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日本語AIでPubMedを検索

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日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
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みんなが読んでいる論文

四面体DNAナノ構造体をベースとした多機能複合体の設計、作製、およびドラッグデリバリーおよび生物医学的治療への応用

Design, fabrication and applications of tetrahedral DNA nanostructure-based multifunctional complexes in drug delivery and biomedical treatment.
  • Tao Zhang
  • Taoran Tian
  • Ronghui Zhou
  • Songhang Li
  • Wenjuan Ma
  • Yuxin Zhang
  • Nanxin Liu
  • Sirong Shi
  • Qianshun Li
  • Xueping Xie
  • Yichen Ge
  • Mengting Liu
  • Qi Zhang
  • Shiyu Lin
  • Xiaoxiao Cai
  • Yunfeng Lin
  • Nat Protoc.2020 Jul;10.1038/s41596-020-0355-z. doi: 10.1038/s41596-020-0355-z.Epub 2020-07-15.

ジンバブエにおける多剤耐性およびリファンピシン耐性結核の治療成績：2010年から2015年の間に治療を開始した患者のコホート解析

Treatment outcomes of multi drug resistant and rifampicin resistant Tuberculosis in Zimbabwe: A cohort analysis of patients initiated on treatment during 2010 to 2015.
  • Ronnie Matambo
  • Kudakwashe C Takarinda
  • Pruthu Thekkur
  • Charles Sandy
  • Sungano Mharakurwa
  • Talent Makoni
  • Ronald Ncube
  • Kelvin Charambira
  • Christopher Zishiri
  • Mkhokheli Ngwenya
  • Saziso Nyathi
  • Albert Chiteka
  • Elliot Chikaka
  • Shungu Mutero-Munyati
  • PLoS ONE.2020;15(4):e0230848. PONE-D-19-16150. doi: 10.1371/journal.pone.0230848.Epub 2020-04-30.

多剤耐性結核患者における体格指数の変化のプロファイルの違い：レトロスペクティブコホート研究

Different profiles of body mass index variation among patients with multidrug-resistant tuberculosis: a retrospective cohort study.
  • Alhassane Diallo
  • Boubacar Djelo Diallo
  • Lansana Mady Camara
  • Lucrèce Ahouéfa Nadège Kounoudji
  • Boubacar Bah
  • Fulgence N'Zabintawali
  • Miguel Carlos-Bolumbu
  • Mamadou Hassimiou Diallo
  • Oumou Younoussa Sow
  • BMC Infect. Dis..2020 Apr;20(1):315. 10.1186/s12879-020-05028-0. doi: 10.1186/s12879-020-05028-0.Epub 2020-04-28.

RECIST 1.1、irRC、iRECIST基準に基づく半自動ソフトウェアによる免疫療法の奏効評価：主観的評価との比較

Response evaluation for immunotherapy through semi-automatic software based on RECIST 1.1, irRC, and iRECIST criteria: comparison with subjective assessment.
  • Ying-Chieh Lai
  • Wen-Cheng Chang
  • Chun-Bing Chen
  • Chi-Liang Wang
  • Yu-Fen Lin
  • Ming-Mo Ho
  • Chi-Yuan Cheng
  • Pei-Wei Huang
  • Chao-Wei Hsu
  • Gigin Lin
  • Acta Radiol.2020 Jul;61(7):983-991. doi: 10.1177/0284185119887588.Epub 2019-11-18.

高齢の非小細胞肺がん患者におけるプラチナ製剤ベースの化学療法。現実の世界で何を期待すべきか

Platinum-Based Chemotherapy in Older Patients with Non-Small Cell Lung Cancer: What to Expect in the Real World.
  • Giacomo Pelizzari
  • Francesco Cortiula
  • Marco Giavarra
  • Michele Bartoletti
  • Camilla Lisanti
  • Vanessa Buoro
  • Monica Cattaneo
  • Ciro Rossetto
  • Simona Rizzato
  • Fabio Puglisi
  • Marianna Macerelli
  • Gianpiero Fasola
  • Alessandro Follador
  • Drugs Aging.2020 Jul;10.1007/s40266-020-00785-8. doi: 10.1007/s40266-020-00785-8.Epub 2020-07-17.

