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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

(5-((4-(ピリジン-3-イル)ピリミジン-2-イル)アミノ)-1H-インドール足場を有するメチレンヒドラジン-1-カルボキサミド誘導体の設計、合成および生物学的評価。新規なCDK9阻害剤の可能性

Design, synthesis and biological evaluation of methylenehydrazine-1-carboxamide derivatives with (5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole scaffold: Novel potential CDK9 inhibitors.
  • Hongyu Hu
  • Jun Wu
  • Mingtao Ao
  • Xiaoping Zhou
  • Boqun Li
  • Zhenzhen Cui
  • Tong Wu
  • Lijuan Wang
  • Yuhua Xue
  • Zhen Wu
  • Meijuan Fang
  • Bioorg. Chem..2020 Jun;102:104064. S0045-2068(20)31361-4. doi: 10.1016/j.bioorg.2020.104064.Epub 2020-06-30.

米国メリーランド州ボルチモアのシスジェンダー女性セックスワーカーのコホートにおけるInternalized Sex Work Stigma Scaleの確認的因子分析と構成要件の妥当性

Confirmatory Factor Analysis and Construct Validity of the Internalized Sex Work Stigma Scale among a Cohort of Cisgender Female Sex Workers in Baltimore, Maryland, United States.
  • Catherine Tomko
  • Danielle Friedman Nestadt
  • Saba Rouhani
  • Bradley E Silberzahn
  • Katherine Haney
  • Ju Nyeong Park
  • Noya Galai
  • Carmen H Logie
  • Susan G Sherman
  • J Sex Res.2020 May;:1-11. doi: 10.1080/00224499.2020.1755821.Epub 2020-05-13.

膠芽腫と新たに診断された患者を対象とした、テモゾロミドとの併用、または放射線療法およびテモゾロミドとの併用によるブパルリシブの第I相非盲検多施設共同試験

Phase I, open-label, multicentre study of buparlisib in combination with temozolomide or with concomitant radiation therapy and temozolomide in patients with newly diagnosed glioblastoma.
  • Patrick Yung Wen
  • Jordi A Rodon
  • Warren Mason
  • Joseph T Beck
  • John DeGroot
  • Valerie Donnet
  • David Mills
  • Mona El-Hashimy
  • Mark Rosenthal
  • ESMO Open.2020 Jul;5(4). e000673. doi: 10.1136/esmoopen-2020-000673.

1型糖尿病の小児および青年における低血糖エピソードに対する単純な炭水化物の効果の比較。糖尿病キャンプでの無作為化研究

Comparison of the Effectiveness of Simple Carbohydrates on Hypoglycemic Episodes in Children and Adolescents with Type 1 Diabetes Mellitus: A Randomized Study in a Diabetes Camp.
  • İbrahim Mert Erbaş
  • Ayhan Abacı
  • Ahmet Anık
  • Erdem Şimşek
  • Hale Ünver Tuhan
  • Cemil Koçyiğit
  • Melek Yıldİz
  • Bumin Nuri Dündar
  • Ece Böber
  • Gönül Çatlı
  • Pediatr Diabetes.2020 Jul;doi: 10.1111/pedi.13077.Epub 2020-07-13.

