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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

耐性グラム陰性菌による感染症の危険性がある患者から採取した細菌サーベイランス分離株に対するceftolozan-tazobactamおよびコンパレータの活性

Activity of ceftolozane-tazobactam and comparators when tested against bacterial surveillance isolates collected from patients at risk of infections caused by resistant gram-negative pathogens.
  • Michael A Pfaller
  • Dee Shortridge
  • S J Ryan Arends
  • Leonard R Duncan
  • Jennifer M Streit
  • Robert K Flamm
  • Diagn. Microbiol. Infect. Dis..2020 Jun;98(1):115101. S0732-8893(20)30478-8. doi: 10.1016/j.diagmicrobio.2020.115101.Epub 2020-06-06.

シスプラチン誘発性急性腎障害におけるメチルグリオキサールとD-乳酸の役割また、このようなメカニズムを解明するためには、DNAを用いたプロテオミクス解析が重要であることを明らかにしました

Methylglyoxal and D-lactate in cisplatin-induced acute kidney injury: Investigation of the potential mechanism via fluorogenic derivatization liquid chromatography-tandem mass spectrometry (FD-LC-MS/MS) proteomic analysis.
  • Shih-Ming Chen
  • Tsung-Hui Chen
  • Hui-Ting Chang
  • Tzu-Yao Lin
  • Chia-Yu Lin
  • Pei-Yun Tsai
  • Kazuhiro Imai
  • Chien-Ming Chen
  • Jen-Ai Lee
  • PLoS ONE.2020;15(7):e0235849. PONE-D-20-05819. doi: 10.1371/journal.pone.0235849.Epub 2020-07-10.

単一インプラント再建のためのインプラントアバットメント選択の臨床的推奨事項。カスタマイズされたセラミックおよび金属製のソリューションと標準化されたセラミックおよび金属製のソリューション

Clinical Recommendations for Implant Abutment Selection for Single-Implant Reconstructions: Customized vs Standardized Ceramic and Metallic Solutions.
  • Cristina Zarauz
  • Joao Pitta
  • Guillermo Pradies
  • Irena Sailer
  • Int J Periodontics Restorative Dent.2020 Jan/Feb;40(1):31-37. doi: 10.11607/prd.3913.

ワシントン州キング郡で救急医療サービスを受けるコロナウイルス疾患2019(COVID-19)患者の臨床的特徴

Clinical Characteristics of Patients With Coronavirus Disease 2019 (COVID-19) Receiving Emergency Medical Services in King County, Washington.
  • Betty Y Yang
  • Leslie M Barnard
  • Jamie M Emert
  • Christopher Drucker
  • Leilani Schwarcz
  • Catherine R Counts
  • David L Murphy
  • Sally Guan
  • Kosuke Kume
  • Karen Rodriquez
  • Tracie Jacinto
  • Susanne May
  • Michael R Sayre
  • Thomas Rea
  • JAMA Netw Open.2020 07;3(7):e2014549. 2767993. doi: 10.1001/jamanetworkopen.2020.14549.Epub 2020-07-01.

サリノマイシンで処理した石川県子宮内膜癌細胞株におけるVEGF-A-DおよびVEGFR-1-3発現の変異と抗血管新生・リンパ管新生効果の評価

Evaluation of Variances in VEGF-A-D and VEGFR-1-3 Expression in the Ishikawa Endometrial Cancer Cell Line Treated with Salinomycin and An-ti-Angiogenic/Lymphangiogenic Effect.
  • Piotr Kras
  • Karol Talkowski
  • Beniamin Oskar Grabarek
  • Nina Dziobek
  • Dariusz Boroń
  • Marcin Oplawski
  • Curr Pharm Biotechnol.2020 Jul;CPB-EPUB-108031. doi: 10.2174/1389201021666200710093519.Epub 2020-07-09.

