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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

潜在的なフレーバー培養物。Lactobacillus harbinensis M1は、2,3-ブタンジオンとアセトインの高産生により、発酵豆乳のオルガノレプティックな品質を向上させる

A potential flavor culture: Lactobacillus harbinensis M1 improves the organoleptic quality of fermented soymilk by high production of 2,3-butanedione and acetoin.
  • Yin Zheng
  • Yongtao Fei
  • Yue Yang
  • Zekun Jin
  • Baoning Yu
  • Li Li
  • Food Microbiol..2020 Oct;91:103540. S0740-0020(20)30129-5. doi: 10.1016/j.fm.2020.103540.Epub 2020-05-03.

個別化された治療予測は、無作為化試験において、集団平均的なアプローチと比較して転帰を改善することができるか?大うつ病の急性期治療の実用的メガトリアールにおける多変量予測モデルの開発と検証

Can personalized treatment prediction improve the outcomes, compared with the group average approach, in a randomized trial? Developing and validating a multivariable prediction model in a pragmatic megatrial of acute treatment for major depression.
  • Toshi A Furukawa
  • Thomas P A Debray
  • Tatsuo Akechi
  • Mitsuhiko Yamada
  • Tadashi Kato
  • Michael Seo
  • Orestis Efthimiou
  • J Affect Disord.2020 Sep;274:690-697. S0165-0327(20)30097-5. doi: 10.1016/j.jad.2020.05.141.Epub 2020-05-30.

ナノメディシンと脂質ベースの薬物送達システムにおける残留溶媒:プロセスをよりよく理解するためのケーススタディ

Residual Solvents in Nanomedicine and Lipid-Based Drug Delivery Systems: a Case Study to Better Understand Processes.
  • Amrita Dikpati
  • Farzad Mohammadi
  • Karine Greffard
  • Caroline Quéant
  • Philippe Arnaud
  • Guillaume Bastiat
  • Iwona Rudkowska
  • Nicolas Bertrand
  • Pharm. Res..2020 Jul;37(8):149. 10.1007/s11095-020-02877-x. doi: 10.1007/s11095-020-02877-x.Epub 2020-07-17.

イブプロフェンではなくメタミゾールはセルトラリンの血漿中濃度を低下させる - 疼痛とうつ病・不安障害の同時治療への示唆

Metamizole but not Ibuprofen reduces the plasma concentration of sertraline - Implications for the concurrent treatment of pain and depression/anxiety disorders.
  • Arnim Johannes Gaebler
  • Georgios Schoretsanitis
  • Nagia Ben Omar
  • Ekkehard Haen
  • Katharina Endres
  • Christoph Hiemke
  • Michael Paulzen
  • Br J Clin Pharmacol.2020 Jul;doi: 10.1111/bcp.14471.Epub 2020-07-11.

メトホルミンの同定と妥当性の検証 トール様受容体経路を標的とすることでPM誘発マクロファージの細胞毒性を防御する

Identification and validation of metformin protects against PM-induced macrophages cytotoxicity by targeting toll like receptor pathway.
  • Yanfeng Shi
  • Josevata Werelagi Batibawa
  • Modibo Maiga
  • Baiyang Sun
  • Yang Li
  • Junchao Duan
  • Zhiwei Sun
  • Chemosphere.2020 Jul;251:126526. S0045-6535(20)30719-0. doi: 10.1016/j.chemosphere.2020.126526.Epub 2020-03-27.

高リスクの難治性神経芽腫に対するI-metaiodobenzylguanidine(I-mIBG)とtopotecanによる線量評価に基づく高活性療法

Dosimetry-based high-activity therapy with I-metaiodobenzylguanidine (I-mIBG) and topotecan for the treatment of high-risk refractory neuroblastoma.
  • Jose Genolla
  • Trinidad Rodriguez
  • Pablo Minguez
  • Ricardo Lopez-Almaraz
  • Veronica Llorens
  • Aizpea Echebarria
  • Eur. J. Nucl. Med. Mol. Imaging.2019 Jul;46(7):1567-1575. 10.1007/s00259-019-04291-x. doi: 10.1007/s00259-019-04291-x.Epub 2019-03-05.

