clcc.2020.04.007.Epub 2020-06-12.

耐性統合失調症患者におけるCOVID-19の好発進と本剤とパルミチン酸パリペリドンの併用についての考察

[Thoughts on a favourable evolution of a COVID-19 in a patient with resistant schizophrenia and on a combination of clozapine and paliperidone palmitate].
  • N Bouaziz
  • H Ben Rejeb
  • S Ateb
  • T Fourati
  • F Chammas
  • D Baha
  • R Rosetti
  • K Kalalou
  • G Saba
  • R Benadhira
  • D Januel
  • Encephale.2020 Jun;46(3S):S126-S127. S0013-7006(20)30094-4. doi: 10.1016/j.encep.2020.05.009.Epub 2020-05-21.

ゴルジ体の組織はプロテアソーム分解によって制御されている

Golgi organization is regulated by proteasomal degradation.
  • Avital Eisenberg-Lerner
  • Ron Benyair
  • Noa Hizkiahou
  • Neta Nudel
  • Roey Maor
  • Matthias P Kramer
  • Merav D Shmueli
  • Inbal Zigdon
  • Marina Cherniavsky Lev
  • Adi Ulman
  • Jitka Yehudith Sagiv
  • Molly Dayan
  • Bareket Dassa
  • Mercedes Rosenwald
  • Idit Shachar
  • Jie Li
  • Yanzhuang Wang
  • Nili Dezorella
  • Suman Khan
  • Ziv Porat
  • Eyal Shimoni
  • Ori Avinoam
  • Yifat Merbl
  • Nat Commun.2020 01;11(1):409. 10.1038/s41467-019-14038-9. doi: 10.1038/s41467-019-14038-9.Epub 2020-01-21.

原発性骨粗鬆症における間葉系幹細胞集団の転写プロファイルは明瞭であり、骨形成阻害剤の過剰発現を示す

The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitors.
  • Peggy Benisch
  • Tatjana Schilling
  • Ludger Klein-Hitpass
  • Sönke P Frey
  • Lothar Seefried
  • Nadja Raaijmakers
  • Melanie Krug
  • Martina Regensburger
  • Sabine Zeck
  • Thorsten Schinke
  • Michael Amling
  • Regina Ebert
  • Franz Jakob
  • PLoS ONE.2012;7(9):e45142. PONE-D-12-12518. doi: 10.1371/journal.pone.0045142.Epub 2012-09-24.

大動脈弁狭窄症患者における脳卒中量と大動脈弁面積の推定.心エコー検査と心血管磁気共鳴検査の比較

Estimation of Stroke Volume and Aortic Valve Area in Patients with Aortic Stenosis: A Comparison of Echocardiography versus Cardiovascular Magnetic Resonance.
  • Ezequiel Guzzetti
  • Romain Capoulade
  • Lionel Tastet
  • Julio Garcia
  • Florent Le Ven
  • Marie Arsenault
  • Elisabeth Bédard
  • Eric Larose
  • Marie-Annick Clavel
  • Philippe Pibarot
  • J Am Soc Echocardiogr.2020 Jun;S0894-7317(20)30205-4. doi: 10.1016/j.echo.2020.03.020.Epub 2020-06-21.

振動分光マップ、振動分光、分子間相互作用

Vibrational Spectroscopic Map, Vibrational Spectroscopy, and Intermolecular Interaction.
  • Carlos R Baiz
  • Bartosz Błasiak
  • Jens Bredenbeck
  • Minhaeng Cho
  • Jun-Ho Choi
  • Steven A Corcelli
  • Arend G Dijkstra
  • Chi-Jui Feng
  • Sean Garrett-Roe
  • Nien-Hui Ge
  • Magnus W D Hanson-Heine
  • Jonathan D Hirst
  • Thomas L C Jansen
  • Kijeong Kwac
  • Kevin J Kubarych
  • Casey H Londergan
  • Hiroaki Maekawa
  • Mike Reppert
  • Shinji Saito
  • Santanu Roy
  • James L Skinner
  • Gerhard Stock
  • John E Straub
  • Megan C Thielges
  • Keisuke Tominaga
  • Andrei Tokmakoff
  • Hajime Torii
  • Lu Wang
  • Lauren J Webb
  • Martin T Zanni
  • Chem. Rev..2020 Jun;doi: 10.1021/acs.chemrev.9b00813.Epub 2020-06-29.

COVID-19患者における呼吸不全に対する静脈体外膜酸素療法.北米の主要な学術医療センターからの初期の経験

Veno-venous Extracorporeal Membrane Oxygenation for Respiratory Failure in COVID-19 Patients: Early Experience From a Major Academic Medical Center in North America.
  • Asishana A Osho
  • Philicia Moonsamy
  • Kathryn A Hibbert
  • Kenneth T Shelton
  • John M Trahanas
  • Rizwan Q Attia
  • Jordan P Bloom
  • Michael T Onwugbufor
  • David A D'Alessandro
  • Mauricio A Villavicencio
  • Thoralf M Sundt
  • Jerome C Crowley
  • Yuval Raz
  • Masaki Funamoto
  • Ann. Surg..2020 08;272(2):e75-e78. 00000658-202008000-00023. doi: 10.1097/SLA.0000000000004084.

