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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

遺伝的機能障害の根底にある広範な大動脈・頸動脈・腹部解剖を有する患者における欠失の分子的影響の検討

Examination of Molecular Effects of Deletion in a Patient with Extensive Aortic, Carotid, and Abdominal Dissections That Underlie the Genetic Dysfunction.
  • Sarah K Macklin
  • Katelyn A Bruno
  • Charitha Vadlamudi
  • Haytham Helmi
  • Ayesha Samreen
  • Ahmed N Mohammad
  • Stepahnie Hines
  • Paldeep S Atwal
  • Thomas R Caulfield
  • Case Rep Med.2020;2020:5108052. doi: 10.1155/2020/5108052.Epub 2020-06-19.

TLR3および7/8アゴニストベースのDC成熟化カクテルにおけるプロスタグランジンEは、成熟したサイトカイン産生性の遊走性DCを産生するが、CD8 T細胞への抗原クロスプレゼンテーションを損なう

Prostaglandin E in a TLR3- and 7/8-agonist-based DC maturation cocktail generates mature, cytokine-producing, migratory DCs but impairs antigen cross-presentation to CD8 T cells.
  • Philipp Gierlich
  • Veronika Lex
  • Antje Technau
  • Anne Keupp
  • Lorenz Morper
  • Amelie Glunz
  • Hanno Sennholz
  • Johannes Rachor
  • Sascha Sauer
  • Ana Marcu
  • Götz Ulrich Grigoleit
  • Matthias Wölfl
  • Paul G Schlegel
  • Matthias Eyrich
  • Cancer Immunol. Immunother..2020 Jun;69(6):1029-1042. 10.1007/s00262-019-02470-1. doi: 10.1007/s00262-019-02470-1.Epub 2020-02-25.

ドコサヘキサエン酸は、肺動脈平滑筋細胞のmicroRNA-16をアップレギュレートすることでCa流入を抑制し、CaSRをダウンレギュレートする

Docosahexaenoic acid inhibits Ca influx and downregulates CaSR by upregulating microRNA-16 in pulmonary artery smooth muscle cells.
  • Jin-Jun Liu
  • Ming-Ming Tang
  • Ming-Li Zhu
  • Cai-Xia Xie
  • Pin-Fang Kang
  • Xuan Ling
  • Heng Zhang
  • Xiao-Jing Wang
  • Bi Tang
  • J. Biochem. Mol. Toxicol..2020 Jul;:e22573. doi: 10.1002/jbt.22573.Epub 2020-07-13.

スフィンゴシンキナーゼ1/スフィンゴシン1-リン酸塩/スフィンゴシン1-リン酸塩受容体1経路。ゲニポシドによる血管新生抑制の新規ターゲット

Sphingosine kinase 1/sphingosine 1-phosphate/sphingosine 1-phosphate receptor 1 pathway: A novel target of geniposide to inhibit angiogenesis.
  • Minghui Sun
  • Ran Deng
  • Yan Wang
  • Hong Wu
  • Zhengrong Zhang
  • Yanhong Bu
  • Heng Zhang
  • Life Sci..2020 Jun;256:117988. S0024-3205(20)30738-4. doi: 10.1016/j.lfs.2020.117988.Epub 2020-06-20.

全身性疾患の歯周病症状と発生・後天性疾患。2017年歯周病およびインプラント周囲疾患・状態の分類に関する世界ワークショップのワークグループ3のコンセンサス報告書

Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.
  • Søren Jepsen
  • Jack G Caton
  • Jasim M Albandar
  • Nabil F Bissada
  • Philippe Bouchard
  • Pierpaolo Cortellini
  • Korkud Demirel
  • Massimo de Sanctis
  • Carlo Ercoli
  • Jingyuan Fan
  • Nicolaas C Geurs
  • Francis J Hughes
  • Lijian Jin
  • Alpdogan Kantarci
  • Evanthia Lalla
  • Phoebus N Madianos
  • Debora Matthews
  • Michael K McGuire
  • Michael P Mills
  • Philip M Preshaw
  • Mark A Reynolds
  • Anton Sculean
  • Cristiano Susin
  • Nicola X West
  • Kazuhisa Yamazaki
  • J. Periodontol..2018 06;89 Suppl 1:S237-S248. doi: 10.1002/JPER.17-0733.