シンバスタチン負荷高分子ミセルは、進行性慢性肝疾患の前臨床モデルにおいて、従来のスタチンよりも有効性が高く、毒性が低いことが示された

Simvastatin-loaded polymeric micelles are more effective and less toxic than conventional statins in a pre-clinical model of advanced chronic liver disease.
  • Diana Hide
  • Mar Gil
  • Fernanda Andrade
  • Diana Rafael
  • Imma Raurell
  • Miren Bravo
  • Aurora Barberá
  • Jordi Gracia-Sancho
  • Víctor Vargas
  • Salvador Augustin
  • Joan Genescà
  • Simo Schwartz
  • Maria Martell
  • Nanomedicine.2020 Jul;:102267. S1549-9634(20)30121-0. doi: 10.1016/j.nano.2020.102267.Epub 2020-07-15.

多糖類を豊富に含むヒドロゲル製剤と光生物学的調節を組み合わせることで、マウスの皮膚における紫外線誘発性光損傷を修復します

Polysaccharide-rich hydrogel formulation combined with photobiomodulation repairs UV-induced photodamage in mice skin.
  • Lia Mara Grosso Neves
  • Nivaldo Antonio Parizotto
  • Carla Roberta Tim
  • Elaine Medeiros Floriano
  • Renata F Vianna Lopez
  • Tiago Venâncio
  • João Batista Fernandes
  • Marcia Regina Cominetti
  • Wound Repair Regen.2020 Jun;doi: 10.1111/wrr.12826.Epub 2020-06-26.

スイカにおけるキュウリグリーンモットルモザイクウイルス感染に対応した長鎖ノンコーディングRNAと環状RNAのゲノムワイドな同定により、ceRNAネットワークが明らかになった

Genome-wide identification of long non-coding RNAs and circular RNAs reveal their ceRNA networks in response to cucumber green mottle mosaic virus infection in watermelon.
  • Yuyan Sun
  • Huiqing Zhang
  • Min Fan
  • Yanjun He
  • Pingan Guo
  • Arch. Virol..2020 May;165(5):1177-1190. 10.1007/s00705-020-04589-4. doi: 10.1007/s00705-020-04589-4.Epub 2020-03-30.

COVID-19パンデミック初期における泌尿器科における外科的・腫瘍学的臨床実践の世界的変化

Global change of surgical and oncological clinical practice in urology during early COVID-19 pandemic.
  • Robert Dotzauer
  • Katharina Böhm
  • Maximilian Peter Brandt
  • Peter Sparwasser
  • Maximilian Haack
  • Sebastian Karl Frees
  • Mohamed Mostafa Kamal
  • René Mager
  • Wolfgang Jäger
  • Thomas Höfner
  • Igor Tsaur
  • Axel Haferkamp
  • Hendrik Borgmann
  • World J Urol.2020 Jul;10.1007/s00345-020-03333-6. doi: 10.1007/s00345-020-03333-6.Epub 2020-07-04.

院内感染性とフルオロキノロン系抗菌薬,テトラサイクリン系抗菌薬,トリメトプリム-スルファメトキサゾール系抗菌薬への感受性が明らかになった

Comparative genomics and antimicrobial resistance profiling of isolates reveals nosocomial transmission and susceptibility to fluoroquinolones, tetracyclines and trimethoprim-sulfamethoxazole.
  • Delaney Burnard
  • Letitia Gore
  • Andrew Henderson
  • Ama Ranasinghe
  • Haakon Bergh
  • Kyra Cottrell
  • Derek S Sarovich
  • Erin P Price
  • David L Paterson
  • Patrick N A Harris
  • J. Clin. Microbiol..2020 Jun;JCM.00730-20. doi: 10.1128/JCM.00730-20.Epub 2020-06-24.

出版社の訂正。発達段階に特異的な分布とMblk-1、ミツバチの脳内でのエクシステロイドシグナル伝達に関与する転写因子のリン酸化

Publisher Correction: Developmental stage-specific distribution and phosphorylation of Mblk-1, a transcription factor involved in ecdysteroid-signaling in the honey bee brain.
  • Hitomi Kumagai
  • Takekazu Kunieda
  • Korefumi Nakamura
  • Yasuhiro Matsumura
  • Manami Namiki
  • Hiroki Kohno
  • Takeo Kubo
  • Sci Rep.2020 Jul;10(1):11577. 10.1038/s41598-020-68540-y. doi: 10.1038/s41598-020-68540-y.Epub 2020-07-09.