発達期Wntシグナル伝達経路エフェクターβ-カテニン/TCFは、脂質代謝を調節する性ホルモンエストラジオールの肝機能を媒介している

The developmental Wnt signaling pathway effector β-catenin/TCF mediates hepatic functions of the sex hormone estradiol in regulating lipid metabolism.
  • Lili Tian
  • Weijuan Shao
  • Wilfred Ip
  • Zhuolun Song
  • Yasaman Badakhshi
  • Tianru Jin
  • PLoS Biol..2019 10;17(10):e3000444. PBIOLOGY-D-19-01324. doi: 10.1371/journal.pbio.3000444.Epub 2019-10-07.

新興汚染物質除去のための代替バイオプロセスに関するレビュー

A review on alternative bioprocesses for removal of emerging contaminants.
  • Aline Viancelli
  • William Michelon
  • Paula Rogovski
  • Rafael Dorighello Cadamuro
  • Estêvão Brasiliense de Souza
  • Gislaine Fongaro
  • Aline Frumi Camargo
  • Fábio Sptiza Stefanski
  • Bruno Venturin
  • Thamarys Scapini
  • Charline Bonatto
  • Karina Paula Preczeski
  • Natalia Klanovicz
  • Débora de Oliveira
  • Helen Treichel
  • Bioprocess Biosyst Eng.2020 Jul;10.1007/s00449-020-02410-9. doi: 10.1007/s00449-020-02410-9.Epub 2020-07-17.

PTSD治療のためのMDMA支援心理療法の長期追跡調査結果：6つの第2相試験の縦断的プール解析

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials.
  • Lisa Jerome
  • Allison A Feduccia
  • Julie B Wang
  • Scott Hamilton
  • Berra Yazar-Klosinski
  • Amy Emerson
  • Michael C Mithoefer
  • Rick Doblin
  • Psychopharmacology (Berl.).2020 Aug;237(8):2485-2497. 10.1007/s00213-020-05548-2. doi: 10.1007/s00213-020-05548-2.Epub 2020-06-04.

ヨーロッパ産ガラスウナギ(Anguilla anguilla)の行動とエネルギー関連遺伝子の転写反応にメチル水銀の新たな知見を得た

New insights into methylmercury induced behavioral and energy-related gene transcriptional responses in European glass eel (Anguilla anguilla).
  • Hengtong Liu
  • Amaia Lamarins
  • Jacques Labonne
  • Mathilde Monperrus
  • Pascale Coste
  • Emmanuel Huchet
  • Jacques Rives
  • Iban Seiliez
  • Valérie Bolliet
  • Chemosphere.2020 Sep;255:127020. S0045-6535(20)31213-3. doi: 10.1016/j.chemosphere.2020.127020.Epub 2020-05-10.

新生児のセボフルラン曝露は、その後のセボフルラン曝露の副作用に対する脆弱性の窓を広げ、デシタビン感受性機序を介して海馬の形態を変化させる

Neonatal exposure to sevoflurane expands the window of vulnerability to adverse effects of subsequent exposure to sevoflurane and alters hippocampal morphology via decitabine-sensitive mechanisms.
  • Yunan Lin
  • Lei Lei
  • Ling-Sha Ju
  • Ning Xu
  • Timothy E Morey
  • Nikolaus Gravenstein
  • Jianjun Yang
  • Anatoly E Martynyuk
  • Neurosci. Lett..2020 Jul;735:135240. S0304-3940(20)30510-3. doi: 10.1016/j.neulet.2020.135240.Epub 2020-07-07.

早期ホルモン陽性乳癌の女性における手術選択とその後の患者報告満足度の転帰との関係における人種差

Racial differences in the relationship between surgical choice and subsequent patient-reported satisfaction outcomes among women with early-stage hormone-positive breast cancer.
  • Prudvi Arabandi
  • Alexander N Slade
  • Arnethea L Sutton
  • Kandace P McGuire
  • Vanessa Sheppard
  • Breast Cancer Res. Treat..2020 Jul;10.1007/s10549-020-05784-2. doi: 10.1007/s10549-020-05784-2.Epub 2020-07-16.

p32/C1QBPは、ミトコンドリアの機能不全やアポトーシスに関連するミトコンドリアの連結性を維持するために、OMA1依存性のタンパク質分解処理を制御しています

p32/C1QBP regulates OMA1-dependent proteolytic processing of OPA1 to maintain mitochondrial connectivity related to mitochondrial dysfunction and apoptosis.
  • Solhee Noh
  • Sophors Phorl
  • Rema Naskar
  • Kakada Oeum
  • Yuri Seo
  • Eunjung Kim
  • Hee-Seok Kweon
  • Joo-Yong Lee
  • Sci Rep.2020 Jun;10(1):10618. 10.1038/s41598-020-67457-w. doi: 10.1038/s41598-020-67457-w.Epub 2020-06-30.

