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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

ロングノンコーディングRNA SNHG12は、腎細胞癌におけるCDCA3のアップレギュレーションにより、腫瘍の進行とスニチニブ抵抗性を促進する

Long noncoding RNA SNHG12 promotes tumour progression and sunitinib resistance by upregulating CDCA3 in renal cell carcinoma.
  • Yuenan Liu
  • Gong Cheng
  • Ziwei Huang
  • Lin Bao
  • Jingchong Liu
  • Cheng Wang
  • Zhiyong Xiong
  • Lijie Zhou
  • Tianbo Xu
  • Di Liu
  • Hongmei Yang
  • Ke Chen
  • Xiaoping Zhang
  • Cell Death Dis.2020 Jul;11(7):515. 10.1038/s41419-020-2713-8. doi: 10.1038/s41419-020-2713-8.Epub 2020-07-08.

臨床分離株における低レベルポリミキシン耐性検出の難しさ:Rapid Polymyxin NPテスト、Colispotテスト、SuperPolymyxin培地の評価

Difficulty in detecting low levels of polymyxin resistance in clinical isolates: evaluation of Rapid Polymyxin NP test, Colispot Test and SuperPolymyxin medium.
  • O C Conceição-Neto
  • B S da Costa
  • L S Pontes
  • I C O Santos
  • M C Silveira
  • J R Cordeiro-Moura
  • N F Pereira
  • C B Tavares-Teixeira
  • R C Picão
  • C M Rocha-de-Souza
  • A P D Carvalho-Assef
  • New Microbes New Infect.2020 Jul;36:100722. S2052-2975(20)30074-3. doi: 10.1016/j.nmni.2020.100722.Epub 2020-06-25.

Frontline Science.TNF-αとGM-CSF1のプライミングは、Ras、PI3K-γ、好中球プロ炎症反応の活性化を促進するSOS1/2の役割を増大させる

Frontline Science: TNF-α and GM-CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K-γ, and neutrophil proinflammatory responses.
  • Sabine Suire
  • Fernando C Baltanas
  • Anne Segonds-Pichon
  • Keith Davidson
  • Eugenio Santos
  • Phillip T Hawkins
  • Len R Stephens
  • J. Leukoc. Biol..2019 10;106(4):815-822. doi: 10.1002/JLB.2HI0918-359RR.Epub 2019-02-05.

高リスクの心臓外科手術における死亡率を予測するための加算ロジスティック・ヨーロッパ心臓手術リスクシステム(EuroSCORE)とEuroSCORE 2の比較

Comparison of the additive, logistic european system for cardiac operative risk (EuroSCORE) with the EuroSCORE 2 to predict mortality in high-risk cardiac surgery.
  • Laura Guillet
  • Pierre H Moury
  • Damien Bedague
  • Michel Durand
  • Cécile Martin
  • Jean F Payen
  • Olivier Chavanon
  • Pierre Albaladejo
  • Ann Card Anaesth.2020 Jul-Sep;23(3):277-282. AnnCardAnaesth_2020_23_3_277_290043. doi: 10.4103/aca.ACA_209_18.

肝臓でのブドウ糖の利用率が低いと、外因性高コレステロール血症ラットの食事誘発性高コレステロール血症を引き起こす

Low utilization of glucose in the liver causes diet-induced hypercholesterolemia in exogenously hypercholesterolemic rats.
  • Yasutake Tanaka
  • Masahiro Ono
  • Motonori Miyago
  • Takahisa Suzuki
  • Yurika Miyazaki
  • Michio Kawano
  • Makoto Asahina
  • Bungo Shirouchi
  • Katsumi Imaizumi
  • Masao Sato
  • PLoS ONE.2020;15(3):e0229669. PONE-D-19-24869. doi: 10.1371/journal.pone.0229669.Epub 2020-03-12.

