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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

ABL1チロシンキナーゼの阻害は、HTLV-1関連筋症/熱帯性痙性パラパレシス患者の末梢血単核細胞におけるHTLV-1プロウイルス負荷を減少させる

Inhibition of ABL1 tyrosine kinase reduces HTLV-1 proviral loads in peripheral blood mononuclear cells from patients with HTLV-1-associated myelopathy/tropical spastic paraparesis.
  • Daisuke Kodama
  • Masakazu Tanaka
  • Toshio Matsuzaki
  • Kimiko Izumo
  • Nobuaki Nakano
  • Eiji Matsuura
  • Mineki Saito
  • Masahiro Nagai
  • Masahisa Horiuchi
  • Atae Utsunomiya
  • Hiroshi Takashima
  • Ryuji Kubota
  • Shuji Izumo
  • PLoS Negl Trop Dis.2020 Jul;14(7):e0008361. PNTD-D-19-01297. doi: 10.1371/journal.pntd.0008361.Epub 2020-07-15.

植物のアルビニズム:クロロフィルの損失をはるかに超えて。野生型とアルビノのロイヤルポインシアナ(Delonix regia)の苗の構造と生理学的側面

Albinism in plants: far beyond the loss of chlorophyll. Structural and physiological aspects of wild-type and albino royal poinciana (Delonix regia) seedlings.
  • Lázara Aline Simões Silva
  • Vitor Fernandes Sampaio
  • Lília Cristina Souza Barbosa
  • Mariana Machado
  • Denisele Neuza Aline Flores-Borges
  • Juliana de Fátima Sales
  • Denis Coelho de Oliveira
  • Juliana Lischka Sampaio Mayer
  • Vinicius Coelho Kuster
  • Diego Ismael Rocha
  • Plant Biol (Stuttg).2020 Jun;doi: 10.1111/plb.13146.Epub 2020-06-16.

gen.nov. sp.nov.は、地衣類の最初のバクテリオクロロフィルを含有し、精神親和性および酸性親和性のバクテリオビオンである

gen. nov., sp. nov., the first bacteriochlorophyll -containing, psychrophilic and acidophilic bacteriobiont of lichen species.
  • Timofey A Pankratov
  • Denis S Grouzdev
  • Ekaterina O Patutina
  • Tatiana V Kolganova
  • Julia J Berestovskaya
  • Aleksandr A Ashikhmin
  • Int. J. Syst. Evol. Microbiol..2020 Jul;doi: 10.1099/ijsem.0.004318.Epub 2020-07-13.

液体マイクロジャンクション表面サンプリング-質量分析法を用いた迅速で包括的なリピドミクス分析のためのTiO2コーティング上のグリセロリン脂質からの糖脂質/スフィンゴ脂質の分離

Separation of Glycolipids/Sphingolipids from Glycerophospholipids on TiO2 Coating in Aprotic Solvent for Rapid Comprehensive Lipidomic Analysis with Liquid Microjunction Surface Sampling-Mass Spectrometry.
  • Zehui Huang
  • Qian Wu
  • Hongmei Lu
  • Yang Wang
  • Zhimin Zhang
  • Anal. Chem..2020 Jul;doi: 10.1021/acs.analchem.0c01870.Epub 2020-07-15.

患者由来の細胞アトラスが神経膠芽腫の精密標的化に役立つ

A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma.
  • Patrik Johansson
  • Cecilia Krona
  • Soumi Kundu
  • Milena Doroszko
  • Sathishkumar Baskaran
  • Linnéa Schmidt
  • Claire Vinel
  • Elin Almstedt
  • Ramy Elgendy
  • Ludmila Elfineh
  • Caroline Gallant
  • Sara Lundsten
  • Fernando J Ferrer Gago
  • Aleksi Hakkarainen
  • Petra Sipilä
  • Maria Häggblad
  • Ulf Martens
  • Bo Lundgren
  • Melanie M Frigault
  • David P Lane
  • Fredrik J Swartling
  • Lene Uhrbom
  • Marika Nestor
  • Silvia Marino
  • Sven Nelander
  • Cell Rep.2020 Jul;32(2):107897. S2211-1247(20)30878-0. doi: 10.1016/j.celrep.2020.107897.

