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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

ラット血漿中のタモキシフェンとスルホラファンの同時測定のためのハイスループット生体分析UPLC-MS/MS法の開発と検証。経口薬物動態試験への応用

Development and validation of a high throughput bioanalytical UPLC-MS/MS method for simultaneous determination of tamoxifen and sulphoraphane in rat plasma: Application to an oral pharmacokinetic study.
  • Bharti Mangla
  • Ozair Alam
  • Rehan Abdur Rub
  • Muzaffar Iqbal
  • Archu Singh
  • Kuldeep Singh Patel
  • Kanchan Kohli
  • J. Chromatogr. B Analyt. Technol. Biomed. Life Sci..2020 Jul;1152:122260. S1570-0232(20)30645-0. doi: 10.1016/j.jchromb.2020.122260.Epub 2020-07-06.

マレーシア・ボルネオ島のLower Kinabatangan Wildlife Sanctuary (LKWS)の河岸林における霊長類の国勢調査のための赤外線カメラと目視による計数方法の比較評価

A comparative evaluation of thermal camera and visual counting methods for primate census in a riparian forest at the Lower Kinabatangan Wildlife Sanctuary (LKWS), Malaysian Borneo.
  • Amaziasizamoria Jumail
  • Thor-Seng Liew
  • Milena Salgado-Lynn
  • Kimberly M Fornace
  • Danica J Stark
  • Primates.2020 Jun;10.1007/s10329-020-00837-y. doi: 10.1007/s10329-020-00837-y.Epub 2020-06-22.

新規に診断された膠芽腫におけるベバシズマブに対する早期反応を予測するための動的造影灌流MRIの価値。ACRIN 6686多施設共同試験の結果

Value of Dynamic Contrast Perfusion MRI to Predict Early Response to Bevacizumab in Newly Diagnosed Glioblastoma: Results from ACRIN 6686 Multi-Center Trial.
  • Kathleen M Schmainda
  • Melissa A Prah
  • Helga Marques
  • Eunhee Kim
  • Daniel P Barboriak
  • Jerrold L Boxerman
  • Neuro-oncology.2020 Jul;noaa167. doi: 10.1093/neuonc/noaa167.Epub 2020-07-17.

オランダでの情報に基づく公衆衛生上の意思決定のための迅速なSARS-CoV-2全ゲノムシークエンシングと解析

Rapid SARS-CoV-2 whole-genome sequencing and analysis for informed public health decision-making in the Netherlands.
  • Bas B Oude Munnink
  • David F Nieuwenhuijse
  • Mart Stein
  • Áine O'Toole
  • Manon Haverkate
  • Madelief Mollers
  • Sandra K Kamga
  • Claudia Schapendonk
  • Mark Pronk
  • Pascal Lexmond
  • Anne van der Linden
  • Theo Bestebroer
  • Irina Chestakova
  • Ronald J Overmars
  • Stefan van Nieuwkoop
  • Richard Molenkamp
  • Annemiek A van der Eijk
  • Corine GeurtsvanKessel
  • Harry Vennema
  • Adam Meijer
  • Andrew Rambaut
  • Jaap van Dissel
  • Reina S Sikkema
  • Aura Timen
  • Marion Koopmans
  • Nat. Med..2020 Jul;10.1038/s41591-020-0997-y. doi: 10.1038/s41591-020-0997-y.Epub 2020-07-16.

ダルナビルは/種複合体の成長を阻害し,抗真菌薬に対するバイオフィルムの感受性を高めた.

Darunavir inhibits / species complex growth and increases the susceptibility of biofilms to antifungal drugs.
  • Raimunda Sâmia Nogueira Brilhante
  • José Alexandre Telmos Silva
  • Géssica Dos Santos Araújo
  • Vandbergue Santos Pereira
  • Wilker Jose Perez Gotay
  • Jonathas Sales de Oliveira
  • Glaucia Morgana de Melo Guedes
  • Waldemiro Aquino Pereira-Neto
  • Débora de Souza Collares Maia Castelo-Branco
  • Rossana de Aguiar Cordeiro
  • José Júlio Costa Sidrim
  • Marcos Fábio Gadelha Rocha
  • J. Med. Microbiol..2020 Jun;69(6):830-837. doi: 10.1099/jmm.0.001194.