プロトポルフィリンIX上で図示された、非指数的遅延蛍光および燐光減衰分析のための一般的なフレームワーク

A general framework for non-exponential delayed fluorescence and phosphorescence decay analysis, illustrated on Protoporphyrin IX.
  • Gauthier Croizat
  • Aurélien Gregor
  • Emmanuel Gerelli
  • Jaroslava Joniova
  • Marek Scholz
  • Georges Wagnières
  • J. Photochem. Photobiol. B, Biol..2020 Apr;209:111887. S1011-1344(20)30336-5. doi: 10.1016/j.jphotobiol.2020.111887.Epub 2020-04-30.

マルチエコーを用いた拡散強調MRIにおける感度と信号対雑音比の向上

Increased Sensitivity and Signal-to-Noise Ratio in Diffusion-Weighted MRI using Multi-Echo Acquisitions.
  • Cornelius Eichner
  • Michael Paquette
  • Toralf Mildner
  • Torsten Schlumm
  • Kamilla Pleh
  • Liran Samuni
  • Catherine Crockford
  • Roman M Wittig
  • Carsten Jäger
  • Harald E Möller
  • Angela D Friederici
  • Alfred Anwander
  • Neuroimage.2020 Jul;:117172. S1053-8119(20)30658-3. doi: 10.1016/j.neuroimage.2020.117172.Epub 2020-07-15.

溶解性と腸管透過性を改善するためのマイクロエマルジョン中の未熟オリーブ(L. )からのフェノールリッチ抽出物の製剤化

Formulation of a Phenol-Rich Extract from Unripe Olives ( L.) in Microemulsion to Improve Its Solubility and Intestinal Permeability.
  • Lorenzo Cecchi
  • Vieri Piazzini
  • Mario D'Ambrosio
  • Cristina Luceri
  • Federica Rocco
  • Marzia Innocenti
  • Giulia Vanti
  • Nadia Mulinacci
  • Maria Camilla Bergonzi
  • Molecules.2020 Jul;25(14). E3198. doi: 10.3390/molecules25143198.Epub 2020-07-13.

半閉鎖された亜熱帯の湾内で、環境DNA検出の追跡により、ブラックチップ・シャーク(Carcharhinus limbatus)の季節的な発生が確認された

Environmental DNA detection tracks established seasonal occurrence of blacktip sharks (Carcharhinus limbatus) in a semi-enclosed subtropical bay.
  • Bautisse D Postaire
  • Judith Bakker
  • Jayne Gardiner
  • Tonya R Wiley
  • Demian D Chapman
  • Sci Rep.2020 Jul;10(1):11847. 10.1038/s41598-020-68843-0. doi: 10.1038/s41598-020-68843-0.Epub 2020-07-16.

Nulliparous 思春期の青年および若い女性におけるレボノルゲストレル放出型子宮内装置挿入の12時間前の膣ディノプロストンの自己投与の利点。無作為化対照試験

Benefits of Self-administered Vaginal Dinoprostone 12 Hours before Levonorgestrel-releasing Intrauterine Device Insertion in Nulliparous Adolescents and Young Women: A Randomized Controlled Trial.
  • Ahmed Samy
  • Ahmed Said Ali
  • Dina Latif
  • Fatma Faisal Darweesh
  • Nevein Kamal Ghamry
  • Ahmed A Metwally
  • J Pediatr Adolesc Gynecol.2020 Feb;S1083-3188(20)30163-7. doi: 10.1016/j.jpag.2020.02.010.Epub 2020-02-28.

退役軍人健康管理局(Veterans Health Administration)で前立腺がんと診断された患者の平均余命推定値

Life expectancy estimates for patients diagnosed with prostate cancer in the Veterans Health Administration.
  • Ericka M Sohlberg
  • I-Chun Thomas
  • Jaden Yang
  • Kristopher Kapphahn
  • Timothy J Daskivich
  • Ted A Skolarus
  • Jeremy B Shelton
  • Danil V Makarov
  • Jonathan Bergman
  • Christine Ko Bang
  • Mary K Goldstein
  • Todd H Wagner
  • James D Brooks
  • Manisha Desai
  • John T Leppert
  • Urol. Oncol..2020 Jul;S1078-1439(20)30219-2. doi: 10.1016/j.urolonc.2020.05.015.Epub 2020-07-13.

慢性疾患における注射剤治療の提供と管理における促進要因と障壁に関する統合的レビュー。ACNAPプロジェクト「心血管疾患患者における注射薬」の一部

An integrative review on facilitators and barriers in delivering and managing injectable therapies in chronic conditions: A part of the ACNAP project 'injectable medicines among patients with cardiovascular conditions'.
  • Ekaterini Lambrinou
  • Martha Kyriakou
  • Ioanna Lakatamitou
  • Neil Angus
  • Rani Khatib
  • Ercole Vellone
  • Abigail Barrowcliff
  • Tina Birgitte Hansen
  • Geraldine A Lee
  • Eur J Cardiovasc Nurs.2020 Jul;:1474515120939007. doi: 10.1177/1474515120939007.Epub 2020-07-16.

