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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

大腿骨セグメント欠損に対するMasquelet手技の第II期における髄腔内爪と人工関節への線維性支柱移植の追加。手技のヒント

Adding a Fibular Strut Allograft to Intramedullary Nail and Cancellous Autograft During Stage II of the Masquelet Technique for Segmental Femur Defects: A Technique Tip.
  • Omar Ramos
  • Michael Mariorenzi
  • Joey P Johnson
  • Roman A Hayda
  • J Am Acad Orthop Surg Glob Res Rev.2020 Jul;4(7):e1900179. 01979360-202007000-00006. doi: 10.5435/JAAOSGlobal-D-19-00179.

インドネシアの土壌菌、Talaromyces pinophilusに由来するPlasmodium falciparum dihydroorotate dehydrogenaseに対して活性な微生物阻害剤 BioMCC-f.T.3979

Microbial inhibitors active against Plasmodium falciparum dihydroorotate dehydrogenase derived from an Indonesian soil fungus, Talaromyces pinophilus BioMCC-f.T.3979.
  • Amila Pramisandi
  • Kazuyuki Dobashi
  • Mihoko Mori
  • Kenichi Nonaka
  • Atsuko Matsumoto
  • Toshiyuki Tokiwa
  • Mayuka Higo
  • Kristiningrum
  • Eri Amalia
  • Arif Nurkanto
  • Daniel Ken Inaoka
  • Danang Waluyo
  • Kiyoshi Kita
  • Tomoyoshi Nozaki
  • Satoshi Ōmura
  • Kazuro Shiomi
  • J. Gen. Appl. Microbiol..2020 Jul;doi: 10.2323/jgam.2019.11.007.Epub 2020-07-14.

ヒトフィブロネクチンのエキストラドメインAとHPV16/18 E7ウイルス抗原との融合タンパク質からなるHPV16/18遺伝子型に対する二価ワクチンの開発

Bivalent therapeutic vaccine against HPV16/18 genotypes consisting of a fusion protein between the extra domain A from human fibronectin and HPV16/18 E7 viral antigens.
  • Laura Arribillaga
  • Iciar Echeverria
  • Viriginia Belsue
  • Timothy Gomez
  • Teresa Lozano
  • Noelia Casares
  • Lorea Villanueva
  • Sonia Domingos-Pereira
  • Pedro J Romero
  • Denise Nardelli-Haefliger
  • Sandra Hervás-Stubbs
  • Pablo Sarobe
  • María Josefa Rodriguez
  • José L Carrascosa
  • Thomas Zürcher
  • Juan José Lasarte
  • J Immunother Cancer.2020 06;8(1). e000704. doi: 10.1136/jitc-2020-000704.

放射線は、RAW 264.7細胞およびマウス骨髄由来マクロファージの細胞骨格および溶解酵素を制御することにより、破骨細胞形成を変化させる

Radiation alters osteoclastogenesis by regulating the cytoskeleton and lytic enzymes in RAW 264.7 cells and mouse bone marrow-derived macrophages.
  • Ling Tong
  • Yuyang Wang
  • Jianping Wang
  • Feilong He
  • Jianglong Zhai
  • Jiangtao Bai
  • Guoying Zhu
  • Int. J. Radiat. Biol..2020 Jul;:1-26. doi: 10.1080/09553002.2020.1798542.Epub 2020-07-20.

空間的に構造化された集団における感染症の発生規模は、局所的な伝播と長距離分散のトレードオフが駆動している

Trade-off between local transmission and long-range dispersal drives infectious disease outbreak size in spatially structured populations.
  • Elisa Benincà
  • Thomas Hagenaars
  • Gert Jan Boender
  • Jan van de Kassteele
  • Michiel van Boven
  • PLoS Comput. Biol..2020 Jul;16(7):e1008009. PCOMPBIOL-D-19-01465. doi: 10.1371/journal.pcbi.1008009.Epub 2020-07-06.

