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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

2020年07月 みんなが読んでいる論文

細胞の分化とリプログラミングにおけるゲノムワイドなRループのランドスケープ

Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming.
  • Pengze Yan
  • Zunpeng Liu
  • Moshi Song
  • Zeming Wu
  • Wei Xu
  • Kuan Li
  • Qianzhao Ji
  • Si Wang
  • Xiaoqian Liu
  • Kaowen Yan
  • Concepcion Rodriguez Esteban
  • Weimin Ci
  • Juan Carlos Izpisua Belmonte
  • Wei Xie
  • Jie Ren
  • Weiqi Zhang
  • Qianwen Sun
  • Jing Qu
  • Guang-Hui Liu
  • Cell Rep.2020 Jul;32(1):107870. S2211-1247(20)30851-2. doi: 10.1016/j.celrep.2020.107870.

がん患者におけるうつ病および不安の症状に対するコーピングスキル訓練の効果とモデレーター。集計データおよび個別の患者データのメタアナリシス

Effects and moderators of coping skills training on symptoms of depression and anxiety in patients with cancer: Aggregate data and individual patient data meta-analyses.
  • L M Buffart
  • M A C Schreurs
  • H J G Abrahams
  • J Kalter
  • N K Aaronson
  • P B Jacobsen
  • R U Newton
  • K S Courneya
  • J Armes
  • C Arving
  • A M Braamse
  • Y Brandberg
  • J Dekker
  • R J Ferguson
  • M F Gielissen
  • B Glimelius
  • M M Goedendorp
  • K D Graves
  • S P Heiney
  • R Horne
  • M S Hunter
  • B Johansson
  • L L Northouse
  • H S Oldenburg
  • J B Prins
  • J Savard
  • M van Beurden
  • S W van den Berg
  • J Brug
  • H Knoop
  • I M Verdonck-de Leeuw
  • Clin Psychol Rev.2020 Jun;80:101882. S0272-7358(20)30070-2. doi: 10.1016/j.cpr.2020.101882.Epub 2020-06-25.

人種は動物性タンパク質代謝物である1-メチルヒスチジンと中年成人の血圧との関連を修飾する:Bogalusa Heart Study

Race modifies the association between animal protein metabolite 1-methylhistidine and blood pressure in middle-aged adults: the Bogalusa Heart Study.
  • Alexander C Razavi
  • Lydia A Bazzano
  • Jiang He
  • Seamus P Whelton
  • Casey M Rebholz
  • Camilo Fernandez
  • Marie Krousel-Woods
  • Changwei Li
  • Mengyao Shi
  • Jovia L Nierenberg
  • Shengxu Li
  • Jason Kinchen
  • Xuenan Mi
  • Tanika N Kelly
  • J. Hypertens..2020 Jul;doi: 10.1097/HJH.0000000000002571.Epub 2020-07-06.

プラチナ抵抗性の転移性尿路粘膜がん患者に対するカボザンチニブ:非盲検、単施設、第2相試験

Cabozantinib in patients with platinum-refractory metastatic urothelial carcinoma: an open-label, single-centre, phase 2 trial.
  • Andrea B Apolo
  • Rosa Nadal
  • Yusuke Tomita
  • Nicole N Davarpanah
  • Lisa M Cordes
  • Seth M Steinberg
  • Liang Cao
  • Howard L Parnes
  • Rene Costello
  • Maria J Merino
  • Les R Folio
  • Liza Lindenberg
  • Mark Raffeld
  • Jeffrey Lin
  • Min-Jung Lee
  • Sunmin Lee
  • Sylvia V Alarcon
  • Akira Yuno
  • Nancy A Dawson
  • Kimaada Allette
  • Arpita Roy
  • Dinuka De Silva
  • Molly M Lee
  • Tristan M Sissung
  • William D Figg
  • Piyush K Agarwal
  • John J Wright
  • Yangmin M Ning
  • James L Gulley
  • William L Dahut
  • Donald P Bottaro
  • Jane B Trepel
  • Lancet Oncol..2020 Jul;S1470-2045(20)30202-3. doi: 10.1016/S1470-2045(20)30202-3.Epub 2020-07-06.

