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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

ペルーのピウラで先天性一般化リポジストロフィーの高い有病率

High prevalence of congenital generalized lipodystrophy in Piura, Peru.
  • Nelson David Purizaca-Rosillo
  • Yamalí Elena Benites-Cóndor
  • Hugo Abarca Barriga
  • Carlos Del Águila Villar
  • Miguel Chávez Pastor
  • Littner Franco Palacios
  • Ricardo Olea Zapata
  • James Rejas Parodi
  • Luz Martinez Uceda
  • Felix Chavesta Velásquez
  • John Gamarra Vilela
  • Sebastián Arámbulo Castillo
  • Amanda Ávila Reyes
  • Intractable Rare Dis Res.2020 Feb;9(1):58-60. doi: 10.5582/irdr.2020.01004.

思春期早発症の診断:思春期早発症の診断と治療のための臨床ガイドライン

Diagnosis of precocious puberty: clinical guideline for the diagnosis and treatment of precocious puberty.
  • América L Miranda-Lora
  • Margarita Torres-Tamayo
  • Jessie N Zurita-Cruz
  • Blanca E Aguilar-Herrera
  • Raúl Calzada-León
  • Aleida J Rivera-Hernández
  • Marco A Morales-Pérez
  • Miriam M Padrón-Martínez
  • María L Ruiz-Reyes
  • Leticia M García-Morales
  • Consuelo Barrón-Uribe
  • Sletza L Arguinzoniz-Valenzuela
  • Mayra C Torres-Castañeda
  • Lorena Lizárraga-Paulin
  • Jorge A Núñez-Hernández
  • Judith Cornejo-Barrera
  • María T Vidal-González
  • María R Martínez-Alvarado
  • Elisa Nishimura-Meguro
  • Luz E Bravo-Ríos
  • Eulalia P Garrido-Magaña
  • José A Orozco-Morales
  • Patricia G Medina-Bravo
  • Ninel Coyote-Estrada
  • M Fernanda Castilla-Peón
  • Bol Med Hosp Infant Mex.2020;77(Supl 1):7-14. j77/Supl 1/7. doi: 10.24875/BMHIM.20000075.

インディアンラッセル毒由来の神経成長因子(RVV-NGFa)は、乳がん細胞に発現するTrkA受容体に高親和性で結合している。蛍光標識RVVV-NGFaの乳がん臨床診断への応用

Nerve growth factor from Indian Russell's viper venom (RVV-NGFa) shows high affinity binding to TrkA receptor expressed in breast cancer cells: Application of fluorescence labeled RVV-NGFa in the clinical diagnosis of breast cancer.
  • Taufikul Islam
  • Munmi Majumder
  • Anil Bidkar
  • Siddhartha S Ghosh
  • Rupak Mukhopadhyay
  • Yuri Utkin
  • Ashis K Mukherjee
  • Biochimie.2020 Jun;176:31-44. S0300-9084(20)30136-X. doi: 10.1016/j.biochi.2020.06.004.Epub 2020-06-23.

カドミウム誘発性生殖毒性ラットの精子指標、アクロソーム反応、精子DNA完全性に及ぼすカルポロビア・リュテアのメタノール根抽出物の影響について検討した

Effects of the methanol root extract of Carpolobia lutea on sperm indices, acrosome reaction, and sperm DNA integrity in cadmium-induced reproductive toxicity in male Wistar rats.
  • Adeniran Oluwadamilare Akinola
  • Adekunle Wahab Oyeyemi
  • Oluyemi O Daramola
  • Yinusa Raji
  • JBRA Assist Reprod.2020 Jun;doi: 10.5935/1518-0557.20200036.Epub 2020-06-08.

カベオリン-1アブレーションは、実験緑内障における網膜内損傷に対する部分的な保護とアポトーシス活性化を減少させる

Caveolin-1 Ablation Imparts Partial Protection Against Inner Retinal Injury in Experimental Glaucoma and Reduces Apoptotic Activation.
  • Mojdeh Abbasi
  • Vivek K Gupta
  • Nitin Chitranshi
  • Veer B Gupta
  • Mehdi Mirzaei
  • Yogita Dheer
  • Linda Garthwaite
  • Thiri Zaw
  • Robert G Parton
  • Yuyi You
  • Stuart L Graham
  • Mol. Neurobiol..2020 Jun;10.1007/s12035-020-01948-9. doi: 10.1007/s12035-020-01948-9.Epub 2020-06-23.