DNGR-1樹状細胞による死細胞関連抗原の交差提示は、マウスの慢性的な移植片拒絶に寄与する

Cross-presentation of dead-cell-associated antigens by DNGR-1 dendritic cells contributes to chronic allograft rejection in mice.
  • Saidou Balam
  • Rebecca Kesselring
  • Eggenhofer Elke
  • Stephanie Blaimer
  • Katja Evert
  • Matthias Evert
  • Hans J Schlitt
  • Edward K Geissler
  • Janneke van Blijswijk
  • Sonia Lee
  • Caetano Reis E Sousa
  • Stefan M Brunner
  • Stefan Fichtner-Feigl
  • Eur. J. Immunol..2020 Jul;doi: 10.1002/eji.201948501.Epub 2020-07-08.

遺伝子組換え食品酵素ホスホリパーゼCの安全性評価

Safety evaluation of the food enzyme phospholipase C from a genetically modified (strain PRF).
  • Vittorio Silano
  • José Manuel Barat Baviera
  • Claudia Bolognesi
  • Beat Johannes Brüschweiler
  • Pier Sandro Cocconcelli
  • Riccardo Crebelli
  • David Michael Gott
  • Konrad Grob
  • Evgenia Lampi
  • Alicja Mortensen
  • Gilles Rivière
  • Inger-Lise Steffensen
  • Christina Tlustos
  • Henk Van Loveren
  • Laurence Vernis
  • Holger Zorn
  • Lieve Herman
  • Francesca Marcon
  • Giovanni Bernasconi
  • Ana Gomes
  • Yi Liu
  • Andrew Chesson
  • EFSA J.2019 Apr;17(4):e05682. EFS25682. doi: 10.2903/j.efsa.2019.5682.Epub 2019-04-26.

繰り返しの麻酔薬曝露の間隔を長くすることで、生後間もないマウスのシナプス変化が長期的に減少することが示唆された

Increasing the interval between repeated anesthetic exposures reduces long-lasting synaptic changes in late postnatal mice.
  • Xianshu Ju
  • Jianchen Cui
  • Yulim Lee
  • Sangil Park
  • Boohwi Hong
  • Sungho Yoo
  • Yoon Hee Kim
  • Youngkwon Ko
  • Chaeseong Lim
  • Sun Yeul Lee
  • Gi Ryang Kweon
  • Jun Young Heo
  • Woosuk Chung
  • J. Neurochem..2020 Jul;doi: 10.1111/jnc.15121.Epub 2020-07-08.

スマートフォンプラットフォームによる肝移植片生検における非アルコール性脂肪性肝疾患病変の正確な評価。概念実証

Accurate assessment of nonalcoholic fatty liver disease lesions in liver allograft biopsies by a smartphone platform: A proof of concept.
  • Manuela Cesaretti
  • Jocelyn Gal
  • Charles Bouveyron
  • Alberto Diaspro
  • Eric Fontas
  • Andrea Antonini
  • Rodolphe Anty
  • Antonio Iannelli
  • Stephanie Patouraux
  • Microsc. Res. Tech..2020 Jul;doi: 10.1002/jemt.23478.Epub 2020-07-01.

DSM 32159由来のフモニシン・エステラーゼの豚・家禽用飼料添加剤としての安全性と有効性

Safety and efficacy of fumonisin esterase from DSM 32159 as a technological feed additive for pigs and poultry.
  • Guido Rychen
  • Gabriele Aquilina
  • Giovanna Azimonti
  • Vasileios Bampidis
  • Maria de Lourdes Bastos
  • Georges Bories
  • Andrew Chesson
  • Pier Sandro Cocconcelli
  • Gerhard Flachowsky
  • Jürgen Gropp
  • Boris Kolar
  • Maryline Kouba
  • Marta López-Alonso
  • Secundino López Puente
  • Baltasar Mayo
  • Fernando Ramos
  • Maria Saarela
  • Roberto Edoardo Villa
  • Robert John Wallace
  • Pieter Wester
  • Giovanna Martelli
  • Derek Renshaw
  • Boet Glandorf
  • Lieve Herman
  • Sirpa Kärenlampi
  • Jaime Aguilera
  • Gloria López-Gálvez
  • Alberto Mantovani
  • EFSA J.2018 May;16(5):e05269. EFS25269. doi: 10.2903/j.efsa.2018.5269.Epub 2018-05-17.

