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日本語AIでPubMedを検索

歯科医師情報サイトTop / PubMed論文検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。
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みんなが読んでいる論文

イミノシュガーAMP-DNMはGLP1を介して満腹感を改善し、褐色脂肪組織を活性化する

The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1.
  • Daniela Herrera Moro Chao
  • Yanan Wang
  • Ewout Foppen
  • Roelof Ottenhoff
  • Cindy van Roomen
  • Edwin T Parlevliet
  • Marco van Eijk
  • Marri Verhoek
  • Rolf Boot
  • Andre R Marques
  • Saskia Scheij
  • Mina Mirzaian
  • Sander Kooijman
  • Kirstin Jansen
  • Dawei Wang
  • Clarita Mergen
  • Randy J Seeley
  • Matthias H Tschöp
  • Herman Overkleeft
  • Patrick C N Rensen
  • Andries Kalsbeek
  • Johannes M F G Aerts
  • Chun-Xia Yi
  • Diabetes.2019 12;68(12):2223-2234. db19-0049. doi: 10.2337/db19-0049.Epub 2019-10-02.

FDA承認の抗エストロゲン剤Faslodexを用いてERβ/アンジオポエチン-2/Tie-2シグナルを介した血管新生を標的とし、RCCにおけるスニチニブの感度を向上させる

Targeting the ERβ/Angiopoietin-2/Tie-2 signaling-mediated angiogenesis with the FDA-approved anti-estrogen Faslodex to increase the Sunitinib sensitivity in RCC.
  • Junfei Gu
  • Yong Zhang
  • Zhenwei Han
  • Lei Gao
  • Jinfeng Cui
  • Yin Sun
  • Yuanjie Niu
  • Bosen You
  • Chi-Ping Huang
  • Chawnshang Chang
  • Xiaolu Wang
  • Shuyuan Yeh
  • Cell Death Dis.2020 May;11(5):367. 10.1038/s41419-020-2486-0. doi: 10.1038/s41419-020-2486-0.Epub 2020-05-14.

ニコチンのピロリジニウム環のメチルスキャンにより、α7およびα4β2ニコチン性アセチルコリン受容体との相互作用に有意な差異が示された

A Methyl Scan of the Pyrrolidinium Ring of Nicotine Reveals Significant Differences in its Interactions with α7 and α4β2 Nicotinic Acetylcholine Receptors.
  • Hong Xing
  • Kristin W Andrud
  • Ferenc Soti
  • Anne Rouchaud
  • Stephan C Jahn
  • Ziang Lu
  • Yeh-Hyon Cho
  • Sophia Habibi
  • Patrick Corsino
  • Svetoslav Slavov
  • James R Rocca
  • Jon S Lindstrom
  • Ron J Lukas
  • William Kem
  • Mol. Pharmacol..2020 May;mol.119.118786. doi: 10.1124/mol.119.118786.Epub 2020-05-30.

キク科Arctium lappa L. (Arctium lappa L.)のマンソニ桿菌および単純ヘルペスウイルス-1に対するin vitroの分裂毒殺および抗ウイルス活性

In vitro schistosomicidal and antiviral activities of Arctium lappa L. (Asteraceae) against Schistosoma mansoni and Herpes simplex virus-1.
  • Mirna Meana Dias
  • Ohana Zuza
  • Lorena R Riani
  • Priscila de Faria Pinto
  • Pedro Luiz Silva Pinto
  • Marcos P Silva
  • Josué de Moraes
  • Ana Caroline Z Ataíde
  • Fernanda de Oliveira Silva
  • Alzira Batista Cecílio
  • Ademar A Da Silva Filho
  • Biomed. Pharmacother..2017 Oct;94:489-498. S0753-3322(17)32153-4. doi: 10.1016/j.biopha.2017.07.116.Epub 2017-08-03.

ホルモン状態は、タモキシフェン治療を受けた乳癌患者におけるタモキシフェンとその主要代謝物の血漿中曝露に影響を与える

Hormonal status affects plasma exposure of tamoxifen and its main metabolites in tamoxifen-treated breast cancer patients.
  • João Paulo Bianchi Ximenez
  • Jurandyr Moreira de Andrade
  • Maria Paula Marques
  • Eduardo Barbosa Coelho
  • Guilherme Suarez-Kurtz
  • Vera Lucia Lanchote
  • BMC Pharmacol Toxicol.2019 12;20(Suppl 1):81. 10.1186/s40360-019-0358-y. doi: 10.1186/s40360-019-0358-y.Epub 2019-12-19.

