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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

2020年07月 みんなが読んでいる論文

Porphyromonas gingivalisからのIX型分泌系の構成要素であるPorMの異なる構築物の結晶化シャペロンとして使用されたカメロイドナノボディ

Camelid nanobodies used as crystallization chaperones for different constructs of PorM, a component of the type IX secretion system from Porphyromonas gingivalis.
  • Yoan Duhoo
  • Jennifer Roche
  • Thi Trang Nhung Trinh
  • Aline Desmyter
  • Anaïs Gaubert
  • Christine Kellenberger
  • Christian Cambillau
  • Alain Roussel
  • Philippe Leone
  • Acta Crystallogr F Struct Biol Commun.2017 05;73(Pt 5):286-293. S2053230X17005969. doi: 10.1107/S2053230X17005969.Epub 2017-04-26.

線条体濃縮タンパク質チロシンホスファターゼシグナル伝達の破綻は、敗血症関連脳症のマウスモデルにおける記憶障害に寄与している可能性がある

Disruption of Striatal-Enriched Protein Tyrosine Phosphatase Signaling Might Contribute to Memory Impairment in a Mouse Model of Sepsis-Associated Encephalopathy.
  • Man-Man Zong
  • Hong-Mei Yuan
  • Xue He
  • Zhi-Qiang Zhou
  • Xiao-Dong Qiu
  • Jian-Jun Yang
  • Mu-Huo Ji
  • Neurochem. Res..2019 Dec;44(12):2832-2842. 10.1007/s11064-019-02905-2. doi: 10.1007/s11064-019-02905-2.Epub 2019-11-06.

HLA-A2に強い親和性を持つ合成腫瘍特異的抗原性ペプチドは、CD8 T細胞を活性化することで抗乳がん免疫応答を誘導します

Synthetic tumor-specific antigenic peptides with a strong affinity to HLA-A2 elicit anti-breast cancer immune response through activating CD8 T cells.
  • Wei Shi
  • Qianqian Qiu
  • Zhenzhen Tong
  • Weiwei Guo
  • Feng Zou
  • Ziying Feng
  • Yao Wang
  • Wenlong Huang
  • Hai Qian
  • Eur J Med Chem.2020 Mar;189:112051. S0223-5234(20)30018-0. doi: 10.1016/j.ejmech.2020.112051.Epub 2020-01-11.

全長腫瘍抗原mRNAをエレクトロポレーションした抗原提示型腫瘍細胞株を用いた腫瘍特異的T細胞受容体の機能性の迅速評価

Rapid Assessment of Functional Avidity of Tumor-Specific T Cell Receptors Using an Antigen-Presenting Tumor Cell Line Electroporated with Full-Length Tumor Antigen mRNA.
  • Diana Campillo-Davo
  • Maarten Versteven
  • Gils Roex
  • Hans De Reu
  • Sanne van der Heijden
  • Sébastien Anguille
  • Zwi N Berneman
  • Viggo F I Van Tendeloo
  • Eva Lion
  • Cancers (Basel).2020 Jan;12(2). E256. doi: 10.3390/cancers12020256.Epub 2020-01-21.

変形性膝関節症のヒト膝内側メニスカスの根元細胞と角細胞の細胞特性と機械的ストレスへの応答の違い

Differences between the root and horn cells of the human medial meniscus from the osteoarthritic knee in cellular characteristics and responses to mechanical stress.
  • Yuki Okazaki
  • Takayuki Furumatsu
  • Yusuke Kamatsuki
  • Keiichiro Nishida
  • Yoshihisa Nasu
  • Ryuichi Nakahara
  • Taichi Saito
  • Toshifumi Ozaki
  • J Orthop Sci.2020 Mar;S0949-2658(20)30067-1. doi: 10.1016/j.jos.2020.02.015.Epub 2020-03-26.