ヒトの新生児のエタノール臭に対する呼吸と感情の反応性は、妊娠中の母親の飲酒パターンに依存している

Respiratory and emotional reactivity to ethanol odor in human neonates is dependent upon maternal drinking patterns during pregnancy.
  • Florencia Anunziata
  • Ana Fabiola Macchione
  • Adriana Sofía Mitrano
  • Génesis D'aloisio
  • Mirta Elena Ferreyra
  • Ricardo David Pontoriero
  • Luis Alberto Ahumada
  • Juan Carlos Molina
  • Drug Alcohol Depend.2020 Jun;213:108100. S0376-8716(20)30265-9. doi: 10.1016/j.drugalcdep.2020.108100.Epub 2020-06-11.

Bowman-Birk阻害剤とその由来ペプチドの血圧低下効果

Blood pressure-lowering effects of a Bowman-Birk inhibitor and its derived peptides in normotensive and hypertensive rats.
  • Maria Alzira Garcia de Freitas
  • Nathalia Oda Amaral
  • Alice da Cunha Morales Álvares
  • Sandriele Aires de Oliveira
  • Azadeh Mehdad
  • Diego Elias Honda
  • Amanda Sá Martins Bessa
  • Marcelo Henrique Soller Ramada
  • Lara Marques Naves
  • Carolina Nobre Ribeiro Pontes
  • Carlos Henrique Castro
  • Gustavo Rodrigues Pedrino
  • Sonia Maria de Freitas
  • Sci Rep.2020 Jul;10(1):11680. 10.1038/s41598-020-66624-3. doi: 10.1038/s41598-020-66624-3.Epub 2020-07-15.

早期生活環境曝露と小児肥満。エクスポゾンワイドアプローチ

Early-Life Environmental Exposures and Childhood Obesity: An Exposome-Wide Approach.
  • Martine Vrijheid
  • Serena Fossati
  • Léa Maitre
  • Sandra Márquez
  • Theano Roumeliotaki
  • Lydiane Agier
  • Sandra Andrusaityte
  • Solène Cadiou
  • Maribel Casas
  • Montserrat de Castro
  • Audrius Dedele
  • David Donaire-Gonzalez
  • Regina Grazuleviciene
  • Line S Haug
  • Rosemary McEachan
  • Helle Margrete Meltzer
  • Eleni Papadopouplou
  • Oliver Robinson
  • Amrit K Sakhi
  • Valerie Siroux
  • Jordi Sunyer
  • Per E Schwarze
  • Ibon Tamayo-Uria
  • Jose Urquiza
  • Marina Vafeiadi
  • Antonia Valentin
  • Charline Warembourg
  • John Wright
  • Mark J Nieuwenhuijsen
  • Cathrine Thomsen
  • Xavier Basagaña
  • Rémy Slama
  • Leda Chatzi
  • Environ. Health Perspect..2020 Jun;128(6):67009. doi: 10.1289/EHP5975.Epub 2020-06-24.

色素上皮由来の新規ナチュラルキラー細胞由来因子である色素上皮由来因子は、妊娠初期に抗炎症と抗アポトーシスを介して間質細胞を保護する

Pigment epithelium-derived factor, a novel decidual natural killer cells-derived factor, protects decidual stromal cells via anti-inflammation and anti-apoptosis in early pregnancy.
  • Ji Zheng
  • Yanhong Li
  • Yifei Sang
  • Ling Xu
  • Xueling Jin
  • Yu Tao
  • Dajin Li
  • Meirong Du
  • Hum. Reprod..2020 Jul;35(7):1537-1552. 5858162. doi: 10.1093/humrep/deaa118.

EPSTI1の上昇は、原発性シェーグレン症候群患者においてNF-κBシグナルを介してB細胞の過剰活性化を促進する

Elevated EPSTI1 promote B cell hyperactivation through NF-κB signalling in patients with primary Sjögren's syndrome.
  • Jin-Lei Sun
  • Hao-Ze Zhang
  • Su-Ying Liu
  • Chao-Feng Lian
  • Zhi-Lei Chen
  • Ti-Hong Shao
  • Shuo Zhang
  • Li-Ling Zhao
  • Cheng-Mei He
  • Mu Wang
  • Wen Zhang
  • Hua Chen
  • Feng-Chun Zhang
  • Ann. Rheum. Dis..2020 04;79(4):518-524. annrheumdis-2019-216428. doi: 10.1136/annrheumdis-2019-216428.Epub 2020-02-29.

