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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

Canadian Longitudinal Study on Agingのベースラインデータを用いて、45~64歳の女性におけるうつ病、ホルモン療法、および更年期移行について検討した

Depression, hormone therapy, and the menopausal transition among women aged 45 to 64 years using Canadian Longitudinal Study on aging baseline data.
  • Alison K Shea
  • Nazmul Sohel
  • Anne Gilsing
  • Alexandra J Mayhew
  • Lauren E Griffith
  • Parminder Raina
  • Menopause.2020 Jul;27(7):763-770. doi: 10.1097/GME.0000000000001540.

神経集中治療におけるマイクロダイアリシスと近接拡張アッセイ技術を用いたヒト外傷性脳損傷における炎症のタンパク質バイオマーカーのモニタリング

Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care.
  • Philip Dyhrfort
  • Qiujin Shen
  • Fredrik Clausen
  • Måns Thulin
  • Per Enblad
  • Masood Kamali-Moghaddam
  • Anders Lewén
  • Lars Hillered
  • J. Neurotrauma.2019 10;36(20):2872-2885. doi: 10.1089/neu.2018.6320.Epub 2019-06-17.

ダニ細胞株の実験室株と新規ノミ由来のフィールド株の単離と伝播

Isolation and Propagation of Laboratory Strains and a Novel Flea-Derived Field Strain of in Tick Cell Lines.
  • Jing Jing Khoo
  • Timothy J Kurtti
  • Nurul Aini Husin
  • Alexandra Beliavskaia
  • Fang Shiang Lim
  • Mulya Mustika Sari Zulkifli
  • Alaa M Al-Khafaji
  • Catherine Hartley
  • Alistair C Darby
  • Grant L Hughes
  • Sazaly AbuBakar
  • Benjamin L Makepeace
  • Lesley Bell-Sakyi
  • Microorganisms.2020 Jul;8(7). E988. doi: 10.3390/microorganisms8070988.Epub 2020-07-01.

EPR分光法によるヒト40Sリボソームサブユニットと短鎖RNAの相互作用の解明

Exploring the interactions of short RNAs with the human 40S ribosomal subunit near the mRNA entry site by EPR spectroscopy.
  • Alexey A Malygin
  • Olesya A Krumkacheva
  • Dmitri M Graifer
  • Ivan O Timofeev
  • Anastasia S Ochkasova
  • Maria I Meschaninova
  • Alya G Venyaminova
  • Matvey V Fedin
  • Michael Bowman
  • Galina G Karpova
  • Elena G Bagryanskaya
  • Nucleic Acids Res..2019 12;47(22):11850-11860. 5625535. doi: 10.1093/nar/gkz1039.

70歳未満の患者における修復不能な後臼蓋腱板断裂の治療のための逆全肩関節形成術と比較して、上層カプセル再建後の最短2年間の臨床成績

Minimum 2-year clinical outcomes after superior capsule reconstruction compared with reverse total shoulder arthroplasty for the treatment of irreparable posterosuperior rotator cuff tears in patients younger than 70 years.
  • Lucca Lacheta
  • Marilee P Horan
  • Brandon T Goldenberg
  • Grant J Dornan
  • Brendan Higgins
  • Peter J Millett
  • J Shoulder Elbow Surg.2020 Jun;S1058-2746(20)30303-7. doi: 10.1016/j.jse.2020.04.002.Epub 2020-06-09.

腎機能障害を有するサルコイドーシス患者における1,25ジヒドロキシビタミンDの増加

Increase of 1,25 dihydroxyvitamin D in sarcoidosis patients with renal dysfunction.
  • Naoya Toriu
  • Keiichi Sumida
  • Masahiko Oguro
  • Yoichi Oshima
  • Hiroki Mizuno
  • Eiko Hasegawa
  • Tatsuya Suwabe
  • Masahiro Kawada
  • Toshiharu Ueno
  • Noriko Hayami
  • Akinari Sekine
  • Rikako Hiramatsu
  • Masayuki Yamanouchi
  • Junichi Hoshino
  • Naoki Sawa
  • Kenmei Takaichi
  • Kenichi Ohashi
  • Keiichi Kinowaki
  • Takeshi Fujii
  • Ryosuke Date
  • Yoshifumi Ubara
  • Clin. Exp. Nephrol..2019 Oct;23(10):1202-1210. 10.1007/s10157-019-01760-3. doi: 10.1007/s10157-019-01760-3.Epub 2019-06-25.