ヒドロキシクロロキンによるCOVID-19から最前線の医療従事者を守るための事前暴露予防法。カナダ、トロントで行われた無作為化プラセボ対照多施設試験のプロトコールの構造化された要約

Protecting Frontline Health Care Workers from COVID-19 with Hydroxychloroquine Pre-exposure Prophylaxis: A structured summary of a study protocol for a randomised placebo-controlled multisite trial in Toronto, Canada.
  • Julie K Wright
  • Darrell H S Tan
  • Sharon L Walmsley
  • Jennifer Hulme
  • Erin O'Connor
  • Carolyn Snider
  • Ivy Cheng
  • Adrienne K Chan
  • Bjug Borgundvaag
  • Shelley McLeod
  • Michael H Gollob
  • Rosemarie J Clarke
  • Linda Dresser
  • Fatima Haji
  • Tony Mazzulli
  • Samira Mubareka
  • Peter Jüni
  • Dominic Lee
  • George Tomlinson
  • Kevin C Kain
  • Megan Landes
  • Trials.2020 Jul;21(1):647. 10.1186/s13063-020-04577-8. doi: 10.1186/s13063-020-04577-8.Epub 2020-07-14.

高脂肪食と抗生物質が協調的にミトコンドリアのバイオエネルギーを損なうことで、炎症性腸疾患の前段階を悪化させているバイオシスを誘発する

High-Fat Diet and Antibiotics Cooperatively Impair Mitochondrial Bioenergetics to Trigger Dysbiosis that Exacerbates Pre-inflammatory Bowel Disease.
  • Jee-Yon Lee
  • Stephanie A Cevallos
  • Mariana X Byndloss
  • Connor R Tiffany
  • Erin E Olsan
  • Brian P Butler
  • Briana M Young
  • Andrew W L Rogers
  • Henry Nguyen
  • Kyongchol Kim
  • Sang-Woon Choi
  • Eunsoo Bae
  • Je Hee Lee
  • Ui-Gi Min
  • Duk-Chul Lee
  • Andreas J Bäumler
  • Cell Host Microbe.2020 Jul;S1931-3128(20)30303-6. doi: 10.1016/j.chom.2020.06.001.Epub 2020-07-09.

トロンボスポンジン-1は、心臓内皮細胞の感染初期段階におけるYes-Associated Proteinの核内転座に重要な役割を果たしている

Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of Infection in Heart Endothelial Cells.
  • Ashutosh Arun
  • Kayla J Rayford
  • Ayorinde Cooley
  • Girish Rachakonda
  • Fernando Villalta
  • Siddharth Pratap
  • Maria F Lima
  • Nader Sheibani
  • Pius N Nde
  • Int J Mol Sci.2020 Jul;21(14). E4912. doi: 10.3390/ijms21144912.Epub 2020-07-12.

腸内マイクロバイオームは、胆汁酸-タイプI-IFNシグナル伝達軸を介してアルファウイルスの感染と伝播を制限する

The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis.
  • Emma S Winkler
  • Swathi Shrihari
  • Barry L Hykes
  • Scott A Handley
  • Prabhakar S Andhey
  • Yan-Jang S Huang
  • Amanda Swain
  • Lindsay Droit
  • Kranthi K Chebrolu
  • Matthias Mack
  • Dana L Vanlandingham
  • Larissa B Thackray
  • Marina Cella
  • Marco Colonna
  • Maxim N Artyomov
  • Thaddeus S Stappenbeck
  • Michael S Diamond
  • Cell.2020 Jul;S0092-8674(20)30806-0. doi: 10.1016/j.cell.2020.06.029.Epub 2020-07-08.

妊娠後期の熱ストレスは、豚モデルでは、変更された子孫の腸内微生物のコロニゼーションと血清代謝物と母体の微生物伝達を混乱させる

Heat stress during late gestation disrupts maternal microbial transmission with altered offspring's gut microbial colonization and serum metabolites in a pig model.
  • Jianwen He
  • Weijiang Zheng
  • Chengyuan Tao
  • Huiduo Guo
  • Yongqiang Xue
  • Ruqian Zhao
  • Wen Yao
  • Environ. Pollut..2020 Jun;266(Pt 3):115111. S0269-7491(20)31749-8. doi: 10.1016/j.envpol.2020.115111.Epub 2020-06-29.