単細胞ゲノミクスは、骨髄性新生物における突然変異のエピスタシスから逃れるための遺伝的・分子的基盤を明らかにした

Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms.
  • Justin Taylor
  • Xiaoli Mi
  • Khrystyna Dilai North
  • Moritz Binder
  • Alexander Penson
  • Terra L Lasho
  • Katherine Knorr
  • Michael Haddadin
  • Bo Liu
  • Joseph Pangallo
  • Salima Benbarche
  • Daniel Howard Wiseman
  • Ayalew Tefferi
  • Stephanie Halene
  • Yang Liang
  • Mrinal M Patnaik
  • Robert K Bradley
  • Omar Abdel-Wahab
  • Blood.2020 Jul;blood.2020006868. doi: 10.1182/blood.2020006868.Epub 2020-07-08.

両側慢性硬膜下血腫の片側退院後の対側血腫増殖に対する再手術のリスクを予測する予後スコアリングシステムの開発

Development of a prognostic scoring system to predict risk of reoperation for contralateral hematoma growth after unilateral evacuation of bilateral chronic subdural hematoma.
  • John J Y Zhang
  • Shilin Wang
  • Aaron Song Chuan Foo
  • Ming Yang
  • Boon Leong Quah
  • Ira Siyang Sun
  • Zhi Xu Ng
  • Kejia Teo
  • Boon Chuan Pang
  • Eugene Weiren Yang
  • Sein Lwin
  • Ning Chou
  • Shiong Wen Low
  • Tseng Tsai Yeo
  • Thomas Santarius
  • Vincent Diong Weng Nga
  • J Clin Neurosci.2020 Jun;S0967-5868(20)31317-5. doi: 10.1016/j.jocn.2020.06.009.Epub 2020-06-29.

たばこを吸う人、電子ニコチン送達システムを使用する人、歯周炎の有無にかかわらず非喫煙者から採取した歯肉下口腔バイオフィルムサンプルから分離された病原性細菌の定量化

Quantification of pathogenic bacteria in the subgingival oral biofilm samples collected from cigarette-smokers, individuals using electronic nicotine delivery systems and non-smokers with and without periodontitis.
  • Fahad M Aldakheel
  • Shatha A Alduraywish
  • Poojdev Jhugroo
  • Chitra Jhugroo
  • Darshan Devang Divakar
  • Arch. Oral Biol..2020 Jun;117:104793. S0003-9969(20)30171-0. doi: 10.1016/j.archoralbio.2020.104793.Epub 2020-06-06.

チオアダタンセリン及びそのジアルキル化生成物の合成と生物学的評価を行った

Synthesis and biological evaluation of thioadatanserin and its dialkylated products as partial 5-HTR agonists and 5-HTR antagonists for potential use in depression and anxiety disorders.
  • Colleen A Evans
  • Andrea Zuluaga
  • Diego Vasquez Matute
  • Sarah Baradaran-Noviri
  • Natalia Perez-Cervantes
  • Maxime A Siegler
  • Bioorg. Med. Chem. Lett..2020 Aug;30(16):127358. S0960-894X(20)30469-8. doi: 10.1016/j.bmcl.2020.127358.Epub 2020-06-17.

