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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

アジア人集団における動脈硬化性心血管病の二次予防のためのスタチン/エゼチミブの有効性。無作為化対照試験のシステマティックレビューとメタアナリシス

Efficacy of Statin/Ezetimibe for Secondary Prevention of Atherosclerotic Cardiovascular Disease in Asian Populations: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
  • Akshaya Srikanth Bhagavathula
  • Wafa Ali Aldhaleei
  • Nadya Obaid Al Matrooshi
  • Jamal Rahmani
  • Clin Drug Investig.2020 Jul;10.1007/s40261-020-00951-1. doi: 10.1007/s40261-020-00951-1.Epub 2020-07-15.

HLA遺伝子型と風邪薬誘発性Stevens-Johnson症候群/重度の眼合併症を伴う中毒性表皮壊死分解症:システマティックレビューとメタアナリシス

HLA genotypes and cold medicine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis with severe ocular complications: a systematic review and meta-analysis.
  • Wimonchat Tangamornsuksan
  • Sirikan Chanprasert
  • Phenphechaya Nadee
  • Saowalak Rungruang
  • Natnaree Meesilsat
  • Mayumi Ueta
  • Manupat Lohitnavy
  • Sci Rep.2020 Jun;10(1):10589. 10.1038/s41598-020-67610-5. doi: 10.1038/s41598-020-67610-5.Epub 2020-06-29.

マウスのシステイン/シスチンおよびグルタチオン/グルタチオンジスルフィド血漿酸化還元電位カップルに対する性、年齢および食事の影響

Impact of sex, age and diet on the cysteine/cystine and glutathione/glutathione disulfide plasma redox couples in mice.
  • Walter H Watson
  • John C Greenwell
  • Yuxuan Zheng
  • Stephen Furmanek
  • Edilson Torres-Gonzalez
  • Jeffrey D Ritzenthaler
  • Jesse Roman
  • J. Nutr. Biochem..2020 May;84:108431. S0955-2863(20)30463-0. doi: 10.1016/j.jnutbio.2020.108431.Epub 2020-05-24.

ベトナムのハイフォンでは、HIVコントロールプログラムによって薬物を注射した人のHIV発症率は減少するが、HCVの発症率は減少しない

HIV control programs reduce HIV incidence but not HCV incidence among people who inject drugs in HaiPhong, Vietnam.
  • Jean-Pierre Molès
  • Roselyne Vallo
  • Pham Minh Khue
  • Duong Thi Huong
  • Khuat Thi Hai Oanh
  • Nguyen Thi Thoa
  • Hoang Thi Giang
  • Nham Thi Tuyet Thanh
  • Vu Hai Vinh
  • Tuyet Anh Bui Thi
  • Marianne Peries
  • Kamyar Arasteh
  • Catherine Quillet
  • Jonathan Feelemyer
  • Laurent Michel
  • Don Des Jarlais
  • Didier Laureillard
  • Nicolas Nagot
  • Sci Rep.2020 Apr;10(1):6999. 10.1038/s41598-020-63990-w. doi: 10.1038/s41598-020-63990-w.Epub 2020-04-24.

茶植物におけるガロイル化カテキンの生合成に関与する酵素の進化と特徴付けのためのセリンカルボキシペプチダーゼ様アシルトランスフェラーゼ遺伝子ファミリーのゲノムワイド解析()

Genome-Wide Analysis of Serine Carboxypeptidase-Like Acyltransferase Gene Family for Evolution and Characterization of Enzymes Involved in the Biosynthesis of Galloylated Catechins in the Tea Plant ().
  • Muhammad Zulfiqar Ahmad
  • Penghui Li
  • Guangbiao She
  • Enhua Xia
  • Vagner A Benedito
  • Xiao Chun Wan
  • Jian Zhao
  • Front Plant Sci.2020;11:848. doi: 10.3389/fpls.2020.00848.Epub 2020-06-25.

