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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

低酸素誘導性第1因子シグナル伝達経路における遺伝子のメチル化と発現の差は、乳がん生存者におけるパクリタキセル誘発末梢神経障害と化学療法誘発神経障害性疼痛の前臨床モデルと関連していた

Differential methylation and expression of genes in the hypoxia-inducible factor 1 signaling pathway are associated with paclitaxel-induced peripheral neuropathy in breast cancer survivors and with preclinical models of chemotherapy-induced neuropathic pain.
  • Kord M Kober
  • Man-Cheung Lee
  • Adam Olshen
  • Yvette P Conley
  • Marina Sirota
  • Michael Keiser
  • Marilyn J Hammer
  • Gary Abrams
  • Mark Schumacher
  • Jon D Levine
  • Christine Miaskowski
  • Mol Pain.2020 Jan-Dec;16:1744806920936502. doi: 10.1177/1744806920936502.

乳がん抑制作用を有するキノコ抽出物と化合物:培養がん細胞、腫瘍担持動物を用いた研究、臨床試験からのエビデンス

Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical trials.
  • Jack Ho Wong
  • Tzi Bun Ng
  • Helen Hei Ling Chan
  • Qin Liu
  • Gene Chi Wai Man
  • Chris Zhiyi Zhang
  • Suzhen Guan
  • Charlene Cheuk Wing Ng
  • Evandro Fei Fang
  • Hexiang Wang
  • Fang Liu
  • Xiuyun Ye
  • Krzysztof Rolka
  • Ryno Naude
  • Shuang Zhao
  • Ou Sha
  • Chunman Li
  • Lixin Xia
  • Appl. Microbiol. Biotechnol..2020 Jun;104(11):4675-4703. 10.1007/s00253-020-10476-4. doi: 10.1007/s00253-020-10476-4.Epub 2020-04-09.

また、メタボリックシンドロームモデルマウスの脂肪組織のトランスクリプトーム解析により、疾患発症に関連する遺伝子シグネチャーを同定した

Transcriptome analysis of the adipose tissue in a mouse model of metabolic syndrome identifies gene signatures related to disease pathogenesis.
  • Dimitris Nasias
  • Katerina Dalakoura-Karagkouni
  • Despoina Vassou
  • Giorgos Papagiannakis
  • Ariadni Papadaki
  • Dimitris Kardassis
  • Genomics.2020 Jul;S0888-7543(19)31032-8. doi: 10.1016/j.ygeno.2020.06.053.Epub 2020-07-08.

COMPASS試験では、血栓透過性は吸引血栓摘出術のファーストパス成功と関連している

Clot perviousness is associated with first pass success of aspiration thrombectomy in the COMPASS trial.
  • Maxim Mokin
  • Muhammad Waqas
  • Johanna Fifi
  • Reade De Leacy
  • David Fiorella
  • Elad I Levy
  • Kenneth Snyder
  • Ricardo Hanel
  • Keith Woodward
  • Imran Chaudry
  • Ansaar T Rai
  • Donald Frei
  • Josser E Delgado Almandoz
  • Michael Kelly
  • Adam S Arthur
  • Blaise W Baxter
  • Joey English
  • Italo Linfante
  • Kyle M Fargen
  • Aquilla Turk
  • Adnan H Siddiqui
  • J Mocco
  • J Neurointerv Surg.2020 Jul;neurintsurg-2020-016434. doi: 10.1136/neurintsurg-2020-016434.Epub 2020-07-17.

血管透過性のダウンレギュレーションと炎症性・酸化性障害の保護を介した敗血症関連急性肺・腎障害に対するマンギフェリンの治療効果

Therapeutic effects of mangiferin on sepsis-associated acute lung and kidney injuries via the downregulation of vascular permeability and protection of inflammatory and oxidative damages.
  • Dong Zhang
  • Shasha Han
  • Yue Zhou
  • Boyang Qi
  • Xiaozhi Wang
  • Eur J Pharm Sci.2020 Jun;152:105400. S0928-0987(20)30189-5. doi: 10.1016/j.ejps.2020.105400.Epub 2020-06-12.