分数的要因設計と中央複合設計の組み合わせを用いた、魚類副産物からのうま味成分の超音波支援酵素抽出条件の最適化

Optimisation of ultrasound-assisted enzymatic extraction conditions of umami compounds from fish by-products using the combination of fractional factorial design and central composite design.
  • Fabrice Bruno Siewe
  • Tanaji G Kudre
  • Bhaskar Narayan
  • Food Chem.2020 Jul;334:127498. S0308-8146(20)31360-1. doi: 10.1016/j.foodchem.2020.127498.Epub 2020-07-10.

化学感覚細胞由来のアセチルコリンは気管粘膜クリアランスをウイルス性ホルミルペプチドに応答して駆動する

Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides.
  • Alexander Perniss
  • Shuya Liu
  • Brett Boonen
  • Maryam Keshavarz
  • Anna-Lena Ruppert
  • Thomas Timm
  • Uwe Pfeil
  • Aichurek Soultanova
  • Soumya Kusumakshi
  • Lucas Delventhal
  • Öznur Aydin
  • Martina Pyrski
  • Klaus Deckmann
  • Torsten Hain
  • Nadine Schmidt
  • Christa Ewers
  • Andreas Günther
  • Günter Lochnit
  • Vladimir Chubanov
  • Thomas Gudermann
  • Johannes Oberwinkler
  • Jochen Klein
  • Katsuhiko Mikoshiba
  • Trese Leinders-Zufall
  • Stefan Offermanns
  • Burkhard Schütz
  • Ulrich Boehm
  • Frank Zufall
  • Bernd Bufe
  • Wolfgang Kummer
  • Immunity.2020 Apr;52(4):683-699.e11. S1074-7613(20)30118-7. doi: 10.1016/j.immuni.2020.03.005.

AMPK依存的にHDAC8をリン酸化することでPGM1の発現が促進され、グルコース飢餓下での肺癌細胞の生存が促進されることを明らかにした

AMPK-dependent phosphorylation of HDAC8 triggers PGM1 expression to promote lung cancer cell survival under glucose starvation.
  • Yanping Li
  • Ronghui Liang
  • Mingming Sun
  • Zhen Li
  • Hao Sheng
  • Jiyan Wang
  • Pengjuan Xu
  • Shuangping Liu
  • Wancai Yang
  • Bin Lu
  • Shuai Zhang
  • Changliang Shan
  • Cancer Lett..2020 May;478:82-92. S0304-3835(20)30126-9. doi: 10.1016/j.canlet.2020.03.007.Epub 2020-03-20.

JEN1とADY2の欠失により、異種乳酸脱水素酵素を発現するサッカロミセス・セレビシエのキシロース培地での乳酸収量が減少することを明らかにした

Deletion of JEN1 and ADY2 reduces lactic acid yield from an engineered Saccharomyces cerevisiae, in xylose medium, expressing a heterologous lactate dehydrogenase.
  • Timothy L Turner
  • Stephan Lane
  • Lahiru N Jayakody
  • Guo-Chang Zhang
  • Heejin Kim
  • Whiyeon Cho
  • Yong-Su Jin
  • FEMS Yeast Res..2019 09;19(6). foz050. doi: 10.1093/femsyr/foz050.

遺伝情報を公表するのはいつで、誰の責任なのか?BRCA遺伝性がんリスクの開示に関する医療専門家の見解についての横断的質的研究

When to break the news and whose responsibility is it? A cross-sectional qualitative study of health professionals' views regarding disclosure of BRCA genetic cancer risk.
  • Alison Luk Young
  • Phyllis N Butow
  • Katherine M Tucker
  • Claire E Wakefield
  • Emma Healey
  • Rachel Williams
  • BMJ Open.2020 02;10(2):e033127. bmjopen-2019-033127. doi: 10.1136/bmjopen-2019-033127.Epub 2020-02-25.