軽度の認知機能障害を有するパーキンソン病における線条体ドーパミン神経細胞の完全性と認知機能障害および大脳皮質代謝との関連

Association of striatal dopaminergic neuronal integrity with cognitive dysfunction and cerebral cortical metabolism in Parkinson's disease with mild cognitive impairment.
  • Heeyoung Kim
  • Minyoung Oh
  • Jungsu S Oh
  • Hyojeong Moon
  • Sun Ju Chung
  • Chong Sik Lee
  • Jae Seung Kim
  • Nucl Med Commun.2019 Dec;40(12):1216-1223. doi: 10.1097/MNM.0000000000001098.

再発性/転移性頭頸部扁平上皮がんにおけるニボルマブ後のサルベージ化学療法の治療成績の予測におけるプログラム死リガンド1の役割

Role of programmed death-ligand 1 in predicting the treatment outcome of salvage chemotherapy after nivolumab in recurrent/metastatic head and neck squamous cell carcinoma.
  • Yushi Ueki
  • Takeshi Takahashi
  • Hisayuki Ota
  • Ryusuke Shodo
  • Keisuke Yamazaki
  • Arata Horii
  • Head Neck.2020 Jul;doi: 10.1002/hed.26374.Epub 2020-07-16.

低レベルレーザー光治療は骨格筋修復におけるI型およびIII型コラーゲンのリモデリングに影響を与える

Phototherapy with low-level laser affects the remodeling of types I and III collagen in skeletal muscle repair.
  • Thais Oricchio Fedri de Souza
  • Dayane Aparecida Mesquita
  • Raquel Agnelli Mesquita Ferrari
  • Décio Dos Santos Pinto
  • Luciana Correa
  • Sandra Kalil Bussadori
  • Kristianne Porta Santos Fernandes
  • Manoela Domingues Martins
  • Lasers Med Sci.2011 Nov;26(6):803-14. doi: 10.1007/s10103-011-0951-9.Epub 2011-07-15.

SMPD1遺伝子にp.L43_A44delLAのヘテロ接合変異を持つニーマン・ピック病B型患者からの誘導多能性幹細胞株(TRNDi004-I)の作製

Generation of an induced pluripotent stem cell line (TRNDi004-I) from a Niemann-Pick disease type B patient carrying a heterozygous mutation of p.L43_A44delLA in the SMPD1 gene.
  • Amanda Baskfield
  • Rong Li
  • Jeanette Beers
  • Jizhong Zou
  • Chengyu Liu
  • Wei Zheng
  • Stem Cell Res.2019 05;37:101436. S1873-5061(19)30066-2. doi: 10.1016/j.scr.2019.101436.Epub 2019-04-12.

クラウドベースのフリーエネルギー計算、合成を意識した列挙、目標指向の生成的機械学習を組み合わせて、大規模化学物質の迅速な探索と最適化を実現します

Combining Cloud-Based Free-Energy Calculations, Synthetically Aware Enumerations, and Goal-Directed Generative Machine Learning for Rapid Large-Scale Chemical Exploration and Optimization.
  • Phani Ghanakota
  • Pieter H Bos
  • Kyle D Konze
  • Joshua Staker
  • Gabriel Marques
  • Kyle Marshall
  • Karl Leswing
  • Robert Abel
  • Sathesh Bhat
  • J Chem Inf Model.2020 Jun;doi: 10.1021/acs.jcim.0c00120.Epub 2020-06-19.

欧州南東部諸国におけるアフリカ豚熱のリスク評価

Risk assessment of African swine fever in the south-eastern countries of Europe.
  • Søren Saxmose Nielsen
  • Julio Alvarez
  • Dominique Bicout
  • Paolo Calistri
  • Klaus Depner
  • Julian Ashley Drewe
  • Bruno Garin-Bastuji
  • Jose Luis Gonzales Rojas
  • Virginie Michel
  • Miguel Angel Miranda
  • Helen Roberts
  • Liisa Sihvonen
  • Hans Spoolder
  • Karl Ståhl
  • Arvo Viltrop
  • Christoph Winckler
  • Anette Boklund
  • Anette Bøtner
  • Jose Luis Gonzales Rojas
  • Simon J More
  • Hans-Hermann Thulke
  • Sotiria-Eleni Antoniou
  • José Cortinas Abrahantes
  • Sofie Dhollander
  • Andrey Gogin
  • Alexandra Papanikolaou
  • Laura C Gonzalez Villeta
  • Christian Gortázar Schmidt
  • EFSA J.2019 Nov;17(11):e05861. EFS25861. doi: 10.2903/j.efsa.2019.5861.Epub 2019-11-05.

