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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

球状曲線を有するブタのアテロコラーゲンビトリゲル膜と移植可能な人工角膜内皮移植片の開発と評価

Development and evaluation of porcine atelocollagen vitrigel membrane with a spherical curve and transplantable artificial corneal endothelial grafts.
  • Junko Yoshida
  • Ayumi Oshikata-Miyazaki
  • Seiichi Yokoo
  • Satoru Yamagami
  • Toshiaki Takezawa
  • Shiro Amano
  • Invest. Ophthalmol. Vis. Sci..2014 Jul;55(8):4975-81. iovs.14-14211. doi: 10.1167/iovs.14-14211.Epub 2014-07-15.

亜熱帯の3都市における原因別精神障害に対する温度の影響。中国におけるケースクロスオーバー研究

The effect of temperature on cause-specific mental disorders in three subtropical cities: A case-crossover study in China.
  • Shiyu Zhang
  • Yin Yang
  • XinHui Xie
  • Huan Li
  • Rong Han
  • Jiesheng Hou
  • Jia Sun
  • Zhengmin Min Qian
  • Shaowei Wu
  • Cunrui Huang
  • Steven W Howard
  • Fei Tian
  • WenFeng Deng
  • Hualiang Lin
  • Environ Int.2020 Jul;143:105938. S0160-4120(20)31893-6. doi: 10.1016/j.envint.2020.105938.Epub 2020-07-17.

微小腺腺腺症に生じた唾液腺型乳腺癌。症例報告および臨床病理学的レビュー

Salivary gland-type mammary carcinoma arising in microglandular adenosis: A case report and clinicopathological review of the literature.
  • Victoria Rico
  • Yukiko Shibahara
  • Marjorie Monteiro
  • Elzbieta Slodkowska
  • Samantha Tam
  • Pearl Zaki
  • Carlo De Angelis
  • Edward Chow
  • Katarzyna Joanna Jerzak
  • Cancer Treat Res Commun.2020 May;24:100178. S2468-2942(20)30015-0. doi: 10.1016/j.ctarc.2020.100178.Epub 2020-05-12.

Platon: タンパク質配列ベースのレプリコン分布スコアを利用した短読ドラフトアセンブリにおける細菌プラスミドコンティグの同定と特性評価

Platon: identification and characterization of bacterial plasmid contigs in short-read draft assemblies exploiting protein sequence-based replicon distribution scores.
  • Oliver Schwengers
  • Patrick Barth
  • Linda Falgenhauer
  • Torsten Hain
  • Trinad Chakraborty
  • Alexander Goesmann
  • Microb Genom.2020 Jun;doi: 10.1099/mgen.0.000398.Epub 2020-06-24.

ウイルス性糖タンパク質遺伝子のコドン最適化に基づいてラッサ熱ライブ減衰ワクチン

A Lassa Fever Live-Attenuated Vaccine Based on Codon Deoptimization of the Viral Glycoprotein Gene.
  • Yingyun Cai
  • Chengjin Ye
  • Benson Cheng
  • Aitor Nogales
  • Masaharu Iwasaki
  • Shuiqing Yu
  • Kurt Cooper
  • David X Liu
  • Randy Hart
  • Ricky Adams
  • Tyler Brady
  • Elena N Postnikova
  • Jonathan Kurtz
  • Marisa St Claire
  • Jens H Kuhn
  • Juan Carlos de la Torre
  • Luis Martínez-Sobrido
  • mBio.2020 02;11(1). e00039-20. doi: 10.1128/mBio.00039-20.Epub 2020-02-25.

医師が常駐する地上救急医療はSTEMI患者のドアからバルーンまでの時間を有意に短縮しない:日本の単一救急センターにおける観察的研究

A physician-staffed ground emergency medical service does not significantly shorten door-to-balloon time in patients with STEMI: an observational study in a single emergency center in Japan.
  • Yuki Yoshioka
  • Ryota Teshima
  • Mina Gamo
  • Ryuhei Yoneda
  • Naoki Matsunaga
  • Tadaaki Takada
  • Yasushi Fukuta
  • Koichi Kishi
  • Acute Med Surg.2020 Jan-Dec;7(1):e542. AMS2542. doi: 10.1002/ams2.542.Epub 2020-07-15.