1 日 1 回経口投与の新規 5-リポオキシゲナーゼ活性化蛋白質阻害薬 AZD5718 の初期臨床経験

Initial Clinical Experience with AZD5718, a Novel Once Daily Oral 5-Lipoxygenase Activating Protein Inhibitor.
  • Hans Ericsson
  • Karin Nelander
  • Maria Lagerstrom-Fermer
  • Clare Balendran
  • Maria Bhat
  • Ligia Chialda
  • Li-Ming Gan
  • Maria Heijer
  • Magnus Kjaer
  • John Lambert
  • Eva-Lotte Lindstedt
  • Gun-Britt Forsberg
  • Carl Whatling
  • Stanko Skrtic
  • Clin Transl Sci.2018 05;11(3):330-338. doi: 10.1111/cts.12546.Epub 2018-03-08.

小さなカエルが長い道のりを飛躍させる:小さな東洋のカエル属(両生類:Microhylidae)で発見されたインド亜大陸の複合的な植民地化

A little frog leaps a long way: compounded colonizations of the Indian Subcontinent discovered in the tiny Oriental frog genus (Amphibia: Microhylidae).
  • Vladislav A Gorin
  • Evgeniya N Solovyeva
  • Mahmudul Hasan
  • Hisanori Okamiya
  • D M S Suranjan Karunarathna
  • Parinya Pawangkhanant
  • Anslem de Silva
  • Watinee Juthong
  • Konstantin D Milto
  • Luan Thanh Nguyen
  • Chatmongkon Suwannapoom
  • Alexander Haas
  • David P Bickford
  • Indraneil Das
  • Nikolay A Poyarkov
  • PeerJ.2020;8:e9411. 9411. doi: 10.7717/peerj.9411.Epub 2020-07-03.

可溶性血管内皮増殖因子受容体-1に対する内皮細胞の接着は、細胞の動態と血管新生の表現型を誘発する

Endothelial cell adhesion to soluble vascular endothelial growth factor receptor-1 triggers a cell dynamic and angiogenic phenotype.
  • Angela Orecchia
  • Amel Mettouchi
  • Paolo Uva
  • Glenn C Simon
  • Diego Arcelli
  • Simona Avitabile
  • Gianluca Ragone
  • Guerrino Meneguzzi
  • Karl H Pfenninger
  • Giovanna Zambruno
  • Cristina Maria Failla
  • FASEB J..2014 Feb;28(2):692-704. fj.12-225771. doi: 10.1096/fj.12-225771.Epub 2013-10-30.

血清性抗リン脂質症候群の診断におけるアネキシンA5抵抗性と非基準抗体の意義

Annexin-A5 resistance and non-criteria antibodies for the diagnosis of seronegative antiphospholipid syndrome.
  • Théo Ghelfenstein Ferreira
  • François Delhommeau
  • Catherine Johanet
  • Grigorios Gerotziafas
  • Marie Bornes
  • Jonathan Cohen
  • Gilles Kayem
  • Olivier Fain
  • Virginie Planche
  • Arsene Mékinian
  • Clin. Rheumatol..2020 Apr;39(4):1167-1171. 10.1007/s10067-019-04915-5. doi: 10.1007/s10067-019-04915-5.Epub 2020-01-10.

胎児の心室セプタムが無傷の肺動脈性心房症に対する胎児心臓インターベンション:国際胎児心臓インターベンション・レジストリ(IFCIR)

Fetal Cardiac Intervention for Pulmonary Atresia with Intact Ventricular Septum: International Fetal Cardiac Intervention Registry.
  • Whitnee J Hogan
  • Sofia Grinenco
  • Aimee Armstrong
  • Roland Devlieger
  • Joanna Dangel
  • Queralt Ferrer
  • Michele Frommelt
  • Alberto Galindo
  • Helena Gardiner
  • Sarah Gelehrter
  • Ulrike Herberg
  • Lisa Howley
  • Edgar Jaeggi
  • Joana Miranda
  • Shaine A Morris
  • Dick Oepkes
  • Simone Pedra
  • Renuka Peterson
  • Gary Sholler
  • John Simpson
  • James Strainic
  • Trisha V Vigneswarran
  • Annette Wacker-Gussmann
  • Anita J Moon-Grady
  • Fetal. Diagn. Ther..2020 Jul;:1-9. 000508045. doi: 10.1159/000508045.Epub 2020-07-07.