臨床的に定義された痛風患者を対象としたサブタイプ特異的痛風感受性遺伝子座とその選択圧力の富化、およびサブタイプのゲノムワイドメタアナリシスによって同定された

Subtype-specific gout susceptibility loci and enrichment of selection pressure on and identified by subtype genome-wide meta-analyses of clinically defined gout patients.
  • Akiyoshi Nakayama
  • Masahiro Nakatochi
  • Yusuke Kawamura
  • Ken Yamamoto
  • Hirofumi Nakaoka
  • Seiko Shimizu
  • Toshihide Higashino
  • Teruhide Koyama
  • Asahi Hishida
  • Kiyonori Kuriki
  • Miki Watanabe
  • Toru Shimizu
  • Keiko Ooyama
  • Hiroshi Ooyama
  • Mitsuo Nagase
  • Yuji Hidaka
  • Daisuke Matsui
  • Takashi Tamura
  • Takeshi Nishiyama
  • Chisato Shimanoe
  • Sakurako Katsuura-Kamano
  • Naoyuki Takashima
  • Yuya Shirai
  • Makoto Kawaguchi
  • Mikiya Takao
  • Ryo Sugiyama
  • Yuzo Takada
  • Takahiro Nakamura
  • Hiroshi Nakashima
  • Masashi Tsunoda
  • Inaho Danjoh
  • Atsushi Hozawa
  • Kazuyoshi Hosomichi
  • Yu Toyoda
  • Yu Kubota
  • Tappei Takada
  • Hiroshi Suzuki
  • Blanka Stiburkova
  • Tanya J Major
  • Tony R Merriman
  • Nagato Kuriyama
  • Haruo Mikami
  • Toshiro Takezaki
  • Keitaro Matsuo
  • Sadao Suzuki
  • Tatsuo Hosoya
  • Yoichiro Kamatani
  • Michiaki Kubo
  • Kimiyoshi Ichida
  • Kenji Wakai
  • Ituro Inoue
  • Yukinori Okada
  • Nariyoshi Shinomiya
  • Hirotaka Matsuo
  • Ann. Rheum. Dis..2020 05;79(5):657-665. annrheumdis-2019-216644. doi: 10.1136/annrheumdis-2019-216644.Epub 2020-04-01.

ヒト赤血球のヒ素とセレン酸塩の取り込みと隔離。セレノビス(S-グルタチオニル)アルジニウムイオンのヒト細胞内での形成の証拠

Human Red Blood Cell Uptake and Sequestration of Arsenite and Selenite: Evidence of Seleno-bis(S-glutathionyl) Arsinium Ion Formation in Human Cells.
  • Gurnit Kaur
  • Warda Javed
  • Olena Ponomarenko
  • Kamran Shekh
  • Diane P Swanlund
  • Janet R Zhou
  • Kelly L Summers
  • Angela Casini
  • Margot Wenzel
  • Joseph R Casey
  • Emmanuelle Cordat
  • Ingrid J Pickering
  • Graham N George
  • Elaine M Leslie
  • Biochem. Pharmacol..2020 Jul;:114141. S0006-2952(20)30377-4. doi: 10.1016/j.bcp.2020.114141.Epub 2020-07-08.

赤血球あたりの胎児ヘモグロビン定量により、鎌状赤血球症における保護閾値を決定することができる

Fetal hemoglobin quantification per red blood cell allows to determine protective thresholds in sickle cell disease.
  • Nicolas Hebert
  • Marie Georgine Rakotoson
  • Gwellaouen Bodivit
  • Etienne Audureau
  • Laura Bencheikh
  • Laurent Kiger
  • Nadia Oubaya
  • Sadaf Pakdaman
  • Mehdi Sakka
  • Gaetana Di Liberto
  • Philippe Chadebech
  • Benoit Vingert
  • France Pirenne
  • Frédéric Galactéros
  • Marie Cambot
  • Pablo Bartolucci
  • Am. J. Hematol..2020 Jul;doi: 10.1002/ajh.25937.Epub 2020-07-18.

乳様突起気管置換術は顔面管の寸法と顔面鼓膜セグメントと粘膜の距離、および側方半円管と粘膜の距離に影響を与えるか?

Does Mastoid Pneumatization Affect Facial Canal Dimensions and Distances of Facial Tympanic Segment-Scutum and Lateral Semicircular Canal-Scutum?
  • Mikail Inal
  • Nuray Bayar Muluk
  • Neşe Asal
  • Mehmet Hamdi Şahan
  • Gökçe Şimşek
  • Osman Kürşat Arıkan
  • J Comput Assist Tomogr.2020 May/Jun;44(3):380-385. doi: 10.1097/RCT.0000000000000992.

子宮頸がん患者の生存期間におけるMMP-2、MMP-9、MMP-14、TIMP-1、TIMP-2、およびVEGF-Aの腫瘍性および間質性発現:競合リスク分析

Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis.
  • Jordana Maria Azevedo Martins
  • Silvia Helena Rabelo-Santos
  • Maria Cristina do Amaral Westin
  • Luiz Carlos Zeferino
  • BMC Cancer.2020 Jul;20(1):660. 10.1186/s12885-020-07150-3. doi: 10.1186/s12885-020-07150-3.Epub 2020-07-15.