PDGFRA変異GISTの遺伝子発現プロファイリングにより、D842Vエクソン18変異の特異的なフィンガープリントとしての免疫シグネチャーが明らかになった

Gene Expression Profiling of PDGFRA Mutant GIST Reveals Immune Signatures as a Specific Fingerprint of D842V Exon 18 Mutation.
  • Valentina Indio
  • Gloria Ravegnini
  • Annalisa Astolfi
  • Milena Urbini
  • Maristella Saponara
  • Antonio De Leo
  • Elisa Gruppioni
  • Giuseppe Tarantino
  • Sabrina Angelini
  • Andrea Pession
  • Maria Abbondanza Pantaleo
  • Margherita Nannini
  • Front Immunol.2020;11:851. doi: 10.3389/fimmu.2020.00851.Epub 2020-06-02.

心血管イベントを減少させるための米国食品医薬品局(FDA)の適応拡大に伴う抗高血糖薬の使用。学術医療センター内での処方パターン

Antihyperglycemic Therapies with Expansions of US Food and Drug Administration Indications to Reduce Cardiovascular Events: Prescribing Patterns within an Academic Medical Center.
  • Arsalan Hamid
  • Muthiah Vaduganathan
  • Adebamike Oshunbade
  • Krishna K Ayyalasomayajula
  • Andreas P Kalogeropoulos
  • Lillian F Lien
  • Tariq Shafi
  • Michael Hall
  • Javed Butler
  • J. Cardiovasc. Pharmacol..2020 Jun;doi: 10.1097/FJC.0000000000000864.Epub 2020-06-17.

重症再生不良性貧血に対してシクロスポリンとレバミソールを交互に併用した新規免疫抑制療法の長期追跡調査を行った

Long-term follow-up of a novel immunosuppressive strategy of cyclosporine alternatively combined with levamisole for severe aplastic anemia.
  • Jiali Huo
  • Xingxin Li
  • Yingqi Shao
  • Xiang Ren
  • Meili Ge
  • Yahong You
  • Jinbo Huang
  • Jing Zhang
  • Min Wang
  • Neng Nie
  • Peng Jin
  • Yizhou Zheng
  • Ann. Hematol..2020 Aug;99(8):1727-1734. 10.1007/s00277-020-04153-9. doi: 10.1007/s00277-020-04153-9.Epub 2020-06-29.

1997年から2017年までのサハラ以南のアフリカにおけるマラリア対策のための屋内残留噴霧:調整済みレトロスペクティブ分析

Indoor residual spraying for malaria control in sub-Saharan Africa 1997 to 2017: an adjusted retrospective analysis.
  • Julie-Anne A Tangena
  • Chantal M J Hendriks
  • Maria Devine
  • Meghan Tammaro
  • Anna E Trett
  • Ignatius Williams
  • Adilson José DePina
  • Achamylesh Sisay
  • Ramandimbiarijaona Herizo
  • Hmooda Toto Kafy
  • Elizabeth Chizema
  • Allan Were
  • Jennifer Rozier
  • Michael Coleman
  • Catherine L Moyes
  • Malar. J..2020 Apr;19(1):150. 10.1186/s12936-020-03216-6. doi: 10.1186/s12936-020-03216-6.Epub 2020-04-10.

1990年から2017年までのBRICS諸国における身体リハビリテーションのニーズ.世界疾病負担調査のデータを用いた国をまたいだ分析

Physical Rehabilitation Needs in the BRICS Nations from 1990 to 2017: Cross-National Analyses Using Data from the Global Burden of Disease Study.
  • Tiago S Jesus
  • Michel D Landry
  • Helen Hoenig
  • Yi Zeng
  • Sureshkumar Kamalakannan
  • Raquel R Britto
  • Nana Pogosova
  • Olga Sokolova
  • Karen Grimmer
  • Quinette A Louw
  • Int J Environ Res Public Health.2020 Jun;17(11). E4139. doi: 10.3390/ijerph17114139.Epub 2020-06-10.