オクラホマ州南東部に生息するツバメHirundo rustica (Aves: Passeriformes: Hirundinidae)からの新種Eimerian (Apicomplexa: Eimeriidae)。新世界のPasseriformesから第4のEimerian種

A New Eimerian (Apicomplexa: Eimeriidae) from the Barn Swallow, Hirundo rustica (Aves: Passeriformes: Hirundinidae), in Southeastern Oklahoma: The Fourth Eimerian Species from New World Passeriformes.
  • Chris T McAllister
  • John A Hnida
  • J. Parasitol..2019 Oct;105(5):693-696. 420579. doi: 10.1645/19-105.

GLUT1およびGLUT4の阻害剤としてのフリルチアゾリジンジオン誘導体の構造設計と合成、およびその抗白血病能の評価

Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential.
  • Kalpana Tilekar
  • Neha Upadhyay
  • Jessica D Hess
  • Lucasantiago Henze Macias
  • Piotr Mrowka
  • Renato J Aguilera
  • Franz-Josef Meyer-Almes
  • Cristina V Iancu
  • Jun-Yong Choe
  • C S Ramaa
  • Eur J Med Chem.2020 Jul;202:112603. S0223-5234(20)30575-4. doi: 10.1016/j.ejmech.2020.112603.Epub 2020-07-02.

マナティーの死亡事故で環境緊急の場となっているビッツァル川の炭化水素汚染水の浄化にはバイオリアクターを利用する

Bioreactors for the remediation of hydrocarbon-polluted water of the Bitzal River, a place of environmental emergency due to the death of manatees.
  • Castañeda-Chávez María Del Refugio
  • Isidoro-Pio Ángel de Jesus
  • Lango-Reynoso Fabiola
  • Lizardi-Jiménez Manuel Alejandro
  • Environ. Pollut..2020 Jul;266(Pt 1):115171. S0269-7491(19)37580-3. doi: 10.1016/j.envpol.2020.115171.Epub 2020-07-07.

このように、PacBio の一分子ロングリードシークエンシングは、Pinctada fucata martensii のトランスクリプトームの複雑さと多様性を解明することができた

PacBio single molecule long-read sequencing provides insight into the complexity and diversity of the Pinctada fucata martensii transcriptome.
  • Hua Zhang
  • Hanzhi Xu
  • Huiru Liu
  • Xiaolan Pan
  • Meng Xu
  • Gege Zhang
  • Maoxian He
  • BMC Genomics.2020 Jul;21(1):481. 10.1186/s12864-020-06894-3. doi: 10.1186/s12864-020-06894-3.Epub 2020-07-13.

癌におけるビンクリスチン抵抗性の克服:ピペリンに着想を得たP-糖タンパク質阻害剤の計算科学的設計と発見

Overcoming vincristine resistance in cancer: computational design and discovery of piperine inspired P-glycoprotein inhibitors.
  • Safiulla Basha Syed
  • Shu-Yu Lin
  • Hemant Arya
  • I-Hsuan Fu
  • Teng-Kuang Yeh
  • Mariasoosai Ramya Chandar Charles
  • Latha Periyasamy
  • Hsing-Pang Hsieh
  • Mohane Selvaraj Coumar
  • Chem Biol Drug Des.2020 Jul;doi: 10.1111/cbdd.13758.Epub 2020-07-07.

母乳中のDHA濃度と母体の食事とサプリメントの使用との関連。日本人ヒト乳調査コホートのデータの横断的分析

Association of DHA Concentration in Human Breast Milk with Maternal Diet and Use of Supplements: A Cross-Sectional Analysis of Data from the Japanese Human Milk Study Cohort.
  • Hiroshi M Ueno
  • Satoshi Higurashi
  • Yuzuka Shimomura
  • Ryota Wakui
  • Hiroaki Matsuura
  • Makoto Shiota
  • Hiroaki Kubouchi
  • Jun-Ichi Yamamura
  • Yasuhiro Toba
  • Toshiya Kobayashi
  • Curr Dev Nutr.2020 Jul;4(7):nzaa105. nzaa105. doi: 10.1093/cdn/nzaa105.Epub 2020-06-15.