ノイラミニダーゼI223R/H275Y関連抗ウイルス多剤耐性インフルエンザウイルス検出用A4抗体の開発

Development of A4 antibody for detection of neuraminidase I223R/H275Y-associated antiviral multidrug-resistant influenza virus.
  • Kyeonghye Guk
  • Hyeran Kim
  • Miyeon Lee
  • Yoon-Aa Choi
  • Seul Gee Hwang
  • Gaon Han
  • Hye-Nan Kim
  • Hongki Kim
  • Hwangseo Park
  • Dongeun Yong
  • Taejoon Kang
  • Eun-Kyung Lim
  • Juyeon Jung
  • Nat Commun.2020 Jul;11(1):3418. 10.1038/s41467-020-17246-w. doi: 10.1038/s41467-020-17246-w.Epub 2020-07-09.

モチリパームはSDラットにおける酸化ストレスの抑制とNrf2/HO-1経路の調節を介して固定化ストレス誘発性精巣機能障害を改善します

MOTILIPERM Ameliorates Immobilization Stress-Induced Testicular Dysfunction via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway in SD Rats.
  • Keshab Kumar Karna
  • Kiran Kumar Soni
  • Jae Hyung You
  • Na Young Choi
  • Hye Kyung Kim
  • Chul Young Kim
  • Sung Won Lee
  • Yu Seob Shin
  • Jong Kwan Park
  • Int J Mol Sci.2020 Jul;21(13). E4750. doi: 10.3390/ijms21134750.Epub 2020-07-03.

ペギル化インターフェロン-αとヌクレオス(t)イデオロギーアナログ治療の併用は、ヌクレオス(t)イデオロギーアナログを経験したB型慢性肝炎患者のナチュラルキラー細胞の活性を高めた

Combination of pegylated-interferon-alpha and nucleos(t)ide analogue treatment enhances the activity of natural killer cells in nucleos(t)ide analogue experienced chronic hepatitis B patients.
  • Xichen Pang
  • Li Zhang
  • Nianqiu Liu
  • Bin Liu
  • Zhiwei Chen
  • Hu Li
  • Min Chen
  • Mingli Peng
  • Hong Ren
  • Peng Hu
  • Clin. Exp. Immunol..2020 Jul;doi: 10.1111/cei.13486.Epub 2020-07-07.

妊娠中のSARS-CoV-2感染およびCOVID-19疾患重症化予防におけるヒドロキシクロロキンの有効性と安全性(COVID-Preg):無作為化プラセボ対照試験の試験計画書の構造化された要約

Hydroxychloroquine efficacy and safety in preventing SARS-CoV-2 infection and COVID-19 disease severity during pregnancy (COVID-Preg): a structured summary of a study protocol for a randomised placebo controlled trial.
  • Raquel González
  • Laura García-Otero
  • Clara Pons-Duran
  • Elena Marbán-Castro
  • Anna Goncé
  • Elisa Llurba
  • Maria Del Mar Gil
  • Miguel Ángel Rodríguez-Zambrano
  • Haily Chen
  • Máximo Ramírez
  • Azucena Bardají
  • Clara Menendez
  • Trials.2020 Jul;21(1):607. 10.1186/s13063-020-04557-y. doi: 10.1186/s13063-020-04557-y.Epub 2020-07-02.

異なる生体材料で培養した歯根膜細胞の骨形成能、脂肪形成能、軟骨形成能、セメント形成能の比較

Comparison of the osteogenic, adipogenic, chondrogenic and cementogenic differentiation potential of periodontal ligament cells cultured on different biomaterials.
  • C C Barrera-Ortega
  • L Hoz-Rodríguez
  • H Arzate
  • A Fonseca-García
  • J Pérez-Alvarez
  • S E Rodil
  • Mater Sci Eng C Mater Biol Appl.2017 Jul;76:1075-1084. S0928-4931(16)32115-4. doi: 10.1016/j.msec.2017.03.213.Epub 2017-03-24.

感染症のモデル化と治療法の検証のためのヒト胚性幹細胞と患者特定の誘導多能性幹細胞からの完全な多細胞型肺オルガノイドの生成

Generation of Complete Multi-Cell Type Lung Organoids From Human Embryonic and Patient-Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics Validation.
  • Sandra L Leibel
  • Rachael N McVicar
  • Alicia M Winquist
  • Walter D Niles
  • Evan Y Snyder
  • Curr Protoc Stem Cell Biol.2020 09;54(1):e118. doi: 10.1002/cpsc.118.