シロイヌナズナにおけるABAシグナル伝達ターミネーターによる種子発芽・育苗阻害のカウンターアクション(英文

Counteraction of ABA-Mediated Inhibition of Seed Germination and Seedling Establishment by ABA Signaling Terminator in Arabidopsis.
  • Zhijuan Wang
  • Ziyin Ren
  • Chunhong Cheng
  • Tao Wang
  • Hongtao Ji
  • Yang Zhao
  • Zhiping Deng
  • Liya Zhi
  • Jingjing Lu
  • Xinying Wu
  • Shimin Xu
  • Mengmeng Cao
  • Hongtao Zhao
  • Liu Liu
  • Jiankang Zhu
  • Xia Li
  • Mol Plant.2020 Jun;S1674-2052(20)30212-4. doi: 10.1016/j.molp.2020.06.011.Epub 2020-06-30.

犬および猫における外傷性頭蓋骨骨折。神経学的およびコンピュータ断層撮影機能の比較分析

Traumatic skull fractures in dogs and cats: A comparative analysis of neurological and computed tomographic features.
  • Pablo Amengual-Batle
  • Roberto José-López
  • Alexane Durand
  • Michal Czopowicz
  • Elsa Beltran
  • Julien Guevar
  • Kali Lazzerini
  • Steven De Decker
  • Karen Muñana
  • Peter Early
  • Christopher Mariani
  • Natasha Olby
  • Nicholas Petrovitch
  • Rodrigo Gutierrez-Quintana
  • J. Vet. Intern. Med..2020 Jul;doi: 10.1111/jvim.15838.Epub 2020-07-20.

ウミウシは、海藻類である Laurencia dendroidea とその近縁種において化学防御の誘導を促進する

The sea-hare Aplysia brasiliana promotes induction in chemical defense in the seaweed Laurencia dendroidea and in their congeneric neighbors.
  • Renato C Pereira
  • Nathália Nocchi
  • María L Souto
  • José J Fernández
  • Manuel Norte
  • Heitor M Duarte
  • Angélica R Soares
  • Plant Physiol. Biochem..2020 Jun;154:295-303. S0981-9428(20)30244-8. doi: 10.1016/j.plaphy.2020.05.020.Epub 2020-06-17.

CYP3A4誘導を抑制する新たなアプローチにより、最適なADMETプロファイルを持つ強力なB型肝炎ウイルス(HBV)カプシドインヒビターが発見されました

A New Approach of Mitigating CYP3A4 Induction Led to the Discovery of Potent Hepatitis B Virus (HBV) Capsid Inhibitor with Optimal ADMET Profiles.
  • Xianfeng Lin
  • Houguang Shi
  • Weixing Zhang
  • Zongxing Qiu
  • Zheng Zhou
  • Fabian Dey
  • Sheng Zhong
  • Hongxia Qiu
  • Jianxun Xie
  • Xue Zhou
  • Guang Yang
  • Guozhi Tang
  • Hong C Shen
  • Wei Zhu
  • J. Med. Chem..2019 11;62(22):10352-10361. doi: 10.1021/acs.jmedchem.9b01421.Epub 2019-11-18.

非小細胞肺癌におけるALK遺伝子増幅とコピー数増加の非生産的効果.NSCLCにおけるALK遺伝子増幅とコピー数ゲイン

Unproductive Effects of ALK Gene Amplification and Copy Number Gain in Non-Small-Cell Lung Cancer. ALK Gene Amplification and Copy Gain in NSCLC.
  • Federica Zito Marino
  • Gerardo Botti
  • Gabriella Aquino
  • Stefano Ferrero
  • Gabriella Gaudioso
  • Alessandro Palleschi
  • Danilo Rocco
  • Rosario Salvi
  • Maria Carolina Micheli
  • Pietro Micheli
  • Alessandro Morabito
  • Gaetano Rocco
  • Antonio Giordano
  • Rossella De Cecio
  • Renato Franco
  • Int J Mol Sci.2020 Jul;21(14). E4927. doi: 10.3390/ijms21144927.Epub 2020-07-12.

ルセットバット樹状細胞は、プロ炎症性疾患メディエーターをダウンレギュレーションしながら、インターフェロン関連遺伝子のアップレギュレーションによってマールブルグウイルス媒介の抗ウイルス応答を克服する

Rousette Bat Dendritic Cells Overcome Marburg Virus-Mediated Antiviral Responses by Upregulation of Interferon-Related Genes While Downregulating Proinflammatory Disease Mediators.
  • Joseph Prescott
  • Jonathan C Guito
  • Jessica R Spengler
  • Catherine E Arnold
  • Amy J Schuh
  • Brian R Amman
  • Tara K Sealy
  • Lisa W Guerrero
  • Gustavo F Palacios
  • Mariano Sanchez-Lockhart
  • Cesar G Albariño
  • Jonathan S Towner
  • mSphere.2019 12;4(6). e00728-19. doi: 10.1128/mSphere.00728-19.Epub 2019-12-04.