重度の白内障はM1中大脳動脈閉塞性脳卒中の再灌流術成功後の不良な転帰と関連している

Severe Leukoaraiosis Is Associated with Poor Outcome after Successful Recanalization of M1 Middle Cerebral Artery Occlusion Strokes.
  • Johannes Sebastian Mutzenbach
  • Erasmia Müller-Thies-Broussalis
  • Monika Killer-Oberpfalzer
  • Christoph Johannes Griessenauer
  • Constantin Hecker
  • Luis Rafael Moscote-Salazar
  • Pia Paradaiser
  • Slaven Pikija
  • Cerebrovasc. Dis..2020 Jun;:1-9. 000508209. doi: 10.1159/000508209.Epub 2020-06-12.

コラーゲンの安定同位体分析によるサケ科魚類の移動生態タイプの鑑別。考古学的・生態学的応用

Differentiating salmonid migratory ecotypes through stable isotope analysis of collagen: Archaeological and ecological applications.
  • Eric Guiry
  • Thomas C A Royle
  • R G Matson
  • Hillary Ward
  • Tyler Weir
  • Nicholas Waber
  • Thomas J Brown
  • Brian P V Hunt
  • Michael H H Price
  • Bruce P Finney
  • Masahide Kaeriyama
  • Yuxue Qin
  • Dongya Y Yang
  • Paul Szpak
  • PLoS ONE.2020;15(4):e0232180. PONE-D-20-03408. doi: 10.1371/journal.pone.0232180.Epub 2020-04-28.

脳卒中後片麻痺患者の下肢筋電図活動に対する生理学的感受性の高い歩行運動の意義.低リソース環境におけるフィージビリティスタディ

Implications of Physiology-Sensitive Gait Exercise on the Lower Limb Electromyographic Activity of Hemiplegic Post-Stroke Patients: A Feasibility Study in Low Resource Settings.
  • Dhaval Solanki
  • Siddhant Kumar
  • B Shubha
  • Uttama Lahiri
  • IEEE J Transl Eng Health Med.2020;8:2100709. 2100709. doi: 10.1109/JTEHM.2020.3006181.Epub 2020-07-01.

成人期のスティル病と乳がんに対する放射線治療。この稀な学会の管理についての症例報告と文献レビュー

Adult Onset Still's Disease and Radiotherapy treatment for breast cancer: Case report about management of this rare association and literature review.
  • Fabio Marazzi
  • Valeria Masiello
  • Gianluca Franceschini
  • Silvia Bosello
  • Francesca Moschella
  • Daniela Smaniotto
  • Stefano Luzi
  • Antonino Mulé
  • Maria Antonietta Gambacorta
  • Elisa Gremese
  • Riccardo Masetti
  • Vincenzo Valentini
  • Rep Pract Oncol Radiother.2020 Jul-Aug;25(4):527-532. S1507-1367(20)30042-0. doi: 10.1016/j.rpor.2020.03.013.Epub 2020-05-22.

COVID-19患者のヘリコプター搬送に関するガイドライン作成のための意思決定支援ツールと提案

Decision support tool and suggestions for the development of guidelines for the helicopter transport of patients with COVID-19.
  • Per P Bredmose
  • Monica Diczbalis
  • Emma Butterfield
  • Karel Habig
  • Andrew Pearce
  • Svein Are Osbakk
  • Ville Voipio
  • Marcus Rudolph
  • Alistair Maddock
  • John O'Neill
  • Scand J Trauma Resusc Emerg Med.2020 May;28(1):43. 10.1186/s13049-020-00736-7. doi: 10.1186/s13049-020-00736-7.Epub 2020-05-25.