レジン変性グラスアイオノマーセメントの齲蝕象牙質に対する微小引張接着強さに及ぼす3種類のフッ化銀ジアミン塗布プロトコルの影響.

Effect of three silver diamine fluoride application protocols on the microtensile bond strength of resin-modified glass ionomer cement to carious dentin in primary teeth.
  • Savil Ramachandra Uchil
  • Baranya Shrikrishna Suprabha
  • Ethel Suman
  • Ramya Shenoy
  • Srikant Natarajan
  • Arathi Rao
  • J Indian Soc Pedod Prev Dent.2020 Apr-Jun;38(2):138-144. JIndianSocPedodPrevDent_2020_38_2_138_288217. doi: 10.4103/JISPPD.JISPPD_159_20.

細胞の分化とリプログラミングにおけるゲノムワイドなRループのランドスケープ

Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming.
  • Pengze Yan
  • Zunpeng Liu
  • Moshi Song
  • Zeming Wu
  • Wei Xu
  • Kuan Li
  • Qianzhao Ji
  • Si Wang
  • Xiaoqian Liu
  • Kaowen Yan
  • Concepcion Rodriguez Esteban
  • Weimin Ci
  • Juan Carlos Izpisua Belmonte
  • Wei Xie
  • Jie Ren
  • Weiqi Zhang
  • Qianwen Sun
  • Jing Qu
  • Guang-Hui Liu
  • Cell Rep.2020 Jul;32(1):107870. S2211-1247(20)30851-2. doi: 10.1016/j.celrep.2020.107870.

がん患者におけるうつ病および不安の症状に対するコーピングスキル訓練の効果とモデレーター。集計データおよび個別の患者データのメタアナリシス

Effects and moderators of coping skills training on symptoms of depression and anxiety in patients with cancer: Aggregate data and individual patient data meta-analyses.
  • L M Buffart
  • M A C Schreurs
  • H J G Abrahams
  • J Kalter
  • N K Aaronson
  • P B Jacobsen
  • R U Newton
  • K S Courneya
  • J Armes
  • C Arving
  • A M Braamse
  • Y Brandberg
  • J Dekker
  • R J Ferguson
  • M F Gielissen
  • B Glimelius
  • M M Goedendorp
  • K D Graves
  • S P Heiney
  • R Horne
  • M S Hunter
  • B Johansson
  • L L Northouse
  • H S Oldenburg
  • J B Prins
  • J Savard
  • M van Beurden
  • S W van den Berg
  • J Brug
  • H Knoop
  • I M Verdonck-de Leeuw
  • Clin Psychol Rev.2020 Jun;80:101882. S0272-7358(20)30070-2. doi: 10.1016/j.cpr.2020.101882.Epub 2020-06-25.

人種は動物性タンパク質代謝物である1-メチルヒスチジンと中年成人の血圧との関連を修飾する:Bogalusa Heart Study

Race modifies the association between animal protein metabolite 1-methylhistidine and blood pressure in middle-aged adults: the Bogalusa Heart Study.
  • Alexander C Razavi
  • Lydia A Bazzano
  • Jiang He
  • Seamus P Whelton
  • Casey M Rebholz
  • Camilo Fernandez
  • Marie Krousel-Woods
  • Changwei Li
  • Mengyao Shi
  • Jovia L Nierenberg
  • Shengxu Li
  • Jason Kinchen
  • Xuenan Mi
  • Tanika N Kelly
  • J. Hypertens..2020 Jul;doi: 10.1097/HJH.0000000000002571.Epub 2020-07-06.