成人の肥満対策に対するマグネシウムサプリメントの効果:無作為化比較試験のシステマティックレビューと用量反応メタアナリシス

The effects of magnesium supplementation on obesity measures in adults: a systematic review and dose-response meta-analysis of randomized controlled trials.
  • Mohammadreza Askari
  • Hadis Mozaffari
  • Alireza Jafari
  • Mahtab Ghanbari
  • Manije Darooghegi Mofrad
  • Crit Rev Food Sci Nutr.2020 Jul;:1-17. doi: 10.1080/10408398.2020.1790498.Epub 2020-07-11.

運動はストレスを受けたラットの三叉神経後部核におけるCGRPの発現を増加させ、片頭痛に対する脆弱性を高めることが示唆された

Physical exercise enhances vulnerability to migraine headache associated with CGRP up-expression in trigeminal nucleus caudalis of stressed rats.
  • Razieh Kooshki
  • Mehdi Abbasnejad
  • Ali Shamsizadeh
  • Maryam Raoof
  • Khadijeh Askari-Zahabi
  • Saeed Esmaeili-Mahani
  • Neurol. Res..2020 Jul;:1-7. doi: 10.1080/01616412.2020.1794243.Epub 2020-07-18.

良い隣人、悪い隣人:海馬の頻繁なネットワーク近傍マッピングは、414人の被験者コホートにおける人間の知能のいくつかの構造的要因を明らかにした

Good neighbors, bad neighbors: the frequent network neighborhood mapping of the hippocampus enlightens several structural factors of the human intelligence on a 414-subject cohort.
  • Máté Fellner
  • Bálint Varga
  • Vince Grolmusz
  • Sci Rep.2020 Jul;10(1):11967. 10.1038/s41598-020-68914-2. doi: 10.1038/s41598-020-68914-2.Epub 2020-07-20.

ヒト病原性鉤虫Ancylostoma ceylanicumに対する駆虫活性のためのDalea parryi(マメ科)代謝物の調査

Investigation of Dalea parryi (Fabaceae) metabolites for anthelmintic activity against the human pathogenic hookworm Ancylostoma ceylanicum.
  • Gil Belofsky
  • Lindsay Engels
  • Victoria McPherson
  • Katherine Nash
  • Kiah Sullivan
  • Brendon Torrey
  • Cassandra Ripley
  • Angel Coria
  • Teresa Bicchieri
  • Blaise Dondji
  • Phytochemistry.2020 Jul;177:112423. S0031-9422(20)30143-6. doi: 10.1016/j.phytochem.2020.112423.Epub 2020-07-17.

ロシアにおける淡水産ムール貝(Unionidae)の統合的分類学、生物地理学、保全

Integrative taxonomy, biogeography and conservation of freshwater mussels (Unionidae) in Russia.
  • Ivan N Bolotov
  • Alexander V Kondakov
  • Ekaterina S Konopleva
  • Ilya V Vikhrev
  • Olga V Aksenova
  • Andrey S Aksenov
  • Yulia V Bespalaya
  • Alexey V Borovskoy
  • Petr P Danilov
  • Gennady A Dvoryankin
  • Mikhail Y Gofarov
  • Mikhail B Kabakov
  • Olga K Klishko
  • Yulia S Kolosova
  • Artem A Lyubas
  • Alexander P Novoselov
  • Dmitry M Palatov
  • Grigory N Savvinov
  • Nikolay M Solomonov
  • Vitaly M Spitsyn
  • Svetlana E Sokolova
  • Alena A Tomilova
  • Elsa Froufe
  • Arthur E Bogan
  • Manuel Lopes-Lima
  • Alexander A Makhrov
  • Maxim V Vinarski
  • Sci Rep.2020 Feb;10(1):3072. 10.1038/s41598-020-59867-7. doi: 10.1038/s41598-020-59867-7.Epub 2020-02-20.