スカンサス×ギガンテウスとゼアメイの葉における低温下でのスクロースリン酸合成酵素(SPS)、スクロース合成酵素(SUS)とその生成物

Sucrose phosphate synthase (SPS), sucrose synthase (SUS) and their products in the leaves of Miscanthus × giganteus and Zea mays at low temperature.
  • Anna Bilska-Kos
  • Jennifer Mytych
  • Szymon Suski
  • Justyna Magoń
  • Piotr Ochodzki
  • Jacek Zebrowski
  • Planta.2020 Jul;252(2):23. 10.1007/s00425-020-03421-2. doi: 10.1007/s00425-020-03421-2.Epub 2020-07-16.

筋浸潤性尿路上皮癌を対象としたNEoadjuvant dos-dense MVAC In cOmbination with durvalumab and tremelimumab: NEMIOの有効性を評価するためのオープンラベル第Ⅱ相試験

Open-label phase II to evaluate the efficacy of NEoadjuvant dose-dense MVAC In cOmbination with durvalumab and tremelimumab in muscle-invasive urothelial carcinoma: NEMIO.
  • Constance Thibault
  • Reza Elaidi
  • Yann-Alexandre Vano
  • Mouna Rouabah
  • Elena Braychenko
  • Imen Helali
  • François Audenet
  • Stéphane Oudard
  • Bull Cancer.2020 Jun;107(5S):eS8-eS15. S0007-4551(20)30281-2. doi: 10.1016/S0007-4551(20)30281-2.

敗血症性ショック生存者の健康関連QOL:ADRENAL試験の6ヵ月追跡調査

Health-related quality of life in survivors of septic shock: 6-month follow-up from the ADRENAL trial.
  • Naomi E Hammond
  • Simon R Finfer
  • Qiang Li
  • Colman Taylor
  • Jeremy Cohen
  • Yaseen Arabi
  • Rinaldo Bellomo
  • Laurent Billot
  • Meg Harward
  • Christopher Joyce
  • Colin McArthur
  • John Myburgh
  • Anders Perner
  • Dorrilyn Rajbhandari
  • Andrew Rhodes
  • Kelly Thompson
  • Steve Webb
  • Balasubramanian Venkatesh
  • Intensive Care Med.2020 Jul;10.1007/s00134-020-06169-1. doi: 10.1007/s00134-020-06169-1.Epub 2020-07-16.

石膏(CaSO-2HO)中のセレン酸塩とセレン酸塩の隔離.単結晶電子常磁性共鳴分光法と放射光X線吸収分光法による研究からの知見

Sequestration of Selenite and Selenate in Gypsum (CaSO·2HO): Insights from the Single-Crystal Electron Paramagnetic Resonance Spectroscopy and Synchrotron X-ray Absorption Spectroscopy Study.
  • Jinru Lin
  • Ning Chen
  • Renfei Feng
  • Mark J Nilges
  • Yongfeng Jia
  • Shaofeng Wang
  • Yuanming Pan
  • Environ. Sci. Technol..2020 03;54(6):3169-3180. doi: 10.1021/acs.est.9b05714.Epub 2020-03-04.

ABS-ZnOナノコンポジットとABS-ZnOマイクロコンポジットで構成された3Dプリント材料の機械的および物理的特性

The Mechanical and Physical Properties of 3D-Printed Materials Composed of ABS-ZnO Nanocomposites and ABS-ZnO Microcomposites.
  • Nectarios Vidakis
  • Markos Petousis
  • Athena Maniadi
  • Emmanuel Koudoumas
  • George Kenanakis
  • Cosmin Romanitan
  • Oana Tutunaru
  • Mirela Suchea
  • John Kechagias
  • Micromachines (Basel).2020 Jun;11(6). E615. doi: 10.3390/mi11060615.Epub 2020-06-25.

