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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

アルツハイマー病の診断のためのAPP/PS1トランスジェニックマウスにおけるクルクミン負荷高分子ミセルを用いた網膜Aβプラークの非侵襲的光学イメージング

Non-invasive optical imaging of retinal Aβ plaques using curcumin loaded polymeric micelles in APP/PS1 transgenic mice for the diagnosis of Alzheimer's disease.
  • Fidelis Chibhabha
  • Yaqi Yang
  • Kuang Ying
  • Fujie Jia
  • Qin Zhang
  • Shahid Ullah
  • Zibin Liang
  • Muke Xie
  • Feng Li
  • J Mater Chem B.2020 Jul;doi: 10.1039/d0tb01101k.Epub 2020-07-14.

長期非経口栄養の適応を有する患者の栄養状態の維持・改善に対する高カロリー・高タンパク処方の有効性に関する実地試験

Real-life study of the effectiveness of a high calorie and high protein formula in the maintenance and improvement of nutritional state in patients with an indication of long-term parenteral nutrition.
  • María D Ballesteros Pomar
  • Patricia Sorribes Carrera
  • Maria Amparo Rodriguez Piñera
  • Antonio José Blanco Orenes
  • Laura Calles Romero
  • Natalia C Iglesias Hernández
  • M Teresa Olivan Usieto
  • Francisca Payeras Mas
  • Margarita Viñuela Benéitez
  • María Merino Viveros
  • Cristina Navea Aguilera
  • Josefina Olivares Alcolea
  • Endocrinol Diabetes Nutr.2020 Jul;S2530-0164(20)30136-1. doi: 10.1016/j.endinu.2020.03.010.Epub 2020-07-06.

遺伝子組換え(株NZYM-CE)由来の食品酵素Endo-1,4-β-キシラナーゼの安全性評価

Safety evaluation of the food enzyme endo-1,4-β-xylanase from a genetically modified (strain NZYM-CE).
  • Vittorio Silano
  • José Manuel Barat Baviera
  • Claudia Bolognesi
  • Beat Johannes Brüschweiler
  • Pier Sandro Cocconcelli
  • Riccardo Crebelli
  • David Michael Gott
  • Konrad Grob
  • Evgenia Lampi
  • Alicja Mortensen
  • Gilles Rivière
  • Inger-Lise Steffensen
  • Christina Tlustos
  • Henk van Loveren
  • Laurence Vernis
  • Holger Zorn
  • Karl-Heinz Engel
  • Sirpa Kärenlampi
  • Jaime Aguilera
  • Davide Arcella
  • Natalia Kovalkovicova
  • Yi Liu
  • Joaquim Maia
  • Andrew Chesson
  • EFSA J.2019 Apr;17(4):e05685. EFS25685. doi: 10.2903/j.efsa.2019.5685.Epub 2019-04-30.

UFM1-Specific Ligase 1 Ligating Enzyme 1は、マウス乳腺上皮細胞におけるJNKシグナル伝達経路を介して乳タンパク質と脂肪合成に関連する遺伝子発現を媒介している

UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells.
  • Meiqian Kuang
  • Min Yang
  • Lian Li
  • Chengmin Li
  • Genlin Wang
  • Oxid Med Cell Longev.2020;2020:4045674. doi: 10.1155/2020/4045674.Epub 2020-06-19.

(-)-リナロールを担持した高分子ナノカプセルは、線維筋痛症治療の候補となる可能性がある

(-)-linalool-Loaded Polymeric Nanocapsules Are a Potential Candidate to Fibromyalgia Treatment.
  • Tatianny de Araujo Andrade
  • Paula Dos Passos Menezes
  • Yasmim Maria Barbosa Gomes de Carvalho
  • Bruno Dos Santos Lima
  • Eloísa Portugal Barros Silva Soares de Souza
  • Adriano Antunes de Souza Araujo
  • Marlange Almeida Oliveira Melo
  • Lucindo José Quintans-Júnior
  • Jullyana de Souza Siqueira Quintans
  • Sílvia Stanisçuaski Guterres
  • Adriana Raffin Pohlmann
  • Saravanan Shanmugam
  • Luiza Abrahão Frank
  • Mairim Russo Serafini
  • AAPS PharmSciTech.2020 Jul;21(5):184. 10.1208/s12249-020-01719-8. doi: 10.1208/s12249-020-01719-8.Epub 2020-07-06.