最近発症した1型糖尿病患者における全原性脂肪組織由来の間質/幹細胞とビタミンDの補給。3ヶ月間の追跡調査パイロット試験

Allogenic Adipose Tissue-Derived Stromal/Stem Cells and Vitamin D Supplementation in Patients With Recent-Onset Type 1 Diabetes Mellitus: A 3-Month Follow-Up Pilot Study.
  • Debora B Araujo
  • Joana R Dantas
  • Karina R Silva
  • Débora L Souto
  • Maria de Fátima C Pereira
  • Jessica P Moreira
  • Ronir R Luiz
  • Cesar S Claudio-Da-Silva
  • Monica A L Gabbay
  • Sergio A Dib
  • Carlos E B Couri
  • Angelo Maiolino
  • Carmen L K Rebelatto
  • Debora R Daga
  • Alexandra C Senegaglia
  • Paulo R S Brofman
  • Leandra Santos Baptista
  • José E P Oliveira
  • Lenita Zajdenverg
  • Melanie Rodacki
  • Front Immunol.2020;11:993. doi: 10.3389/fimmu.2020.00993.Epub 2020-06-02.

マウス胚性幹細胞のRNAディープシーケンシング解析により同定された化学物質の有害性スクリーニングのためのマイクロRNAバイオマーカー

MicroRNA biomarkers for chemical hazard screening identified by RNA deep sequencing analysis in mouse embryonic stem cells.
  • Hiroshi Aoki
  • Hidenori Tani
  • Kaoru Nakamura
  • Hiroaki Sato
  • Masaki Torimura
  • Tetsuya Nakazato
  • Toxicol. Appl. Pharmacol..2020 Apr;392:114929. S0041-008X(20)30053-3. doi: 10.1016/j.taap.2020.114929.Epub 2020-02-24.

カルシウム酸。24,25-ジヒドロキシビタミンDで処理したマウスの血清中の25-ヒドロキシビタミンDの末端C24-酸化生成物および関連する中間体のin vivoでの検出および定量

Calcioic acid: In vivo detection and quantification of the terminal C24-oxidation product of 25-hydroxyvitamin D and related intermediates in serum of mice treated with 24,25-dihydroxyvitamin D.
  • Martin Kaufmann
  • Corine Martineau
  • Alice Arabian
  • Mary Traynor
  • René St-Arnaud
  • Glenville Jones
  • J. Steroid Biochem. Mol. Biol..2019 04;188:23-28. S0960-0760(18)30521-1. doi: 10.1016/j.jsbmb.2018.12.001.Epub 2018-12-13.

miR-122ノックアウトマウスにおけるRelBのアップレギュレーションは、肝臓およびマクロファージにおける炎症性ケモカイン/サイトカインレベルの上昇に寄与する

Upregulation of RelB in the miR-122 knockout mice contributes to increased levels of proinflammatory chemokines/cytokines in the liver and macrophages.
  • Ke-Hsun Hsu
  • Chin-Wen Wei
  • Yi-Ru Su
  • Tung Chou
  • Yueh-Ling Lin
  • Fu-Chen Yang
  • Ann-Ping Tsou
  • Chia-Lin Hsu
  • Ping-Hui Tseng
  • Nien-Jung Chen
  • Kuo-Shyang Jeng
  • Chuen-Miin Leu
  • Immunol. Lett..2020 Jul;226:22-30. S0165-2478(20)30346-1. doi: 10.1016/j.imlet.2020.06.015.Epub 2020-07-02.