子宮筋腫に対する超音波ガイド下高強度集束超音波(USgHIFU)アブレーションと腹腔鏡下子宮筋腫切除術の妊娠転帰の比較:比較研究

A comparison of the pregnancy outcomes between ultrasound-guided high-intensity focused ultrasound ablation and laparoscopic myomectomy for uterine fibroids: a comparative study.
  • Guangping Wu
  • Rong Li
  • Min He
  • Yuanfang Pu
  • Jishu Wang
  • Jinyun Chen
  • Hongbo Qi
  • Int J Hyperthermia.2020;37(1):617-623. doi: 10.1080/02656736.2020.1774081.

頭頸部扁平上皮癌の再発性または転移性頭頸部扁平上皮癌を対象としたTalimogene LaherparepvecとPembrolizumabの併用療法(MASTERKEY-232)。多施設共同第1b相試験

Talimogene Laherparepvec and Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY-232): A Multicenter, Phase 1b Study.
  • Kevin J Harrington
  • Anthony Kong
  • Nicolas Mach
  • Jason Chesney
  • Beatriz Castelo Fernandez
  • Danny Rischin
  • Ezra E W Cohen
  • Hoi-Shen Radcliffe
  • Burak Gumuscu
  • Jonathan Cheng
  • Wendy Snyder
  • Lillian L Siu
  • Clin. Cancer Res..2020 Jul;clincanres.1170.2020. doi: 10.1158/1078-0432.CCR-20-1170.Epub 2020-07-15.

爪真菌症の治療におけるフラクショナル2940nm Er:YAGレーザーと5%アモロルフィンラッカーの併用療法と5%アモロルフィンラッカー単剤療法の比較:無作為化比較試験

Comparison of a fractional 2940-nm Er:YAG laser and 5% amorolfine lacquer combination therapy versus a 5% amorolfine lacquer monotherapy for the treatment of onychomycosis: a randomized controlled trial.
  • Jing Zhang
  • Yunqing Zhang
  • Jinglin Qin
  • Sha Lu
  • Wenying Cai
  • Jiahao Li
  • Huaiqiu Huang
  • Sulian Yang
  • Liyan Xi
  • Lasers Med Sci.2020 Jun;10.1007/s10103-020-03054-7. doi: 10.1007/s10103-020-03054-7.Epub 2020-06-17.

喘息患者および健康な個体における家畜農場からの粒子状物質に対する生体外自然応答

Ex vivo innate responses to particulate matter from livestock farms in asthma patients and healthy individuals.
  • Linsey E S de Groot
  • Dingyu Liu
  • Barbara S Dierdorp
  • Niki Fens
  • Marianne A van de Pol
  • Peter J Sterk
  • Wim Kulik
  • Miriam E Gerlofs-Nijland
  • Flemming R Cassee
  • Elena Pinelli
  • René Lutter
  • Environ Health.2020 Jul;19(1):78. 10.1186/s12940-020-00632-8. doi: 10.1186/s12940-020-00632-8.Epub 2020-07-03.

マダガスカルの白亜紀哺乳類の骨格は長期的な不規則性を反映している

Skeleton of a Cretaceous mammal from Madagascar reflects long-term insularity.
  • David W Krause
  • Simone Hoffmann
  • Yaoming Hu
  • John R Wible
  • Guillermo W Rougier
  • E Christopher Kirk
  • Joseph R Groenke
  • Raymond R Rogers
  • James B Rossie
  • Julia A Schultz
  • Alistair R Evans
  • Wighart von Koenigswald
  • Lydia J Rahantarisoa
  • Nature.2020 05;581(7809):421-427. 10.1038/s41586-020-2234-8. doi: 10.1038/s41586-020-2234-8.Epub 2020-04-29.

イネ科コイの遺伝子型II型イネ科レオウイルス感染後の臨床症状,ウイルス分布,抗ウイルス免疫関連遺伝子のmRNA発現に関する研究

Studies on the clinical symptoms, virus distribution, and mRNA expression of several antiviral immunity-related genes in grass carp after infection with genotype II grass carp reovirus.
  • Minglin Wu
  • Haiyang Li
  • Xiaowu Chen
  • Yangyang Jiang
  • Wei Jiang
  • Arch. Virol..2020 Jul;165(7):1599-1609. 10.1007/s00705-020-04654-y. doi: 10.1007/s00705-020-04654-y.Epub 2020-05-12.