遺伝間領域の再配列に基づくラッサウイルス生ワクチン候補の開発

A Lassa Virus Live-Attenuated Vaccine Candidate Based on Rearrangement of the Intergenic Region.
  • Yingyun Cai
  • Masaharu Iwasaki
  • Daisuke Motooka
  • David X Liu
  • Shuiqing Yu
  • Kurt Cooper
  • Randy Hart
  • Ricky Adams
  • Tracey Burdette
  • Elena N Postnikova
  • Jonathan Kurtz
  • Marisa St Claire
  • Chengjin Ye
  • Jens H Kuhn
  • Luis Martínez-Sobrido
  • Juan Carlos de la Torre
  • mBio.2020 03;11(2). e00186-20. doi: 10.1128/mBio.00186-20.Epub 2020-03-24.

グルコース-6-リン酸デヒドロゲナーゼは、Ca1.2と相互作用してCa電流を増加させ、L型カルシウムチャネルの内在性不活性化を減少させる

Glucose-6-phosphate dehydrogenase increases Ca currents by interacting with Ca1.2 and reducing intrinsic inactivation of the L-type calcium channel.
  • Rakhee Gupte
  • Vidhi Dhagia
  • Petra Rocic
  • Rikuo Ochi
  • Sachin A Gupte
  • Am. J. Physiol. Heart Circ. Physiol..2020 Jul;319(1):H144-H158. doi: 10.1152/ajpheart.00727.2019.Epub 2020-05-22.

セファレキシンの皮膚バイオアベイラビリティと抗菌活性を向上させるための熱感応性・生体接着性ナノトランスファーゾームハイドロゲルハイブリッドシステムの開発のための望ましさ機能アプローチ

Desirability function approach for development of a thermosensitive and bioadhesive nanotransfersome-hydrogel hybrid system for enhanced skin bioavailability and antibacterial activity of cephalexin.
  • Sara Salatin
  • Mitra Jelvehgari
  • Drug Dev Ind Pharm.2020 Jul;:1-16. doi: 10.1080/03639045.2020.1788068.Epub 2020-07-07.

化学療法中の顆粒球-コロニー刺激因子の使用とCA27.29と循環腫瘍細胞との関連性-SUCCESS A試験の結果

Use of Granulocyte-colony Stimulating Factor During Chemotherapy and Its Association With CA27.29 and Circulating Tumor Cells-Results From the SUCCESS A Trial.
  • Philip Hepp
  • Peter A Fasching
  • Matthias W Beckmann
  • Tanja Fehm
  • Jessica Salmen
  • Carsten Hagenbeck
  • Bernadette Jäger
  • Peter Widschwendter
  • Nikolaus de Gregorio
  • Fabienne Schochter
  • Sven Mahner
  • Nadia Harbeck
  • Tobias Weissenbacher
  • Ayse-Gül Kurt
  • Thomas W P Friedl
  • Wolfgang Janni
  • Brigitte Rack
  • Clin. Breast Cancer.2018 10;18(5):e1103-e1110. S1526-8209(17)30674-2. doi: 10.1016/j.clbc.2018.06.006.Epub 2018-06-18.

工学的に設計されたヒトカテリシジン抗菌ペプチドはエボラウイルス感染を抑制する

Engineered Human Cathelicidin Antimicrobial Peptides Inhibit Ebola Virus Infection.
  • Yangsheng Yu
  • Christopher L Cooper
  • Guangshun Wang
  • M Jane Morwitzer
  • Krishna Kota
  • Julie P Tran
  • Steven B Bradfute
  • Yan Liu
  • Jiayu Shao
  • Amanda K Zhang
  • Lindsey G Luo
  • St Patrick Reid
  • Steven H Hinrichs
  • Kaihong Su
  • iScience.2020 Mar;23(4):100999. S2589-0042(20)30183-8. doi: 10.1016/j.isci.2020.100999.Epub 2020-03-22.

ボロン酸で機能化した親水性表面を持つメソポーラス磁性粒子を用いて、糖プロテオミクスのための糖ペプチドのマルチモーダル濃縮を目指します

Boronic acid-functionalized mesoporous magnetic particles with a hydrophilic surface for the multimodal enrichment of glycopeptides for glycoproteomics.
  • Lujie Yang
  • Quanqing Zhang
  • Yuanyu Huang
  • Ling Lin
  • Hartmut Schlüter
  • Ke Wang
  • Cuiping Zhang
  • Pengyuan Yang
  • Hongxiu Yu
  • Analyst.2020 Jul;doi: 10.1039/d0an00648c.Epub 2020-07-03.