アジアのびらん性食道炎患者を対象に、ランソプラゾールと比較したフォノプラザンの有効性と安全性を評価する第Ⅲ相無作為化二重盲検多施設共同試験

Phase III, randomised, double-blind, multicentre study to evaluate the efficacy and safety of vonoprazan compared with lansoprazole in Asian patients with erosive oesophagitis.
  • Yinglian Xiao
  • Shutian Zhang
  • Ning Dai
  • Guijun Fei
  • Khean-Lee Goh
  • Hoon Jai Chun
  • Bor-Shyang Sheu
  • Chui Fung Chong
  • Nobuo Funao
  • Wen Zhou
  • Minhu Chen
  • Gut.2020 02;69(2):224-230. gutjnl-2019-318365. doi: 10.1136/gutjnl-2019-318365.Epub 2019-08-13.

ゲノムワイドなスクリーニングにより、女性の性器管のコロニー化とウイルス性を促進するA群連鎖球菌表面タンパク質が同定された

Genome-Wide Screens Identify Group A Streptococcus Surface Proteins Promoting Female Genital Tract Colonization and Virulence.
  • Luchang Zhu
  • Randall J Olsen
  • Stephen B Beres
  • Matthew Ojeda Saavedra
  • Samantha L Kubiak
  • Concepcion C Cantu
  • Leslie Jenkins
  • Prasanti Yerramilli
  • Layne Pruitt
  • Amelia R L Charbonneau
  • Andrew S Waller
  • James M Musser
  • Am. J. Pathol..2020 04;190(4):862-873. S0002-9440(20)30018-3. doi: 10.1016/j.ajpath.2019.12.003.Epub 2020-03-19.

閉経後出血を伴う女性における主観的パターン認識による子宮内膜癌の超音波診断:プロスペクティブな評価者間の一致度と信頼性に関する研究

Ultrasound diagnosis of endometrial cancer by subjective pattern recognition in women with postmenopausal bleeding: a prospective inter-rater agreement and reliability study.
  • M Wong
  • N Thanatsis
  • T Amin
  • E Bean
  • K Madhvani
  • D Jurkovic
  • Ultrasound Obstet Gynecol.2020 Jul;doi: 10.1002/uog.22141.Epub 2020-07-04.

ヒト胚性幹細胞由来の筋原性前駆細胞から設計された骨格筋構築物は、EGM-2サプリメントを含む培地中で分化したときに拡張された収縮力を展示しています

Skeletal Muscle Constructs Engineered from Human Embryonic Stem Cell Derived Myogenic Progenitors Exhibit Enhanced Contractile Forces When Differentiated in a Medium Containing EGM-2 Supplements.
  • Bin Xu
  • Mengen Zhang
  • Rita C R Perlingeiro
  • Wei Shen
  • Adv Biosyst.2019 Dec;3(12):e1900005. doi: 10.1002/adbi.201900005.Epub 2019-11-04.

メチオニン残基の酸化は、高閾値熱感受性イオンチャネルTRPV2を活性化する

Oxidation of methionine residues activates the high-threshold heat-sensitive ion channel TRPV2.
  • Tabea C Fricke
  • Frank Echtermeyer
  • Johannes Zielke
  • Jeanne de la Roche
  • Milos R Filipovic
  • Stéphane Claverol
  • Christine Herzog
  • Makoto Tominaga
  • Ruth A Pumroy
  • Vera Y Moiseenkova-Bell
  • Peter M Zygmunt
  • Andreas Leffler
  • Mirjam J Eberhardt
  • Proc. Natl. Acad. Sci. U.S.A..2019 11;116(48):24359-24365. 1904332116. doi: 10.1073/pnas.1904332116.Epub 2019-11-12.

大規模なセーフティネット病院における非定型腺細胞の割合の高さは、疾患の発生率の高さと相関するか?