グラム陰性菌のフルオロキノロン耐性に対処するトポイソメラーゼ阻害剤

Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria.
  • Colin K Skepper
  • Duncan Armstrong
  • Carl J Balibar
  • Daniel Bauer
  • Cornelia Bellamacina
  • Bret M Benton
  • Dirksen Bussiere
  • Gianfranco De Pascale
  • Javier De Vicente
  • Charles R Dean
  • Bhavesh Dhumale
  • L Mark Fisher
  • John Fuller
  • Mangesh Fulsunder
  • Lauren M Holder
  • Cheng Hu
  • Bhavin Kantariya
  • Guillaume Lapointe
  • Jennifer A Leeds
  • Xiaolin Li
  • Peichao Lu
  • Anatoli Lvov
  • Sylvia Ma
  • Shravanthi Madhavan
  • Swapnil Malekar
  • David McKenney
  • Wosenu Mergo
  • Louis Metzger
  • Heinz E Moser
  • Daniel Mutnick
  • Jonas Noeske
  • Colin Osborne
  • Ashish Patel
  • Darshit Patel
  • Tushar Patel
  • Krunal Prajapati
  • Katherine R Prosen
  • Folkert Reck
  • Daryl L Richie
  • Alice Rico
  • Mark R Sanderson
  • Shailesh Satasia
  • William S Sawyer
  • Jogitha Selvarajah
  • Nirav Shah
  • Kartik Shanghavi
  • Wei Shu
  • Katherine V Thompson
  • Martin Traebert
  • Anand Vala
  • Lakhan Vala
  • Dennis A Veselkov
  • Jason Vo
  • Michael Wang
  • Marcella Widya
  • Sarah L Williams
  • Yongjin Xu
  • Qin Yue
  • Richard Zang
  • Bo Zhou
  • Alexey Rivkin
  • J. Med. Chem..2020 Jul;doi: 10.1021/acs.jmedchem.0c00347.Epub 2020-07-07.

酸化亜鉛ナノ化培地をグリーンに作製したことで、Panicum virgatum L.のカルス誘導と再生ダイナミクスが向上しました

Green fabricated zinc oxide nanoformulated media enhanced callus induction and regeneration dynamics of Panicum virgatum L.
  • Saima Shafique
  • Nyla Jabeen
  • Khawaja Shafique Ahmad
  • Samra Irum
  • Sadaf Anwaar
  • Naeem Ahmad
  • Sadia Alam
  • Muhammad Ilyas
  • Talha Farooq Khan
  • Syed Zaheer Hussain
  • PLoS ONE.2020;15(7):e0230464. PONE-D-20-05789. doi: 10.1371/journal.pone.0230464.Epub 2020-07-09.

多能性因子OCT4Aと標的遺伝子の複数の八量体モチーフとの細胞内文脈およびタンパク質レベル依存性の相互作用

Cellular context- and protein level-dependent interaction of pluripotency factor OCT4A with multiple octamer motifs of the same target gene.
  • Ning Zhou
  • Xiao-Bing Zhang
  • Cheng Chen
  • Xin-Yu Chen
  • Bo Kang
  • Jian-Qin He
  • Guo-Zhong Gong
  • Ying-Jie Wang
  • Yan-Wen Zhou
  • Life Sci..2020 May;248:117461. S0024-3205(20)30209-5. doi: 10.1016/j.lfs.2020.117461.Epub 2020-02-22.

FenestratedおよびBranched血管内動脈瘤修復術を受けた患者における脊髄損傷の危険因子と脳脊髄液ドレナージの合併症

Risk Factors for Spinal Cord Injury and Complications of Cerebrospinal Fluid Drainage in Patients Undergoing Fenestrated and Branched Endovascular Aneurysm Repair.
  • Napong Kitpanit
  • Sharif H Ellozy
  • Peter H Connolly
  • Christopher J Agrusa
  • Adam D Lichtman
  • Darren B Schneider
  • J. Vasc. Surg..2020 Jul;S0741-5214(20)31461-0. doi: 10.1016/j.jvs.2020.05.070.Epub 2020-07-05.

未熟な壊死性永久上顎中切歯の再生歯内療法における血小板リッチプラズマ(PRP)と血小板リッチフィブリン(PRF)足場の比較評価。二重盲検無作為化比較試験

Comparative evaluation of Platelet Rich Plasma (PRP) versus Platelet Rich Fibrin (PRF) scaffolds in regenerative endodontic treatment of immature necrotic permanent maxillary central incisors: A double blinded randomized controlled trial.
  • Hazim Mohamed Rizk
  • Mohamed Sherif Mohamed Salah Al-Deen
  • Asmaa Aly Emam
  • Saudi Dent J.2020 Jul;32(5):224-231. S1013-9052(19)30642-X. doi: 10.1016/j.sdentj.2019.09.002.Epub 2019-09-21.