拡大された分子系統と形態学的解析から、シダ科デンシュタットリア属の進化に新たな知見が得られた

New insights into the evolution of the fern family Dennstaedtiaceae from an expanded molecular phylogeny and morphological analysis.
  • Pedro B Schwartsburd
  • Leon R Perrie
  • Patrick Brownsey
  • Lara D Shepherd
  • Hui Shang
  • David S Barrington
  • Michael A Sundue
  • Mol. Phylogenet. Evol..2020 Jun;150:106881. S1055-7903(20)30153-6. doi: 10.1016/j.ympev.2020.106881.Epub 2020-06-06.

急性視神経炎(MOVING)の最初の片側エピソードの後の Fingolimod - 無作為化、評価者盲検、活性化対照、第2相試験の予備的な結果

Fingolimod after a first unilateral episode of acute optic neuritis (MOVING) - preliminary results from a randomized, rater-blind, active-controlled, phase 2 trial.
  • Christian Albert
  • Janine Mikolajczak
  • Anja Liekfeld
  • Sophie K Piper
  • Michael Scheel
  • Hanna G Zimmermann
  • Claus Nowak
  • Jan Dörr
  • Judith Bellmann-Strobl
  • Claudia Chien
  • Alexander U Brandt
  • Friedemann Paul
  • Olaf Hoffmann
  • BMC Neurol.2020 Mar;20(1):75. 10.1186/s12883-020-01645-z. doi: 10.1186/s12883-020-01645-z.Epub 2020-03-03.

非アレルギー性およびアレルギー性ドナーのヒト初代鼻上皮細胞の物理的および免疫学的バリアー

Physical and immunological barrier of human primary nasal epithelial cells from non-allergic and allergic donors.
  • Carolin Bergougnan
  • Daniela C Dittlein
  • Elke Hümmer
  • Rosalie Riepl
  • Selina Eisenbart
  • Dominik Böck
  • Lena Griesbaum
  • Anna Weigl
  • Athanasios Damialis
  • Alexander Hartwig
  • Avidan U Neumann
  • Johannes Zenk
  • Claudia Traidl-Hoffmann
  • Stefanie Gilles
  • World Allergy Organ J.2020 Mar;13(3):100109. S1939-4551(20)30012-0. doi: 10.1016/j.waojou.2020.100109.Epub 2020-03-09.

活性化プロトロンビン複合体濃縮物は、抗凝固剤関連出血または緊急手術前の直接経口投与のためのものです。止血および血栓症の転帰

Activated prothrombin complex concentrates for direct oral anticoagulant-associated bleeding or urgent surgery: Hemostatic and thrombotic outcomes.
  • Joseph R Shaw
  • Marc Carrier
  • Dar Dowlatshahi
  • Santanu Chakraborty
  • Melanie Tokessy
  • Hakan Buyukdere
  • Lana A Castellucci
  • Thromb. Res..2020 Jul;195:21-28. S0049-3848(20)30286-3. doi: 10.1016/j.thromres.2020.06.044.Epub 2020-07-01.

子宮頸部扁平上皮癌および腺癌に対する確定的同時化学放射線療法の全生存、局所領域再発、遠隔転移:コホート研究の傾向スコアマッチング解析の前後

Overall survival, locoregional recurrence, and distant metastasis of definitive concurrent chemoradiotherapy for cervical squamous cell carcinoma and adenocarcinoma: before and after propensity score matching analysis of a cohort study.
  • Jiaqiang Zhang
  • Lei Qin
  • Ho-Min Chen
  • Han-Chuan Hsu
  • Chih-Chi Chuang
  • Dar Chen
  • Szu-Yuan Wu
  • Am J Cancer Res.2020;10(6):1808-1820. Epub 2020-06-01.

免疫浸潤の指標を組み合わせることで、高悪性度漿液性卵巣癌の生存予測に相加的な効果を示した

Combining measures of immune infiltration shows additive effect on survival prediction in high-grade serous ovarian carcinoma.
  • Anne Montfort
  • Stephanie Owen
  • Anna M Piskorz
  • Anna Supernat
  • Luiza Moore
  • Sarwah Al-Khalidi
  • Steffen Böhm
  • Paul Pharoah
  • Jacqueline McDermott
  • Frances R Balkwill
  • James D Brenton
  • Br. J. Cancer.2020 Jun;122(12):1803-1810. 10.1038/s41416-020-0822-x. doi: 10.1038/s41416-020-0822-x.Epub 2020-04-06.