子どもの緩和的アウトカム尺度の適応版の顔と内容の妥当性、受容性、および実現可能性。質的パイロット研究

Face and Content Validity, Acceptability, and Feasibility of the Adapted Version of the Children's Palliative Outcome Scale: A Qualitative Pilot Study.
  • Marie Friedel
  • Bénédicte Brichard
  • Sabine Boonen
  • Corinne Tonon
  • Brigitte De Terwangne
  • Dominique Bellis
  • Murielle Mevisse
  • Christine Fonteyne
  • Maud Jaspard
  • Marie Schruse
  • Richard Harding
  • Julia Downing
  • Eve Namisango
  • Jean-Marie Degryse
  • Isabelle Aujoulat
  • J Palliat Med.2020 Jul;doi: 10.1089/jpm.2019.0646.Epub 2020-07-15.

遺伝子組換えマクロファージは、トランスジェニックパーキンQ311X(A)マウスの炎症を起こした脳への標的遺伝子導入を達成する:投与経路の重要性

Genetically modified macrophages accomplish targeted gene delivery to the inflamed brain in transgenic Parkin Q311X(A) mice: importance of administration routes.
  • Matthew J Haney
  • Yuling Zhao
  • James Fay
  • Hwang Duhyeong
  • Mengzhe Wang
  • Hui Wang
  • Zibo Li
  • Yueh Z Lee
  • Mohan K Karuppan
  • Nazira El-Hage
  • Alexander V Kabanov
  • Elena V Batrakova
  • Sci Rep.2020 Jul;10(1):11818. 10.1038/s41598-020-68874-7. doi: 10.1038/s41598-020-68874-7.Epub 2020-07-16.

ゲノムワイドデータを用いたインド西部マハラシュトラ州の部族・カースト集団の人口統計学的歴史に関する新しい知見

Novel insights on demographic history of tribal and caste groups from West Maharashtra (India) using genome-wide data.
  • Guilherme Debortoli
  • Cristina Abbatangelo
  • Francisco Ceballos
  • Cesar Fortes-Lima
  • Heather L Norton
  • Shantanu Ozarkar
  • Esteban J Parra
  • Manjari Jonnalagadda
  • Sci Rep.2020 Jun;10(1):10075. 10.1038/s41598-020-66953-3. doi: 10.1038/s41598-020-66953-3.Epub 2020-06-22.

2,6-ジアミノプリンを用いたUGAナンセンス突然変異の強力な補正剤として使用しています

2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations.
  • Carole Trzaska
  • Séverine Amand
  • Christine Bailly
  • Catherine Leroy
  • Virginie Marchand
  • Evelyne Duvernois-Berthet
  • Jean-Michel Saliou
  • Hana Benhabiles
  • Elisabeth Werkmeister
  • Thierry Chassat
  • Romain Guilbert
  • David Hannebique
  • Anthony Mouray
  • Marie-Christine Copin
  • Pierre-Arthur Moreau
  • Eric Adriaenssens
  • Andreas Kulozik
  • Eric Westhof
  • David Tulasne
  • Yuri Motorin
  • Sylvie Rebuffat
  • Fabrice Lejeune
  • Nat Commun.2020 03;11(1):1509. 10.1038/s41467-020-15140-z. doi: 10.1038/s41467-020-15140-z.Epub 2020-03-20.

必須アミノ酸α-ケト酸アナログの腎虚血再灌流障害に対する抗炎症作用および抗酸化作用について検討した

Anti-inflammatory and antioxidant activity of essential amino acid α-ketoacid analogues against renal ischemia-reperfusion damage in Wistar rats.
  • Concepción Sánchez-Martínez
  • Liliana Torres-González
  • Gabriela Alarcón-Galván
  • Linda E Muñoz-Espinosa
  • Homero Zapata-Chavira
  • Diana Patricia Moreno-Peña
  • Homero Náñez-Terreros
  • Edelmiro Pérez-Rodríguez
  • Lourdes Garza-Ocañas
  • Francisco Javier Guzmán-de la Garza
  • Paula Andrea Cordero
  • Biomedica.2020 06;40(2):336-348. doi: 10.7705/biomedica.4875.Epub 2020-06-15.