ヒトの加齢は骨髄におけるCD34+造血細胞と脂肪細胞の間の空間構成を変化させる

Human Aging Alters the Spatial Organization between CD34+ Hematopoietic Cells and Adipocytes in Bone Marrow.
  • Alicia G Aguilar-Navarro
  • Berenice Meza-León
  • Dita Gratzinger
  • Fany G Juárez-Aguilar
  • Qing Chang
  • Olga Ornatsky
  • Hubert Tsui
  • Ricardo Esquivel-Gómez
  • Antonio Hernández-Ramírez
  • Stephanie Z Xie
  • John E Dick
  • Eugenia Flores-Figueroa
  • Stem Cell Reports.2020 Jun;S2213-6711(20)30232-0. doi: 10.1016/j.stemcr.2020.06.011.Epub 2020-06-26.

加齢に伴う記憶機能の予測:パターン補完能力と海馬活動は25年以上の視空間機能と関連している

Forecasting memory function in aging: pattern-completion ability and hippocampal activity relate to visuospatial functioning over 25 years.
  • Lars Nyberg
  • Xenia Grande
  • Micael Andersson
  • David Berron
  • Anders Lundquist
  • Mikael Stiernstedt
  • Anders Fjell
  • Kristine Walhovd
  • Greger Orädd
  • Neurobiol. Aging.2020 Jun;94:217-226. S0197-4580(20)30196-2. doi: 10.1016/j.neurobiolaging.2020.06.005.Epub 2020-06-12.

牛糞由来のリン酸活性炭ナノ材料を用いた再生可能エネルギー応用のためのフレキシブル型対称型スーパーキャパシタ電極の作製

Flexible Type Symmetric Supercapacitor Electrode Fabrication Using Phosphoric Acid-Activated Carbon Nanomaterials Derived from Cow Dung for Renewable Energy Applications.
  • Jothi Ramalingam Rajabathar
  • Manoharan Sivachidambaram
  • J Judith Vijaya
  • Hamad A Al-Lohedan
  • Dhaifallah M D Aldhayan
  • ACS Omega.2020 Jun;5(25):15028-15038. doi: 10.1021/acsomega.0c00848.Epub 2020-06-22.

電気化学バイオセンシングのための新規なアセテート機能化イオン液体/MWCNTマトリックス上にワサビペルオキシダーゼを固定化するための簡便な戦略

Facile strategy for immobilizing horseradish peroxidase on a novel acetate functionalized ionic liquid/MWCNT matrix for electrochemical biosensing.
  • K Theyagarajan
  • Mari Elancheziyan
  • Prakash Sinha Aayushi
  • Kathavarayan Thenmozhi
  • Int. J. Biol. Macromol..2020 Jul;S0141-8130(20)33748-X. doi: 10.1016/j.ijbiomac.2020.07.005.Epub 2020-07-04.

筋骨格系疼痛患者に対する非医療的トリアージ、自己紹介、ダイレクトアクセスサービスの系統的レビューとエビデンスの統合

A systematic review and evidence synthesis of non-medical triage, self-referral and direct access services for patients with musculoskeletal pain.
  • Opeyemi O Babatunde
  • Annette Bishop
  • Elizabeth Cottrell
  • Joanne L Jordan
  • Nadia Corp
  • Katrina Humphries
  • Tina Hadley-Barrows
  • Alyson L Huntley
  • Danielle A van der Windt
  • PLoS ONE.2020;15(7):e0235364. PONE-D-20-05712. doi: 10.1371/journal.pone.0235364.Epub 2020-07-06.

チエナマイシン生合成において、連続したラジカルS-アデノシルメチオニンのメチル化がエチル側鎖を形成する

Consecutive radical S-adenosylmethionine methylations form the ethyl side chain in thienamycin biosynthesis.
  • Daniel R Marous
  • Evan P Lloyd
  • Andrew R Buller
  • Kristos A Moshos
  • Tyler L Grove
  • Anthony J Blaszczyk
  • Squire J Booker
  • Craig A Townsend
  • Proc. Natl. Acad. Sci. U.S.A..2015 Aug;112(33):10354-8. 1508615112. doi: 10.1073/pnas.1508615112.Epub 2015-08-03.