株DP-Nzh63由来の食品酵素グルカン1,4-α-グルコシダーゼの安全性評価

Safety evaluation of the food enzyme glucan 1,4-α-glucosidase from (strain DP-Nzh63).
  • Vittorio Silano
  • José Manuel Barat Baviera
  • Claudia Bolognesi
  • Pier Sandro Cocconcelli
  • Riccardo Crebelli
  • David Michael Gott
  • Konrad Grob
  • Evgenia Lampi
  • Alicja Mortensen
  • Gilles Rivière
  • Inger-Lise Steffensen
  • Christina Tlustos
  • Henk Van Loveren
  • Laurence Vernis
  • Holger Zorn
  • Boet Glandorf
  • Lieve Herman
  • Jaime Aguilera
  • Magdalena Andryszkiewicz
  • Yi Liu
  • Andrew Chesson
  • EFSA J.2019 Oct;17(10):e05825. EFS25825. doi: 10.2903/j.efsa.2019.5825.Epub 2019-10-17.

切除したBRAF V600E変異大腸肝転移の生存率。日本における多施設レトロスペクティブコホート研究

Survival Outcomes of Resected BRAF V600E Mutant Colorectal Liver Metastases: A Multicenter Retrospective Cohort Study in Japan.
  • Shin Kobayashi
  • Shinichiro Takahashi
  • Naoki Takahashi
  • Toshiki Masuishi
  • Hirokazu Shoji
  • Eiji Shinozaki
  • Tatsuro Yamaguchi
  • Motohiro Kojima
  • Naoto Gotohda
  • Shogo Nomura
  • Takayuki Yoshino
  • Hiroya Taniguchi
  • Ann. Surg. Oncol..2020 Jul;10.1245/s10434-020-08817-8. doi: 10.1245/s10434-020-08817-8.Epub 2020-07-13.

PCV2キャプシドタンパク質のデコイエピトープをPRRSVのエピトープであるGP3やGP5で置換することで、マウスの2価ワクチンの免疫原性が向上することが明らかになった

Replacing the decoy epitope of PCV2 capsid protein with epitopes of GP3 and/or GP5 of PRRSV enhances the immunogenicity of bivalent vaccines in mice.
  • Bo-Kyoung Jung
  • Hye-Ran Kim
  • Huyn Jang
  • Kyung-Soo Chang
  • J. Virol. Methods.2020 Jul;:113928. S0166-0934(20)30180-4. doi: 10.1016/j.jviromet.2020.113928.Epub 2020-07-07.

ベトナムの屋内職場における二次たばこ煙曝露と関連因子。世界成人たばこ調査(GATS)2010年と2015年の2ラウンドからの知見

Secondhand Tobacco Smoke Exposure in Indoor Workplaces in Viet Nam and Associated Factors: Findings from Two Rounds of Global Adult Tobacco Surveys (GATS) 2010 and 2015.
  • Nguyen Tuan Lam
  • Pham Thi Quynh Nga
  • Mina Kashiwabara
  • Phan Thi Hai
  • Doan Thi Thu Huyen
  • Kim Bao Giang
  • Hoang Van Minh
  • Nguyen The Quan
  • Luong Ngoc Khue
  • Kidong Park
  • Asian Pac. J. Cancer Prev..2020 Jul;21(S1):33-38. 89101. doi: 10.31557/APJCP.2020.21.S1.33.Epub 2020-07-01.