ユーラシアの大草原を越えた137の古代ヒトゲノム

137 ancient human genomes from across the Eurasian steppes.
  • Peter de Barros Damgaard
  • Nina Marchi
  • Simon Rasmussen
  • Michaël Peyrot
  • Gabriel Renaud
  • Thorfinn Korneliussen
  • J Víctor Moreno-Mayar
  • Mikkel Winther Pedersen
  • Amy Goldberg
  • Emma Usmanova
  • Nurbol Baimukhanov
  • Valeriy Loman
  • Lotte Hedeager
  • Anders Gorm Pedersen
  • Kasper Nielsen
  • Gennady Afanasiev
  • Kunbolot Akmatov
  • Almaz Aldashev
  • Ashyk Alpaslan
  • Gabit Baimbetov
  • Vladimir I Bazaliiskii
  • Arman Beisenov
  • Bazartseren Boldbaatar
  • Bazartseren Boldgiv
  • Choduraa Dorzhu
  • Sturla Ellingvag
  • Diimaajav Erdenebaatar
  • Rana Dajani
  • Evgeniy Dmitriev
  • Valeriy Evdokimov
  • Karin M Frei
  • Andrey Gromov
  • Alexander Goryachev
  • Hakon Hakonarson
  • Tatyana Hegay
  • Zaruhi Khachatryan
  • Ruslan Khaskhanov
  • Egor Kitov
  • Alina Kolbina
  • Tabaldiev Kubatbek
  • Alexey Kukushkin
  • Igor Kukushkin
  • Nina Lau
  • Ashot Margaryan
  • Inga Merkyte
  • Ilya V Mertz
  • Viktor K Mertz
  • Enkhbayar Mijiddorj
  • Vyacheslav Moiyesev
  • Gulmira Mukhtarova
  • Bekmukhanbet Nurmukhanbetov
  • Z Orozbekova
  • Irina Panyushkina
  • Karol Pieta
  • Václav Smrčka
  • Irina Shevnina
  • Andrey Logvin
  • Karl-Göran Sjögren
  • Tereza Štolcová
  • Angela M Taravella
  • Kadicha Tashbaeva
  • Alexander Tkachev
  • Turaly Tulegenov
  • Dmitriy Voyakin
  • Levon Yepiskoposyan
  • Sainbileg Undrakhbold
  • Victor Varfolomeev
  • Andrzej Weber
  • Melissa A Wilson Sayres
  • Nikolay Kradin
  • Morten E Allentoft
  • Ludovic Orlando
  • Rasmus Nielsen
  • Martin Sikora
  • Evelyne Heyer
  • Kristian Kristiansen
  • Eske Willerslev
  • Nature.2018 05;557(7705):369-374. 10.1038/s41586-018-0094-2. doi: 10.1038/s41586-018-0094-2.Epub 2018-05-09.

複製適合性小胞性口内炎ウイルスワクチンベクターは SARS-CoV-2 が媒介する病原体から保護します

Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis.
  • James Brett Case
  • Paul W Rothlauf
  • Rita E Chen
  • Natasha M Kafai
  • Julie M Fox
  • Swathi Shrihari
  • Broc T McCune
  • Ian B Harvey
  • Brittany Smith
  • Shamus P Keeler
  • Louis-Marie Bloyet
  • Emma S Winkler
  • Michael J Holtzman
  • Daved H Fremont
  • Sean P J Whelan
  • Michael S Diamond
  • bioRxiv.2020 Jul;2020.07.09.196386. doi: 10.1101/2020.07.09.196386.Epub 2020-07-10.

原発運動野および皮質脊髄路の近くに位置する高悪性度グリオーマの放射線治療計画へのBOLD-fMRIおよびDTIの統合

Integration of BOLD-fMRI and DTI into radiation treatment planning for high-grade gliomas located near the primary motor cortexes and corticospinal tracts.
  • Minglei Wang
  • Hui Ma
  • Xiaodong Wang
  • Yanhong Guo
  • Xinshe Xia
  • Hechun Xia
  • Yulin Guo
  • Xueying Huang
  • Hong He
  • Xiaoxiong Jia
  • Yan Xie
  • Radiat Oncol.2015 Mar;10:64. 10.1186/s13014-015-0364-1. doi: 10.1186/s13014-015-0364-1.Epub 2015-03-08.

ラ・クロースウイルスポリメラーゼの完全長ポリメラーゼの開始前構造と伸長構造から、機能的に重要な構造変化が明らかになった

Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
  • Benoît Arragain
  • Grégory Effantin
  • Piotr Gerlach
  • Juan Reguera
  • Guy Schoehn
  • Stephen Cusack
  • Hélène Malet
  • Nat Commun.2020 Jul;11(1):3590. 10.1038/s41467-020-17349-4. doi: 10.1038/s41467-020-17349-4.Epub 2020-07-17.