シスプラチン誘導性miR-425-3pのExosomal Transferは、オートファジーの活性化を介してNSCLCにおけるシスプラチン抵抗性をもたらす

Exosomal Transfer Of Cisplatin-Induced miR-425-3p Confers Cisplatin Resistance In NSCLC Through Activating Autophagy.
  • Yuzhu Ma
  • Daolu Yuwen
  • Jingwei Chen
  • Bingfeng Zheng
  • Jian Gao
  • Minmin Fan
  • Wenwen Xue
  • Yixuan Wang
  • Wuhao Li
  • Yongqian Shu
  • Qiang Xu
  • Yan Shen
  • Int J Nanomedicine.2019;14:8121-8132. 221383. doi: 10.2147/IJN.S221383.Epub 2019-10-07.

ラパコールおよびノルラパコール誘導体の抗菌活性および調節活性のインシリコ評価

In silico evaluation of the antibacterial and modulatory activity of lapachol and nor-lapachol derivates.
  • Fernando Gomes Figueredo
  • Ingrid T L Ramos
  • Josinete A Paz
  • Tania M S Silva
  • Celso A Camara
  • Cícera Datiane de Morais Oliveira-Tintino
  • Saulo Relison Tintino
  • Pablo Antônio Maia de Farias
  • Henrique Douglas Melo Coutinho
  • Marta Maria de F Fonteles
  • Microb. Pathog..2020 Jul;144:104181. S0882-4010(20)30468-X. doi: 10.1016/j.micpath.2020.104181.Epub 2020-04-08.

注意欠陥/多動性障害児におけるメチルフェニデートと血清成長マーカーとの関連性の予備的調査。横断的ケースコントロール研究

Preliminary Investigation of Association between Methylphenidate and Serum Growth Markers in Children with Attention-Deficit/Hyperactivity Disorder: A Cross-Sectional Case-Control Study.
  • Woo Jin Kim
  • Young Rong Bang
  • Je-Wook Kang
  • Jae Ho Yoo
  • Seong Hwan Kim
  • Jae Hong Park
  • Soa Chongsonyon Chongsin Uihak.2020 Jul;31(3):154-160. JKACAP-31-154. doi: 10.5765/jkacap.200014.

変換療法に関する独立法医学専門家グループの声明

Statement of the Independent Forensic Expert Group on Conversion Therapy.
  • Djordje Alempijevic
  • Rusudan Beriashvili
  • Jonathan Beynon
  • Djordje Alempijevic Petersen
  • Bettina Birmanns
  • Marie Brasholt
  • Juliet Cohen
  • Djordje Alempijevic Petersen
  • Maximo Duque
  • Pierre Duterte
  • Adriaan Van Es
  • Ravindra Fernando
  • Sebnem Korur Fincanci
  • Steen Holger Hansen
  • Sana Hamzeh
  • Lilla Hardi
  • Michele Heisler
  • Vincent Iacopino
  • Peter Mygind Leth
  • James Lin
  • Said Louahlia
  • Hege Luytkis
  • Said Louahlia
  • Maria-Dolores Morcillo-Mendez
  • Alejandro Moreno
  • Valeria Moscoso
  • Resmiye Oral
  • Onder Ozkalipci
  • Jason Payne-James
  • Jose Quiroga
  • Onder Ozkalipci
  • Hernan Reyes
  • Sidsel Rogde
  • Antti Sajantilla
  • Onder Ozkalipci
  • Matthis Schick
  • Agis Terzidis
  • Jorgen Lange Thomsen
  • Morris Tidball-Binz
  • Felicitas Treue
  • Peter Vanezis
  • Duarte Nuno Viera
  • Torture.2020;30(1):66-78. doi: 10.7146/torture.v30i1.119654.

クルクミンとメトホルミンの組み合わせは、LNCaP前立腺癌細胞株において、細胞周期に影響を与えずに細胞増殖を抑制し、アポトーシスを誘導する

Combination of Curcumin and Metformin Inhibits Cell Growth and Induces Apoptosis without Affecting the Cell Cycle in LNCaP Prostate Cancer Cell Line.
  • Seyed Sadegh Eslami
  • Davod Jafari
  • Hamed Montazeri
  • Majid Sadeghizadeh
  • Parastoo Tarighi
  • Nutr Cancer.2020 Jul;:1-14. doi: 10.1080/01635581.2020.1783327.Epub 2020-07-13.