ナノ構造カーボンベース電気化学(バイオ)センサーの水域および水生生物中の新たな医薬品汚染物質のスクリーニングへの応用.A Review

Application of Nanostructured Carbon-Based Electrochemical (Bio)Sensors for Screening of Emerging Pharmaceutical Pollutants in Waters and Aquatic Species: A Review.
  • Álvaro Torrinha
  • Thiago M B F Oliveira
  • Francisco W P Ribeiro
  • Adriana N Correia
  • Pedro Lima-Neto
  • Simone Morais
  • Nanomaterials (Basel).2020 Jun;10(7). E1268. doi: 10.3390/nano10071268.Epub 2020-06-29.

ドイツにおける片頭痛患者の行政的有病率と罹患率,特徴,処方パターン:レトロスペクティブなクレームデータ分析

Administrative prevalence and incidence, characteristics and prescription patterns of patients with migraine in Germany: a retrospective claims data analysis.
  • Tatjana Roessler
  • Juergen Zschocke
  • Anne Roehrig
  • Michael Friedrichs
  • Heiko Friedel
  • Zaza Katsarava
  • J Headache Pain.2020 Jul;21(1):85. 10.1186/s10194-020-01154-x. doi: 10.1186/s10194-020-01154-x.Epub 2020-07-06.

血管内皮受容体チロシンホスファターゼ:EPHB4およびTIE2との接合体および三元複合体に関連する新規基質の同定

Vascular Endothelial Receptor Tyrosine Phosphatase: Identification of Novel Substrates Related to Junctions and a Ternary Complex with EPHB4 and TIE2.
  • Hannes C A Drexler
  • Matthias Vockel
  • Christian Polaschegg
  • Maike Frye
  • Kevin Peters
  • Dietmar Vestweber
  • Mol. Cell Proteomics.2019 10;18(10):2058-2077. RA119.001716. doi: 10.1074/mcp.RA119.001716.Epub 2019-08-19.

Lactobacillus rhamnosus 2016SWU.05.0601は、免疫関連転写因子および腸内細菌叢の発現を調節することにより、オーバルブミンに感作されたマウスにおける免疫バランスを調節する

Lactobacillus rhamnosus 2016SWU.05.0601 regulates immune balance in ovalbumin-sensitized mice by modulating expression of the immune-related transcription factors and gut microbiota.
  • Jiajia Song
  • Yang Li
  • Jian Li
  • Hongwei Wang
  • Yu Zhang
  • Huayi Suo
  • J. Sci. Food Agric..2020 Jun;doi: 10.1002/jsfa.10554.Epub 2020-06-01.

歯科医師が口腔癌や口腔内潜在的悪性病変の早期発見に用いる手がかり:全国歯科診療連携研究ネットワークからの知見

Cues used by dentists in the early detection of oral cancer and oral potentially malignant lesions: findings from the National Dental Practice-Based Research Network.
  • Alexander Ross Kerr
  • Michael E Robinson
  • Cyril Meyerowitz
  • Douglas E Morse
  • Maria L Aguilar
  • Scott L Tomar
  • Lisa Guerrero
  • Dianne Caprio
  • Linda M Kaste
  • Sonia K Makhija
  • Rahma Mungia
  • Linda Rasubala
  • Walter J Psoter
  • Oral Surg Oral Med Oral Pathol Oral Radiol.2020 May;S2212-4403(20)31011-7. doi: 10.1016/j.oooo.2020.05.007.Epub 2020-05-23.

ソヤサポニンIIは、マウスのYB-1リン酸化とNlrp3-inflammasomeプライミングを減少させることにより、急性肝不全を予防します

Soyasaponin II protects against acute liver failure through diminishing YB-1 phosphorylation and Nlrp3-inflammasome priming in mice.
  • Fangzhao Wang
  • Shenhai Gong
  • Teng Wang
  • Lei Li
  • Haihua Luo
  • Junhao Wang
  • Chenyang Huang
  • Hongwei Zhou
  • Guiming Chen
  • Zhanguo Liu
  • Qifan Zhang
  • Yong Jiang
  • Peng Chen
  • Theranostics.2020;10(6):2714-2726. thnov10p2714. doi: 10.7150/thno.40128.Epub 2020-02-03.

Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial(CAVEAT)。修正集中化学療法とベネトグラックス併用の第Ib相用量漸増試験

Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial (CAVEAT): A Phase Ib Dose-Escalation Study of Venetoclax Combined With Modified Intensive Chemotherapy.
  • Chong Chyn Chua
  • Andrew W Roberts
  • John Reynolds
  • Chun Yew Fong
  • Stephen B Ting
  • Jessica M Salmon
  • Sarah MacRaild
  • Adam Ivey
  • Ing Soo Tiong
  • Shaun Fleming
  • Fiona C Brown
  • Sun Loo
  • Ian J Majewski
  • Stefan K Bohlander
  • Andrew H Wei
  • J. Clin. Oncol..2020 Jul;:JCO2000572. doi: 10.1200/JCO.20.00572.Epub 2020-07-20.

YBX1ホモログYPSは、5-メチルシトシンRNAを優先的に認識することで卵巣生殖細胞幹細胞の発生を促進する

YBX1 homolog YPS promotes ovarian germ line stem cell development by preferentially recognizing 5-methylcytosine RNAs.
  • Fan Zou
  • Renjun Tu
  • Bo Duan
  • Zhenlin Yang
  • Zhaohua Ping
  • Xiaoqing Song
  • Shiyuan Chen
  • Andrew Price
  • Hua Li
  • Allison Scott
  • Anoja Perera
  • Sisi Li
  • Ting Xie
  • Proc. Natl. Acad. Sci. U.S.A..2020 02;117(7):3603-3609. 1910862117. doi: 10.1073/pnas.1910862117.Epub 2020-02-03.

ヒト免疫不全ウイルスおよびC型肝炎ウイルスに感染した患者における動脈硬化性心血管系イベント

Atherosclerotic Cardiovascular Events in Patients Infected With Human Immunodeficiency Virus and Hepatitis C Virus.
  • Boun Kim Tan
  • Mathieu Chalouni
  • Dominique Salmon Ceron
  • Alexandre Cinaud
  • Laure Esterle
  • Marc Arthur Loko
  • Christine Katlama
  • Isabelle Poizot-Martin
  • Didier Neau
  • Julie Chas
  • Philippe Morlat
  • Eric Rosenthal
  • Karine Lacombe
  • Alissa Naqvi
  • Karl Barange
  • Olivier Bouchaud
  • Anne Gervais
  • Caroline Lascoux-Combe
  • Daniel Garipuy
  • Laurent Alric
  • Cécile Goujard
  • Patrick Miailhes
  • Hugues Aumaitre
  • Claudine Duvivier
  • Anne Simon
  • Jose-Luis Lopez-Zaragoza
  • David Zucman
  • François Raffi
  • Estibaliz Lazaro
  • David Rey
  • Lionel Piroth
  • François Boué
  • Camille Gilbert
  • Firouzé Bani-Sadr
  • François Dabis
  • Philippe Sogni
  • Linda Wittkop
  • Franck Boccara
  • Clin. Infect. Dis..2020 Jul;ciaa1014. doi: 10.1093/cid/ciaa1014.Epub 2020-07-20.

アペリンは、アペリン受容体、プロテインキナーゼA、細胞外シグナル制御キナーゼ1/2活性化を介して、ヒトトロフォブラストBeWo細胞による胎盤ホルモン分泌を減少させた

Apelin decreased placental hormoine secretion by human trophoblast BeWo cells via apelin receptor, protein kinase A and extracellular signal-regulated kinases 1/2 activation.
  • M Dawid
  • E Mlyczynska
  • P Kurowska
  • M Sierpowski
  • A Rak
  • J. Physiol. Pharmacol..2019 Dec;70(6). doi: 10.26402/jpp.2019.6.08.Epub 2020-02-19.