PDGFA-associated protein 1は、成熟Bリンパ球をストレスによる細胞死から保護し、抗体遺伝子の多様化を促進します

PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification.
  • Verónica Delgado-Benito
  • Maria Berruezo-Llacuna
  • Robert Altwasser
  • Wiebke Winkler
  • Devakumar Sundaravinayagam
  • Sandhya Balasubramanian
  • Marieta Caganova
  • Robin Graf
  • Ali Rahjouei
  • Marie-Thérèse Henke
  • Madlen Driesner
  • Lisa Keller
  • Alessandro Prigione
  • Martin Janz
  • Altuna Akalin
  • Michela Di Virgilio
  • J. Exp. Med..2020 Oct;217(10). e20200137. doi: 10.1084/jem.20200137.

肺癌治療のためのシスプラチンを担持したキトサンアルギン酸ナノポーラスキャリアの開発、体外での特性評価、および生体内毒性評価

Development, In Vitro Characterization, and In Vivo Toxicity Evaluation of Chitosan-Alginate Nanoporous Carriers Loaded with Cisplatin for Lung Cancer Treatment.
  • Mo'tasem M Alsmadi
  • Rana M Obaidat
  • Mohammad Alnaief
  • Borhan Aldeen Albiss
  • Nabil Hailat
  • AAPS PharmSciTech.2020 Jul;21(5):191. 10.1208/s12249-020-01735-8. doi: 10.1208/s12249-020-01735-8.Epub 2020-07-13.

フードパントリー利用者の喫煙有病率と食料不安に対する禁煙プログラムの影響 - 実用的クラスター無作為化比較試験のための研究プロトコル

Impact of a smoking cessation program on smoking prevalence and food security among food pantry users - a study protocol for a pragmatic cluster randomised controlled trial.
  • Anja Simmet
  • Michael Teut
  • Romy Schleicher
  • Andreas Bschaden
  • Nanette Stroebele-Benschop
  • BMC Public Health.2020 Jul;20(1):1124. 10.1186/s12889-020-09232-0. doi: 10.1186/s12889-020-09232-0.Epub 2020-07-17.

経鼻的フルニソリドは、マウスの肺のシリカ粒子によって引き起こされる病理学的変化を抑制します

Intranasal Flunisolide Suppresses Pathological Alterations Caused by Silica Particles in the Lungs of Mice.
  • Tatiana Paula Teixeira Ferreira
  • Januário Gomes Mourão E Lima
  • Francisco Alves Farias-Filho
  • Yago Amigo Pinho Jannini de Sá
  • Ana Carolina Santos de Arantes
  • Fernanda Verdini Guimarães
  • Vinicius de Frias Carvalho
  • Cory Hogaboam
  • John Wallace
  • Marco Aurélio Martins
  • Patrícia Machado Rodrigues E Silva
  • Front Endocrinol (Lausanne).2020;11:388. doi: 10.3389/fendo.2020.00388.Epub 2020-06-17.

体外ガス発生を利用したアンコイルド・ライス・ストローの品質向上およびラムナル消化率向上のためのラムナル・クラブトリー陰性酵母とクラブトリー陽性酵母の比較効果

Comparison Effects of Ruminal Crabtree-Negative Yeasts and Crabtree-Positive Yeasts for Improving Ensiled Rice Straw Quality and Ruminal Digestion Using In Vitro Gas Production.
  • Chanon Suntara
  • Anusorn Cherdthong
  • Suthipong Uriyapongson
  • Metha Wanapat
  • Pin Chanjula
  • J Fungi (Basel).2020 Jul;6(3). E109. doi: 10.3390/jof6030109.Epub 2020-07-15.

豚糞尿の高固形分嫌気性消化に及ぼすナノバブル水の効果。消化安定性、メタン生成性能、および関連メカニズムに焦点を当てる

Effect of nano-bubble water on high solid anaerobic digestion of pig manure: Focus on digestion stability, methanogenesis performance and related mechanisms.
  • Yujie Fan
  • Zhongfang Lei
  • Xiaojing Yang
  • Motoyoshi Kobayashi
  • Yasuhisa Adachi
  • Zhenya Zhang
  • Kazuya Shimizu
  • Bioresour. Technol..2020 Jul;315:123793. S0960-8524(20)31065-8. doi: 10.1016/j.biortech.2020.123793.Epub 2020-07-08.