同種幹細胞移植後 11 日目から 20 日目までのシロリムス濃度が肝副鼻腔閉塞症候群のリスクに及ぼす影響

Effect of Sirolimus levels between days 11 and 20 after allogeneic stem cell transplantation on the risk of hepatic sinusoidal obstruction syndrome.
  • Vaibhav Agrawal
  • Praveen Ranganath
  • Kirsten D Ervin
  • Caitlin A Schmidt
  • Elizabeth A Cox
  • Robert P Nelson
  • Jennifer E Schwartz
  • Mohammad Abu Zaid
  • Rafat Abonour
  • Michael J Robertson
  • Bryan J Brinda
  • Shawn P Griffin
  • Teresa C Thakrar
  • Sherif S Farag
  • Bone Marrow Transplant..2020 Jul;10.1038/s41409-020-0987-1. doi: 10.1038/s41409-020-0987-1.Epub 2020-07-04.

米国メイン州とニュージャージー州の私有井戸世帯における飲料水のヒ素曝露量とヒ素処理による健康リスクの減少

Reduction in drinking water arsenic exposure and health risk through arsenic treatment among private well households in Maine and New Jersey, USA.
  • Qiang Yang
  • Sara V Flanagan
  • Steven Chillrud
  • James Ross
  • Wenke Zeng
  • Charles Culbertson
  • Steven Spayd
  • Lorraine Backer
  • Andrew E Smith
  • Yan Zheng
  • Sci. Total Environ..2020 May;738:139683. S0048-9697(20)33203-4. doi: 10.1016/j.scitotenv.2020.139683.Epub 2020-05-25.

エタノール、Δ(9)-テトラヒドロカンナビノール(THC)、およびそれらの組み合わせの空間記憶および認知柔軟性に対する破壊的効果

Deleterious Effects of Ethanol, Δ(9)-Tetrahydrocannabinol (THC), and Their Combination on the Spatial Memory and Cognitive Flexibility in Adolescent and Adult Male Rats in the Barnes Maze Task.
  • Ewa Gibula-Tarlowska
  • Karolina Wydra
  • Jolanta H Kotlinska
  • Pharmaceutics.2020 Jul;12(7). E654. doi: 10.3390/pharmaceutics12070654.Epub 2020-07-09.

妊娠中のサイトメガロウイルス感染症に対処するためには、血清学的検査よりも衛生管理の促進の方が良いかもしれない:方法論的評価と意思決定の分析

Hygiene promotion might be better than serological screening to deal with Cytomegalovirus infection during pregnancy: a methodological appraisal and decision analysis.
  • Agathe Billette de Villemeur
  • Pierre Tattevin
  • Louis-Rachid Salmi
  • BMC Infect. Dis..2020 Jun;20(1):418. 10.1186/s12879-020-05139-8. doi: 10.1186/s12879-020-05139-8.Epub 2020-06-16.

炎症性腸疾患における5-アミノサリチル酸の使用に関する大腸炎・クローン財団(インド)のコンセンサス声明

Colitis and Crohn's Foundation (India) consensus statements on use of 5-aminosalicylic acid in inflammatory bowel disease.
  • Ajit Sood
  • Vineet Ahuja
  • Vandana Midha
  • Saroj Kant Sinha
  • C Ganesh Pai
  • Saurabh Kedia
  • Varun Mehta
  • Sawan Bopanna
  • Philip Abraham
  • Rupa Banerjee
  • Shobna Bhatia
  • Karmabir Chakravartty
  • Sunil Dadhich
  • Devendra Desai
  • Manisha Dwivedi
  • Bhabhadev Goswami
  • Kirandeep Kaur
  • Rajeev Khosla
  • Ajay Kumar
  • Ramit Mahajan
  • S P Misra
  • Kiran Peddi
  • Shivaram Prasad Singh
  • Arshdeep Singh
  • Intest Res.2020 Jul;ir.2019.09176. doi: 10.5217/ir.2019.09176.Epub 2020-07-13.