早漏、その診断とフォルタシンスプレーによる局所治療に対する認識、期待、嗜好、態度。専門家パネルディスカッションの結果

Perceptions, Expectations, Preferences, and Attitudes Toward Premature Ejaculation, Its Diagnosis and Topical Treatment with Fortacin™ Spray: Results from an Expert Panel Discussion.
  • Ferdinando Fusco
  • Massimiliano Creta
  • Francesco Mangiapia
  • Lorenzo Cirigliano
  • Francesco Trama
  • Savio Domenico Pandolfo
  • Ciro Imbimbo
  • Nicola Longo
  • Vincenzo Mirone
  • Res Rep Urol.2020;12:211-216. 250301. doi: 10.2147/RRU.S250301.Epub 2020-07-02.

制御されたドキソルビシン送達のための磁気共鳴活性化可能な熱感受性リポソーム

Magnetic resonance activatable thermosensitive liposomes for controlled doxorubicin delivery.
  • Mohamad Alawak
  • Gihan Mahmoud
  • Alice Abu Dayyih
  • Lili Duse
  • Shashank Reddy Pinnapireddy
  • Konrad Engelhardt
  • Ibrahim Awak
  • Christian Wölk
  • Alexander M König
  • Jana Brüßler
  • Udo Bakowsky
  • Mater Sci Eng C Mater Biol Appl.2020 Oct;115:111116. S0928-4931(20)30616-0. doi: 10.1016/j.msec.2020.111116.Epub 2020-05-25.

オーストラリア、ビクトリア州の公立病院における難民背景を持つ女性のための妊産婦ケアへのアクセスを改善するためのシステム改革の評価。中断された時系列のデザイン

Evaluation of systems reform in public hospitals, Victoria, Australia, to improve access to antenatal care for women of refugee background: An interrupted time series design.
  • Jane Yelland
  • Fiona Mensah
  • Elisha Riggs
  • Ellie McDonald
  • Josef Szwarc
  • Wendy Dawson
  • Dannielle Vanpraag
  • Sue Casey
  • Christine East
  • Mary Anne Biro
  • Glyn Teale
  • Sue Willey
  • Stephanie J Brown
  • PLoS Med..2020 Jul;17(7):e1003089. PMEDICINE-D-19-03494. doi: 10.1371/journal.pmed.1003089.Epub 2020-07-10.

脳性麻痺患者の下肢痙縮の治療におけるボツリヌス毒素A型注射と比較した放射状体外衝撃波治療の有効性。無作為化対照クロスオーバー試験

Efficacy of radial extracorporeal shock wave therapy compared with botulinum toxin type A injection in treatment of lower extremity spasticity in subjects with cerebral palsy: A randomized, controlled, cross-over study.
  • Xavier Vidal
  • Joan Martí-Fàbregas
  • Olga Canet
  • Marta Roqué
  • Antoni Morral
  • Miriam Tur
  • Christoph Schmitz
  • Mercè Sitjà-Rabert
  • J Rehabil Med.2020 Jun;52(6):jrm00076. doi: 10.2340/16501977-2703.Epub 2020-06-30.

脳内浸透型のPQR620 mTORとPQR530 PI3K/mTOR阻害剤はHDの細胞モデルにおけるハンチントン病レベルを低下させる

Brain-penetrant PQR620 mTOR and PQR530 PI3K/mTOR inhibitor reduce huntingtin levels in cell models of HD.
  • Elisabeth Singer
  • Carolin Walter
  • Doriano Fabbro
  • Denise Rageot
  • Florent Beaufils
  • Matthias P Wymann
  • Nadine Rischert
  • Olaf Riess
  • Petra Hillmann
  • Huu Phuc Nguyen
  • Neuropharmacology.2020 01;162:107812. S0028-3908(19)30379-X. doi: 10.1016/j.neuropharm.2019.107812.Epub 2019-10-14.