敗血症性ショック患者におけるトリプトファン経路の異化産物（セロトニン、5-ヒドロキシインドラ酢酸、キヌレニン）および酵素（モノアミンオキシダーゼおよびインドールアミン2,3ジオキシゲナーゼ）：前向き観察研究対健常対照

Tryptophan pathway catabolites (serotonin, 5-hydroxyindolacetic acid, kynurenine) and enzymes (monoamine oxidase and indole amine 2,3 dioxygenase) in patients with septic shock: A prospective observational study versus healthy controls.
  • Gilles Troché
  • Matthieu Henry-Lagarrigue
  • Frédérique Soppelsa
  • Stephane Legriel
  • Aihem Yehia
  • Fabrice Bruneel
  • Jean-Pierre Bédos
  • Odile Spreux-Varoquaux
  • Medicine (Baltimore).2020 May;99(19):e19906. 00005792-202005080-00010. doi: 10.1097/MD.0000000000019906.

劣化ウランと湾岸戦争による疾病劣化ウランと湾岸戦争症候群の背後にある可能性のあるメカニズムについての最新情報とコメントを掲載しています

Depleted uranium and Gulf War Illness: Updates and comments on possible mechanisms behind the syndrome.
  • Geir Bjørklund
  • Lyudmila Pivina
  • Maryam Dadar
  • Yuliya Semenova
  • Md Mostafizur Rahman
  • Salvatore Chirumbolo
  • Jan Aaseth
  • Environ. Res..2020 02;181:108927. S0013-9351(19)30724-8. doi: 10.1016/j.envres.2019.108927.Epub 2019-11-19.

運動とキヌレニン経路。現在の知見と、持久力トレーニングとレジスタンストレーニングの急性効果を比較した無作為化クロスオーバー試験の結果

Exercise and the Kynurenine pathway: Current state of knowledge and results from a randomized cross-over study comparing acute effects of endurance and resistance training.
  • Niklas Joisten
  • Felix Kummerhoff
  • Christina Koliamitra
  • Alexander Schenk
  • David Walzik
  • Luca Hardt
  • Andre Knoop
  • Mario Thevis
  • David Kiesl
  • Alan J Metcalfe
  • Wilhelm Bloch
  • Philipp Zimmer
  • Exerc Immunol Rev.2020;26:24-42.

中国人乳癌患者におけるタモキシフェン関連内分泌症状。試験プロトコール臨床試験（SPIRIT準拠）

Tamoxifen-related endocrine symptoms in Chinese patients with breast cancer: Study protocol clinical trial (SPIRIT Compliant).
  • Carmen Wing Han Chan
  • Christine Miaskowski
  • Alexandra McCarthy
  • Mary Miu Yee Waye
  • Winnie Yeo
  • Winnie Kwok Wai So
  • Kai Chow Choi
  • Stephen Kwok Wing Tsui
  • Judy Yuet Wa Chan
  • Medicine (Baltimore).2020 Feb;99(8):e19083. 00005792-202002210-00011. doi: 10.1097/MD.0000000000019083.

サルコイドーシスにおける関節、筋肉、骨の有病率、分布、臨床的意義：F-FDG-PET/CT試験

Prevalence, distribution and clinical significance of joints, muscles and bones in sarcoidosis: an F-FDG-PET/CT study.
  • Spyros A Papiris
  • Effrosyni D Manali
  • Andriana I Papaioannou
  • Alexandros Georgakopoulos
  • Lykourgos Kolilekas
  • Nikoletta K Pianou
  • Maria Kallergi
  • Anastasia Papaporfyriou
  • Maria Kallieri
  • Vasiliki Apollonatou
  • Georgia Papadaki
  • Katerina Malagari
  • Nikolaos L Kelekis
  • Spyros G Pneumatikos
  • Sofia Chatziioannou
  • Expert Rev Respir Med.2020 Jun;:1-8. doi: 10.1080/17476348.2020.1775587.Epub 2020-06-17.

クルクミンは相乗的にラットの慢性デルタメトリン腎毒性に対するシタグリプチンの保護効果を増強する。プロ炎症性サイトカインとNrf2/HO-1経路への影響

Curcumin synergistically potentiates the protective effect of sitagliptin against chronic deltamethrin nephrotoxicity in rats: Impact on pro-inflammatory cytokines and Nrf2/Ho-1 pathway.
  • Wenbin Shi
  • Daisong Zhang
  • Lei Wang
  • Nagaraja Sreeharsha
  • Yushan Ning
  • J. Biochem. Mol. Toxicol..2019 Oct;33(10):e22386. doi: 10.1002/jbt.22386.Epub 2019-08-27.