遺伝情報を用いた脳内ネットワークの構造化パターンは、脳の表現型の個人差、行動、遺伝的決定、神経精神疾患の臨床結果と関連している可能性があります

Personalized connectome fingerprints: their importance in cognition from childhood to adult years.
  • B C Munsell
  • E Gleichgerrcht
  • E Hofesmann
  • J Delgaizo
  • C R McDonald
  • B Marebwa
  • M A Styner
  • J Fridriksson
  • C Rorden
  • N K Focke
  • J H Gilmore
  • L Bonilha
  • Neuroimage.2020 Jul;:117122. S1053-8119(20)30608-X. doi: 10.1016/j.neuroimage.2020.117122.Epub 2020-07-04.

先天性心疾患における吸気筋機能障害と制限的肺機能障害。免疫炎症反応や運動不耐性との関連

Inspiratory muscle dysfunction and restrictive lung function impairment in congenital heart disease: Association with immune inflammatory response and exercise intolerance.
  • Jens Spiesshoefer
  • Stefan Orwat
  • Carolin Henke
  • Hans-Joachim Kabitz
  • Stratis Katsianos
  • Chiara Borrelli
  • Helmut Baumgartner
  • Jerzy-Roch Nofer
  • Maximilian Spieker
  • Philipp Bengel
  • Alberto Giannoni
  • Michael Dreher
  • Matthias Boentert
  • Gerhard Paul Diller
  • Int. J. Cardiol..2020 Jul;S0167-5273(20)33433-1. doi: 10.1016/j.ijcard.2020.06.055.Epub 2020-07-04.

Microbispora hainanensis株CSR-4から単離された新規ジテルペン剤とそのアセチルコリンエステラーゼ酵素に対するインビトロおよびインシリコ阻害効果

A novel diterpene agent isolated from Microbispora hainanensis strain CSR-4 and its in vitro and in silico inhibition effects on acetylcholine esterase enzyme.
  • Chitti Thawai
  • Nantiya Bunbamrung
  • Pattama Pittayakhajonwut
  • Sumet Chongruchiroj
  • Jaturong Pratuangdejkul
  • Ya-Wen He
  • Sarin Tadtong
  • Vipaporn Sareedenchai
  • Pinidphon Prombutara
  • Yang Qian
  • Sci Rep.2020 Jul;10(1):11058. 10.1038/s41598-020-68009-y. doi: 10.1038/s41598-020-68009-y.Epub 2020-07-06.

また、緑膿菌のバイオフィルム形成に関与する応答調節因子GacAと転写活性化因子RhlRタンパク質は、天然のリード分子の有望なターゲットである。計算モデル化、分子ドッキング、動的シミュレーション研究

Response regulator GacA and transcriptional activator RhlR proteins involved in biofilm formation of Pseudomonas aeruginosa are prospective targets for natural lead molecules: Computational modelling, molecular docking and dynamic simulation studies.
  • Sinosh Skariyachan
  • Roshini Ravishankar
  • Dharshini Gopal
  • Aditi G Muddebihalkar
  • Akshay Uttarkar
  • Prinith Kaveramma Uluvangada Praveen
  • Vidya Niranjan
  • Infect. Genet. Evol..2020 Jul;85:104448. S1567-1348(20)30279-3. doi: 10.1016/j.meegid.2020.104448.Epub 2020-07-01.

免疫組織化学的手法を用いた結腸ポリープおよび結腸癌と診断されたスーダンの患者におけるヘリコバクター・ピロリの有病率

Prevalence of Helicobacter pylori among Sudanese patients diagnosed with colon polyps and colon cancer using immunohistochemistry technique.
  • Aziza K Mohamed
  • Nazik M Elhassan
  • Zahra A Awhag
  • Fadwa S Ali
  • Eman T Ali
  • Najwa A Mhmoud
  • Emmanuel E Siddig
  • Rowa Hassan
  • Eiman S Ahmed
  • Azam Fattahi
  • Ayman Ahmed
  • Mohamed S Muneer
  • Hussam A Osman
  • Nouh S Mohamed
  • Ali M M Edris
  • BMC Res Notes.2020 Jul;13(1):322. 10.1186/s13104-020-05159-2. doi: 10.1186/s13104-020-05159-2.Epub 2020-07-06.