前立腺特異抗原値が上昇した高齢男性患者の病理組織学、薬物療法、前立腺悪性腫瘍の予測因子-プロスペクティブ研究

Histopathology, pharmacotherapy, and predictors of prostatic malignancy in elderly male patients with raised prostate-specific antigen levels - A prospective study.
  • Dhinesh Kumar Mathaiyan
  • Satya Prakash Tripathi
  • Jeffrey Pradeep Raj
  • Bodapati Sivaramakrishna
  • Urol Ann.2020 Apr-Jun;12(2):132-137. UA-12-132. doi: 10.4103/UA.UA_68_19.Epub 2020-04-14.

ハイスループット毒素生産戦略と組み合わせたベノミクスアプローチにより、最初のベノミクス由来メラノコルチン受容体アゴニストが同定された

A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists.
  • Steve Reynaud
  • Justyna Ciolek
  • Michel Degueldre
  • Natalie J Saez
  • Ana Filipa Sequeira
  • Yoan Duhoo
  • Joana L A Brás
  • Hervé Meudal
  • Miguel Cabo Díez
  • Victoria Fernández Pedrosa
  • Marion Verdenaud
  • Julia Boeri
  • Oscar Pereira Ramos
  • Frédéric Ducancel
  • Margot Vanden Driessche
  • Rudy Fourmy
  • Aude Violette
  • Grégory Upert
  • Gilles Mourier
  • Annette G Beck-Sickinger
  • Karin Mörl
  • Céline Landon
  • Carlos M G A Fontes
  • Rebeca Miñambres Herráiz
  • Ricardo C Rodríguez de la Vega
  • Steve Peigneur
  • Jan Tytgat
  • Loïc Quinton
  • Edwin De Pauw
  • Renaud Vincentelli
  • Denis Servent
  • Nicolas Gilles
  • J. Med. Chem..2020 Jul;doi: 10.1021/acs.jmedchem.0c00485.Epub 2020-07-16.

希少な進行性前立腺がん変異型-腺扁平上皮がん、多形巨細胞がん、および肉腫性がん:19例の解析

Gene Fusion Characterization of Rare Aggressive Prostate Cancer Variants - Adenosquamous Carcinoma, Pleomorphic Giant Cell Carcinoma, and Sarcomatoid Carcinoma: An Analysis of 19 Cases.
  • Mohamed Alhamar
  • Tudor Vladislav
  • Steven C Smith
  • Yuan Gao
  • Liang Cheng
  • Laura A Favazza
  • Ali M Alani
  • Michael M Ittmann
  • Nicole D Riddle
  • Lisa J Whiteley
  • Nilesh S Gupta
  • Shannon Carskadon
  • Juan C Gomez-Gelvez
  • Dhananjay A Chitale
  • Nallasivam Palanisamy
  • Ondrej Hes
  • Kiril Trpkov
  • Sean R Williamson
  • Histopathology.2020 Jul;doi: 10.1111/his.14205.Epub 2020-07-08.

逆相高速液体クロマトグラフィーとパルスアンペロメトリック検出を組み合わせた、白人参中の6つの非極性ジンセノサイドの同時定量

Simultaneous quantification of six nonpolar ginsenosides in white ginseng by reverse-phase high-performance liquid chromatography coupled with integrated pulsed amperometric detection.
  • Hyeyoung Song
  • Kyung-Won Song
  • Seon-Pyo Hong
  • J Ginseng Res.2020 Jul;44(4):563-569. S1226-8453(19)30001-6. doi: 10.1016/j.jgr.2019.07.002.Epub 2019-07-26.