Do High Rates of Atypical Glandular Cells Correlate With Higher Incidence of Disease in a Large Safety Net Hospital.
  • Theresa Kuhn
  • Catherine Finneran
  • Adrian Kohut
  • Emily Wang
  • George Birdsong
  • Uma Krishnamurti
  • Marina Mosunjac
  • Talaat Tadros
  • Gabriela Oprea
  • Vaidehi Avadhani
  • Shae Boguslawski
  • Samantha Karlow
  • Peter Schnatz
  • Namita Khanna
  • Lisa Flowers
  • J Low Genit Tract Dis.2020 Jun;doi: 10.1097/LGT.0000000000000556.Epub 2020-06-17.

慢性ストレス下での神経血管カップリングはGABA作動性神経細胞間葉系活動の変化によって変化する.

Neurovascular Coupling under Chronic Stress Is Modified by Altered GABAergic Interneuron Activity.
  • Kayoung Han
  • Jiwoong Min
  • Myunghee Lee
  • Bok-Man Kang
  • Taeyoung Park
  • Junghyun Hahn
  • Jaeseung Yei
  • Juheon Lee
  • Junsung Woo
  • C Justin Lee
  • Seong-Gi Kim
  • Minah Suh
  • J. Neurosci..2019 12;39(50):10081-10095. JNEUROSCI.1357-19.2019. doi: 10.1523/JNEUROSCI.1357-19.2019.Epub 2019-10-31.

自然細胞死と細菌性病害抵抗性の向上を示すイネ病巣擬態変異体oshpl3の特性と遺伝学的解析

Characterization and genetic analysis of the oshpl3 rice lesion mimic mutant showing spontaneous cell death and enhanced bacterial blight resistance.
  • Ranran Tu
  • Hong Wang
  • Qunen Liu
  • Dongfei Wang
  • Xingpeng Zhou
  • Peng Xu
  • Yinxing Zhang
  • Weixun Wu
  • Daibo Chen
  • Liyong Cao
  • Shihua Cheng
  • Xihong Shen
  • Plant Physiol. Biochem..2020 May;154:94-104. S0981-9428(20)30215-1. doi: 10.1016/j.plaphy.2020.05.001.Epub 2020-05-08.

ツバ・メラノスポラム(Tuber melanosporum)とツバ・インディカム(Tuber indicum)による植民地化は、根圏におけるマツ・アーマンディ(Pinus armandii)の生育とphoDアルカリホスファターゼをコードする細菌群集に影響を与えることがわかった

Colonization by Tuber melanosporum and Tuber indicum affects the growth of Pinus armandii and phoD alkaline phosphatase encoding bacterial community in the rhizosphere.
  • Xiaoping Zhang
  • Xiaolin Li
  • Lei Ye
  • Yue Huang
  • Zongjing Kang
  • Bo Zhang
  • Xiaoping Zhang
  • Microbiol. Res..2020 Jun;239:126520. S0944-5013(20)30388-8. doi: 10.1016/j.micres.2020.126520.Epub 2020-06-03.

古代のゲノムから明らかになった中国のカシミア生産ヤギの進化の歴史と起源

Ancient Genomes Reveal the Evolutionary History and Origin of Cashmere-Producing Goats in China.
  • Yudong Cai
  • Weiwei Fu
  • Dawei Cai
  • Rasmus Heller
  • Zhuqing Zheng
  • Jia Wen
  • Hui Li
  • Xiaolong Wang
  • Akil Alshawi
  • Zhouyong Sun
  • Siqi Zhu
  • Juan Wang
  • Miaomiao Yang
  • Songmei Hu
  • Yan Li
  • Zhirui Yang
  • Mian Gong
  • Yunan Hou
  • Tianming Lan
  • Kui Wu
  • Yulin Chen
  • Yu Jiang
  • Xihong Wang
  • Mol. Biol. Evol..2020 Jul;37(7):2099-2109. 5824306. doi: 10.1093/molbev/msaa103.