韓国でCOVID-19感染症の三次感染を引き起こした指標患者の症例:定量的RT-PCRでモニターしたCOVID-19感染肺炎の治療にロピナビル/リトナビルの適用を検討

Case of the Index Patient Who Caused Tertiary Transmission of COVID-19 Infection in Korea: the Application of Lopinavir/Ritonavir for the Treatment of COVID-19 Infected Pneumonia Monitored by Quantitative RT-PCR.
  • Jaegyun Lim
  • Seunghyun Jeon
  • Hyun Young Shin
  • Moon Jung Kim
  • Yu Min Seong
  • Wang Jun Lee
  • Kang Won Choe
  • Yu Min Kang
  • Baeckseung Lee
  • Sang Joon Park
  • J. Korean Med. Sci..2020 Feb;35(6):e79. 35.e79. doi: 10.3346/jkms.2020.35.e79.Epub 2020-02-17.

術後の急性疼痛管理のためのガバペンチノイドの周術期使用:システマティックレビューとメタアナリシス

Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis.
  • Michael Verret
  • François Lauzier
  • Ryan Zarychanski
  • Caroline Perron
  • Xavier Savard
  • Anne-Marie Pinard
  • Guillaume Leblanc
  • Marie-Joëlle Cossi
  • Xavier Neveu
  • Alexis F Turgeon
  • Anesthesiology.2020 08;133(2):265-279. 00000542-202008000-00011. doi: 10.1097/ALN.0000000000003428.

乳がんの高齢女性における虚弱体質とホルモン療法補助療法のアドヒアランス。CALGBプロトコル369901

Frailty and adherence to adjuvant hormonal therapy in older women with breast cancer: CALGB protocol 369901.
  • Vanessa B Sheppard
  • Leigh Anne Faul
  • George Luta
  • Jonathan D Clapp
  • Rachel L Yung
  • Judy Huei-Yu Wang
  • Gretchen Kimmick
  • Claudine Isaacs
  • Michelle Tallarico
  • William T Barry
  • Brandelyn N Pitcher
  • Clifford Hudis
  • Eric P Winer
  • Harvey J Cohen
  • Hyman B Muss
  • Arti Hurria
  • Jeanne S Mandelblatt
  • J. Clin. Oncol..2014 Aug;32(22):2318-27. JCO.2013.51.7367. doi: 10.1200/JCO.2013.51.7367.Epub 2014-06-16.

ガーナ・クマシの第三次病院における産後女性の尊重的なマタニティケアの経験を測定するためのツールの開発

Developing a tool for measuring postpartum women's experiences of respectful maternity care at a tertiary hospital in Kumasi, Ghana.
  • Veronica Millicent Dzomeku
  • Adwoa Bemah Boamah Mensah
  • Kweku Emmanuel Nakua
  • Pascal Agbadi
  • Jody R Lori
  • Peter Donkor
  • Heliyon.2020 Jul;6(7):e04374. S2405-8440(20)31218-4. doi: 10.1016/j.heliyon.2020.e04374.Epub 2020-07-10.

界面活性剤によりヌクレアーゼへのDNAアクセス性が向上し、淋菌の表現型β-ラクタム系抗生物質感受性試験が加速された

Surfactant-enhanced DNA accessibility to nuclease accelerates phenotypic β-lactam antibiotic susceptibility testing of Neisseria gonorrhoeae.
  • Emily S Savela
  • Nathan G Schoepp
  • Matthew M Cooper
  • Justin C Rolando
  • Jeffrey D Klausner
  • Olusegun O Soge
  • Rustem F Ismagilov
  • PLoS Biol..2020 03;18(3):e3000651. PBIOLOGY-D-19-01871. doi: 10.1371/journal.pbio.3000651.Epub 2020-03-19.

Gluconacetobacter diazotrophicus (Gd6PGD)由来の新規な膜関連6-ホスホグルコン酸デヒドロゲナーゼの構造から、短鎖6PGDのサブファミリーが明らかになった

The structure of a novel membrane-associated 6-phosphogluconate dehydrogenase from Gluconacetobacter diazotrophicus (Gd6PGD) reveals a subfamily of short-chain 6PGDs.
  • Pedro D Sarmiento-Pavía
  • Annia Rodríguez-Hernández
  • Adela Rodríguez-Romero
  • Martha E Sosa-Torres
  • FEBS J..2020 Jul;doi: 10.1111/febs.15472.Epub 2020-07-04.