死後CTの導入は日常診療において従来の剖検率に悪影響を与えることなく死後検診率を向上させる：実施研究

Introduction of postmortem CT increases the postmortem examination rate without negatively impacting the rate of traditional autopsy in daily practice: an implementation study.
  • Max G Mentink
  • Frans C H Bakers
  • Casper Mihl
  • Max J Lahaye
  • Roger J M W Rennenberg
  • Bart G H Latten
  • Bela Kubat
  • Paul A M Hofman
  • J. Clin. Pathol..2020 Jul;jclinpath-2020-206734. doi: 10.1136/jclinpath-2020-206734.Epub 2020-07-16.

湾岸戦争病、ポストＨＰＶワクチン接種症候群、およびマクロファージ性筋膜炎。ワクチン誘発性自己免疫性自律神経失調症と関連している可能性のある同様の障害状態

Gulf war illness, post-HPV vaccination syndrome, and Macrophagic Myofasciitis. Similar disabling conditions possibly linked to vaccine-induced autoimmune dysautonomia.
  • Manuel Martinez-Lavin
  • Melina Tejada-Ruiz
  • Autoimmun Rev.2020 Jul;:102603. S1568-9972(20)30167-1. doi: 10.1016/j.autrev.2020.102603.Epub 2020-07-10.

積極的なサーベイランスが検討されている、またはすでに行われている患者における前立腺のマルチパラメトリックMRIの利用。画像ガイド下の標的生検との相関

Utilization of Multiparametric MRI of Prostate in Patients under Consideration for or Already in Active Surveillance: Correlation with Imaging Guided Target Biopsy.
  • Jinxing Yu
  • Ann S Fulcher
  • Sarah Winks
  • Mary A Turner
  • William Behl
  • Anna Lee Ware
  • Nitai D Mukhopadhyay
  • Candice Kim
  • Christopher Jackson
  • Harnek S Bajaj
  • Lance J Hampton
  • Diagnostics (Basel).2020 Jun;10(7). E441. doi: 10.3390/diagnostics10070441.Epub 2020-06-29.

camptodactyly-arthropathy-coxa vara-pericarditis (CACP)症候群の無関係11家族35例の遺伝子型-フェノタイプ調査

Genotype-phenotype investigation of 35 patients from 11 unrelated families with camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome.
  • Saliha Yilmaz
  • Dilek Uludağ Alkaya
  • Özgür Kasapçopur
  • Kenan Barut
  • Ekin S Akdemir
  • Cemre Celen
  • Mark W Youngblood
  • Katsuhito Yasuno
  • Kaya Bilguvar
  • Murat Günel
  • Beyhan Tüysüz
  • Mol Genet Genomic Med.2018 03;6(2):230-248. doi: 10.1002/mgg3.364.Epub 2018-02-04.

後側脛骨プラトー骨折に対する修正された前側方アプローチによる低侵襲リムプレート骨合成を関節鏡下で補助し、3次元的にモデル化した

Arthroscopically assisted and three-dimensionally modeled minimally invasive rim plate osteosynthesis via modified anterolateral approach for posterolateral tibial plateau fractures.
  • Marco Delcogliano
  • Roberto Marin
  • Luca Deabate
  • Davide Previtali
  • Giuseppe Filardo
  • Michele Francesco Surace
  • Christian Candrian
  • Paolo Gaffurini
  • Knee.2020 Jun;27(3):1093-1100. S0968-0160(20)30049-1. doi: 10.1016/j.knee.2020.02.011.Epub 2020-04-01.

マディヤ・プラデシュ州の施設出産を促進するための州主導の「Janani Sahayogi Yojana」官民パートナーシッププログラムへの参加：民間産科医パートナーからの見解

Participation in the state led 'Janani Sahayogi Yojana' public private partnership program to promote facility births in Madhya Pradesh, India: views from private obstetrician partners.
  • Vishal Diwan
  • Sudhir Chandra Joshi
  • Kate Jehan
  • Ayesha De Costa
  • BMC Health Serv Res.2019 Aug;19(1):599. 10.1186/s12913-019-4409-2. doi: 10.1186/s12913-019-4409-2.Epub 2019-08-24.

コロナウイルス疾患における胸部CT所見の標準化診断基準の使用の初期結果 2019

Initial Results of the Use of a Standardized Diagnostic Criteria for Chest Computed Tomography Findings in Coronavirus Disease 2019.
  • João Manoel Miranda Magalhães Santos
  • Ana Paula Alves Fonseca
  • Eduardo Pinheiro Zarattini Anastacio
  • Fernanda Formagio Minenelli
  • Conrado Furtado de Albuquerque Cavalcanti
  • Gustavo Borges da Silva Teles
  • J Comput Assist Tomogr.2020 Jul;doi: 10.1097/RCT.0000000000001054.Epub 2020-07-07.