プラスミノーゲンアクチベーターインヒビター-1活性の阻害は、視床下部レプチン抵抗性の高脂肪食誘発体重増加の緩和を抑制する

Inhibition of Plasminogen Activator Inhibitor-1 Activation Suppresses High Fat Diet-Induced Weight Gain Alleviation of Hypothalamic Leptin Resistance.
  • Shinichiro Hosaka
  • Tetsuya Yamada
  • Kei Takahashi
  • Takashi Dan
  • Keizo Kaneko
  • Shinjiro Kodama
  • Yoichiro Asai
  • Yuichiro Munakata
  • Akira Endo
  • Hiroto Sugawara
  • Yohei Kawana
  • Junpei Yamamoto
  • Tomohito Izumi
  • Shojiro Sawada
  • Junta Imai
  • Toshio Miyata
  • Hideki Katagiri
  • Front Pharmacol.2020;11:943. doi: 10.3389/fphar.2020.00943.Epub 2020-06-24.

HIVと共に生きる人々の栄養状態と関連因子:ネパール・カトマンズの病院ベースの抗レトロウイルス治療施設における横断的調査からのエビデンス

Nutritional status and the associated factors among people living with HIV: an evidence from cross-sectional survey in hospital based antiretroviral therapy site in Kathmandu, Nepal.
  • Samip Khatri
  • Archana Amatya
  • Binjwala Shrestha
  • BMC Nutr.2020;6:22. 346. doi: 10.1186/s40795-020-00346-7.Epub 2020-06-15.

ビスホスホン酸エステルの合成、抗炎症活性、およびMMP-8およびMMP-9阻害剤としての分子ドッキング研究

Synthesis, antiinflammatory activity, and molecular docking studies of bisphosphonic esters as potential MMP-8 and MMP-9 inhibitors.
  • Abimelek Cortes-Pacheco
  • María Adelina Jiménez-Arellanes
  • Francisco José Palacios-Can
  • José Antonio Valcarcel-Gamiño
  • Rodrigo Said Razo-Hernández
  • María Del Carmen Juárez-Vázquez
  • Adolfo López-Torres
  • Oscar Abelardo Ramírez-Marroquín
  • Beilstein J Org Chem.2020;16:1277-1287. doi: 10.3762/bjoc.16.108.Epub 2020-06-08.

ヒト大脳皮質におけるミエロイド細胞マーカー発現の定量的な免疫組織化学的解析は、解剖学的な文脈に沿ったミクログリアの不均一性を捉えている

Quantitative immunohistochemical analysis of myeloid cell marker expression in human cortex captures microglia heterogeneity with anatomical context.
  • Molly E V Swanson
  • Helen C Murray
  • Brigid Ryan
  • Richard L M Faull
  • Mike Dragunow
  • Maurice A Curtis
  • Sci Rep.2020 Jul;10(1):11693. 10.1038/s41598-020-68086-z. doi: 10.1038/s41598-020-68086-z.Epub 2020-07-16.

皮膚組織工学のための内皮細胞、真皮線維芽細胞、多層ケラチノサイト層のバイオファブリケーション

Biofabrication of endothelial cell, dermal fibroblast, and multilayered keratinocyte layers for skin tissue engineering.
  • Natan Barros
  • Hanjun Kim
  • Marcus J Goudie
  • KangJu Lee
  • Praveen Bandaru
  • Ethan A Banton
  • Einollah Sarikhani
  • Wujin Sun
  • Shiming Zhang
  • Hyun-Jong Cho
  • Martin C Hartel
  • Serge Ostrovidov
  • Samad Ahadian
  • Saber Hussain
  • Nureddin Ashammakhi
  • Mehmet R Dokmeci
  • Rondinelli Donizetti Herculano
  • Junmin Lee
  • Ali Khademhosseini
  • Biofabrication.2020 Jul;doi: 10.1088/1758-5090/aba503.Epub 2020-07-10.