手術不能な慢性血栓塞栓性肺高血圧症に対するバルーン肺血管形成術：英国での経験

Balloon pulmonary angioplasty for inoperable chronic thromboembolic pulmonary hypertension: the UK experience.
  • Stephen P Hoole
  • John G Coghlan
  • John E Cannon
  • Dolores Taboada
  • Mark Toshner
  • Karen Sheares
  • Andrew John Fletcher
  • Guillermo Martinez
  • Alessandro Ruggiero
  • Nicholas Screaton
  • David Jenkins
  • Joanna Pepke-Zaba
  • Open Heart.2020;7(1):e001144. openhrt-2019-001144. doi: 10.1136/openhrt-2019-001144.Epub 2020-02-27.

胚性幹細胞由来心筋細胞における成熟心室サブタイプの優位性が生体内で増加している

Increased predominance of the matured ventricular subtype in embryonic stem cell-derived cardiomyocytes in vivo.
  • Hajime Ichimura
  • Shin Kadota
  • Toshihide Kashihara
  • Mitsuhiko Yamada
  • Kuniaki Ito
  • Hideki Kobayashi
  • Yuki Tanaka
  • Naoko Shiba
  • Shinichiro Chuma
  • Shugo Tohyama
  • Tatsuichiro Seto
  • Kenji Okada
  • Koichiro Kuwahara
  • Yuji Shiba
  • Sci Rep.2020 Jul;10(1):11883. 10.1038/s41598-020-68373-9. doi: 10.1038/s41598-020-68373-9.Epub 2020-07-17.

資源が限られた環境下で、初期の臨床的特徴と検査的特徴を用いて、重症化リスクの高いデング熱患者を同定すること

Identification of dengue patients with high risk of severe disease, using early clinical and laboratory features, in a resource-limited setting.
  • Madunil A Niriella
  • Isurujith K Liyanage
  • Arundathi Udeshika
  • Kasun V Liyanapathirana
  • Arjuna P De Silva
  • Hithnadura J de Silva
  • Arch. Virol..2020 Jul;10.1007/s00705-020-04720-5. doi: 10.1007/s00705-020-04720-5.Epub 2020-07-02.

ジカの時代における希望と信頼：ブラジルにおける流行の最前線にいる介護者と医療従事者の見解

Hope and trust in times of Zika: the views of caregivers and healthcare workers at the forefront of the epidemic in Brazil.
  • Clarissa Simas
  • Loveday Penn-Kekana
  • Hannah Kuper
  • Tereza Maciel Lyra
  • Maria Elisabeth Lopes Moreira
  • Maria do Socorro Veloso de Albuquerque
  • Thália Velho Barreto de Araújo
  • Ana Paula Lopes de Melo
  • Corina Helena Figueira Mendes
  • Martha Cristina Nunes Moreira
  • Marcos Antonio Ferreira do Nascimento
  • Camila Pimentel
  • Marcia Pinto
  • Sandra Valongueiro
  • Heidi Larson
  • Health Policy Plan.2020 Jul;czaa042. doi: 10.1093/heapol/czaa042.Epub 2020-07-18.

ミエリンオリゴデンドロサイト糖鎖抗体関連視神経炎の臨床的特徴の白人とアジア系人種間での違い

Differences in Clinical Features of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Optic Neuritis in White and Asian Race.
  • Tanyatuth Padungkiatsagul
  • John J Chen
  • Panitha Jindahra
  • Tetsuya Akaishi
  • Toshiyuki Takahashi
  • Ichiro Nakashima
  • Takayuki Takeshita
  • Heather E Moss
  • Am. J. Ophthalmol..2020 Jul;S0002-9394(20)30359-7. doi: 10.1016/j.ajo.2020.07.008.Epub 2020-07-15.