ロピナビル/リトナビル、ヒドロキシクロロキン、インターフェロンβ-1bの3剤併用療法で治療した重症COVID-19肺炎患者5例

Five severe COVID-19 pneumonia patients treated with triple combination therapy with lopinavir/ritonavir, hydroxychloroquine, and interferon β-1b.
  • Sun In Hong
  • Byung-Han Ryu
  • Yong Pil Chong
  • Seungjun Lee
  • Sunjoo Kim
  • Ho Cheol Kim
  • Kyung-Wook Hong
  • In-Gyu Bae
  • Oh-Hyun Cho
  • Int. J. Antimicrob. Agents.2020 Jun;:106052. S0924-8579(20)30222-3. doi: 10.1016/j.ijantimicag.2020.106052.Epub 2020-06-13.

脂肪組織由来の間質細胞を刺激したマクロファージと内皮細胞の相互作用により、虚血性筋の効果的な新生血管化が促進される

Adipose tissue-derived stromal cells stimulated macrophages-endothelial cells interactions promote effective ischemic muscle neovascularization.
  • Justyna Czapla
  • Tomasz Cichoń
  • Ewelina Pilny
  • Magdalena Jarosz-Biej
  • Sybilla Matuszczak
  • Alina Drzyzga
  • Łukasz Krakowczyk
  • Ryszard Smolarczyk
  • Eur. J. Pharmacol..2020 Jul;:173354. S0014-2999(20)30446-5. doi: 10.1016/j.ejphar.2020.173354.Epub 2020-07-11.

リポ多糖類(LPS)が血中および脳内の炎症マーカーおよび個別飼育豚の行動に及ぼす影響

The effect of lipopolysaccharide (LPS) on inflammatory markers in blood and brain and on behavior in individually-housed pigs.
  • Janicke Nordgreen
  • Camilla Munsterhjelm
  • Frida Aae
  • Anastasija Popova
  • Preben Boysen
  • Birgit Ranheim
  • Mari Heinonen
  • Joanna Raszplewicz
  • Petteri Piepponen
  • Andreas Lervik
  • Anna Valros
  • Andrew M Janczak
  • Physiol. Behav..2018 10;195:98-111. S0031-9384(18)30507-9. doi: 10.1016/j.physbeh.2018.07.013.Epub 2018-08-02.

イネの初期葉緑体発生に必須のHNHエンドヌクレアーゼドメイン含有タンパク質をコードするWSL9

WSL9 Encodes an HNH Endonuclease Domain-Containing Protein that Is Essential for Early Chloroplast Development in Rice.
  • Xingjie Zhu
  • Changling Mou
  • Fulin Zhang
  • Yunshuai Huang
  • Chunyan Yang
  • Jingli Ji
  • Xi Liu
  • Penghui Cao
  • Thanhliem Nguyen
  • Jie Lan
  • Chunlei Zhou
  • Shijia Liu
  • Ling Jiang
  • Jianmin Wan
  • Rice (N Y).2020 Jul;13(1):45. 10.1186/s12284-020-00407-2. doi: 10.1186/s12284-020-00407-2.Epub 2020-07-11.

豚のリポ多糖チャレンジ後の免疫応答とキヌレニン経路に及ぼす1-メチルトリプトファンの効果

Effects of 1-Methyltryptophan on Immune Responses and the Kynurenine Pathway after Lipopolysaccharide Challenge in Pigs.
  • Elisa Wirthgen
  • Winfried Otten
  • Margret Tuchscherer
  • Armin Tuchscherer
  • Grazyna Domanska
  • Julia Brenmoehl
  • Juliane Günther
  • Daniela Ohde
  • Werner Weitschies
  • Anne Seidlitz
  • Eberhard Scheuch
  • Ellen Kanitz
  • Int J Mol Sci.2018 Oct;19(10). E3009. doi: 10.3390/ijms19103009.Epub 2018-10-02.