甲状腺ホルモン受容体によるtRNAメチルトランスフェラーゼ様1(Mettl1)遺伝子の直接的な活性化は、成体の腸管幹細胞の発生と変態期の増殖に関与していることを示唆している

Direct activation of tRNA methyltransferase-like 1 (Mettl1) gene by thyroid hormone receptor implicates a role in adult intestinal stem cell development and proliferation during metamorphosis.
  • Wonho Na
  • Liezhen Fu
  • Nga Luu
  • Yun-Bo Shi
  • Cell Biosci.2020;10:60. 423. doi: 10.1186/s13578-020-00423-1.Epub 2020-05-04.

カスパーゼ11はアレルギー性気道炎症を促進する

Caspase-11 promotes allergic airway inflammation.
  • Zbigniew Zasłona
  • Ewelina Flis
  • Mieszko M Wilk
  • Richard G Carroll
  • Eva M Palsson-McDermott
  • Mark M Hughes
  • Ciana Diskin
  • Kathy Banahan
  • Dylan G Ryan
  • Alexander Hooftman
  • Alicja Misiak
  • Jay Kearney
  • Gunter Lochnit
  • Wilhelm Bertrams
  • Timm Greulich
  • Bernd Schmeck
  • Oliver J McElvaney
  • Kingston H G Mills
  • Ed C Lavelle
  • Małgorzata Wygrecka
  • Emma M Creagh
  • Luke A J O'Neill
  • Nat Commun.2020 02;11(1):1055. 10.1038/s41467-020-14945-2. doi: 10.1038/s41467-020-14945-2.Epub 2020-02-26.

外傷を受けた上顎中切歯の治療と審美的管理に歯内療法とインサイド/アウトサイドブリーチング法を用いた.臨床報告

Treatment and esthetic management of traumatized maxillary central incisors with endodontic therapy and the inside/outside bleaching technique: A clinical report.
  • Michael L Myers
  • Mario F Romero
  • Lisiane F Susin
  • Courtney S Babb
  • J Prosthet Dent.2019 Oct;122(4):343-347. S0022-3913(18)31019-9. doi: 10.1016/j.prosdent.2018.10.020.Epub 2019-04-23.

心血管リスク因子は脳卒中重症度と先行認知機能障害を介して脳卒中後の急性認知に間接的に影響を与える:モデレートされた媒介分析

Cardiovascular risk factors indirectly affect acute post-stroke cognition through stroke severity and prior cognitive impairment: a moderated mediation analysis.
  • Bogna A Drozdowska
  • Emma Elliott
  • Martin Taylor-Rowan
  • Robert C Shaw
  • Gillian Cuthbertson
  • Peter Langhorne
  • Terence J Quinn
  • Alzheimers Res Ther.2020 Jul;12(1):85. 10.1186/s13195-020-00653-y. doi: 10.1186/s13195-020-00653-y.Epub 2020-07-16.

式:text参照、黒人参由来の希少なプロトパナキサトリオール型ジンセノサイド画分、Suppresses Inflammatory Gene iNOS via the Iinhibition of p-STAT-1 and NF-Formula:textB

[Formula: see text], a Rare Protopanaxatriol-Type Ginsenoside Fraction from Black Ginseng, Suppresses Inflammatory Gene iNOS via the Iinhibition of p-STAT-1 and NF-[Formula: see text]B.
  • So Yeon Jeong
  • Ji-Eun Kim
  • Gyu-Yong Song
  • Jong-Sup Bae
  • Am. J. Chin. Med..2020;48(5):1091-1102. doi: 10.1142/S0192415X20500536.

肝臓科プロバイダーのトレーニングは、アルコール使用障害のスクリーニングとその結果としての介入を改善する

Training of hepatology providers improves the screening and resultant interventions for alcohol use disorder.
  • Hamzeh Saraireh
  • Joseph Redman
  • Thaer Abdelfattah
  • Sasha Mangray
  • James B Wade
  • HoChong S Gilles
  • Michael Fuchs
  • April Morris
  • Zenaida Malpaya
  • Puneet Puri
  • Brian C Davis
  • Samarth S Patel
  • Jasmohan S Bajaj
  • Liver Int..2020 Jul;doi: 10.1111/liv.14589.Epub 2020-07-07.