また、p62/SQSTM1 の分解阻害と転写活性化による蓄積は、NF-κB 活性化を介したシリカナノ粒子誘起気道炎症に重要な役割を果たしていることが示唆された

p62/SQSTM1 accumulation due to degradation inhibition and transcriptional activation plays a critical role in silica nanoparticle-induced airway inflammation via NF-κB activation.
  • Yifan Wu
  • Yang Jin
  • Tianyu Sun
  • Piaoyu Zhu
  • Jinlong Li
  • Qinglin Zhang
  • Xiaoke Wang
  • Junkang Jiang
  • Gang Chen
  • Xinyuan Zhao
  • J Nanobiotechnology.2020 May;18(1):77. 10.1186/s12951-020-00634-1. doi: 10.1186/s12951-020-00634-1.Epub 2020-05-19.

エチオピアにおけるPlasmodium vivax Duffy Binding Proteinの頻発とその疫学的意義

Frequent expansion of Plasmodium vivax Duffy Binding Protein in Ethiopia and its epidemiological significance.
  • Eugenia Lo
  • Jessica B Hostetler
  • Delenasaw Yewhalaw
  • Richard D Pearson
  • Muzamil M A Hamid
  • Karthigayan Gunalan
  • Daniel Kepple
  • Anthony Ford
  • Daniel A Janies
  • Julian C Rayner
  • Louis H Miller
  • Guiyun Yan
  • PLoS Negl Trop Dis.2019 09;13(9):e0007222. PNTD-D-19-00177. doi: 10.1371/journal.pntd.0007222.Epub 2019-09-11.

血液由来樹状細胞ワクチン接種は、化学療法を受けていない去勢抵抗性前立腺癌患者の臨床転帰と相関する免疫応答を誘導する

Blood-derived dendritic cell vaccinations induce immune responses that correlate with clinical outcome in patients with chemo-naive castration-resistant prostate cancer.
  • Harm Westdorp
  • Jeroen H A Creemers
  • Inge M van Oort
  • Gerty Schreibelt
  • Mark A J Gorris
  • Niven Mehra
  • Michiel Simons
  • Anna L de Goede
  • Michelle M van Rossum
  • Alexandra J Croockewit
  • Carl G Figdor
  • J Alfred Witjes
  • Erik H J G Aarntzen
  • Roel D M Mus
  • Mareke Brüning
  • Katja Petry
  • Martin Gotthardt
  • Jelle O Barentsz
  • I Jolanda M de Vries
  • Winald R Gerritsen
  • J Immunother Cancer.2019 11;7(1):302. 10.1186/s40425-019-0787-6. doi: 10.1186/s40425-019-0787-6.Epub 2019-11-14.

妊娠におけるリンパ球の機能的意義と不妊治療におけるリンパ球免疫療法。包括的なレビューとアップデート

Functional significance of lymphocytes in pregnancy and lymphocyte immunotherapy in infertility: A comprehensive review and update.
  • Roghayeh Jafarpour
  • Salar Pashangzadeh
  • Saber Mehdizadeh
  • Hashem Bayatipoor
  • Zeinab Shojaei
  • Morteza Motallebnezhad
  • Int. Immunopharmacol..2020 Jul;87:106776. S1567-5769(20)31601-5. doi: 10.1016/j.intimp.2020.106776.Epub 2020-07-15.

MEESSI-AHFリスクスコアの性能によるインデックス後の複数のイベントと退院後の短期転帰の予測

MEESSI-AHF risk score performance to predict multiple post-index event and post-discharge short-term outcomes.
  • Xavier Rossello
  • Héctor Bueno
  • Víctor Gil
  • Javier Jacob
  • Francisco Javier Martín-Sánchez
  • Pere Llorens
  • Pablo Herrero Puente
  • Aitor Alquézar-Arbé
  • Sergio Raposeiras-Roubín
  • M Pilar López-Díez
  • Stuart Pocock
  • Òscar Miró
  • Eur Heart J Acute Cardiovasc Care.2020 Jul;:2048872620934318. doi: 10.1177/2048872620934318.Epub 2020-07-17.