臍帯血移植患者を対象とした移植前播種性フザリヌス菌症の高用量リポソーマルアムホテリシンB投与による治療に成功した

[Successful treatment of pre-engraftment disseminated fusariosis with high-dose liposomal amphotericin B in a cord blood transplant recipient].
  • Yasuhiko Harada
  • Makoto Murata
  • Akane Matsumoto
  • Daizo Kato
  • Tetsuya Yagi
  • Takashi Yaguchi
  • Takenori Yoshikawa
  • Takuya Takeichi
  • Masashi Akiyama
  • Yohei Yamaguchi
  • Daisuke Koyama
  • Seitaro Terakura
  • Tetsuya Nishida
  • Hitoshi Kiyoi
  • Rinsho Ketsueki.2019;60(12):1641-1646. doi: 10.11406/rinketsu.60.1641.

肺癌に対する新規EGFR L858Rキナーゼ阻害剤としてのルテオリン-7-グルコシドとエピカテキンガレートの同定。ドッキングとシミュレーションに基づく研究

Identification of luteolin -7-glucoside and epicatechin gallate from , as novel EGFR L858R kinase inhibitors against lung cancer: Docking and simulation-based study.
  • Priyanka Maiti
  • Mahesha Nand
  • Tushar Joshi
  • Muthannan Andavar Ramakrishnan
  • Subhash Chandra
  • J. Biomol. Struct. Dyn..2020 Jun;:1-10. doi: 10.1080/07391102.2020.1784791.Epub 2020-06-24.

外傷と出血性ショックで肺組織内の5-リポキシゲナーゼと5-リポキシゲナーゼ活性化蛋白質の分子会合が活性化されることを明らかにした

Trauma and hemorrhagic shock activate molecular association of 5-lipoxygenase and 5-lipoxygenase-Activating protein in lung tissue.
  • Geoffrey R Nunns
  • John R Stringham
  • Fabia Gamboni
  • Ernest E Moore
  • Miguel Fragoso
  • Gregory R Stettler
  • Christopher C Silliman
  • Anirban Banerjee
  • J. Surg. Res..2018 09;229:262-270. S0022-4804(18)30188-4. doi: 10.1016/j.jss.2018.03.023.Epub 2018-05-05.

国の栄養研究の強化:新たに調整された連邦政府の研究努力と権限のための根拠と選択肢

Strengthening national nutrition research: rationale and options for a new coordinated federal research effort and authority.
  • Sheila E Fleischhacker
  • Catherine E Woteki
  • Paul M Coates
  • Van S Hubbard
  • Grace E Flaherty
  • Daniel R Glickman
  • Thomas R Harkin
  • David Kessler
  • William W Li
  • Joseph Loscalzo
  • Anand Parekh
  • Sylvia Rowe
  • Patrick J Stover
  • Angie Tagtow
  • Anthony Joon Yun
  • Dariush Mozaffarian
  • Am. J. Clin. Nutr..2020 Jul;nqaa179. doi: 10.1093/ajcn/nqaa179.Epub 2020-07-20.

アンデスの深層人口史の古生物学的再構築

A Paleogenomic Reconstruction of the Deep Population History of the Andes.
  • Nathan Nakatsuka
  • Iosif Lazaridis
  • Chiara Barbieri
  • Pontus Skoglund
  • Nadin Rohland
  • Swapan Mallick
  • Cosimo Posth
  • Kelly Harkins-Kinkaid
  • Matthew Ferry
  • Éadaoin Harney
  • Megan Michel
  • Kristin Stewardson
  • Jannine Novak-Forst
  • José M Capriles
  • Marta Alfonso Durruty
  • Karina Aranda Álvarez
  • David Beresford-Jones
  • Richard Burger
  • Lauren Cadwallader
  • Ricardo Fujita
  • Johny Isla
  • George Lau
  • Carlos Lémuz Aguirre
  • Steven LeBlanc
  • Sergio Calla Maldonado
  • Frank Meddens
  • Pablo G Messineo
  • Brendan J Culleton
  • Thomas K Harper
  • Jeffrey Quilter
  • Gustavo Politis
  • Kurt Rademaker
  • Markus Reindel
  • Mario Rivera
  • Lucy Salazar
  • José R Sandoval
  • Calogero M Santoro
  • Nahuel Scheifler
  • Vivien Standen
  • Maria Ines Barreto
  • Isabel Flores Espinoza
  • Elsa Tomasto-Cagigao
  • Guido Valverde
  • Douglas J Kennett
  • Alan Cooper
  • Johannes Krause
  • Wolfgang Haak
  • Bastien Llamas
  • David Reich
  • Lars Fehren-Schmitz
  • Cell.2020 May;181(5):1131-1145.e21. S0092-8674(20)30477-3. doi: 10.1016/j.cell.2020.04.015.Epub 2020-05-07.