PARP酵素のターゲットエンゲージメントを研究するためのインビトロおよび細胞プローブ

In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement.
  • Tim J Wigle
  • Danielle J Blackwell
  • Laurie B Schenkel
  • Yue Ren
  • W David Church
  • Hetvi J Desai
  • Kerren K Swinger
  • Andrew G Santospago
  • Christina R Majer
  • Alvin Z Lu
  • Mario Niepel
  • Nicholas R Perl
  • Melissa M Vasbinder
  • Heike Keilhack
  • Kevin W Kuntz
  • Cell Chem Biol.2020 Jul;27(7):877-887.e14. S2451-9456(20)30232-4. doi: 10.1016/j.chembiol.2020.06.009.

転移性去勢抵抗性前立腺がんの男性における双極性アンドロゲン療法の多施設共同オープンラベル第II相試験（RESTORE）。アビラテロン投与後とエンザルツアミド投与後のコホートの比較

A Multicohort Open-label Phase II Trial of Bipolar Androgen Therapy in Men with Metastatic Castration-resistant Prostate Cancer (RESTORE): A Comparison of Post-abiraterone Versus Post-enzalutamide Cohorts.
  • Mark C Markowski
  • Hao Wang
  • Rana Sullivan
  • Irina Rifkind
  • Victoria Sinibaldi
  • Michael T Schweizer
  • Benjamin A Teply
  • Nduku Ngomba
  • Wei Fu
  • Michael A Carducci
  • Channing J Paller
  • Catherine H Marshall
  • Mario A Eisenberger
  • Jun Luo
  • Emmanuel S Antonarakis
  • Samuel R Denmeade
  • Eur. Urol..2020 Jul;S0302-2838(20)30471-1. doi: 10.1016/j.eururo.2020.06.042.Epub 2020-07-02.

COVID-19感染症における止血プロファイル

Hemostasis profile in COVID-19 infection.
  • Fernando Barroso Duarte
  • Rosângela Pinheiro Gonçalves Machado
  • Romélia Pinheiro Gonçalves Lemes
  • Isabella Araújo Duarte
  • Beatrice Araújo Duarte
  • Clarissa Maria Gonçalves Machado
  • João Vitor Araújo Duarte
  • Samuel Gonçalves Machado da Rocha
  • Anna Thawanny Gadelha Moura
  • Rosangela de Albuquerque Ribeiro Rodrigues Holanda
  • Rev Assoc Med Bras (1992).2020 05;66(5):571-572. S0104-42302020000500571. doi: 10.1590/1806-9282.66.5.571.Epub 2020-07-03.

ベトナムの気候変動と健康の脆弱性と適応評価、2018年

Vietnam Climate Change and Health Vulnerability and Adaptation Assessment, 2018.
  • Tran Thi Tuyet Hanh
  • Le Thi Thanh Huong
  • Nguyen Thi Lien Huong
  • Tran Nu Quy Linh
  • Nguyen Huu Quyen
  • Nguyen Thi Trang Nhung
  • Kristie Ebi
  • Nguyen Dinh Cuong
  • Ha Van Nhu
  • Tran Mai Kien
  • Simon Hales
  • Do Manh Cuong
  • Nguyen Thi Thi Tho
  • Luu Quoc Toan
  • Nguyen Ngoc Bich
  • Hoang Van Minh
  • Environ Health Insights.2020;14:1178630220924658. 10.1177_1178630220924658. doi: 10.1177/1178630220924658.Epub 2020-06-22.

水でろ過した赤外線Aおよび可視光（wIRA/VIS）治療は、包接結膜炎のモルモットモデルにおけるクラミジア・キャビア誘発性眼炎症および感染負荷を減少させる

Water-filtered Infrared A and visible light (wIRA/VIS) treatment reduces Chlamydia caviae-induced ocular inflammation and infectious load in a Guinea pig model of inclusion conjunctivitis.
  • Aleksandra Inic-Kanada
  • Marijana Stojanovic
  • Radmila Miljkovic
  • Elisabeth Stein
  • Ana Filipovic
  • Antonia Frohns
  • Nadja Zöller
  • Jasmin Kuratli
  • Talin Barisani-Asenbauer
  • Nicole Borel
  • J. Photochem. Photobiol. B, Biol..2020 Jul;209:111953. S1011-1344(20)30403-6. doi: 10.1016/j.jphotobiol.2020.111953.Epub 2020-07-05.