プラチナ抵抗性の転移性尿路粘膜がん患者に対するカボザンチニブ:非盲検、単施設、第2相試験

Cabozantinib in patients with platinum-refractory metastatic urothelial carcinoma: an open-label, single-centre, phase 2 trial.
  • Andrea B Apolo
  • Rosa Nadal
  • Yusuke Tomita
  • Nicole N Davarpanah
  • Lisa M Cordes
  • Seth M Steinberg
  • Liang Cao
  • Howard L Parnes
  • Rene Costello
  • Maria J Merino
  • Les R Folio
  • Liza Lindenberg
  • Mark Raffeld
  • Jeffrey Lin
  • Min-Jung Lee
  • Sunmin Lee
  • Sylvia V Alarcon
  • Akira Yuno
  • Nancy A Dawson
  • Kimaada Allette
  • Arpita Roy
  • Dinuka De Silva
  • Molly M Lee
  • Tristan M Sissung
  • William D Figg
  • Piyush K Agarwal
  • John J Wright
  • Yangmin M Ning
  • James L Gulley
  • William L Dahut
  • Donald P Bottaro
  • Jane B Trepel
  • Lancet Oncol..2020 Jul;S1470-2045(20)30202-3. doi: 10.1016/S1470-2045(20)30202-3.Epub 2020-07-06.

単細胞ゲノミクスは、骨髄性新生物における突然変異のエピスタシスから逃れるための遺伝的・分子的基盤を明らかにした

Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms.
  • Justin Taylor
  • Xiaoli Mi
  • Khrystyna Dilai North
  • Moritz Binder
  • Alexander Penson
  • Terra L Lasho
  • Katherine Knorr
  • Michael Haddadin
  • Bo Liu
  • Joseph Pangallo
  • Salima Benbarche
  • Daniel Howard Wiseman
  • Ayalew Tefferi
  • Stephanie Halene
  • Yang Liang
  • Mrinal M Patnaik
  • Robert K Bradley
  • Omar Abdel-Wahab
  • Blood.2020 Jul;blood.2020006868. doi: 10.1182/blood.2020006868.Epub 2020-07-08.

両側慢性硬膜下血腫の片側退院後の対側血腫増殖に対する再手術のリスクを予測する予後スコアリングシステムの開発

Development of a prognostic scoring system to predict risk of reoperation for contralateral hematoma growth after unilateral evacuation of bilateral chronic subdural hematoma.
  • John J Y Zhang
  • Shilin Wang
  • Aaron Song Chuan Foo
  • Ming Yang
  • Boon Leong Quah
  • Ira Siyang Sun
  • Zhi Xu Ng
  • Kejia Teo
  • Boon Chuan Pang
  • Eugene Weiren Yang
  • Sein Lwin
  • Ning Chou
  • Shiong Wen Low
  • Tseng Tsai Yeo
  • Thomas Santarius
  • Vincent Diong Weng Nga
  • J Clin Neurosci.2020 Jun;S0967-5868(20)31317-5. doi: 10.1016/j.jocn.2020.06.009.Epub 2020-06-29.

たばこを吸う人、電子ニコチン送達システムを使用する人、歯周炎の有無にかかわらず非喫煙者から採取した歯肉下口腔バイオフィルムサンプルから分離された病原性細菌の定量化

Quantification of pathogenic bacteria in the subgingival oral biofilm samples collected from cigarette-smokers, individuals using electronic nicotine delivery systems and non-smokers with and without periodontitis.
  • Fahad M Aldakheel
  • Shatha A Alduraywish
  • Poojdev Jhugroo
  • Chitra Jhugroo
  • Darshan Devang Divakar
  • Arch. Oral Biol..2020 Jun;117:104793. S0003-9969(20)30171-0. doi: 10.1016/j.archoralbio.2020.104793.Epub 2020-06-06.

チオアダタンセリン及びそのジアルキル化生成物の合成と生物学的評価を行った

Synthesis and biological evaluation of thioadatanserin and its dialkylated products as partial 5-HTR agonists and 5-HTR antagonists for potential use in depression and anxiety disorders.
  • Colleen A Evans
  • Andrea Zuluaga
  • Diego Vasquez Matute
  • Sarah Baradaran-Noviri
  • Natalia Perez-Cervantes
  • Maxime A Siegler
  • Bioorg. Med. Chem. Lett..2020 Aug;30(16):127358. S0960-894X(20)30469-8. doi: 10.1016/j.bmcl.2020.127358.Epub 2020-06-17.