ヒトPA200とPA200-20Sの複合体の低温電子顕微鏡構造から、プロテアソームのゲート開口とPA200の2つの開口が制御されていることが明らかになった

Cryo-EM structures of the human PA200 and PA200-20S complex reveal regulation of proteasome gate opening and two PA200 apertures.
  • Hongxin Guan
  • Youwang Wang
  • Ting Yu
  • Yini Huang
  • Mianhuan Li
  • Abdullah F U H Saeed
  • Vanja Perčulija
  • Daliang Li
  • Jia Xiao
  • Dongmei Wang
  • Ping Zhu
  • Songying Ouyang
  • PLoS Biol..2020 03;18(3):e3000654. PBIOLOGY-D-19-02639. doi: 10.1371/journal.pbio.3000654.Epub 2020-03-05.

重み付け遺伝子共発現ネットワークと競合内因性RNAネットワーク解析による変形性変形性メニスカスにおけるlncRNAとmRNAのバイオマーカーの同定

Identification of lncRNA and mRNA Biomarkers in Osteoarthritic Degenerative Meniscus by Weighted Gene Coexpression Network and Competing Endogenous RNA Network Analysis.
  • Jun Zhao
  • Yu Su
  • Jianfei Jiao
  • Zhengchun Wang
  • Xiangchun Fang
  • Xuefeng He
  • Xiaofeng Zhang
  • Zhao Liu
  • Xilin Xu
  • Biomed Res Int.2020;2020:2123787. doi: 10.1155/2020/2123787.Epub 2020-05-20.

PHBV/PLA/Col膜のデュラプラスティは、脊髄損傷ラットにおいて、NLRP3複合体とM1マクロファージの分極を抑制することで軸索再生を促進した

Duraplasty of PHBV/PLA/Col membranes promotes axonal regeneration by inhibiting NLRP3 complex and M1 macrophage polarization in rats with spinal cord injury.
  • Tengfei Zhao
  • Kan Xu
  • Qionghua Wu
  • Chenggui Wang
  • Shining Xiao
  • Heyangzi Li
  • Teng He
  • Linlin Wang
  • Fangcai Li
  • Qixin Chen
  • FASEB J..2020 Jul;doi: 10.1096/fj.202000190RR.Epub 2020-07-20.

中等期肝細胞がんの治療戦略を変えるパラダイム:アジア太平洋地域原発性肝がん専門家コンセンサス・ステートメント

A Changing Paradigm for the Treatment of Intermediate-Stage Hepatocellular Carcinoma: Asia-Pacific Primary Liver Cancer Expert Consensus Statements.
  • Masatoshi Kudo
  • Kwang-Hyub Han
  • Sheng-Long Ye
  • Jian Zhou
  • Yi-Hsiang Huang
  • Shi-Ming Lin
  • Chung-Kwe Wang
  • Masafumi Ikeda
  • Stephen Lam Chan
  • Su Pin Choo
  • Shiro Miyayama
  • Ann Lii Cheng
  • Liver Cancer.2020 Jun;9(3):245-260. lic-0009-0245. doi: 10.1159/000507370.Epub 2020-05-13.

炎症は、薬を服用していない双極性障害では、島嶼部の機能的接続性の低下と関連している

Inflammation is associated with decreased functional connectivity of insula in unmedicated bipolar disorder.
  • Pan Chen
  • Feng Chen
  • Guanmao Chen
  • Shuming Zhong
  • JiaYing Gong
  • Hui Zhong
  • Tao Ye
  • Guixian Tang
  • Jurong Wang
  • Zhenye Luo
  • Zhangzhang Qi
  • Yanbin Jia
  • Hengwen Yang
  • Zhinan Yin
  • Li Huang
  • Ying Wang
  • Brain Behav. Immun..2020 Jul;S0889-1591(20)30243-9. doi: 10.1016/j.bbi.2020.07.004.Epub 2020-07-17.