PD-L1発現率≧50%のNSCLC患者の大規模実世界コホートにおけるペムブロリズマブの免疫関連有害事象と臨床成績との関係

Immune-related Adverse Events of Pembrolizumab in a Large Real-world Cohort of Patients With NSCLC With a PD-L1 Expression ≥ 50% and Their Relationship With Clinical Outcomes.
  • Alessio Cortellini
  • Alex Friedlaender
  • Giuseppe L Banna
  • Giampiero Porzio
  • Melissa Bersanelli
  • Federico Cappuzzo
  • Joachim G J V Aerts
  • Raffaele Giusti
  • Emilio Bria
  • Diego Cortinovis
  • Francesco Grossi
  • Maria R Migliorino
  • Domenico Galetta
  • Francesco Passiglia
  • Rossana Berardi
  • Francesca Mazzoni
  • Vincenzo Di Noia
  • Diego Signorelli
  • Alessandro Tuzi
  • Alain Gelibter
  • Paolo Marchetti
  • Marianna Macerelli
  • Francesca Rastelli
  • Rita Chiari
  • Danilo Rocco
  • Alessandro Inno
  • Pietro Di Marino
  • Giovanni Mansueto
  • Federica Zoratto
  • Matteo Santoni
  • Marianna Tudini
  • Michele Ghidini
  • Marco Filetti
  • Annamaria Catino
  • Pamela Pizzutilo
  • Luca Sala
  • Mario Alberto Occhipinti
  • Fabrizio Citarella
  • Russano Marco
  • Mariangela Torniai
  • Luca Cantini
  • Alessandro Follador
  • Vincenzo Sforza
  • Olga Nigro
  • Miriam G Ferrara
  • Ettore D'Argento
  • Alessandro Leonetti
  • Linda Pettoruti
  • Lorenzo Antonuzzo
  • Simona Scodes
  • Lorenza Landi
  • Giorgia Guaitoli
  • Cinzia Baldessari
  • Federica Bertolini
  • Luigi Della Gravara
  • Maria Giovanna Dal Bello
  • Robert A Belderbos
  • Marco De Filippis
  • Cristina Cecchi
  • Serena Ricciardi
  • Clelia Donisi
  • Alessandro De Toma
  • Claudia Proto
  • Alfredo Addeo
  • Ornella Cantale
  • Biagio Ricciuti
  • Carlo Genova
  • Alessandro Morabito
  • Daniele Santini
  • Corrado Ficorella
  • Katia Cannita
  • Clin Lung Cancer.2020 Jun;S1525-7304(20)30204-7. doi: 10.1016/j.cllc.2020.06.010.Epub 2020-06-21.

フラクトース含有糖類の主要な食品供給源と罹患メタボリックシンドロームとの関連。システマティックレビューとメタアナリシス

Association of Major Food Sources of Fructose-Containing Sugars With Incident Metabolic Syndrome: A Systematic Review and Meta-analysis.
  • Zhila Semnani-Azad
  • Tauseef A Khan
  • Sonia Blanco Mejia
  • Russell J de Souza
  • Lawrence A Leiter
  • Cyril W C Kendall
  • Anthony J Hanley
  • John L Sievenpiper
  • JAMA Netw Open.2020 Jul;3(7):e209993. 2768092. doi: 10.1001/jamanetworkopen.2020.9993.Epub 2020-07-01.

一酸化窒素/cGMPシグナル伝達経路とカリウムチャネルがノトファギンの血圧降下作用に寄与していることを明らかにした

Nitric oxide/cGMP signaling pathway and potassium channels contribute to hypotensive effects of nothofagin.
  • Claudio H da Silva
  • Rhanany A Palozi
  • Priscila de Souza
  • Camila L de Almeida
  • Valdir Cechinel-Filho
  • Emerson L Lourenço
  • Arquimedes Gasparotto Junior
  • Minerva Cardioangiol.2020 Jul;S0026-4725.20.05243-3. doi: 10.23736/S0026-4725.20.05243-3.Epub 2020-07-10.

高リスク神経芽腫I-mIBG治療症例におけるより個別化医療のためのバイオドシメトリーツールとしての二心染色体アッセイの評価

Assessment of the dicentric chromosome assay as a biodosimetry tool for more personalized medicine in a case of a high risk neuroblastoma I-mIBG treatment.
  • Jose Maria Chimeno
  • Natividad Sebastià
  • Irene Torres-Espallardo
  • Julia Balaguer
  • Cristian Candela-Juan
  • Jose Luis Loaiza
  • Mar Adria
  • Blanca Ibanez-Rosello
  • Adela Cañete
  • Luis Martí-Bonmatí
  • Alegría Montoro
  • Int. J. Radiat. Biol..2019 03;95(3):314-320. doi: 10.1080/09553002.2019.1549755.Epub 2019-01-11.