好中球対リンパ球比(NLR)が高いと,チカグレラーとの二重抗血小板療法を受けているACS患者において,最適な血小板抑制効果が得られず,大規模な心血管虚血イベントが発生するリスクが高くなる.

Higher neutrophil-to-lymphocyte ratio (NLR) increases the risk of suboptimal platelet inhibition and major cardiovascular ischemic events among ACS patients receiving dual antiplatelet therapy with ticagrelor.
  • Monica Verdoia
  • Matteo Nardin
  • Rocco Gioscia
  • Federica Negro
  • Marco Marcolongo
  • Harry Suryapranata
  • Elvin Kedhi
  • Giuseppe De Luca
  • Vascul. Pharmacol..2020 Jul;:106765. S1537-1891(20)30072-0. doi: 10.1016/j.vph.2020.106765.Epub 2020-07-15.

首都の主要パンデミック対策センターのCOVID-19の経験。トルコでのパンデミックの最初の1ヶ月間の結果

COVID-19 experience of the major pandemic response center in the capital: Results of the pandemic's first month in Turkey.
  • Rahmet Güner
  • İmran Hasanoğlu
  • Bircan Kayaaslan
  • Adalet Aypak
  • Ayşe Kaya Kalem
  • Fatma Eser
  • Burcu Özdemir
  • Elif Mukime Sarıcaoğlu
  • Müge Ayhan
  • Yeşim Aybar Bilir
  • Işıl Özkoçak Turan
  • Deniz Erdem
  • Nevzat Mehmet Mutlu
  • Turan Buzğan
  • Bedia Dinç
  • Esragül Akıncı
  • Turk J Med Sci.2020 07;doi: 10.3906/sag-2006-164.Epub 2020-07-19.

オートファジーとFGF21レベルが低いにもかかわらず、高タンパク食は低タンパク食よりも効果的に肝脂肪を減少させる

High-protein diet more effectively reduces hepatic fat than low-protein diet despite lower autophagy and FGF21 levels.
  • Chenchen Xu
  • Mariya Markova
  • Nicole Seebeck
  • Anne Loft
  • Silke Hornemann
  • Thomas Gantert
  • Stefan Kabisch
  • Kathleen Herz
  • Jennifer Loske
  • Mario Ost
  • Verena Coleman
  • Frederick Klauschen
  • Anke Rosenthal
  • Volker Lange
  • Jürgen Machann
  • Susanne Klaus
  • Tilman Grune
  • Stephan Herzig
  • Olga Pivovarova-Ramich
  • Andreas F H Pfeiffer
  • Liver Int..2020 Jul;doi: 10.1111/liv.14596.Epub 2020-07-11.

CD27 および CD70 欠損症における臨床および免疫学的表現型の拡大と移植転帰

Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency.
  • Sujal Ghosh
  • Sevgi Köstel Bal
  • Emily S J Edwards
  • Bethany Pillay
  • Raúl Jimenez-Heredia
  • Geetha Rao
  • Funda Erol Cipe
  • Elisabeth Salzer
  • Samaneh Zoghi
  • Hassan Abolhassani
  • Tooba Momen
  • Emma Gostick
  • David A Price
  • Yu Zhang
  • Andrew J Oler
  • Claudia Gonzaga-Jauregui
  • Baran Erman
  • Ayse Metin
  • Inci Ilhan
  • Sule Haskologlu
  • Candan Islamoglu
  • Kubra Baskin
  • Serdar Ceylaner
  • Ebru Yilmaz
  • Ekrem Unal
  • Musa Karakukcu
  • Dagmar Berghuis
  • Theresa Cole
  • Aditya Kumar Gupta
  • Fabian Hauck
  • Andy Hoepelman
  • Safa Baris
  • Elif Karakoc-Aydiner
  • Ahmet Ozen
  • Leo Kager
  • Dirk Holzinger
  • Michael Paulussen
  • Renate Krüger
  • Roland Meisel
  • Prasad Thomas Oommen
  • Emma C Morris
  • Benedicte Neven
  • Austen J J Worth
  • Joris M van Montfrans
  • Pieter Fraaij
  • Sharon Choo
  • Figen Dogu
  • E Graham Davies
  • Siobhan Burns
  • Gregor Dueckers
  • Ruy Perez Becker
  • Horst von Bernuth
  • Sylvain Latour
  • Maura Faraci
  • Marco Gattorno
  • Helen Su
  • Qiang Pan-Hammarström
  • Lennart Hammarström
  • Michael J Lenardo
  • Cindy S Ma
  • Tim Niehues
  • Asghar Aghamohammadi
  • Nima Rezaei
  • Aydan Ikinciogullari
  • Stuart G Tangye
  • Arjan C Lankester
  • Kaan Boztug
  • Blood.2020 Jun;blood.2020006738. doi: 10.1182/blood.2020006738.Epub 2020-06-30.