前臨床での抗血栓活性を有する高親和性の経口バイオアベイラブル大環状FXIa阻害剤の発見

Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species.
  • Wu Yang
  • Yufeng Wang
  • Amy Lai
  • Charles G Clark
  • James R Corte
  • Tianan Fang
  • Paul J Gilligan
  • Yoon Jeon
  • Kumar B Pabbisetty
  • Richard A Rampulla
  • Arvind Mathur
  • Mahammed Kaspady
  • Premsai Rai Neithnadka
  • Arunachalam Arumugam
  • Sivashankaran Raju
  • Karen A Rossi
  • Joseph E Myers
  • Steven Sheriff
  • Zhen Lou
  • Joanna J Zheng
  • Silvi A Chacko
  • Jeffrey M Bozarth
  • Yiming Wu
  • Earl J Crain
  • Pancras C Wong
  • Dietmar A Seiffert
  • Joseph M Luettgen
  • Patrick Y S Lam
  • Ruth R Wexler
  • William R Ewing
  • J. Med. Chem..2020 Jul;63(13):7226-7242. doi: 10.1021/acs.jmedchem.0c00464.Epub 2020-06-17.

ダール塩感受性高血圧、腎障害、Tリンパ球トランスクリプトームに対する食事の影響

Dietary Effects on Dahl Salt-Sensitive Hypertension, Renal Damage, and the T Lymphocyte Transcriptome.
  • Justine M Abais-Battad
  • Ammar J Alsheikh
  • Xiaoqing Pan
  • Daniel J Fehrenbach
  • John Henry Dasinger
  • Hayley Lund
  • Michelle L Roberts
  • Alison J Kriegel
  • Allen W Cowley
  • Srividya Kidambi
  • Theodore A Kotchen
  • Pengyuan Liu
  • Mingyu Liang
  • David L Mattson
  • Hypertension.2019 10;74(4):854-863. doi: 10.1161/HYPERTENSIONAHA.119.12927.Epub 2019-09-03.

タイで栽培された27種の植物化学物質、抗酸化物質、体外での抗アルツハイマー性の比較

Comparison of Phytochemicals, Antioxidant, and In Vitro Anti-Alzheimer Properties of Twenty-Seven spp. Cultivated in Thailand.
  • Piya Temviriyanukul
  • Varittha Sritalahareuthai
  • Kriskamol Na Jom
  • Butsara Jongruaysup
  • Somying Tabtimsri
  • Kanchana Pruesapan
  • Sirinapa Thangsiri
  • Woorawee Inthachat
  • Dalad Siriwan
  • Somsri Charoenkiatkul
  • Uthaiwan Suttisansanee
  • Molecules.2020 Jun;25(11). E2600. doi: 10.3390/molecules25112600.Epub 2020-06-03.

インプラント表面のアモルファスカーボン修飾:FAK/ERK1/2シグナル伝達経路を介して多様なバイオマテリアルの骨形成分化を促進するための一般的な戦略

Amorphous carbon modification on implant surface: a general strategy to enhance osteogenic differentiation for diverse biomaterials via FAK/ERK1/2 signaling pathways.
  • Xinran Zhang
  • Haotian Li
  • Jiaqiang Liu
  • Hui Wang
  • Wenjun Sun
  • Kaili Lin
  • Xudong Wang
  • Steve Guofang Shen
  • J Mater Chem B.2019 04;7(15):2518-2533. doi: 10.1039/c8tb02850h.Epub 2019-03-19.

非毒性の青色光(453nm)がヒト皮膚線維芽細胞の細胞抗酸化能、TGF-β1シグナル伝達、および筋線維芽細胞の筋線維形成に与える影響

The impact of non-toxic blue light (453 nm) on cellular antioxidative capacity, TGF-β1 signaling, and myofibrogenesis of human skin fibroblasts.
  • Julia M Krassovka
  • Christoph V Suschek
  • Max Prost
  • Vera Grotheer
  • Jennifer L Schiefer
  • Erhan Demir
  • Paul C Fuchs
  • Joachim Windolf
  • Ewa K Stürmer
  • Christian Opländer
  • J. Photochem. Photobiol. B, Biol..2020 Jul;209:111952. S1011-1344(20)30402-4. doi: 10.1016/j.jphotobiol.2020.111952.Epub 2020-07-06.