DNA二本鎖切断部の機能的転写プロモーターがダメージ応答因子のRNA駆動型相分離を媒介している

Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors.
  • Fabio Pessina
  • Fabio Giavazzi
  • Yandong Yin
  • Ubaldo Gioia
  • Valerio Vitelli
  • Alessandro Galbiati
  • Sara Barozzi
  • Massimiliano Garre
  • Amanda Oldani
  • Andrew Flaus
  • Roberto Cerbino
  • Dario Parazzoli
  • Eli Rothenberg
  • Fabrizio d'Adda di Fagagna
  • Nat. Cell Biol..2019 10;21(10):1286-1299. 10.1038/s41556-019-0392-4. doi: 10.1038/s41556-019-0392-4.Epub 2019-09-30.

アリールメチルイソシアニドおよびアリールメチルアミンとキサンタートエステルの反応:カルバモチオエートの意外な合成法を提案した

The reaction of arylmethyl isocyanides and arylmethylamines with xanthate esters: a facile and unexpected synthesis of carbamothioates.
  • Narasimhamurthy Rajeev
  • Toreshettahally R Swaroop
  • Ahmad I Alrawashdeh
  • Shofiur Rahman
  • Abdullah Alodhayb
  • Seegehalli M Anil
  • Kuppalli R Kiran
  • Chandra
  • Paris E Georghiou
  • Kanchugarakoppal S Rangappa
  • Maralinganadoddi P Sadashiva
  • Beilstein J Org Chem.2020;16:159-167. doi: 10.3762/bjoc.16.18.Epub 2020-02-03.

繁殖期の開始時に測定された窒素および硫黄の再固定化関連パラメータは、Nおよび/またはS制限供給下で栽培されたナタネ(Brassica napus L.)において、NおよびS施肥を調整するための早期指標となるか?

Do nitrogen- and sulphur-remobilization-related parameters measured at the onset of the reproductive stage provide early indicators to adjust N and S fertilization in oilseed rape (Brassica napus L.) grown under N- and/or S-limiting supplies?
  • Yacine Akmouche
  • Jeanne Cheneby
  • Mickael Lamboeuf
  • Nicolas Elie
  • Anne Laperche
  • Jessica Bertheloot
  • Philippe D'Hooghe
  • Jacques Trouverie
  • Jean-Christophe Avice
  • Philippe Etienne
  • Sophie Brunel-Muguet
  • Planta.2019 Dec;250(6):2047-2062. 10.1007/s00425-019-03284-2. doi: 10.1007/s00425-019-03284-2.Epub 2019-09-25.

Remind Me To Remember.認知症と軽度の認知障害を持つ高齢者のための新しいスマートフォンリマインダーアプリケーションのパイロット研究

Remind Me To Remember: A pilot study of a novel smartphone reminder application for older adults with dementia and mild cognitive impairment.
  • Katherine Hackett
  • Sarah Lehman
  • Ross Divers
  • Matthew Ambrogi
  • Likhon Gomes
  • Chiu C Tan
  • Tania Giovannetti
  • Neuropsychol Rehabil.2020 Jul;:1-29. doi: 10.1080/09602011.2020.1794909.Epub 2020-07-20.