ブラジルにおける非妊娠女性を対象とした活動性梅毒に対するセフィキシムの臨床効果を評価する第 II 相試験(CeBra)

Phase II trial evaluating the clinical efficacy of cefixime for treatment of active syphilis in non-pregnant women in Brazil (CeBra).
  • Melanie M Taylor
  • Edna Oliveira Kara
  • Maria Alix Leite Araujo
  • Mariangela Freitas Silveira
  • Angelica Espinosa Miranda
  • Ivo Castelo Branco Coelho
  • Maria Luiza Bazzo
  • Gerson Fernando Mendes Pereira
  • Silvana Pereira Giozza
  • Ximena Pamela Díaz Bermudez
  • Maeve B Mello
  • Ndema Habib
  • My Huong Nguyen
  • Soe Soe Thwin
  • Nathalie Broutet
  • BMC Infect. Dis..2020 Jun;20(1):405. 10.1186/s12879-020-04980-1. doi: 10.1186/s12879-020-04980-1.Epub 2020-06-10.

T2および拡散強調MRIを用いた子宮頸癌における体積の描出。オブザーバー間の体積の一致

Volume Delineation in Cervical Cancer With T2 and Diffusion-weighted MRI: Agreement on Volumes Between Observers.
  • Consuelo Rosa
  • Andrea Delli Pizzi
  • Antonietta Augurio
  • Luciana Caravatta
  • Monica DI Tommaso
  • Erica Mincuzzi
  • Sebastiano Cinalli
  • Raffaella Basilico
  • Annamaria Porreca
  • Marta DI Nicola
  • Domenico Genovesi
  • In Vivo.2020 Jul-Aug;34(4):1981-1986. 34/4/1981. doi: 10.21873/invivo.11995.

再建手術を受けている乳がん患者に対するマッサージとマッサージプラス鍼治療との比較

Massage Compared with Massage Plus Acupuncture for Breast Cancer Patients Undergoing Reconstructive Surgery.
  • Christina A Dilaveri
  • Ivana T Croghan
  • Molly J Mallory
  • Liza J Dion
  • Karen M Fischer
  • Darrell R Schroeder
  • Jorys Martinez-Jorge
  • Minh-Doan T Nguyen
  • Shawn C Fokken
  • Brent A Bauer
  • Dietlind L Wahner-Roedler
  • J Altern Complement Med.2020 Jul;26(7):602-609. doi: 10.1089/acm.2019.0479.

アルツハイマー病における神経炎症メカニズムの精密医療への道

A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease.
  • Harald Hampel
  • Filippo Caraci
  • A Claudio Cuello
  • Giuseppe Caruso
  • Robert Nisticò
  • Massimo Corbo
  • Filippo Baldacci
  • Nicola Toschi
  • Francesco Garaci
  • Patrizia A Chiesa
  • Steven R Verdooner
  • Leyla Akman-Anderson
  • Félix Hernández
  • Jesús Ávila
  • Enzo Emanuele
  • Pedro L Valenzuela
  • Alejandro Lucía
  • Mark Watling
  • Bruno P Imbimbo
  • Andrea Vergallo
  • Simone Lista
  • Front Immunol.2020;11:456. doi: 10.3389/fimmu.2020.00456.Epub 2020-03-31.

帯状疱疹と認知症との関連性と抗ウイルス療法の認知症リスクへの効果:集団ベースのコホート研究

Association of herpes zoster with dementia and effect of antiviral therapy on dementia: a population-based cohort study.
  • Seongman Bae
  • Sung-Cheol Yun
  • Min-Chul Kim
  • Woon Yoon
  • Joon Seo Lim
  • Sang-Oh Lee
  • Sang-Ho Choi
  • Yang Soo Kim
  • Jun Hee Woo
  • Seong Yoon Kim
  • Sung-Han Kim
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再治療の長期フォローアップとアウトカム転移性去勢抵抗性前立腺癌におけるルテチウム-177(Lu)PSMA-617療法の拡張50患者単施設第II相前向き試験における再治療の長期フォローアップとアウトカム