大脳皮質発生の奇形における標的的再配列:遺伝子型とフェノタイプの相関関係

Targeted re-sequencing in malformations of cortical development: genotype-phenotype correlations.
  • Andrea Accogli
  • Mariasavina Severino
  • Antonella Riva
  • Francesca Madia
  • Ganna Balagura
  • Michele Iacomino
  • Barbara Carlini
  • Simona Baldassari
  • Thea Giacomini
  • Carolina Croci
  • Livia Pisciotta
  • Tullio Messana
  • Antonella Boni
  • Angelo Russo
  • Leonilda Bilo
  • Rosa Tonziello
  • Antonietta Coppola
  • Alessandro Filla
  • Oriano Mecarelli
  • Rosario Casalone
  • Francesco Pisani
  • Raffaele Falsaperla
  • Silvia Marino
  • Pasquale Parisi
  • Alessandro Ferretti
  • Maurizio Elia
  • Anna Luchetti
  • Donatella Milani
  • Francesca Vanadia
  • Laura Silvestri
  • Erika Rebessi
  • Eliana Parente
  • Giampaolo Vatti
  • Maria Margherita Mancardi
  • Lino Nobili
  • Valeria Capra
  • Vincenzo Salpietro
  • Pasquale Striano
  • Federico Zara
  • Seizure.2020 Jun;80:145-152. S1059-1311(20)30153-9. doi: 10.1016/j.seizure.2020.05.023.Epub 2020-06-03.

ワルデンストロームマクログロブリン血症患者を対象としたイブルチニブ単剤療法の奏効率と生存率 臨床試験のオンとオフの結果について

Response and Survival Outcomes to Ibrutinib Monotherapy for Patients With Waldenström Macroglobulinemia on and off Clinical Trials.
  • Jorge J Castillo
  • Joshua N Gustine
  • Kirsten Meid
  • Catherine A Flynn
  • Maria G Demos
  • Maria L Guerrera
  • Cristina Jimenez
  • Amanda Kofides
  • Xia Liu
  • Manit Munshi
  • Nicholas Tsakmaklis
  • Christopher J Patterson
  • Lian Xu
  • Guang Yang
  • Zachary R Hunter
  • Steven P Treon
  • Hemasphere.2020 Jun;4(3):e363. HemaSphere-2019-0201. doi: 10.1097/HS9.0000000000000363.Epub 2020-05-21.

アフリカトリパノソーマの成長を阻害し、発生制御遺伝子の転写レベルに影響を与える臨床的に承認された低分子の同定

Identification of clinically approved small molecules that inhibit growth and affect transcript levels of developmentally regulated genes in the African trypanosome.
  • Madison Elle Walsh
  • Eleanor Mary Naudzius
  • Savanah Jessica Diaz
  • Theodore William Wismar
  • Mikhail Martchenko Shilman
  • Danae Schulz
  • PLoS Negl Trop Dis.2020 03;14(3):e0007790. PNTD-D-19-01546. doi: 10.1371/journal.pntd.0007790.Epub 2020-03-13.

二硫化モリブデンをポリエーテルエーテルケトンに組み込むことで、機械的性能、トライボロジー性能、細胞適合性を向上させた人工関節用のバイオコンポジットが得られた

Incorporation of molybdenum disulfide into polyetheretherketone creating biocomposites with improved mechanical, tribological performances and cytocompatibility for artificial joints applications.
  • Xinke Lv
  • Xuehong Wang
  • Songchao Tang
  • Dongliang Wang
  • Lili Yang
  • Axiang He
  • Tingting Tang
  • Jie Wei
  • Colloids Surf B Biointerfaces.2020 May;189:110819. S0927-7765(20)30049-7. doi: 10.1016/j.colsurfb.2020.110819.Epub 2020-01-21.

下肢バイパスのための強化された回復プログラムの実施

Implementation of an Enhanced Recovery Program for Lower Extremity Bypass.
  • Adam Witcher
  • John Axley
  • Zdenek Novak
  • Maria Laygo-Prickett
  • Meredith Guthrie
  • Anisa Xhaja
  • Daniel I Chu
  • S Danielle Brokus
  • Emily L Spangler
  • Marc A Passman
  • Katharine L McGinigle
  • Benjamin J Pearce
  • Ryne Schlitz
  • Roland T Short
  • Jeffrey W Simmons
  • Richard C Cross
  • Graeme E McFarland
  • Adam W Beck
  • J. Vasc. Surg..2020 Jul;S0741-5214(20)31581-0. doi: 10.1016/j.jvs.2020.06.106.Epub 2020-07-15.