P21の組換え型は宿主の免疫応答を調節することで感染を制御している

The Recombinant Form of P21 Controls Infection by Modulating Host Immune Response.
  • Flávia Alves Martins
  • Marlus Alves Dos Santos
  • Júlia de Gouveia Santos
  • Aline Alves da Silva
  • Bruna Cristina Borges
  • Mylla Spirandelli da Costa
  • Paula Cristina Brígido Tavares
  • Samuel Cota Teixeira
  • Rebecca Tavares E Silva Brígido
  • Thaise Lara Teixeira
  • Cassiano Costa Rodrigues
  • Nadjania Saraiva de Lira Silva
  • Rayane Cristina de Oliveira
  • Laura Caroline de Faria
  • Marcela Rezende Lemes
  • Renata Graciele Zanon
  • Tatiana Carla Tomiosso
  • Juliana Reis Machado
  • Marcos Vinicius da Silva
  • Carlo José Freire Oliveira
  • Claudio Vieira da Silva
  • Front Immunol.2020;11:1010. doi: 10.3389/fimmu.2020.01010.Epub 2020-06-05.

イリ科植物のファイトケミカル組成とインビトロ生物学的活性.口腔内細菌バイオフィルムの抑制のための新たな生理活性成分の供給源

Phytochemical Composition and In Vitro Biological Activity of spp. (Iridaceae): A New Source of Bioactive Constituents for the Inhibition of Oral Bacterial Biofilms.
  • Lan Hoang
  • František Beneš
  • Marie Fenclová
  • Olga Kronusová
  • Viviana Švarcová
  • Kateřina Řehořová
  • Eva Baldassarre Švecová
  • Miroslav Vosátka
  • Jana Hajšlová
  • Petr Kaštánek
  • Jitka Viktorová
  • Tomáš Ruml
  • Antibiotics (Basel).2020 Jul;9(7). E403. doi: 10.3390/antibiotics9070403.Epub 2020-07-11.

2つの木材腐朽菌Ganoderma applanatumとLaetiporus sulphureusによるNSAIDsの新規コビマス分解。リグニン分解酵素の誘導、等温および速度論的研究

Novel cobiomass degradation of NSAIDs by two wood rot fungi, Ganoderma applanatum and Laetiporus sulphureus: Ligninolytic enzymes induction, isotherm and kinetic studies.
  • Paul Olusegun Bankole
  • Adedotun Adeyinka Adekunle
  • Byong-Hun Jeon
  • Sanjay Prabhu Govindwar
  • Ecotoxicol. Environ. Saf..2020 Jul;203:110997. S0147-6513(20)30836-8. doi: 10.1016/j.ecoenv.2020.110997.Epub 2020-07-16.

Alinity m HIV-1アッセイの性能の多施設臨床比較評価

Multicenter clinical comparative evaluation of Alinity m HIV-1 assay performance.
  • Patrick Braun
  • Allison Glass
  • Leana Maree
  • Maria Krügel
  • Monia Pacenti
  • Francesco Onelia
  • Rory Gunson
  • Emily Goldstein
  • Laura Martínez-García
  • Juan-Carlos Galán
  • Alba Vilas
  • Jodie D'costa
  • Rizmina Sameer
  • Robert Ehret
  • Heribert Knechten
  • Gudrun Naeth
  • Magali Bouvier-Alias
  • Natalia Marlowe
  • Michael J Palm
  • Ajith M Joseph
  • Jens Dhein
  • Birgit Reinhardt
  • Karin Pfeifer
  • Danijela Lucic
  • Martin Obermeier
  • J. Clin. Virol..2020 Jul;129:104530. S1386-6532(20)30272-9. doi: 10.1016/j.jcv.2020.104530.Epub 2020-07-03.

CTGリピート選択的化学スクリーニングにより、微小管阻害剤が有毒CUG RNAレベルの選択的調節因子として同定された

A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels.
  • Kaalak Reddy
  • Jana R Jenquin
  • Ona L McConnell
  • John D Cleary
  • Jared I Richardson
  • Belinda S Pinto
  • Maja C Haerle
  • Elizabeth Delgado
  • Lori Planco
  • Masayuki Nakamori
  • Eric T Wang
  • J Andrew Berglund
  • Proc. Natl. Acad. Sci. U.S.A..2019 10;116(42):20991-21000. 1901893116. doi: 10.1073/pnas.1901893116.Epub 2019-09-30.