ヒトモノクローナルSARS-CoV抗体によるSARS-CoV-2の交差中和

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.
  • Dora Pinto
  • Young-Jun Park
  • Martina Beltramello
  • Alexandra C Walls
  • M Alejandra Tortorici
  • Siro Bianchi
  • Stefano Jaconi
  • Katja Culap
  • Fabrizia Zatta
  • Anna De Marco
  • Alessia Peter
  • Barbara Guarino
  • Roberto Spreafico
  • Elisabetta Cameroni
  • James Brett Case
  • Rita E Chen
  • Colin Havenar-Daughton
  • Gyorgy Snell
  • Amalio Telenti
  • Herbert W Virgin
  • Antonio Lanzavecchia
  • Michael S Diamond
  • Katja Fink
  • David Veesler
  • Davide Corti
  • Nature.2020 07;583(7815):290-295. 10.1038/s41586-020-2349-y. doi: 10.1038/s41586-020-2349-y.Epub 2020-05-18.

教育研究。高校生と大学生のためのオンライン アルツハイマー教育。無作為化比較試験

Education Research: Online Alzheimer education for high school and college students: A randomized controlled trial.
  • Nabeel Saif
  • Kellyann Niotis
  • Moises Dominguez
  • John F Hodes
  • Michael Woodbury
  • Yasmin Amini
  • George Sadek
  • Olivia Scheyer
  • Emily Caesar
  • Hollie Hristov
  • Newman Knowlton
  • Paige Lee
  • Mark McInnis
  • Richard S Isaacson
  • Neurology.2020 Jul;10.1212/WNL.0000000000009859. doi: 10.1212/WNL.0000000000009859.Epub 2020-07-14.

分光・相互作用・アプローチを用いたミオグロビンの構造と安定性に及ぼすエチレングリコールの効果モノマーはそのポリマーとは異なる

Effects of Ethylene Glycol on the Structure and Stability of Myoglobin Using Spectroscopic, Interaction, and Approaches: Monomer Is Different from Those of Its Polymers.
  • Zahoor Ahmad Parray
  • Faizan Ahmad
  • Md Imtaiyaz Hassan
  • Ikramul Hasan
  • Asimul Islam
  • ACS Omega.2020 Jun;5(23):13840-13850. doi: 10.1021/acsomega.0c01185.Epub 2020-06-02.

療養中の患者のB細胞のハイスループットシングルセルシークエンシングにより、SARS-CoV-2に対する強力な中和抗体が同定された

Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients' B Cells.
  • Yunlong Cao
  • Bin Su
  • Xianghua Guo
  • Wenjie Sun
  • Yongqiang Deng
  • Linlin Bao
  • Qinyu Zhu
  • Xu Zhang
  • Yinghui Zheng
  • Chenyang Geng
  • Xiaoran Chai
  • Runsheng He
  • Xiaofeng Li
  • Qi Lv
  • Hua Zhu
  • Wei Deng
  • Yanfeng Xu
  • Yanjun Wang
  • Luxin Qiao
  • Yafang Tan
  • Liyang Song
  • Guopeng Wang
  • Xiaoxia Du
  • Ning Gao
  • Jiangning Liu
  • Junyu Xiao
  • Xiao-Dong Su
  • Zongmin Du
  • Yingmei Feng
  • Chuan Qin
  • Chengfeng Qin
  • Ronghua Jin
  • X Sunney Xie
  • Cell.2020 07;182(1):73-84.e16. S0092-8674(20)30620-6. doi: 10.1016/j.cell.2020.05.025.Epub 2020-05-18.