TPC1 欠損または遮断は、全身性アナフィラキシーおよび肥満細胞活性を増強する

TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity.
  • Elisabeth Arlt
  • Marco Fraticelli
  • Volodymyr Tsvilovskyy
  • Wiebke Nadolni
  • Andreas Breit
  • Thomas J O'Neill
  • Stefanie Resenberger
  • Gunther Wennemuth
  • Christian Wahl-Schott
  • Martin Biel
  • Christian Grimm
  • Marc Freichel
  • Thomas Gudermann
  • Norbert Klugbauer
  • Ingrid Boekhoff
  • Susanna Zierler
  • Proc. Natl. Acad. Sci. U.S.A..2020 Jul;201920122. doi: 10.1073/pnas.1920122117.Epub 2020-07-13.

職業的にヒ素、カドミウムおよび鉛に曝露された人のCNR1、MC4R、LEP、FTOおよびVDR遺伝子多型といくつかの基本的な毒物学的パラメータとの関係

The Relationship Between Selected CNR1, MC4R, LEP, FTO and VDR Gene Polymorphisms and Several Basic Toxicological Parameters Among Persons Occupationally Exposed to Arsenic, Cadmium and Lead.
  • Tomasz Matys
  • Anna Szymańska-Chabowska
  • Katarzyna Bogunia-Kubik
  • Beata Smyk
  • Małgorzata Kamińska
  • Grzegorz Mazur
  • Rafał Poręba
  • Paweł Gać
  • J Clin Med.2020 Apr;9(4). E1040. doi: 10.3390/jcm9041040.Epub 2020-04-07.

Klippel-Trénaunay症候群患者における血栓塞栓性イベントの危険因子としての異常な静脈解剖学:コホート研究の中のケースコントロール研究

Aberrant venous anatomy as a risk factor for thromboembolic events in patients with Klippel-Trénaunay Syndrome: case-control study within a cohort study.
  • Lilly Geertruida Johanna Maria Zwerink
  • D Maroeska Wm Te Loo
  • Richard Praster
  • Bas H Verhoeven
  • Carine Jm van der Vleuten
  • J. Am. Acad. Dermatol..2020 Jul;S0190-9622(20)32183-6. doi: 10.1016/j.jaad.2020.07.019.Epub 2020-07-15.

ネオババイソフラボンは、RANKL シグナルを介した TRAF6 と c-Src のリクルート、NF-κB、MAPK、Akt パスウェイを阻害することにより、破骨細胞の発生を抑制します

Neobavaisoflavone inhibits osteoclastogenesis through blocking RANKL signalling-mediated TRAF6 and c-Src recruitment and NF-κB, MAPK and Akt pathways.
  • Huiwen Chen
  • Chao Fang
  • Xin Zhi
  • Shaojun Song
  • Yanqiu Gu
  • Xiaofei Chen
  • Jin Cui
  • Yan Hu
  • Weizong Weng
  • Qirong Zhou
  • Yajun Wang
  • Yao Wang
  • Hao Jiang
  • Xiaoqun Li
  • Liehu Cao
  • Xiao Chen
  • Jiacan Su
  • J. Cell. Mol. Med..2020 Jun;doi: 10.1111/jcmm.15543.Epub 2020-06-30.

成人の不眠症障害患者を対象とした lemborexant のプラセボと比較した長期的な有効性と忍容性:第 3 相無作為化臨床試験 SUNRISE 2 の結果

Long-term efficacy and tolerability of lemborexant compared with placebo in adults with insomnia disorder: results from the phase 3 randomized clinical trial SUNRISE 2.
  • Mikko Kärppä
  • Jane Yardley
  • Kate Pinner
  • Gleb Filippov
  • Gary Zammit
  • Margaret Moline
  • Carlos Perdomo
  • Yuichi Inoue
  • Kohei Ishikawa
  • Naoki Kubota
  • Sleep.2020 Jun;zsaa123. doi: 10.1093/sleep/zsaa123.Epub 2020-06-26.

不顕性CMVおよびEBVの脱落は、抑制的抗レトロウイルス療法中の末梢血中のHIV DNA分子多様性の増加と関連している

Subclinical CMV and EBV Shedding is associated with increasing HIV DNA Molecular Diversity in Peripheral Blood during Suppressive Antiretroviral Therapy.
  • Antoine Chaillon
  • Masato Nakazawa
  • Stephen A Rawlings
  • Genevieve Curtin
  • Gemma Caballero
  • Brianna Scott
  • Christy Anderson
  • Sara Gianella
  • J. Virol..2020 Jul;JVI.00927-20. doi: 10.1128/JVI.00927-20.Epub 2020-07-08.