抗酸化剤とプレバイオティクスの併用は、どちらか一方の単剤療法よりも、去勢雄性ラットの認知機能改善に大きな効果を発揮します

A combination of an antioxidant with a prebiotic exerts greater efficacy than either as a monotherapy on cognitive improvement in castrated-obese male rats.
  • Titikorn Chunchai
  • Puntarik Keawtep
  • Apiwan Arinno
  • Napatsorn Saiyasit
  • Dillon Prus
  • Nattayaporn Apaijai
  • Wasana Pratchayasakul
  • Nipon Chattipakorn
  • Siriporn C Chattipakorn
  • Metab Brain Dis.2020 Jul;10.1007/s11011-020-00603-5. doi: 10.1007/s11011-020-00603-5.Epub 2020-07-16.

全身照射と血液または骨髄移植後の乳がんリスク。血液または骨髄移植生存者の研究報告

Total Body Irradiation and Risk of Breast Cancer After Blood or Marrow Transplantation: A Blood or Marrow Transplantation Survivor Study Report.
  • Andrew M McDonald
  • Yanjun Chen
  • Jessica Wu
  • Lindsey Hageman
  • Liton Francisco
  • Michelle Kung
  • F Lennie Wong
  • Emily Ness
  • Wendy Landier
  • Kevin Battles
  • Donna Salzman
  • Daniel J Weisdorf
  • Stephen J Forman
  • Mukta Arora
  • Saro H Armenian
  • Smita Bhatia
  • J. Clin. Oncol..2020 Jul;:JCO2000231. doi: 10.1200/JCO.20.00231.Epub 2020-07-16.

嗅球摘出マウスの視床下部におけるドパミンD受容体の過敏性

Dopamine D receptor supersensitivity in the hypothalamus of olfactory bulbectomized mice.
  • Kohei Takahashi
  • Osamu Nakagawasai
  • Takeharu Nakajima
  • Myu Okubo
  • Yuki Nishimura
  • Wakana Sakuma
  • Ryota Yamagata
  • Wataru Nemoto
  • Kazuya Miyagawa
  • Kazuhiro Kurokawa
  • Atsumi Mochida-Saito
  • Minoru Tsuji
  • Hiroshi Takeda
  • Takeshi Tadano
  • Koichi Tan-No
  • Brain Res..2020 Jul;1746:147015. S0006-8993(20)30371-1. doi: 10.1016/j.brainres.2020.147015.Epub 2020-07-13.

閉塞性睡眠時無呼吸と関連した術後重症イベント。麻酔と睡眠医学の閉塞性睡眠時無呼吸のレジストリの学会からの結果

Postoperative Critical Events Associated With Obstructive Sleep Apnea: Results From the Society of Anesthesia and Sleep Medicine Obstructive Sleep Apnea Registry.
  • Norman Bolden
  • Karen L Posner
  • Karen B Domino
  • Dennis Auckley
  • Jonathan L Benumof
  • Seth T Herway
  • David Hillman
  • Shawn L Mincer
  • Frank Overdyk
  • David J Samuels
  • Lindsay L Warner
  • Toby N Weingarten
  • Frances Chung
  • Anesth. Analg..2020 Jul;doi: 10.1213/ANE.0000000000005005.Epub 2020-07-14.

ヒト羊膜間葉系幹細胞は、アポトーシスと酸化ストレスを抑制することで、ブスルファン誘発性精巣毒性を有するマウスの精子形成を回復させる

Human amnion mesenchymal stem cells restore spermatogenesis in mice with busulfan-induced testis toxicity by inhibiting apoptosis and oxidative stress.
  • Chunfeng Qian
  • Qingxia Meng
  • Jiafeng Lu
  • Liya Zhang
  • Hong Li
  • Boxian Huang
  • Stem Cell Res Ther.2020 Jul;11(1):290. 10.1186/s13287-020-01803-7. doi: 10.1186/s13287-020-01803-7.Epub 2020-07-16.

神経炎症はレビー小体型疾患およびα-シヌクレイン遺伝子導入モデルにおけるT細胞の浸潤と関連している

Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models.
  • Michiyo Iba
  • Changyoun Kim
  • Michelle Sallin
  • Somin Kwon
  • Anjali Verma
  • Cassia Overk
  • Robert A Rissman
  • Ranjan Sen
  • Jyoti Misra Sen
  • Eliezer Masliah
  • J Neuroinflammation.2020 Jul;17(1):214. 10.1186/s12974-020-01888-0. doi: 10.1186/s12974-020-01888-0.Epub 2020-07-17.