酸性スフィンゴミエリン酵素の直接かつ特異的な阻害剤である低分子ARC39のin vitroでの特性評価

Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase in vitro.
  • Eyad Naser
  • Stephanie Kadow
  • Fabian Schumacher
  • Zainelabdeen H Mohamed
  • Christian Kappe
  • Gabriele Hessler
  • Barbara Pollmeier
  • Burkhard Kleuser
  • Christoph Arenz
  • Katrin Anne Becker
  • Erich Gulbins
  • Alexander Carpinteiro
  • J. Lipid Res..2020 Jun;61(6):896-910. jlr.RA120000682. doi: 10.1194/jlr.RA120000682.Epub 2020-03-10.

血漿中および気管支肺胞液中の IL-17A および IL-35 のレベルの上昇は、非小細胞肺がん患者におけるチェックポイント阻害剤肺炎と関連している

Elevated levels of IL-17A and IL-35 in plasma and bronchoalveolar lavage fluid are associated with checkpoint inhibitor pneumonitis in patients with non-small cell lung cancer.
  • Yi Na Wang
  • Dan Feng Lou
  • Dan Yang Li
  • Wei Jiang
  • Jing Yin Dong
  • Wei Gao
  • Hong Chao Chen
  • Oncol Lett.2020 Jul;20(1):611-622. OL-0-0-11618. doi: 10.3892/ol.2020.11618.Epub 2020-05-13.

緑膿菌を標的とした工学的低分子ピリンの免疫増強:免疫情報学的調査と積極的な免疫化の組み合わせ

Immunopotentiation of the engineered low-molecular-weight pilin targeting Pseudomonas aeruginosa: A combination of immunoinformatics investigation and active immunization.
  • Yasaman Ahmadbeigi
  • Alireza Salimi Chirani
  • Neda Soleimani
  • Mehdi Mahdavi
  • Mehdi Goudarzi
  • Mol. Immunol..2020 Aug;124:70-82. S0161-5890(20)30350-3. doi: 10.1016/j.molimm.2020.05.009.Epub 2020-06-12.

膵頭十二指腸摘術後の術前赤血球平均コルプスキュラー容積と感染症合併症との間に有意な関連があることを示した

Significant association between the preoperative erythrocyte mean corpuscular volume and infectious complications after pancreaticoduodenectomy.
  • Katsunori Sakamoto
  • Kohei Ogawa
  • Hitoshi Inoue
  • Mikiya Shine
  • Takashi Matsui
  • Yusuke Nishi
  • Takeshi Utsunomiya
  • Kei Tamura
  • Akihiro Takai
  • Yasutsugu Takada
  • Surg. Today.2020 Jul;10.1007/s00595-020-02083-7. doi: 10.1007/s00595-020-02083-7.Epub 2020-07-17.

サハラ以南のアフリカにおける低窒素投入条件でのトウモロコシ収量に対する気候変動の影響をモデル化する

Modelling climate change impacts on maize yields under low nitrogen input conditions in sub-Saharan Africa.
  • G N Falconnier
  • M Corbeels
  • K J Boote
  • F Affholder
  • M Adam
  • D S MacCarthy
  • A C Ruane
  • C Nendel
  • A M Whitbread
  • E Justes
  • L R Ahuja
  • F M Akinseye
  • I N Alou
  • K A Amouzou
  • S S Anapalli
  • C Baron
  • B Basso
  • F Baudron
  • P Bertuzzi
  • A J Challinor
  • Y Chen
  • D Deryng
  • M L Elsayed
  • B Faye
  • T Gaiser
  • M Galdos
  • S Gayler
  • E Gerardeaux
  • M Giner
  • B Grant
  • G Hoogenboom
  • E S Ibrahim
  • B Kamali
  • K C Kersebaum
  • S H Kim
  • M van der Laan
  • L Leroux
  • J I Lizaso
  • B Maestrini
  • E A Meier
  • F Mequanint
  • A Ndoli
  • C H Porter
  • E Priesack
  • D Ripoche
  • T Sida
  • U Singh
  • W Smith
  • A Srivastava
  • S Sinha
  • F Tao
  • P J Thorburn
  • D Timlin
  • B Traore
  • T Twine
  • H Webber
  • Glob Chang Biol.2020 Jul;doi: 10.1111/gcb.15261.Epub 2020-07-06.