模擬微小重力および過重力による心筋細胞のカルシウムシグナル伝達の変化

Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity.
  • Caizhi Liu
  • Guohui Zhong
  • Yuezhang Zhou
  • Yuchen Yang
  • Yingjun Tan
  • Yuheng Li
  • Xingcheng Gao
  • Weijia Sun
  • Jianwei Li
  • Xiaoyan Jin
  • Dengchao Cao
  • Xinxin Yuan
  • Zizhong Liu
  • Shuai Liang
  • Youyou Li
  • Ruikai Du
  • Yinlong Zhao
  • Jianqi Xue
  • Dingsheng Zhao
  • Jinping Song
  • Shukuan Ling
  • Yingxian Li
  • Cell Prolif..2020 Mar;53(3):e12783. doi: 10.1111/cpr.12783.Epub 2020-02-26.

空間的不確実性は、視覚的注意の分布を改善し、意識的な報告のための感覚情報の利用可能性を向上させる

Spatial uncertainty improves the distribution of visual attention and the availability of sensory information for conscious report.
  • Stefano Lasaponara
  • Mario Pinto
  • Michele Pellegrino
  • Ludovica Caratelli
  • Clelia Rossi-Arnaud
  • Vincenzo Cestari
  • Marco Costanzi
  • Fabrizio Doricchi
  • Exp Brain Res.2020 Jul;10.1007/s00221-020-05862-3. doi: 10.1007/s00221-020-05862-3.Epub 2020-07-02.

Limnospira indica PCC8005のフォトバイオリアクターでの成長:ISSと地上実験のモデルとシミュレーション

Limnospira indica PCC8005 growth in photobioreactor: model and simulation of the ISS and ground experiments.
  • Laurent Poughon
  • Céline Laroche
  • Catherine Creuly
  • Claude-Gilles Dussap
  • Christel Paille
  • Christophe Lasseur
  • Pieter Monsieurs
  • Wietse Heylen
  • Ilse Coninx
  • Felice Mastroleo
  • Natalie Leys
  • Life Sci Space Res (Amst).2020 May;25:53-65. S2214-5524(20)30015-8. doi: 10.1016/j.lssr.2020.03.002.Epub 2020-03-13.

将来の宇宙ミッションに向けた臨床試験の設計は、地球上での臨床試験の実施方法を変えるための道筋となる

Designing clinical trials for future space missions as a pathway to changing how clinical trials are conducted on Earth.
  • Mona Nasser
  • Nicholas Peres
  • Jacqui Knight
  • Agatha Haines
  • Charlie Young
  • Diego Maranan
  • Julian Wright
  • Philip Carvil
  • Karen Robinson
  • Matthew Westmore
  • Joanna Griffin
  • Matthew Halkes
  • J Evid Based Med.2020 May;13(2):153-160. doi: 10.1111/jebm.12391.Epub 2020-05-25.

嚢胞性線維症患者におけるキノロン代謝物の形成とクリアランスが健康なボランティアと比較して増加していることを示す最初の集団薬物動態解析

First population pharmacokinetic analysis showing increased quinolone metabolite formation and clearance in patients with cystic fibrosis compared to healthy volunteers.
  • Yuanyuan Jiao
  • Tae Hwan Kim
  • Xun Tao
  • Martina Kinzig
  • Cornelia B Landersdorfer
  • Stefanie K Drescher
  • Dhruvitkumar S Sutaria
  • Bartolome Moya
  • Ulrike Holzgrabe
  • Fritz Sörgel
  • Jürgen B Bulitta
  • Eur J Pharm Sci.2018 Oct;123:416-428. S0928-0987(18)30358-0. doi: 10.1016/j.ejps.2018.07.054.Epub 2018-08-01.

尋常性にきび治療におけるテトラサイクリン系抗生物質とスピロノラクトンの処方パターンを先進医療従事者と医師の間で比較分析した

Comparative analysis of prescribing patterns of tetracycline class antibiotics and spironolactone between advanced practice providers and physicians in the treatment of acne vulgaris.
  • Anthony K Guzman
  • John S Barbieri
  • J. Am. Acad. Dermatol..2020 Jun;S0190-9622(20)31141-5. doi: 10.1016/j.jaad.2020.06.044.Epub 2020-06-16.