FcRnは、FcγRsではなく、FcRnがヒトIgG抗体の母体-胎児トランスプラセン輸送を駆動する

FcRn, but not FcγRs, drives maternal-fetal transplacental transport of human IgG antibodies.
  • Sara Borghi
  • Stylianos Bournazos
  • Natalie K Thulin
  • Chao Li
  • Anna Gajewski
  • Robert W Sherwood
  • Sheng Zhang
  • Eva Harris
  • Prasanna Jagannathan
  • Lai-Xi Wang
  • Jeffrey V Ravetch
  • Taia T Wang
  • Proc. Natl. Acad. Sci. U.S.A..2020 Jun;117(23):12943-12951. 2004325117. doi: 10.1073/pnas.2004325117.Epub 2020-05-27.

ショウジョウバエのFUSとAubが神経障害におけるpiRNAの生合成に果たす新たな役割

Novel roles of Drosophila FUS and Aub responsible for piRNA biogenesis in neuronal disorders.
  • Keiko Tsuji Wakisaka
  • Ryo Tanaka
  • Tomoki Hirashima
  • Yuuka Muraoka
  • Yumiko Azuma
  • Hideki Yoshida
  • Takahiko Tokuda
  • Satoshi Asada
  • Kojiro Suda
  • Kenji Ichiyanagi
  • Seiko Ohno
  • Masanobu Itoh
  • Masamitsu Yamaguchi
  • Brain Res..2019 04;1708:207-219. S0006-8993(18)30646-2. doi: 10.1016/j.brainres.2018.12.028.Epub 2018-12-19.

4つのリソソーム貯蔵疾患におけるストップコドンリードスルー治療のためのアミノグリコシドおよび非アミノグリコシド化合物の評価

Evaluation of Aminoglycoside and Non-Aminoglycoside Compounds for Stop-Codon Readthrough Therapy in Four Lysosomal Storage Diseases.
  • Marta Gómez-Grau
  • Elena Garrido
  • Mónica Cozar
  • Víctor Rodriguez-Sureda
  • Carmen Domínguez
  • Concepción Arenas
  • Richard A Gatti
  • Bru Cormand
  • Daniel Grinberg
  • Lluïsa Vilageliu
  • PLoS ONE.2015;10(8):e0135873. PONE-D-15-09543. doi: 10.1371/journal.pone.0135873.Epub 2015-08-19.

Atriplex inflataのMolluscicidal and LARVICIDAL ACTIVITIES OF AERIAL PARTS INTO THE MOLLUSK Galba truncatula, INTERMEDIATE HOST OF Fasciola hepatica

MOLLUSCICIDAL AND LARVICIDAL ACTIVITIES OF Atriplex inflata AERIAL PARTS AGAINST THE MOLLUSK Galba truncatula, INTERMEDIATE HOST OF Fasciola hepatica.
  • Néjia Hamed
  • Fatma Njeh
  • Mohamed Damak
  • Ali Ayadi
  • Raoudha Mezghani-Jarraya
  • Hayet Hammami
  • Rev. Inst. Med. Trop. Sao Paulo.2015 Dec;57(6):473-9. S0036-46652015000600473. doi: 10.1590/S0036-46652015000600003.

非小細胞肺癌患者におけるマウスダブルミニッツ2ホモログとP73の発現は成長停止DNA損傷誘導遺伝子45αとは相関がなかった：STROBE準拠の研究

The expression of mouse double minute 2 homolog and P73 had no correlation with growth arrest DNA damage-inducible gene 45α in patients with non-small-cell lung carcinoma: A STROBE-compliant study.
  • Bo Wang
  • Chaoyang Liang
  • Huifeng Liu
  • Jixing Lin
  • Bailin Wang
  • Kaijie Fan
  • Zhipeng Ren
  • Bin Wang
  • Tong Li
  • Kang Qi
  • Xiaodong Tian
  • Medicine (Baltimore).2019 Dec;98(51):e17944. 00005792-201912200-00007. doi: 10.1097/MD.0000000000017944.