転移性乳癌患者における循環腫瘍細胞のアンドロゲン受容体の状態の決定

Determination of the androgen receptor status of circulating tumour cells in metastatic breast cancer patients.
  • Natalia Krawczyk
  • Melissa Neubacher
  • Franziska Meier-Stiegen
  • Hans Neubauer
  • Dieter Niederacher
  • Eugen Ruckhäberle
  • Svjetlana Mohrmann
  • Jürgen Hoffmann
  • Thomas Kaleta
  • Malgorzata Banys-Paluchowski
  • Petra Reinecke
  • Irene Esposito
  • Wolfgang Janni
  • Tanja Fehm
  • BMC Cancer.2019 Nov;19(1):1101. 10.1186/s12885-019-6323-8. doi: 10.1186/s12885-019-6323-8.Epub 2019-11-12.

脳血管急性障害で母体が死亡した場合の周産期転帰:日本における全国調査

Perinatal outcome in case of maternal death for cerebrovascular acute disorders: a nationwide study in Japan.
  • Shinji Katsuragi
  • Hiroaki Tanaka
  • Junichi Hasegawa
  • Akiko Kurasaki
  • Masamitsu Nakamura
  • Naohiro Kanayama
  • Masahiko Nakata
  • Eijiro Hayata
  • Takeshi Murakoshi
  • Jun Yoshimatsu
  • Kazuhiro Osato
  • Kayo Tanaka
  • Tomoaki Oda
  • Akihiko Sekizawa
  • Takako Shimaoka
  • Isamu Ishiwata
  • Jun Takahashi
  • Tomoaki Ikeda
  • J. Matern. Fetal. Neonatal. Med..2020 Jul;:1-6. doi: 10.1080/14767058.2020.1786511.Epub 2020-07-16.

消化管平滑筋腫瘍:407例における予後の特徴の解析

Smooth muscle tumors of the gastrointestinal tract: an analysis of prognostic features in 407 cases.
  • Lindsay Alpert
  • Ram Al-Sabti
  • Rondell P Graham
  • Rish K Pai
  • Raul S Gonzalez
  • Xuefeng Zhang
  • Vanessa Smith
  • Hanlin L Wang
  • Lindsey Westbrook
  • John R Goldblum
  • Ahmed Bakhshwin
  • Sindhu Shetty
  • David S Klimstra
  • Jinru Shia
  • Gokce Askan
  • Marie E Robert
  • Courtney Thomas
  • Wendy L Frankel
  • Mohammed Alsomali
  • Catherine Hagen
  • Mohamed E Mostafa
  • Michael M Feely
  • Naziheh Assarzadegan
  • Joseph Misdraji
  • Angela R Shih
  • Diana Agostini-Vulaj
  • Jeanne M Meis
  • Sherry Tang
  • Deyali Chatterjee
  • Liang-I Kang
  • John Hart
  • Sang Mee Lee
  • Theresa Smith
  • Rhonda K Yantiss
  • Erika M Hissong
  • Zu-Hua Gao
  • JingBo Wu
  • Murray B Resnick
  • Elizabeth Yiru Wu
  • Reet K Pai
  • Lei Zhao
  • Leona A Doyle
  • Shefali Chopra
  • Nicole C Panarelli
  • Shaomin Hu
  • Teri A Longacre
  • Shyam Sampath Raghavan
  • Gregory Y Lauwers
  • Masoumeh Ghayouri
  • Harry S Cooper
  • Rajeswari Nagarathinam
  • Andrew M Bellizzi
  • Sanjay Kakar
  • Mojgan Hosseini
  • Juan Rong
  • Joel K Greenson
  • Laura W Lamps
  • Zachary Dong
  • Mary P Bronner
  • Mod. Pathol..2020 Jul;33(7):1410-1419. 10.1038/s41379-020-0492-5. doi: 10.1038/s41379-020-0492-5.Epub 2020-02-12.

脊髄軟骨腫のヘリカルトモセラピー。30例のコホートを対象としたフランスの多中心的、レトロスペクティブ研究

Helical tomotherapy of spinal chordomas: French Multicentric, retrospective study of a cohort of 30 cases.
  • Maxime Bobin
  • Christina Zacharatou
  • Paul Sargos
  • Véronique Brouste
  • Albert Lisbona
  • Marc-André Mahé
  • Georges Noël
  • Amandine Halley
  • Loïc Feuvret
  • Louis Gras
  • Stéphanie Hoppe
  • Bénédicte Henriques de Figueiredo
  • Guy Kantor
  • Radiat Oncol.2017 Jan;12(1):32. 10.1186/s13014-017-0768-1. doi: 10.1186/s13014-017-0768-1.Epub 2017-01-31.