スチレンの懸濁重合における還元グラフェン酸化物の役割とポリスチレン/rGOナノコンポジットの形態と熱特性への影響

The Role of Reduced Graphene Oxide in the Suspension Polymerization of Styrene and Its Effect on the Morphology and Thermal Properties of the Polystyrene/rGO Nanocomposites.
  • Marta Sieradzka
  • Janusz Fabia
  • Dorota Biniaś
  • Ryszard Fryczkowski
  • Jarosław Janicki
  • Polymers (Basel).2020 Jun;12(7). E1468. doi: 10.3390/polym12071468.Epub 2020-06-30.

2,3,7,8-テトラクロロジベンゾ-p-ジオキシン誘発アストロサイト活性化および神経細胞死に対するガストロジンを介した保護に対するSSeCKS-TRAF6相互作用の効果

Effect of the SSeCKS-TRAF6 interaction on gastrodin-mediated protection against 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced astrocyte activation and neuronal death.
  • Man Jiao
  • Kaizhi Yin
  • Tao Zhang
  • Changyue Wu
  • Yan Zhang
  • Xinyuan Zhao
  • Qiyun Wu
  • Chemosphere.2019 Jul;226:678-686. S0045-6535(19)30649-6. doi: 10.1016/j.chemosphere.2019.04.003.Epub 2019-04-01.

FeO担持ナフタレン-1-チオール機能化酸化グラフェンナノコンポジットを用いた超音波支援分散型磁気固相抽出法によるヒト血液試料中のカドミウムのスペシエーション

Speciation of cadmium in human blood samples based on FeO-supported naphthalene-1-thiol- functionalized graphene oxide nanocomposite by ultrasound-assisted dispersive magnetic micro solid phase extraction.
  • Masoud Khaleghi Abbasabadi
  • Hamid Shirkhanloo
  • J Pharm Biomed Anal.2020 Jul;189:113455. S0731-7085(20)31341-8. doi: 10.1016/j.jpba.2020.113455.Epub 2020-07-03.

包括的な嚥下障害ケア。A Multidisciplinary Dysphagia Research Society Taskforce Report of Service-Delivery of the COVID-19 Global Pandemic

Dysphagia Care Across the Continuum: A Multidisciplinary Dysphagia Research Society Taskforce Report of Service-Delivery During the COVID-19 Global Pandemic.
  • Anna Miles
  • Nadine P Connor
  • Rinki Varindani Desai
  • Sudarshan Jadcherla
  • Jacqui Allen
  • Martin Brodsky
  • Kendrea L Garand
  • Georgia A Malandraki
  • Timothy M McCulloch
  • Marc Moss
  • Joseph Murray
  • Michael Pulia
  • Luis F Riquelme
  • Susan E Langmore
  • Dysphagia.2020 Jul;10.1007/s00455-020-10153-8. doi: 10.1007/s00455-020-10153-8.Epub 2020-07-11.

豚の馬血清媒介性血管炎における抗酸化物質の役割。川崎病における冠動脈炎の緩和における早期治療への潜在的な関連性

Role of Antioxidants in Horse Serum-mediated Vasculitis in Swine: Potential Relevance to Early Treatment in Mitigation of Coronary Arteritis in Kawasaki Disease.
  • Saji Philip
  • Wen-Chuan Lee
  • Kotturathu Mammen Cherian
  • Mei-Hwan Wu
  • Hung-Chi Lue
  • Pediatr Neonatol.2017 08;58(4):328-337. S1875-9572(16)30369-2. doi: 10.1016/j.pedneo.2016.07.007.Epub 2016-12-18.