Re: Long Term Follow-Up and Outcomes of Re-Treatment in an Expanded 50 Patient Single-Center Phase II Prospective Trial of Lutetium-177 (Lu) PSMA-617 Theranostics in Metastatic Castrate-Resistant Prostate Cancer.
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ホルモン受容体陽性/HER2陰性の早期乳癌患者における、免疫組織化学的に定義された腔状サブタイプに応じた用量密度の高い補助化学療法の効果:GIM2試験の探索的解析

Effect of dose-dense adjuvant chemotherapy in hormone receptor positive/HER2-negative early breast cancer patients according to immunohistochemically defined luminal subtype: an exploratory analysis of the GIM2 trial.
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  • Cecilia Nisticò
  • Sabino De Placido
  • Ornella Garrone
  • Teresa Gamucci
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高齢マウスにアジュバント組換えインフルエンザ核タンパク質をワクチン接種すると,防御免疫が増強される.

Vaccination of aged mice with adjuvanted recombinant influenza nucleoprotein enhances protective immunity.
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小児小脳悪性腫瘍の治療を目的とした抗がん剤HSV G207のヒト初の第1相免疫療法臨床試験のデザインと根拠

Design and Rationale for First-In-Human Phase 1 Immunovirotherapy Clinical Trial of Oncolytic HSV G207 to Treat Malignant Pediatric Cerebellar Brain Tumors.
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マンソン病の免疫調節分子Sm16/SPO-1/SmSLPは、トレマトード特異的な蠕虫防御分子(HDM)の一種です

Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs).
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DL-3-n-ブチルフタル酸は,大脳動脈硬化性狭窄症患者における脳血流低下を改善する:単施設,無作為化,二重盲検,プラセボ対照試験

DL-3-n-butylphthalide improves cerebral hypoperfusion in patients with large cerebral atherosclerotic stenosis: a single-center, randomized, double-blind, placebo-controlled study.
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思春期の若者におけるうつ病とモバイルテクノロジーやソーシャルメディアの利用との関係:アンブレラレビュー

Relationship between depression and the use of mobile technologies and social media among adolescents: an umbrella review.
  • Jorge Arias-de la Torre
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  • Xavier Garcia
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  • Tania Fernandez-Villa
  • Antonio J Molina
  • Vicente Martin
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  • Mireia Espallargues
  • J. Med. Internet Res..2020 Jun;doi: 10.2196/16388.Epub 2020-06-03.

雌のアフリカ産コメ癭蝿(Orseolia oryzivora Harris and Gagné)の電気生理学的・行動学的反応と宿主植物の揮発性物質に対する反応

Electrophysiological and behavioral responses of female African rice gall midge, Orseolia oryzivora Harris and Gagné, to host plant volatiles.
  • Emmanuel O Ogah
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  • John C Caulfield
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  • Francis E Nwilene
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声帯瘢痕および声帯溝に対する組換え肝細胞増殖因子を用いた耳内注射の第I/II相探索的臨床試験

A phase I/II exploratory clinical trial for intracordal injection of recombinant hepatocyte growth factor for vocal fold scar and sulcus.
  • Shigeru Hirano
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  • Masanobu Mizuta
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  • Nao Hiwatashi
  • Yoshitaka Kawai
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ボトリosphaeranは、Walker-256 腫瘍担持肥満ラットにおける腫瘍の発生と癌性悪液質症候群を減衰させ、これらのラットの代謝学的および血液学的プロフィールを改善する

Botryosphaeran Attenuates Tumor Development and the Cancer Cachexia Syndrome in Walker-256 Tumor-Bearing Obese Rats and Improves the Metabolic and Hematological Profiles of These Rats.
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TRPV4はミトコンドリアの輸送を阻害し、CaMKIIに依存した細胞内Caの上昇を介して軸索変性を引き起こす

TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca.
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CD74アイソフォームが41kDaに存在しないことで、ヒト肺腺癌由来細胞におけるCD74とCD44の異型関連が抑制される

Absence of CD74 Isoform at 41kDa Prevents the Heterotypic Associations between CD74 and CD44 in Human Lung Adenocarcinoma-derived Cells.
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潰瘍性大腸炎患者の実世界コホートにおけるトファシチニブの安全性

Safety of Tofacitinib in a Real-World Cohort of Patients With Ulcerative Colitis.
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