胃もたれ症の症状を持つ患者における大麻の使用。有病率、患者の特徴、および知覚された有益性

Marijuana Use in Patients with Symptoms of Gastroparesis: Prevalence, Patient Characteristics, and Perceived Benefit.
  • Henry P Parkman
  • Emily P Sharkey
  • Linda A Nguyen
  • Katherine P Yates
  • Thomas L Abell
  • William L Hasler
  • William Snape
  • John Clarke
  • Ron Schey
  • Kenneth L Koch
  • Braden Kuo
  • Richard W McCallum
  • Irene Sarosiek
  • Madhusudan Grover
  • Gianrico Farrugia
  • James Tonascia
  • Pankaj J Pasricha
  • Dig. Dis. Sci..2020 Aug;65(8):2311-2320. 10.1007/s10620-019-05963-2. doi: 10.1007/s10620-019-05963-2.Epub 2019-11-22.

アンドロゲンが媒介する性の偏りは、オスにおけるロイコトリエン生合成阻害剤の効率を損なう

Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males.
  • Simona Pace
  • Carlo Pergola
  • Friederike Dehm
  • Antonietta Rossi
  • Jana Gerstmeier
  • Fabiana Troisi
  • Helmut Pein
  • Anja M Schaible
  • Christina Weinigel
  • Silke Rummler
  • Hinnak Northoff
  • Stefan Laufer
  • Thorsten J Maier
  • Olof Rådmark
  • Bengt Samuelsson
  • Andreas Koeberle
  • Lidia Sautebin
  • Oliver Werz
  • J. Clin. Invest..2017 Aug;127(8):3167-3176. 92885. doi: 10.1172/JCI92885.Epub 2017-07-24.

CDX2導入によるヒトiPSC由来腸管上皮細胞単分子膜の作製

Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction.
  • Kazuo Takayama
  • Ryosuke Negoro
  • Tomoki Yamashita
  • Kanae Kawai
  • Moe Ichikawa
  • Takanori Mori
  • Noriyuki Nakatsu
  • Kazuo Harada
  • Sumito Ito
  • Hiroshi Yamada
  • Yoshiyuki Yamaura
  • Kazumasa Hirata
  • Seiichi Ishida
  • Hiroyuki Mizuguchi
  • Cell Mol Gastroenterol Hepatol.2019;8(3):513-526. S2352-345X(19)30082-7. doi: 10.1016/j.jcmgh.2019.06.004.Epub 2019-06-19.

エプスタイン-バーウイルスエピトープ-主要組織適合性複合体の相互作用と収束的な組み換えが、多様なT細胞受容体αおよびβレパートワイアの選択を促進することを明らかにした

Epstein-Barr Virus Epitope-Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor α and β Repertoires.
  • Anna Gil
  • Larisa Kamga
  • Ramakanth Chirravuri-Venkata
  • Nuray Aslan
  • Fransenio Clark
  • Dario Ghersi
  • Katherine Luzuriaga
  • Liisa K Selin
  • mBio.2020 03;11(2). e00250-20. doi: 10.1128/mBio.00250-20.Epub 2020-03-17.

リゾホスファチジン酸は好中球の細胞外トラップの迅速な形成を誘導して血栓の安定性を促進する。血栓症の新たなメカニズム

Lysophosphatidic acid promotes thrombus stability by inducing rapid formation of neutrophil extracellular traps: A new mechanism of thrombosis.
  • Tiewei Li
  • Rui Peng
  • Fang Wang
  • Lu Hua
  • Sheng Liu
  • Zhiyan Han
  • Jianqiu Pei
  • Shengqiang Pei
  • Zhenwen Zhao
  • Xin Jiang
  • Xi Chen
  • J. Thromb. Haemost..2020 Apr;doi: 10.1111/jth.14839.Epub 2020-04-15.