膀胱癌に対する根治的膀胱摘出術後の補助化学療法のタイミングが患者の生存に及ぼす影響

Impact of timing of adjuvant chemotherapy following radical cystectomy for bladder cancer on patient survival.
  • Camilla M Grunewald
  • Alina Henn
  • Matthew D Galsky
  • Elizabeth R Plimack
  • Lauren C Harshman
  • Evan Y Yu
  • Simon J Crabb
  • Sumanta K Pal
  • Ajjai Shivaram Alva
  • Thomas Powles
  • Ugo De Giorgi
  • Neeraj Agarwal
  • Aristotelis Bamias
  • Sylvain Ladoire
  • Andrea Necchi
  • Ulka N Vaishampayan
  • Cora N Sternberg
  • Joaquim Bellmunt
  • Jack Baniel
  • Guenter Niegisch
  • Urol. Oncol..2020 Jul;S1078-1439(20)30276-3. doi: 10.1016/j.urolonc.2020.06.008.Epub 2020-07-10.

NPHS1およびTNFSF15における共通のリスクバリアントは、小児ステロイド感受性ネフローゼ症候群と関連している

Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome.
  • Xiaoyuan Jia
  • Tomohiko Yamamura
  • Rasheed Gbadegesin
  • Michelle T McNulty
  • Kyuyong Song
  • China Nagano
  • Yuki Hitomi
  • Dongwon Lee
  • Yoshihiro Aiba
  • Seik-Soon Khor
  • Kazuko Ueno
  • Yosuke Kawai
  • Masao Nagasaki
  • Eisei Noiri
  • Tomoko Horinouchi
  • Hiroshi Kaito
  • Riku Hamada
  • Takayuki Okamoto
  • Koichi Kamei
  • Yoshitsugu Kaku
  • Rika Fujimaru
  • Ryojiro Tanaka
  • Yuko Shima
  • Jiwon Baek
  • Hee Gyung Kang
  • Il-Soo Ha
  • Kyoung Hee Han
  • Eun Mi Yang
  • Asiri Abeyagunawardena
  • Brandon Lane
  • Megan Chryst-Stangl
  • Christopher Esezobor
  • Adaobi Solarin
  • Claire Dossier
  • Georges Deschênes
  • Marina Vivarelli
  • Hanna Debiec
  • Kenji Ishikura
  • Masafumi Matsuo
  • Kandai Nozu
  • Pierre Ronco
  • Hae Il Cheong
  • Matthew G Sampson
  • Katsushi Tokunaga
  • Kazumoto Iijima
  • Kidney Int..2020 Jun;S0085-2538(20)30639-6. doi: 10.1016/j.kint.2020.05.029.Epub 2020-06-14.

HIV 感染症患者におけるグローバルな炎症マーカーとして H-NMR で評価された糖タンパク質プロファイル。プロスペクティブ研究

Glycoprotein Profile Assessed by H-NMR as a Global Inflammation Marker in Patients with HIV Infection. A Prospective Study.
  • Ana-Irene Malo
  • Anna Rull
  • Josefa Girona
  • Pere Domingo
  • Rocío Fuertes-Martín
  • Núria Amigó
  • Cèlia Rodríguez-Borjabad
  • Neus Martínez-Micaelo
  • Manuel Leal
  • Joaquim Peraire
  • Xavier Correig
  • Francesc Vidal
  • Lluis Masana
  • J Clin Med.2020 May;9(5). E1344. doi: 10.3390/jcm9051344.Epub 2020-05-04.