東南アジアの低中所得国の動物病院が直面するバイオセーフティとバイオセキュリティの課題。タイの事例研究

Biosafety and Biosecurity Challenges Facing Veterinary Diagnostic Laboratories in Lower-Middle Income Countries in Southeast Asia: A Case Study of Thailand.
  • Jarunee Siengsanan-Lamont
  • Somjai Kamolsiripichaiporn
  • Soiratchaneekorn Ruanchaimun
  • Tuangthong Patchimasiri
  • Banjong Jongrakwattana
  • Stuart D Blacksell
  • Appl Biosaf.2019 Dec;24(4):220-230. 10.1177_1535676019869771. doi: 10.1177/1535676019869771.Epub 2019-08-19.

リポ多糖類誘発性急性肺障害は、マウスモデルにおける微小管形成センター（RanBPM）分子発現とミトコンドリア介在性アポトーシスシグナル伝達経路のRan-Binding Proteinの増加と関連している

Lipopolysaccharide-Induced Acute Lung Injury Is Associated with Increased Ran-Binding Protein in Microtubule-Organizing Center (RanBPM) Molecule Expression and Mitochondria-Mediated Apoptosis Signaling Pathway in a Mouse Model.
  • Xiaojing Lv
  • Xiaomin Lu
  • Jiping Zhu
  • Qian Wang
  • Med. Sci. Monit..2020 Jul;26:e923172. 923172. doi: 10.12659/MSM.923172.Epub 2020-07-18.

リツキシマブによる維持療法中に多発性血管炎を伴う肉芽腫症とインフルエンザ肺炎を併発した症例で、偽陰性検査を繰り返した結果、COVID-19の診断が遅れた

Repeated false-negative tests delayed diagnosis of COVID-19 in a case with granulomatosis with polyangiitis under maintenance therapy with rituximab and concomitant influenza pneumonia.
  • Samy Hakroush
  • Jonas Franz
  • Jörg Larsen
  • Peter Korsten
  • Martin Sebastian Winkler
  • Björn Tampe
  • Ann. Rheum. Dis..2020 Jul;annrheumdis-2020-218491. doi: 10.1136/annrheumdis-2020-218491.Epub 2020-07-15.

α2Aアドレナリン受容体欠損症は、急性呼吸窮迫症候群におけるノルエピネフリンレベルの上昇と肺胞マクロファージ活性化の阻害により、リポ多糖類誘発性肺障害を減衰させる

Alpha2A-adrenoceptor deficiency attenuates lipopolysaccharide-induced lung injury by increasing norepinephrine levels and inhibiting alveolar macrophage activation in acute respiratory distress syndrome.
  • Zhukai Cong
  • Dan Li
  • Xiangpeng Lv
  • Cui Yang
  • Qiang Zhang
  • Changyi Wu
  • Zongyu Wang
  • Xi Zhu
  • Clin. Sci..2020 Jul;CS20200586. doi: 10.1042/CS20200586.Epub 2020-07-09.

死細胞のファゴサイトーシスの障害によって引き起こされる組織損傷。肺炎におけるγδT細胞の病因に関与するこれまでにない副作用

Tissue Damage Caused by Impaired Phagocytosis of Dead Cells: A Previously Unrecognized Adverse Effect Contributing to the Pathogenesis of γδ T Cells in Pneumonia.
  • Chiaki Kajiwara
  • Soichiro Kimura
  • Yuriko Tanaka
  • Yoshikiyo Akasaka
  • Yoshikazu Ishii
  • Kazuhiro Tateda
  • Immunohorizons.2020 Jul;4(7):402-414. 4/7/402. doi: 10.4049/immunohorizons.2000054.Epub 2020-07-14.

鉄の鎖のUBC-HCT：アル・マルキらによる「鉄の過負荷はDelayed EngraftmentとAssociated with Delayed Engraftment and Increased Non-Relapse Mortality in Recipients of Umbilical Cord Blood Hematopoietic Cell Transplantation」へのコメント 2020

Chains of Iron in UBC-HCT: Comment on "Iron Overload is Associated with Delayed Engraftment and Increased Non-Relapse Mortality in Recipients of Umbilical Cord Blood Hematopoietic Cell Transplantation" by Al Malki et al. 2020.
  • Mary Ann Knovich
  • Biol. Blood Marrow Transplant..2020 Jul;S1083-8791(20)30441-9. doi: 10.1016/j.bbmt.2020.07.012.Epub 2020-07-15.