転写ダイナミクスがポリ(A)テールとRNA分解機械の発現を制御してmRNAレベルをバランスさせる

Transcription Dynamics Regulate Poly(A) Tails and Expression of the RNA Degradation Machinery to Balance mRNA Levels.
  • Boris Slobodin
  • Anat Bahat
  • Urmila Sehrawat
  • Shirly Becker-Herman
  • Binyamin Zuckerman
  • Amanda N Weiss
  • Ruiqi Han
  • Ran Elkon
  • Reuven Agami
  • Igor Ulitsky
  • Idit Shachar
  • Rivka Dikstein
  • Mol. Cell.2020 May;78(3):434-444.e5. S1097-2765(20)30190-8. doi: 10.1016/j.molcel.2020.03.022.Epub 2020-04-14.

血液学的悪性腫瘍（アダマンチン）患者における復職のための医療社会的要因の分析：「パイロット研究」の結果

Analysis of medico-social factors for return to work among patients presenting with haematological malignancy (adamantine): results of a 'pilot study'.
  • Bénédicte Clin
  • Natacha Heutte
  • Mathilde Boulanger
  • Xavier Troussard
  • Edouard Cornet
  • Ghandi Laurent Damaj
  • Véronique Bouvier
  • Anne-Valérie Guizard
  • Guy Launoy
  • Idlir Licaj
  • BMC Res Notes.2020 Jul;13(1):313. 10.1186/s13104-020-05149-4. doi: 10.1186/s13104-020-05149-4.Epub 2020-07-02.

RNA-seqトランスクリプトーム解析により、リポ多糖類（LPS）注射後のヒト末梢血単核細胞（PBMCs）におけるLTR-レトロトランスポゾンの変調が明らかになった

RNA-seq transcriptome analysis reveals LTR-retrotransposons modulation in Human Peripheral Blood Mononuclear Cells (PBMCs) after Lipopolysaccharides (LPS) injection.
  • Maria Paola Pisano
  • Olivier Tabone
  • Maxime Bodinier
  • Nicole Grandi
  • Julien Textoris
  • François Mallet
  • Enzo Tramontano
  • J. Virol..2020 Jul;JVI.00587-20. doi: 10.1128/JVI.00587-20.Epub 2020-07-15.

RIFM香料成分安全性評価、3-(4-メチル-3-ペンテニル)-3-シクロヘキセン-1-カルボニトリル、CAS登録番号68084-04-8

RIFM fragrance ingredient safety assessment, 3-(4-methyl-3-pentenyl)-3-cyclohexene-1-carbonitrile, CAS registry number 68084-04-8.
  • A M Api
  • D Belsito
  • D Botelho
  • M Bruze
  • G A Burton
  • J Buschmann
  • M L Dagli
  • M Date
  • W Dekant
  • C Deodhar
  • M Francis
  • A D Fryer
  • L Jones
  • K Joshi
  • S La Cava
  • A Lapczynski
  • D C Liebler
  • D O'Brien
  • A Patel
  • T M Penning
  • G Ritacco
  • J Romine
  • N Sadekar
  • D Salvito
  • T W Schultz
  • I G Sipes
  • G Sullivan
  • Y Thakkar
  • Y Tokura
  • S Tsang
  • Food Chem. Toxicol..2020 Jul;:111491. S0278-6915(20)30381-1. doi: 10.1016/j.fct.2020.111491.Epub 2020-07-04.

拡大する生殖細胞ABL1関連先天性心欠損・骨格奇形症候群の臨床表現型

The expanding clinical phenotype of germline ABL1-associated congenital heart defects and skeletal malformations syndrome.
  • Chun-An Chen
  • Emeline Crutcher
  • Harinder Gill
  • Tanya N Nelson
  • Laurie A Robak
  • Marjolijn C J Jongmans
  • Rolph Pfundt
  • Chitra Prasad
  • Roberta A Berard
  • Madeleine Fannemel
  • Eirik Frengen
  • Doriana Misceo
  • Keri Ramsey
  • Yaping Yang
  • Christian P Schaaf
  • Xia Wang
  • Hum. Mutat..2020 Jul;doi: 10.1002/humu.24075.Epub 2020-07-09.

ステージIおよびIIのトリプルネガティブ乳癌に対するネオアジュバント化学療法の回避と期間短縮：Ki-67標識指数とアポクリン型病変の認識の重要性

Avoidance and Period-Shortening of Neoadjuvant Chemotherapy Against Triple-Negative Breast Cancer in Stages I and II: Importance of Ki-67 Labeling Index and the Recognition of Apocrine-Type Lesions.
  • Koichi Kubouchi
  • Kyosuke Shimada
  • Takamichi Yokoe
  • Yutaka Tsutsumi
  • Technol. Cancer Res. Treat..2020 Jan-Dec;19:1533033820943246. doi: 10.1177/1533033820943246.