Leuconostoc pseudenteroidesは、高脂肪食の肥満マウスにおけるジヒドロセラミドとFirmicutesおよびProteobacteriaの株との相関を改善し、肝代謝のアンバランスを改善します

Leuconostoc pseudomesenteroides improves microbiota dysbiosis and liver metabolism imbalance and ameliorates the correlation between dihydroceramide and strains of Firmicutes and Proteobacteria in high fat diet obese mice.
  • Mengzhen Sun
  • Qiya Wang
  • Maomao Zhang
  • Guohua Zhang
  • Tao Wu
  • Rui Liu
  • Wenjie Sui
  • Jiaojiao Zhang
  • Jinjin Yin
  • Min Zhang
  • Food Funct.2020 Jul;doi: 10.1039/d0fo01009j.Epub 2020-07-15.

小児期のマルトリートメントへの暴露とその後の機能的体性および内臓性疼痛症候群の発症との関連

The association between exposure to childhood maltreatment and the subsequent development of functional somatic and visceral pain syndromes.
  • Joht Singh Chandan
  • Deepiksana Keerthy
  • Dawit Tefra Zemedikun
  • Kelvin Okoth
  • Krishna Margadhamane Gokhale
  • Karim Raza
  • Siddhartha Bandyopadhyay
  • Julie Taylor
  • Krishnarajah Nirantharakumar
  • EClinicalMedicine.2020 Jun;23:100392. S2589-5370(20)30136-X. doi: 10.1016/j.eclinm.2020.100392.Epub 2020-06-06.

脳膿瘍集の内視鏡治療における新たな展望:対象、手技、症例シリーズでの結果、文献の概要

New perspectives in the endoscopic treatment of brain purulent collections: targets, techniques, results in a case series, and overview of the literature.
  • Alessandro Fiorindi
  • Elisabetta Marton
  • Giorgio Gioffrè
  • Antonio Biroli
  • Luca Basaldella
  • Marco Maria Fontanella
  • Pierluigi Longatti
  • Acta Neurochir (Wien).2020 May;10.1007/s00701-020-04301-0. doi: 10.1007/s00701-020-04301-0.Epub 2020-05-02.

前立腺放射線治療のための膀胱と直腸のディープラーニングとアトラスベースの自動輪郭作成の臨床評価

Clinical evaluation of deep learning and atlas based auto-contouring of bladder and rectum for prostate radiotherapy.
  • W Jeffrey Zabel
  • Jessica L Conway
  • Adam Gladwish
  • Julia Skliarenko
  • Giulio Didiodato
  • Leah Goorts-Matthews
  • Adam Michalak
  • Sarah Reistetter
  • Jenna King
  • Keith Nakonechny
  • Kyle Malkoske
  • Muoi N Tran
  • Nevin McVicar
  • Pract Radiat Oncol.2020 Jun;S1879-8500(20)30161-2. doi: 10.1016/j.prro.2020.05.013.Epub 2020-06-26.

飼育・育種により選択されたβ-1, 4-N-アセチルグルコサミニダーゼ1遺伝子は、Bombyx moriの繭構築に関与している

The beta-1, 4-N-acetylglucosaminidase 1 gene, selected by domestication and breeding, is involved in cocoon construction of Bombyx mori.
  • Chunlin Li
  • Xiaoling Tong
  • Weidong Zuo
  • Hai Hu
  • Gao Xiong
  • Minjin Han
  • Rui Gao
  • Yue Luan
  • Kunpeng Lu
  • Tingting Gai
  • Zhonghuai Xiang
  • Cheng Lu
  • Fangyin Dai
  • PLoS Genet..2020 Jul;16(7):e1008907. PGENETICS-D-19-01858. doi: 10.1371/journal.pgen.1008907.Epub 2020-07-15.

ラット血液中のオレキシン-1受容体の遺伝子発現レベルと前頭前野、新規性探索、覚醒剤依存傾向との関連性の評価:バイオマーカー候補

Evaluation of the relationship between the gene expression level of orexin-1 receptor in the rat blood and prefrontal cortex, novelty-seeking, and proneness to methamphetamine dependence: a candidate biomarker.
  • Mahnoosh Tavakkolifard
  • Nasim Vousooghi
  • Sara Mahboubi
  • Fereshteh Golab
  • Shahram Ejtemaei Mehr
  • Mohammad Reza Zarrindast
  • Peptides.2020 Jul;:170368. S0196-9781(20)30117-0. doi: 10.1016/j.peptides.2020.170368.Epub 2020-07-12.