耳鼻咽喉科医のための COVID-19 の最新情報 - 耳鼻咽喉科および頸部顔面外科(ABORL-CCF)のブラジル協会のポジションステートメント

An update on COVID-19 for the otorhinolaryngologist - a Brazilian Association of Otolaryngology and Cervicofacial Surgery (ABORL-CCF) Position Statement.
  • Joel Lavinsky
  • Eduardo Macoto Kosugi
  • Eduardo Baptistella
  • Renato Roithmann
  • Eduardo Dolci
  • Thais Knoll Ribeiro
  • Bruno Rossini
  • Fabrizio Ricci Romano
  • Rebecca Christina Kathleen Maunsell
  • Edson Ibrahim Mitre
  • Rui Imamura
  • Adriana Hachiya
  • Carlos Takahiro Chone
  • Luciana Miwa Nita Watanabe
  • Marco Aurélio Fornazieri
  • Marcus Miranda Lessa
  • Geraldo Druck Sant'Anna
  • Braz J Otorhinolaryngol.2020 May - Jun;86(3):273-280. S1808-8694(20)30037-9. doi: 10.1016/j.bjorl.2020.04.002.Epub 2020-04-11.

心臓外科手術患者における室温対体温での4%アルブミン500mLボーラスの血行動態と体温効果の比較

Comparison of the Hemodynamic and Temperature Effects of a 500-mL Bolus of 4% Albumin at Room Versus Body Temperature in Cardiac Surgery Patients.
  • Fumitaka Yanase
  • Laurent Bitker
  • Luca Lucchetta
  • Thummaporn Naorungroj
  • Salvatore L Cutuli
  • Eduardo A Osawa
  • Emmanuel Canet
  • Anthony Wilson
  • Glenn M Eastwood
  • Michael Bailey
  • Rinaldo Bellomo
  • J. Cardiothorac. Vasc. Anesth..2020 Jun;S1053-0770(20)30586-3. doi: 10.1053/j.jvca.2020.06.045.Epub 2020-06-18.

ラットの坐骨神経を慢性的に圧迫すると、脊髄の前角と後角でミクログリアの活性化モードが異なることが明らかになった

Chronic constriction injury of the sciatic nerve in rats causes different activation modes of microglia between the anterior and posterior horns of the spinal cord.
  • Tasuku Nishihara
  • Junya Tanaka
  • Keisuke Sekiya
  • Yuki Nishikawa
  • Naoki Abe
  • Taisuke Hamada
  • Sakiko Kitamura
  • Keizo Ikemune
  • Shinichiro Ochi
  • Mohammed E Choudhury
  • Hajime Yano
  • Toshihiro Yorozuya
  • Neurochem. Int..2020 03;134:104672. S0197-0186(19)30340-7. doi: 10.1016/j.neuint.2020.104672.Epub 2020-01-09.

ベナンの葉の抗酸化作用と酵素(A-アミラーゼ、B-グルコシダーゼ)阻害作用を探る

Exploring Antioxidant and Enzymes (A-Amylase and B-Glucosidase) Inhibitory Activity of and Leaves from Benin.
  • Michaelle Chokki
  • Mihaela Cudălbeanu
  • Cheikna Zongo
  • Durand Dah-Nouvlessounon
  • Ioana Otilia Ghinea
  • Bianca Furdui
  • Robert Raclea
  • Aly Savadogo
  • Lamine Baba-Moussa
  • Sorin Marius Avamescu
  • Rodica Mihaela Dinica
  • Farid Baba-Moussa
  • Foods.2020 Apr;9(4). E434. doi: 10.3390/foods9040434.Epub 2020-04-04.