急性腎不全と腎代替療法を受けたCOVID-19患者の有病率、特徴、危険因子、転帰

Prevalence, Characteristics, Risk Factors, and Outcomes of Invasively Ventilated COVID-19 Patients with Acute Kidney Injury and Renal Replacement Therapy.
  • Evgeny V Fominskiy
  • Anna Mara Scandroglio
  • Giacomo Monti
  • Maria Grazia Calabrò
  • Giovanni Landoni
  • Antonio Dell'Acqua
  • Luigi Beretta
  • Elena Moizo
  • Alfredo Ravizza
  • Fabrizio Monaco
  • Corrado Campochiaro
  • Marina Pieri
  • Maria Luisa Azzolini
  • Giovanni Borghi
  • Martina Crivellari
  • Caterina Conte
  • Cristina Mattioli
  • Paolo Silvani
  • Milena Mucci
  • Stefano Turi
  • Stefano Tentori
  • Martina Baiardo Redaelli
  • Marianna Sartorelli
  • Piera Angelillo
  • Alessandro Belletti
  • Pasquale Nardelli
  • Francesco Giuseppe Nisi
  • Gabriele Valsecchi
  • Cristina Barberio
  • Fabio Ciceri
  • Ary Serpa Neto
  • Lorenzo Dagna
  • Rinaldo Bellomo
  • Alberto Zangrillo
  • Blood Purif..2020 Jul;:1-8. 000508657. doi: 10.1159/000508657.Epub 2020-07-13.

デジタルサブトラクション血管造影画像による肝癌のインターベンション化学塞栓術後の感染症と神経障害合併症の相関因子分析

Correlation Factor Analysis of Infections and Neurological Complications after Interventional Chemoembolization of Liver Cancer by Digital Subtraction Angiography Images.
  • Mengyan Xing
  • Zhonghua Ma
  • Hanfang Fu
  • Fang Jin
  • Jing Wang
  • Yujie Hua
  • Li Han
  • Neurosci. Lett..2020 Jun;:135200. S0304-3940(20)30470-5. doi: 10.1016/j.neulet.2020.135200.Epub 2020-06-22.

複数の国際的なマウス施設におけるC57BL/6Nサブラインのオスマウスにおける足根損傷の発生

The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities.
  • Eleanor Herbert
  • Michelle Stewart
  • Marie Hutchison
  • Ann M Flenniken
  • Dawei Qu
  • Lauryl M J Nutter
  • Colin McKerlie
  • Liane Hobson
  • Brenda Kick
  • Bonnie Lyons
  • Jean-Paul Wiegand
  • Rosalinda Doty
  • Juan Antonio Aguilar-Pimentel
  • Martin Hrabe de Angelis
  • Mary Dickinson
  • John Seavitt
  • Jacqueline K White
  • Cheryl L Scudamore
  • Sara Wells
  • PLoS ONE.2020;15(6):e0230162. PONE-D-20-05114. doi: 10.1371/journal.pone.0230162.Epub 2020-06-15.

急性期入院リハビリテーションにおける気管内脊椎脊髄損傷患者における気管内人工呼吸と中等度の換気量の比較:レトロスペクティブコホート研究

Comparing outcomes of mechanical ventilation with high vs. moderate tidal volumes in tracheostomized patients with spinal cord injury in acute inpatient rehabilitation setting: a retrospective cohort study.
  • Radha Korupolu
  • Argyrios Stampas
  • Hannah Uhlig-Reche
  • Ellia Ciammaichella
  • Patrick John Mollett
  • Emmanuel Chigozie Achilike
  • Claudia Pedroza
  • Spinal Cord.2020 Jul;10.1038/s41393-020-0517-4. doi: 10.1038/s41393-020-0517-4.Epub 2020-07-09.

プラズモンは反応経路を変えられるか?非対称ヨードニウム塩の分解を有機物のプローブとする

Can Plasmon Change Reaction Path? Decomposition of Unsymmetrical Iodonium Salts as an Organic Probe.
  • Elena Miliutina
  • Olga Guselnikova
  • Natalia S Soldatova
  • Polina Bainova
  • Roman Elashnikov
  • Přemysl Fitl
  • Theo Kurten
  • Mekhman S Yusubov
  • Václav Švorčík
  • Rashid R Valiev
  • Mohamed M Chehimi
  • Oleksiy Lyutakov
  • Pavel S Postnikov
  • J Phys Chem Lett.2020 Jul;:5770-5776. doi: 10.1021/acs.jpclett.0c01350.Epub 2020-07-07.