エレクトロスピンPCLベースのナノファイバー <i>Arrabidaea chica</i> Verlot - <i>Pterodon pubescens</i> Benth loaded:線維芽細胞形成の相乗効果

Electrospun PCL-based nanofibers <i>Arrabidaea chica</i> Verlot - <i>Pterodon pubescens</i> Benth loaded: synergic effect in fibroblast formation.
  • Taís Helena Costa Salles
  • Fabiana Volpe-Zanutto
  • Ilza Maria de Oliveira Sousa
  • Daisy Machado
  • Ana Caroline Zanatta
  • Wagner Vilegas
  • Marcelo Lancellotti
  • Mary Ann Foglio
  • Marcos Akira d'Ávila
  • Biomed Mater.2020 Jun;doi: 10.1088/1748-605X/ab9bb1.Epub 2020-06-11.

血漿脂質バイオマーカー解析により、血管性痴呆における脂質の変化が明らかになった

Plasma lipidomic biomarker analysis reveals distinct lipid changes in vascular dementia.
  • Yue Liu
  • Daniel K Y Chan
  • Anbupalam Thalamuthu
  • Wei Wen
  • Jiyang Jiang
  • Matthew Paradise
  • Teresa Lee
  • John Crawford
  • Matthew Wai Kin Wong
  • Ying Hua Xu
  • Anne Poljak
  • Russell Pickford
  • Perminder S Sachdev
  • Nady Braidy
  • Comput Struct Biotechnol J.2020;18:1613-1624. S2001-0370(20)30289-0. doi: 10.1016/j.csbj.2020.06.001.Epub 2020-06-09.

保存されていないヒト脂肪lincRNAの探索により、脂肪細胞の代謝を制御する役割が明らかになった

Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of in adipocyte metabolism.
  • Xuan Zhang
  • Chenyi Xue
  • Jennie Lin
  • Jane F Ferguson
  • Amber Weiner
  • Wen Liu
  • Yumiao Han
  • Christine Hinkle
  • Wenjun Li
  • Hongfeng Jiang
  • Sager Gosai
  • Melanie Hachet
  • Benjamin A Garcia
  • Brian D Gregory
  • Raymond E Soccio
  • John B Hogenesch
  • Patrick Seale
  • Mingyao Li
  • Muredach P Reilly
  • Sci Transl Med.2018 06;10(446). eaar5987. doi: 10.1126/scitranslmed.aar5987.

炎症性腸疾患の若年患者における仙腸炎の徴候検出における磁気共鳴腸管造影検査の有用性

Usefulness of magnetic resonance enterography in detecting signs of sacroiliitis in young patients with inflammatory bowel disease.
  • Teresa Giani
  • Azzurra Bernardini
  • Massimo Basile
  • Marco Di Maurizo
  • Anna Perrone
  • Sara Renzo
  • Viola Filistrucchi
  • Rolando Cimaz
  • Paolo Lionetti
  • Pediatr Rheumatol Online J.2020 Jun;18(1):42. 10.1186/s12969-020-00433-w. doi: 10.1186/s12969-020-00433-w.Epub 2020-06-03.

天然着色料の分析と生物学的活性。オプンティア種の生物多様性を探索するための分子マーカーとの関連付け

Natural colourants analysis and biological activities. Association to molecular markers to explore the biodiversity of Opuntia species.
  • Nidhal Salem
  • Myriam Lamine
  • Bilel Damergi
  • Fatma Ezahra
  • Nedia Feres
  • Selim Jallouli
  • Majdi Hammami
  • Saber Khammassi
  • Sawsen Selmi
  • Salem Elkahoui
  • Ferid Limam
  • Olfa Tabben
  • Phytochem Anal.2020 Jun;doi: 10.1002/pca.2954.Epub 2020-06-16.