単純ヘルペスウイルス2型は神経成長因子に依存した感染時の神経突起の伸長反発に対抗する

Herpes Simplex Virus Type 2 Counteracts Neurite Outgrowth Repulsion During Infection In A Nerve Growth Factor-Dependent Manner.
  • Kai A Kropp
  • Alberto Domingo López-Muñoz
  • Birgit Ritter
  • Rocío Martín
  • Alberto Rastrojo
  • Sangar Srivaratharajan
  • Katinka Döhner
  • Akshay Dhingra
  • Julia S Czechowicz
  • Claus-Henning Nagel
  • Beate Sodeik
  • Antonio Alcami
  • Abel Viejo-Borbolla
  • J. Virol..2020 Jul;JVI.01370-20. doi: 10.1128/JVI.01370-20.Epub 2020-07-15.

播種性Talaromyces marneffei感染症は、STAT3変異を有する乳児に多発性腸管穿孔とびまん性肝肉芽腫性炎症を呈した症例である

Disseminated Talaromyces marneffei infection presenting as multiple intestinal perforations and diffuse hepatic granulomatous inflammation in an infant with STAT3 mutation: a case report.
  • Mianluan Pan
  • Ye Qiu
  • Wen Zeng
  • Shudan Tang
  • Xuan Wei
  • Jianquan Zhang
  • BMC Infect. Dis..2020 Jun;20(1):394. 10.1186/s12879-020-05113-4. doi: 10.1186/s12879-020-05113-4.Epub 2020-06-03.

良性適応の子宮摘出術におけるシングルサイトロボット、マルチポートロボット、従来の腹腔鏡下手術の手術成績の比較

A Comparison of Surgical Outcomes between Single-Site Robotic, Multiport Robotic and Conventional Laparoscopic Techniques in Performing Hysterectomy for Benign Indications.
  • Natasha Gupta
  • D O Miranda Blevins
  • Jenny Holcombe
  • Robert Scott Furr
  • Gynecol Minim Invasive Ther.2020 Apr-Jun;9(2):59-63. GMIT-9-59. doi: 10.4103/GMIT.GMIT_68_19.Epub 2020-04-28.

高齢化社会を迎えた日本における最近の精巣悪性腫瘍の動向:2012年~2015年の病院別がん登録データを用いた大規模研究

Recent malignant testicular tumor trend in Japan, a country with an aging population: a large-scale study of 2012-2015 hospital-based cancer registry data.
  • Kosuke Kojo
  • Koji Kawai
  • Takashi Kawahara
  • Tomokazu Kimura
  • Shuya Kandori
  • Yoshiyuki Nagumo
  • Satoshi Nitta
  • Takahiro Kojima
  • Ayako Okuyama
  • Takahiro Higashi
  • Hiroyuki Nishiyama
  • Jpn. J. Clin. Oncol..2020 Jul;hyaa110. doi: 10.1093/jjco/hyaa110.Epub 2020-07-06.

腎移植患者における高悪性度扁平上皮内病変のリスクは、免疫力のない対照者と比較して、肛門の高悪性度扁平上皮内病変のリスクが高い

Risk of anal high-grade squamous intraepithelial lesions among renal transplant recipients compared with immunocompetent controls.
  • H K Larsen
  • M Hædersdal
  • L T Thomsen
  • R Hertzum-Larsen
  • T T Lok
  • J Bonde
  • S S Sørensen
  • J M Hansen
  • J M Palefsky
  • S K Kjær
  • Clin. Infect. Dis..2020 Jun;ciaa781. doi: 10.1093/cid/ciaa781.Epub 2020-06-16.

急性骨髄性白血病患者の芽球細胞におけるScl転写因子複合体タンパク質発現パターンとATRA誘導分化に対するLiClの効果との関係の解析

Analysis of the relationship between Scl transcription factor complex protein expression patterns and the effects of LiCl on ATRA-induced differentiation in blast cells from patients with acute myeloid leukemia.
  • Anna M Rice
  • Kathleen M Holtz
  • Judith Karp
  • Sandra Rollins
  • Alan C Sartorelli
  • Leuk. Res..2004 Nov;28(11):1227-37. S0145212604001237. doi: 10.1016/j.leukres.2004.03.017.