神経障害の症状と変化.遺伝性トランスサイレチンアミロイドーシスに対するイノテルセン治療

Neuropathy Symptom and Change: Inotersen Treatment of Hereditary Transthyretin Amyloidosis.
  • P James B Dyck
  • Teresa Coelho
  • Marcia Waddington Cruz
  • Thomas H Brannagan
  • Sami Khella
  • Chafic Karam
  • John L Berk
  • Michael J Polydefkis
  • John C Kincaid
  • Janice F Wiesman
  • William J Litchy
  • Michelle L Mauermann
  • Elizabeth J Ackermann
  • Brenda F Baker
  • Shiangtung W Jung
  • Spencer Guthrie
  • Michael Pollock
  • Peter J Dyck
  • Muscle Nerve.2020 Jul;doi: 10.1002/mus.27023.Epub 2020-07-12.

タンブリンは、Zanthoxylum armatum DCの果実のメタノール抽出物の主要な活性化合物であり、サイクリックAMPとサイクリックGMPの弛緩経路を介して、ブタの冠動脈輪の内皮非依存性弛緩を引き起こします

Tambulin is a major active compound of a methanolic extract of fruits of Zanthoxylum armatum DC causing endothelium-independent relaxations in porcine coronary artery rings via the cyclic AMP and cyclic GMP relaxing pathways.
  • Muhammad Naveed Mushtaq
  • Sushmita Ghimire
  • Alamgeer
  • Muhammad Shoaib Akhtar
  • Achyut Adhikari
  • Cyril Auger
  • Valérie B Schini-Kerth
  • Phytomedicine.2019 Feb;53:163-170. S0944-7113(18)30301-5. doi: 10.1016/j.phymed.2018.09.020.Epub 2018-09-05.

主な単発性自己炎症性疾患とPFAPA症候群に対する現在の治療選択肢.エビデンスに基づいたアプローチと実践ガイドの提案

Current Therapeutic Options for the Main Monogenic Autoinflammatory Diseases and PFAPA Syndrome: Evidence-Based Approach and Proposal of a Practical Guide.
  • Alessandra Soriano
  • Marco Soriano
  • Gerard Espinosa
  • Raffaele Manna
  • Giacomo Emmi
  • Luca Cantarini
  • José Hernández-Rodríguez
  • Front Immunol.2020;11:865. doi: 10.3389/fimmu.2020.00865.Epub 2020-06-03.

心房細動のタイプ、心不全、高齢と心房細動における左房血栓のリスクとの関連としての左房付属器空輸速度の低下

Decreased left atrial appendage emptying velocity as a link between atrial fibrillation type, heart failure and older age and the risk of left atrial thrombus in atrial fibrillation.
  • Monika Gawałko
  • Monika Budnik
  • Beata Uziębło-Życzkowska
  • Paweł Krzesiński
  • Piotr Scisło
  • Janusz Kochanowski
  • Agnieszka Jurek
  • Marek Kiliszek
  • Grzegorz Gielerak
  • Krzysztof J Filipiak
  • Grzegorz Opolski
  • Agnieszka Kapłon-Cieślicka
  • Int. J. Clin. Pract..2020 Jul;:e13609. doi: 10.1111/ijcp.13609.Epub 2020-07-12.

エンテロバクターA47が分泌する細菌性フコース多糖類をベースとした銀ナノコンポジットの創傷被覆用途への応用。合成、特性評価およびin vitro生物活性

Silver nanocomposites based on the bacterial fucose-rich polysaccharide secreted by Enterobacter A47 for wound dressing applications: Synthesis, characterization and in vitro bioactivity.
  • Patrícia Concórdio-Reis
  • Carolina V Pereira
  • Miguel P Batista
  • Chantal Sevrin
  • Christian Grandfils
  • Ana C Marques
  • Elvira Fortunato
  • Frédéric B Gaspar
  • Ana A Matias
  • Filomena Freitas
  • Maria A M Reis
  • Int. J. Biol. Macromol..2020 Jul;S0141-8130(20)33823-X. doi: 10.1016/j.ijbiomac.2020.07.072.Epub 2020-07-09.